Protein Complementarity May Offer New Insights Into Autoimmune Diseases Aug 15, 2008
14, 2008) The discovery of "complementary" antibodies against plasminogen in patients with blood vessel inflammation caused by anti-neutrophil cytoplasmic autoantibodies (ANCAs) may lead to new approaches to research, testing, and treatment of ANCA vasculitis and other autoimmune diseases, suggests a new article ... The researchers looked for complementary proteins in a group of patients with a rare autoimmune disease called ANCA vasculitis ... In patients with ANCA vasculitis, the ANCAs attack... (Science Daily)
Shauna Karen Carson McCurdyNov. 24, 1953 - July 23, 2008 Jul 31, 2008
Memorial contributions may be made to the Vasculitis Foundation, PO Box 28660, Kansas City MO 64188 (). Because I could not stop for Death. (Ontario Argus Observer, OR)
Clyde T. Johnston Jun 23, 2008
In lieu of flowers, the family requests donations are made to the Vasculitis Foundation (www. vasculitisfoundation. (New Iberia, LA)
Neuromyelitis Optica Jun 5, 2008
Devic's Syndrome: Multiple Sclerosis Variant Often Confused with MS. NMO antibodies are key to diagnosis. (Suite101.com)
LETTER: Arthritis Walk will help fight Sjogren's Syndrome May 3, 2008
When internal organs are involved, it can cause arthritis, myositis, gastrointestinal problems, interstitial cystitis or renal problems, vasculitis and neurologic symptoms that cause central nervous system disorders such as cranial and peripheral neuropathies. This condition also causes cognitive dysfunction and memory problems as the disorder progresses, along with greater risk of developing lymphoma. (Mattoon Journal-Gazette, IL)
Gemma didn't have to die Apr 20, 2008
Kawasaki disease, an uncommon illness that mostly affects children under five, causes inflammation of small blood vessels known as vasculitis. In extreme cases the coronary arteries swell, which can block the blood supply to the heart. (Sydney Morning Herald -- Australia)
* Pediatricians warn parents against Kawasaki disease Apr 11, 2008
First discovered in 1967 by Tomisaku Kawasaki in Japan, the disease is a poorly understood self-limited vasculitis that affects many organs, including the skin and mucous membranes, lymph nodes, blood vessel walls and the heart. Lu said parents and pediatricians should pay extra attention if children in their care have a fever for more than five days and show other symptoms such as a rash, swollen hands and feet, red eyes, swollen lymph glands in the neck, and irritation and inflammation of the... (Taipei Times, Taiwan -- World)
Some Docs Latching Onto Leeches Mar 5, 2008
Dr. Dong-Ha Han nicknamed "doctor leech" for his eight years of research on medical leeches says he can treat patients with vasculitis, skin ulcer, atopic dermatitis, rheumatic arthritis, migraine and gout. His toolbox includes leeches that are starved for six months. (ABC News)
A Nazi past casts a pall on name of a disease Jan 23, 2008
"The name adds insult to injury," said Shaw, who prefers calling her condition vasculitis, the broader term for the family of diseases that includes Wegener's ... At the moment, the most precise candidate is ANCA-associated granulomatous vasculitis, which does not exactly trip off the tongue. (International Herald Tribune -- Health)
Biomarkers For Inflammatory Disease Dec 8, 2007
Kawasaki disease, an acute, self-limited vasculitis, is the leading cause of acquired heart disease in children in developed countries, but its aetiologic and pathogenic mechanisms remain unclear. A team of researchers led by David Relman, Stanford University, US, and Jane Burns, University of California at San Diego, US, characterized the gene expression patterns that occur in the blood cells of patients with this disease. (Science Daily)
Existing Drugs Show Promise For Treating End-stage Renal Disease In Lupus Nov 29, 2007
At the end of the eight-week study, 90 percent of the mice in the non-treatment group had renal vasculitis, inflammation of the tiny blood vessels in the kidney that can lead to kidney failure, compared to 30 percent in the treatment group. In addition, 60 percent in the non-treatment group had high levels of protein in the urine (a sign of kidney disease), compared to 22 percent in the treatment group. (Science Daily)
United States Nov 18, 2007
He has three auto-immune disorders: Crohn's disease, a chronic inflammation of the bowel, total alopecia, and cerebral vasculitis, an immune system-related narrowing of blood vessels in the brain. The new tests suggest I inhaled about 4,000 particles of DU,' Donnelly says. (Guardian Unlimited)
Charleston woman diagnosed with rare disease reaches out to help others Nov 3, 2007
It is a form of vasculitis, a disorder that causes inflammation in blood vessels and affects various organs, including lungs, upper respiratory and kidneys. The condition is believed to affect about one in 1 million people. (Mattoon Journal-Gazette, IL)
Doctor says Wegener's granulomatosis is difficult to diagnose, requires aggressive treatment Nov 3, 2007
It is an example of vasculitis, a condition of inflammation of the blood vessels, he said ... Parkison to start vasculitis support group ... A Charleston woman diagnosed in March 2005 with a rare disease called Wegener s granulomatosis is working toward becoming a chapter leader for the Vasculitis Foundation. (Mattoon Journal-Gazette, IL)
Antiphospholipid Syndrome Oct 21, 2007
Pauci-immune vasculitis. APS Associated Nephropathy. (Suite101.com)
Mayo Clinic clarifies diagnosis for serious blood vessel disease of brain and spinal cord Oct 19, 2007
Primary central nervous system vasculitis (PCNSV) can best be identified through a combination of diagnostic techniques consisting of angiography (imaging the cerebral arteries), brain biopsy and other laboratory studies ... Primary central nervous system vasculitis is difficult to diagnose because it is not a single disease, but a variable syndrome that appears to consist of several distinct subsets of different diseases that can mimic other less-serious conditions, thus eluding treatment ...... (EurekAlert!)
Rams soccer standout battles West Nile Virus Oct 13, 2007
According to the National Institute of Allergy and Infectious Diseases, Wegener's granulomatosis is an uncommon disease in which the blood vessels are inflamed (vasculitis). This inflammation damages important organs of the body by limiting blood flow to those organs and destroying normal tissue. (Rio Rancho Observer, NM)
Lessons from a Genomewide Association Study of Rheumatoid Arthritis Sep 21, 2007
Occasionally there is systemic involvement, which can include vasculitis in various organs and pulmonary fibrosis. The disease has multifactorial causes to which genetic and environmental factors are thought to contribute. (New England Journal of Medicine)
Potential New Way to Treat Inflammatory Disease Found Sep 14, 2007
If the drugs effects are confirmed in clinical trials, they could be used against several types of inflammation that include acute vasculitis, an inflammation of blood vessels that can affect any organ in the body. Also, the drugs have been used successfully to treat acute coronary syndrome, which refers to certain types of heart attack and unstable angina. (Newsmax)
A Woman with Headaches, Weakness, and Strokelike Episodes Jul 12, 2007
NEJM -- Case 21-2007 -- A 58-Year-Old Woman with Headaches, Weakness, and Strokelike Episodes. Please for full text and personal services. (New England Journal of Medicine)
Immunosuppressant Drugs Jul 5, 2007
Cyclophosphamide (Cytoxan), which is primarily used in systemic lupus erythematosus, autoimmune hemolytic anemia, Wegener s granulomatosis, and other forms of vasculitis. Cyclosporine (Sandimmune, Neoral) is primarily used in psoriasis soriasis. (Suite101.com)
Communication between Physicians and Patients in the Era of E-Medicine Jun 14, 2007
Dr. Stone, formerly director of the Vasculitis Center and an associate professor of medicine at Johns Hopkins University School of Medicine, Baltimore, is now a deputy editor for rheumatology at UpToDate, Waltham, MA.. . (New England Journal of Medicine)
Test Case Linking Vaccines and Autism Reaches Federal Court Jun 5, 2007
Within days, Ryan had an intense allergic reaction and developed vasculitis. "That means the valves in your veins leak," Gaudino says. (Law.com)
Kawasaki's Disease May 13, 2007
Immune-Mediated Vasculitis in Children ... Another perplexing fact is that , unlike other forms of vasculitis, patients with Kawasaki s disease are not easily treated with corticosteroids. (Suite101.com)
Summary for Patients May 1, 2007
Giant cell arteritis (GCA, also called temporal arteritis) involves inflammation of large and medium-sized arteries (vasculitis). This condition occurs in elderly people and can lead to sudden blindness. (Annals of Internal Medicine)
* Sports Briefs Apr 12, 2007
Slutskaya has been treated for vasculitis, an ailment which results in the inflammation of the blood vessels. ICE HOCKEY Blackhawks win lottery The Chicago Blackhawks won the National Hockey League draft lottery on Tuesday, gaining the first overall selection in June's draft. (Taipei Times, Taiwan -- World)
What is Lupus? Apr 4, 2007
Inflammation of the blood vessels, known as vasculitis, can develop in many organs impairing blood supply to the tissue. This inadequate oxygen supply to the cells can lead to further inflammation and destruction of the tissue. (Suite101.com)
Human Parvovirus B19 Infection Apr 4, 2007
Human Parvovirus B19 has been linked to a number of different autoimmune diseases, including vasculitis and connective tissue disorders ... The immune response in Parvovirus infection also causes the induction of tumor necrosis factor alpha (TNF- ), a cytokine involved in the development of ANCA positive vasculitis syndromes. (Suite101.com)
Cogan's Syndrome Mar 30, 2007
Other symptoms include vasculitis, nausea, vertigo, poor balance, fever, fatigue, weight loss, vomiting, light sensitivity, and a bilateral blurring of vision ... Vasculitis in Cogan s syndrome can cause major organ damage, and in rare instances it can be fatal ... Vasculitis, if present, can be detected with imaging tests and confirmed with tissue studies. (Suite101.com)
An elusive diagnosis with a risk of cancer Mar 29, 2007
Recent studies have quantified the risk, finding that dermatomyositis patients face a threefold risk of cancer, while patients with polymyositis face a 40 percent increase in risk, said Dr. Stuart M. Levine, co-director of the Hopkins vasculitis center and an author of a recent paper on the subject ... Levine, of the vasculitis center, said the muscle cells might be like "innocent bystanders," accidentally harmed during the immune system's assault on the tumor. (International Herald Tribune -- Health)
Rheumatoid Arthritis Today Mar 26, 2007
Systemic effects of RA include cardiac (heart) involvement including pericarditis (inflammation of the sac surrounding the heart), myocarditis (inflammation of the heart muscle), and rheumatic nodules in myocardial tissue; cutaneous vasculitis, neurological disease (mononeuritis multiplex, a condition of neuropathy affecting multiple systems such as the nerves of the hands and feet), and diffuse lung problems such as pleural effusion and pulmonary vasculitis. About 30 percent of patients develop... (Suite101.com)
Churg-Strauss Syndrome Mar 22, 2007
A Unique Combination of Vasculitis, Eosinophilia, and Asthma ... Small vessel necrotizing (causing tissue damage and destruction) Vasculitis ... These P-ANCA or myeloperoxidase autoantibodies, are also seen in other conditions of vasculitis affecting small to medium vessels. (Suite101.com)
Vasculitis Update Mar 21, 2007
Vasculitis includes more than 20 organ specific and systemic disorders that cause inflammation in the veins and arteries as well as the organs that these vessels supply. Vasculitis, which is sometimes called angiitis, is a condition of blood vessel inflammation ... Conditions of vasculitis cause inflammation of veins and arteries along with their smaller tributaries, the venules and arterioles. (Suite101.com)
Mixed Connective Tissue Disease Feb 25, 2007
Complications include fever, which occurs as a sign of infection, vasculitis, pancreatitis, appendicitis, bowel perforations, trigeminal neuralgia, respiratory distress syndrome, stroke, and secondary Sjogren s syndrome. Although some researchers recognize MCTD as a subset or early stage of SLE, most researchers consider MCTD a distinct clinical entity with infrequent renal complications. (Suite101.com)
Connective Tissue Disorders Feb 24, 2007
Various forms of vasculitis including , and. Mixed connective tissue disease. (Suite101.com)
Book Review "Don't Leave Me This Way" Feb 21, 2007
After a diagnosis of vasculitis, a specialist Garrison nicknames "Dr. Jerk" recommends chemotherapy once a month for the rest of her life. Garrison initially resists treatment with the strong chemicals but reluctantly consents. (Galesburg The Paper, IL)
Benefits of a Gluten-Free Diet Feb 20, 2007
The Living Without article "All in your head" lists the following as conditions possibly associated with gluten: congenital heart disease, recurrent pericarditis (inflammation of the sack around the heart), lung disease, inflammatory bowel disease, autoimmune hepatitis (liver disease), primary biliary cirrhosis (gallbladder dysfunction), Addison's disease (kidney and adrenal dysfunction), systemic lupus erythematosus (an autoimmune disease), vasculitis (inflammation of the blood vessels),... (Suite101.com)
The Riddle of Kawasaki Disease Feb 15, 2007
How can an illness look like an infectious disease but not have a recoverable agent; look like an immune-mediated vasculitis but not be easily treated with corticosteroids; and look like a benign, self-limited illness but be the leading cause of acquired heart disease in children. The answers to the riddle continue to elude us. (New England Journal of Medicine)
Rashes and Hives Feb 5, 2007
Persons with autoimmune disorders, especially thyroid disorders, lupus and Sjogren's, are at risk for rashes, hives and urticarial vasculitis ... Urticarial Vasculitis ... Chronic urticaria may also be associated with a leukocytoclastic (white blood cell-mediated) vasculitis confined to skin or to a wider area of connective tissue. (Suite101.com)
Inflazyme Pharmaceuticals Ltd., to Appear On MN1.com Jan 10, 2007
Inflazyme's proprietary class of PDE4 Inhibitors, which could also be used to treat asthma and COPD, do not cause nausea or emesis (vomiting) in human subjects in clinical studies or vasculitis (inflammation of the blood vessels in the body) in preclinical studies. These compounds are at the research stage and could be readily advanced into the clinic. (Primezone Releases)
Explore Stroke Symptoms Jan 4, 2007
Strokes: Causes, Symptoms And Treatment, FYI: Learn More About The Causes Of And Medical Care For Strokes - CBS News. Strokes: Causes, Symptoms And Treatment. (CBS News -- Evening News)
Another drug to fight bone loss in men Dec 12, 2006
Men being treated with steroid medications for such conditions as asthma, rheumatoid arthritis and vasculitis are predisposed to osteoporosis. Those being treated for prostate cancer with medications that lower testosterone levels, smokers and men who use alcohol excessively are also at risk. (Newsday -- Health)
Subsequent Course of Rituxan(R) Improved Outcomes in Rheumatoid Arthritis Patients Who Inadequately Responded to TNF Antagonist Therapy Nov 13, 2006
In addition to RA, Rituxan is being studied in other autoimmune diseases with significant unmet medical needs, including systemic lupus erythematosus, lupus nephritis, multiple sclerosis and ANCA-associated vasculitis. Rituxan, discovered by Biogen Idec, received FDA approval in November 1997 for the treatment of relapsed or refractory, low-grade or follicular, CD20-positive, B-cell NHL. It was also approved in the European Union under the trade name MabThera(R) in June 1998. (PR Newswire)
Google Searches Out the Diagnoses, Stat Nov 11, 2006
They cited a case of ehrlichiosis for which Google suggested amyotrophy, vasculitis diagnosed by Google as uveitis, and a rare presentation of endometriosis that Google suggested was tuberous sclerosis. Before reading the NEJM's diagnosis, the researchers examined the top 30 to 50 search results from Google using search terms selected from the article. (MedPage Today)
Congressman, wife claim home incident report inaccurate Nov 3, 2006
John Sweeney also blamed health problems related to vasculitis, an inflammatory reaction in blood vessels. He was hospitalized for the condition in late February. (Albany Times Union)
Who Knew: 'House' Doing 'God's Work'? Oct 30, 2006
At one point, a representative from an association for sufferers of an inflammatory condition called vasculitis stood up and thanked the show for calling attention to the malady. While none of the patients of cranky, brilliant Dr. Gregory House (Hugh Laurie) ever wind up having vasculitis, House and his team of doctors (Omar Epps, Jennifer Morrison, Jesse Spencer) often mention it as a possible diagnosis while trying to solve medical puzzles each week ... "Vasculitis was mentioned in the pilot... (The Ledger)
Brief, High-dose Steroid Treatment Offers Extended Relief To Giant Cell Arteritis Patients Oct 11, 2006
The results will be good news at Emory's new Vasculitis Clinic, the only center for inflammatory blood vessel diseases in the Southeast. "We can do better in treating this disease, and what we do at the beginning is very important for the long-term prognosis of patients," says Dr. Weyand. (Science Daily)
Network of Support Oct 10, 2006
Doctors diagnosed him with Wegener s disease, a rare form of Vasculitis, on his 27th birthday ... According to a brochure from the Vasculitis Foundation, Vasculitis is an inflammation of the blood vessels, arteries, veins or capillaries ... Before Vessell ever passed away, the family began discussing ways to get the word out about Wegener s Disease and Vasculitis as a whole. (Dublin Courier Herald, GA)
Realty Times Contributor's Years Of Courage End Sadly Sep 21, 2006
Diagnosed with Wegener's Granulomatosis anca-positive vasculitis, a disease of the Lupus family in which healthy cells turn on themselves, causing capillaries to burst and the lungs to fill with blood, Crystal received what was in effect a life sentence. Most who contract the disease live a maximum of 15 years, and it's fatal in more than 90 percent of cases. (RealtyTimes)
A Woman with Painful Nodules on the Fingertips, Shortness of Breath, and Fatigue Sep 21, 2006
A biopsy specimen of the sole of her right foot showed intravascular fibrin thrombi without evidence of vasculitis. She was treated with prednisone, nifedipine, and. (New England Journal of Medicine)
Writers face hurdles when building a ‘House' Sep 5, 2006
Vasculitis, (an inflammation of blood vessels) you're going to hear as a possible diagnosis. Lupus, you're going to hear as a possible diagnosis. (Globe and Mail -- Entertainment)
A weekly House of horrors Sep 5, 2006
"There are certain conditions you're going to hear on our show on more than one occasion. Vasculitis (an inflammation of blood vessels), you're going to hear as a possible diagnosis. Lupus, you're going to hear as a possible diagnosis.". What you won't hear are ultra-obscure conditions with distinct symptoms, even though occasionally a member of Shore's writing staff will get fired up after stumbling across a medical rarity. (Toronto Star -- Arts)
A Man with Staphylococcal Bacteremia and Renal Failure Jun 29, 2006
ANCA-Associated Vasculitis. Systemic Lupus Erythematosus. (New England Journal of Medicine)
Improving the standard of rheumatology care in Europe Jun 22, 2006
Following a rigorous development process involving numerous multidisciplinary experts across Europe, recommendations for the management of hand osteoarthritis, systemic lupus erythematosus (SLE) and fibromyalgia have been proposed for endorsement by EULAR (The European League Against Rheumatism), along with recommendations for conducting clinical trials in SLE and systemic vasculitis. Professor Tore Kvien, EULAR president, stated: "The EULAR executive place great importance on the need to... (EurekAlert!)
Relapsing Polychondritis May 22, 2006
RPC usually occurs alone although it may occur in patients with generalized vasculitis (inflammation of blood vessels) or in patients with other autoimmune disorders ... Vasculitis may also occur as part of the disease process or as a consequence of another co-existing autoimmune disorder. (Suite101.com)
Determined Girl Walks With Hope May 12, 2006
Along with that, she has vasculitis and dermatomyositis, related conditions that cause more pain and inflammation. "Vasculitis inflames her blood vessels," her mother, Amy Brown, said. (The Ledger)
Lawmaker Chided for Going to Frat Party Apr 30, 2006
After several weeks in and out of the hospital, he was eventually diagnosed with vasculitis, an inflammation of blood vessels in the brain, and prescribed drugs to treat the problem. Sweeney is married with three children. (ABC 7 News, DC)
Cohen? Slutskaya? Figure skaters bring suspense to Turin Games Feb 23, 2006
Since then, she has overcome vasculitis, a circulatory disease that almost ended her career. She also considered retiring to spend more time with her mother, a dialysis patient. (San Jose Mercury News)
Bring on the ice queens Feb 10, 2006
She missed most of 2003 and 2004 with vasculitis, an inflammation of the blood vessels around her heart. Slutskaya willtry tobecome the first Russian woman to winOlympic gold in singles, and, as defending world champion, will be the favorite going in. (SportsIllustrated.CNN)
