Injuries might boost clot risk Jan 26, 2008
Lawrence estimates that the center performs 4,000 to 5,000 ultrasounds a year for patients with vascular diseases. Of particular concern, he says, is the study s questionnaire format, in which venous thrombosis patients and a control group were asked about their recollections of previous injuries. (Albany Democrat-Herald, OR)
Stroke, bone screens on Thursday Jan 16, 2008
These non-invasive, inexpensive and painless ultrasound tests help people identify their risk for stroke, vascular diseases or osteoporosis early enough for their physician to begin preventive procedures. For more information regarding the screenings or to schedule an appointment, those interested can call (877) 237-1377 or visit. (Coos Bay-North Bend The World, OR)
Lipoic acid could reduce atherosclerosis, weight gain Jan 15, 2008
reducing known risk factors for the development of atherosclerosis and other inflammatory vascular diseases in humans ... As a result, the authors concluded that lipoic acid may be a useful adjunct in the prevention and treatment of atherosclerotic vascular diseases. (EurekAlert!)
Low cancer risk for those with Down syndrome Jan 3, 2008
The basic biological mechanism, which affects blood vessel function and growth, may also underlie other so-called vascular diseases such as atherosclerosis, Folkman said. Folkman and other researchers believe people with Down produce extra endostatin naturally, but also that other genes play an important role. (MSNBC -- Health)
Cut down of fat intake, consume more vegetables Dec 30, 2007
She noted that the recent rise in non communicable diseases in the country has been as a result of the unhealthy lifestyle choices resulting in diseases such cardio vascular diseases, cancer, diabetes, obesity, mental illness and bone and muscular diseases, which are described as the greatest killers of the day. Ms Adjei said, to increase the quality of the Ghanaians diet during these festivities, fruits and vegetables should be increased in both quantity and quality to supply the vitamins,... (Ghana Web, Ghana)
What AM I? AM Is A Regulator Of Vascular System Functionality Dec 21, 2007
25, 2007) Low-density lipoprotein, a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a new report. The study reveals a link between. (Science Daily)
Small RNAs and Large DNA Viruses Dec 20, 2007
Moreover, CMV infection is a leading cause of birth defects and has been implicated in the acceleration of long-term vascular diseases such as atherosclerosis. Like infection with other herpesviruses, a primary CMV infection is followed by a lifelong persistent or latent state of the virus in the host. (New England Journal of Medicine)
ThromboGenics Presents Results of the Phase I Trial of TB-402 at the Prestigious American Society of Hematology Annual Meeting Dec 11, 2007
Professor Peter Verhamme, Department of Vascular Diseases, University of Leuven, who presented the results at the ASH meeting, commented: "The results from the first Phase I study with TB-402 show that this novel human monoclonal antibody is safe and well-tolerated, an important first step in the development of this new anticoagulant drug. Of equal importance, the results clearly indicate that TB-402 has the long half-life we predicted and a stable long-acting anticoagulant effect based on... (PR Newswire)
ED in Younger Men Usually Psychogenic Dec 4, 2007
We dont see much of vascular diseases, so more of the cases are a result of what is between the ears. You dont see a lot of erectile dysfunction in men under the age of 40. (Newsmax)
Erectile Dysfunction in Young Men Often Psychological Nov 27, 2007
We don t see much of vascular diseases so more of the cases are a result of what is between the ears. You don t see a lot of erectile dysfunction in men under the age of 40. (Fox News)
Arterial Vascular Disease Underdiagnosed, Undertreated In Older US Women Nov 23, 2007
(May 2, 2007) Migraines during pregnancy are strongly linked to vascular diseases, such as stroke and heart disease, according to new. (Jan. (Science Daily)
Shareholder Class Action Filed Against Micrus Endovascular Corporation by the Law Firm of Schiffrin Barroway Topaz & Kessler, LLP Nov 17, 2007
Micrus develops, manufactures, and markets implantable and disposable medical devices used in the treatment of cerebral vascular diseases. More specifically, the Complaint alleges that the Company failed to disclose and misrepresented the following material adverse facts which were known to defendants or recklessly disregarded by them: (1) that the Company was experiencing increased competition and seasonal slowing, which led to slower sales in North America; (2) that the Company was... (PR Newswire)
HEALTH NOTES / Memorable tips about forgetfulness Nov 16, 2007
A number of studies in recent years have suggested that vascular diseases heart disease and stroke may contribute to the development of AD, the severity of AD, or the development of multi-infarct dementia (also called vascular dementia). Don't smoke or abuse alcohol. (Cohasset Mariner, MA)
Looking at Glaucoma as a Systemic Disease Nov 12, 2007
Studies have found that patients with exfoliative glaucoma have a higher incidence of several other diseases, including Alzheimer's and vascular diseases. "The same genetic variation that affects the eye is probably active in all these other tissues," says Dr. Ritch. (PR Newswire)
5,000 Patients Treated With OrbusNeich's Genous(TM) Bio-engineered R Stent(TM) Now Enrolled in Real-Life Use Global Registry Nov 9, 2007
"Completing enrollment in this large registry is an important milestone in our clinical development," said Samuel Rasmussen, OrbusNeich's president and CEO. OrbusNeich designs, develops, manufactures and markets innovative medical devices for the treatment of vascular diseases. In addition to Genous OrbusNeich's products are stents, balloons and guiding catheters marketed under the names of Blazer(TM), R stent(TM), Sapphire(TM), Avita(TM), Avita HP(TM), SafeCut(TM), Lumina(TM) and Saffron. (PR Newswire)
ThromboGenics and BioInvent Announce Publication of Exciting Data on a Novel Class of Angiogenesis Inhibitors in Cell Nov 2, 2007
Desire Collen, CEO and Chairman of ThromboGenics, commented: "Today's publication in the prestigious journal Cell clearly highlights our ground-breaking research in the field of angiogenesis. The data in the Cell paper shows the potential of our novel anti-PlGF antibody, TB-403, based on its unique ability to block the development of new blood vessels, but only via mechanisms that exist in the diseased state. This mode of action, which is different from and complementary to current anti-VEGF... (PR Newswire)
* Results of mortality rate study surprise researchers Nov 1, 2007
89 times more likely to die because of vascular diseases and 1 ... 49 times more likely to die from vascular diseases. (Taipei Times, Taiwan -- World)
Contribution of cholesterol transporter to vascular disease Oct 26, 2007
Low-density lipoprotein, a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a report published online this week in EMBO reports. Low-density lipoprotein (LDL), a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a report published online this week in EMBO reports ... Vascular diseases such as thrombosis, stroke and heart attacks are associated with this... (EurekAlert!)
Erectile Dysfunction: A Harbinger of Heart Trouble Oct 6, 2007
And now a growing body of research ties erectile dysfunction to vascular diseases, such as coronary artery disease. "Erectile dysfunction is often caused by vascular disease," explained Dr. Ian Thompson, professor and chairman of the department of urology at the University of Texas Health Science Center at San Antonio. (U.S. News & World Report)
Chemokine Therapeutics Completes Patient Recruitment of CTCE-9908 Phase I/II Clinical Trial Oct 2, 2007
VANCOUVER, BRITISH COLUMBIA--(Marketwire - Oct. 2, 2007) - Chemokine Therapeutics Corp. (the "Company") (TSX: - ; OTCBB: - ), a biotechnology company developing chemokine-based therapies to treat cancer, blood disorders, and vascular diseases, announced today that the Company has completed recruitment of its Phase I/II clinical study using its lead compound CTCE-9908 with late stage cancer patients. Dosing is expected to be completed by the end of October 2007 with results reported by the end of... (CCNMatthews Press Releases)
Promising New Source Of Stem Cells: Mouse Testes Produce Wide Range Of Tissue Types Sep 25, 2007
If the same can be done with human cells, they say, adult stem cells may be a promising source of new therapies for men, for diseases such as vascular diseases, heart disease, Alzheimer's, Parkinson's, stroke, diabetes, and even cancer. Scientists have had good success in deriving pluripotent stem cell lines -- those with the ability to develop into multiple cell types -- from adult testes cells. (Science Daily)
Stem Cells from Testes Produce Wide Range of Tissue Types Sep 21, 2007
If the same can be done with adult testes stem cells from humans, they may offer a source of new therapies to treat men with health problems such as heart disease, vascular diseases, diabetes, stroke, Parkinson's, Alzheimer's, and even cancer, the researchers said. The study, by Howard Hughes Medical Institute scientists, is published in the Sept. 20 issue of the journal Nature. (MEDLINEplus)
Edwards Lifesciences gift to establish cardiovascular device research UCI, Sep. 12 Sep 13, 2007
The Edwards Lifesciences Center for Advanced Cardiovascular Technology will promote interaction and collaboration among students, faculty members and experts by incorporating both undergraduate and graduate programs related to heart and vascular diseases. The programs will be directed by UCI's Department of Biomedical Engineering, and will involve a variety of other disciplines, including students from the Integrated Nanosystems Research Facility, the California Institute for Telecommunications... (University of California Newswire, CA)
Rising early may be bad for the heart Sep 8, 2007
"Rising early to go to work or exercise might not be beneficial to health, but rather a risk for vascular diseases," said an abstract of the study. Dr V Mohan Kumar, vice-president of the World Federation of Sleep Research and Sleep Medicine Societies, told TOI that an adult needs a minimum of 6-8 hours of sleep everyday. (India Times, India -- Health/Science)
Early risers more likely to have heart problems Sep 7, 2007
"Rising early to go to work or exercise might not be beneficial to health, but rather a risk for vascular diseases," said the study. The study, conducted by researchers from several universities and hospitals in the western Japanese city of Kyoto, revealed a link between wake-up times and a person's cardiovascular condition. (Xinhuanet, China)
Little Shasta Valley rancher honored Sep 6, 2007
He is involved in a project of investigating the variation and opportunities to genetically select cattle for beef products that are more healthful especially as it relates to potential vascular diseases such as heart attacks. His work in this area includes participating as a cooperating producer with his calves. (Mount Shasta News, CA)
ThromboGenics Announces Successful Completion of Technology Transfer to Bharat Biotech for Production of Novel Thrombolytic Agent Sep 4, 2007
THR-100 is a thrombolytic agent developed for the treatment of acute myocardial infarction (AMI or heart attack) and other vascular diseases, based on its ability to dissolve blood clots ... Desire Collen, CEO of ThromboGenics, commented on today's announcement: "We are pleased that ThromboGenics and Bharat Biotech have successfully completed the technology transfer needed for the production of THR-100. Transfer of biopharmaceutical production technology from one company to another, or from one... (PR Newswire)
Dr. Robbert de Winter to Present Pros and Cons of Drug-Eluting Stents and the Benefits of Using an Alternative Pro-Healing Stent to European Cardiologists Aug 30, 2007
The best recent scientific developments and novel research will be presented to medical professionals who deal with cardiovascular diseases in the course of their professional activity. About OrbusNeich OrbusNeich designs, develops, manufactures and markets innovative medical devices for the treatment of vascular diseases. (PR Newswire)
MRI scans: Diagnostic tool grows in popularity Aug 29, 2007
It is likewise very valuable for the diagnosis of cancer, heart and vascular diseases. Wikipedia says that unlike X-rays and CT scans, MRI does not expose patients to any damaging forms of radiation. (Jakarta Post, Indonesia -- Features)
Q&A with Sandy Feather: Digging deep to protect healthy oak trees from infected ones Aug 25, 2007
Vascular diseases such as oak wilt are easily transmitted from infected trees to healthy ones through such shared tissue. If your neighbor's trees are within 50 feet of your trees, it is likely their roots have grafted together. (Pittsburgh Post-Gazette, PA)
Endologix Completes Enrollment in Powerlink Trial with 34 Millimeter Diameter Infrarenal Cuff Aug 21, 2007
Endologix, Inc. develops and manufactures minimally invasive treatments for vascular diseases. Endologix's Powerlink System is an endoluminal stent graft (ELG) for treating abdominal aortic aneurysms (AAA). (BusinessWire)
160 mln Chinese adults suffer from blood fat abnormality Aug 14, 2007
Cardiovascular diseases, the No. 1 killer for Chinese, causes about 3 million deaths in the country, or 40 percent of the annual deaths number, according to Zhao Dong, director of Beijing's municipal center for the control of heart, lung and vascular diseases. Abnormal blood lipid is one of the main factors causing cardiovascular problems, the expert said. (Xinhuanet, China)
OrbusNeich Expands Global Sales and Marketing Team Jul 30, 2007
OrbusNeich designs, develops, manufactures and markets innovative medical devices for the treatment of vascular diseases. The company's product portfolio includes the Genous Bio-engineered R stent, an antibody-coated device that is the first ever stent to capture a patient's endothelial progenitor cells (EPCs) to accelerate the natural healing process following placement. (PR Newswire)
Ev3 buys FoxHollow for $780M Jul 25, 2007
FoxHollow makes devices to treat arterial blockage, whereas ev3 makes devices to treat vascular diseases. The companies said that the combined company would have a market capitalization of approximately $1. (Twin Cities Business Journal, MN)
Medical Device Companies Announce Merger Jul 23, 2007
Merger plans were announced Sunday by medical device companies based in Minnesota and California that develop and market minimally invasive devices to treat vascular diseases and disorders. Plymouth-based ev3 Inc. and FoxHollow Technologies Inc. of Redwood City, Calif. (WCCO.com, MN)
Drinking may not be so bad, say scientists Jul 11, 2007
Both help in preventing strokes and vascular diseases such as heart disease, and both have been shown to increase cognitive function. Just to give a few examples. (ABC Online)
BMH brings Dr. Yue to city Jul 8, 2007
His interest is not only with cardiac disease, but also peripheral vascular diseases, such as renal arteries, carotid arteries and leg circulation ... Additionally he is board certified in Internal Medicine and Cardiovascular Diseases and has contributed to a variety of prestigious publications since 1989. (DeRidder Beauregard Daily News, LA)
Erectile Dysfunction May 29, 2007
Vascular diseases and diabetes and, in a few cases, hormonal level imbalance, are all examples of physical problems. Within the physical problem category we should also include obesity, alcohol, smoking, the effects of some recreational drugs and some medicines. (Suite101.com)
Chemokine Therapeutics Amends License Agreement With UBC May 24, 2007
VANCOUVER, BRITISH COLUMBIA--(CCNMatthews - May 24, 2007) - Chemokine Therapeutics Corp. ("Chemokine" or the "Company") (TSX: - ; OTCBB: - ), a biotechnology company developing chemokine-based therapies to treat cancer, blood disorders, and vascular diseases, today announced that it has amended certain terms of its license agreement with The University of British Columbia ("UBC") dated September 22, 1999. Under the terms of the license agreement with UBC, Chemokine was required to meet... (CCNMatthews Press Releases)
Urodynamix Cancels Proposed Share Consolidation May 23, 2007
The Company is currently developing NIRS applications for urological conditions in men and women, intra-abdominal hypertension and compartment syndrome, erectile dysfunction and vascular diseases. The Company's disruptive technology has the potential to affect the diagnosis and treatment of more than 200 million people worldwide. (CCNMatthews Press Releases)
Ways to prevent memory loss May 22, 2007
Vascular diseases -- heart disease and stroke -- can contribute to the development and severity of dementia and Alzheimer's disease. Don't smoke or abuse alcohol: Smokers perform worse than nonsmokers in studies of memory and thinking skills. (Akron Beacon Journal, OH -- Living)
OrbusNeich Receives CE Mark Approval for Blazer(TM) Cobalt Chromium Stent, Sapphire(TM) PTCA Dilatation Catheter, Lumina(TM) Guiding Catheter May 21, 2007
" OrbusNeich designs, develops, manufactures and markets innovative medical devices for the treatment of vascular diseases. The company's product portfolio includes the Genous(TM) Bio-engineered R stent, an antibody-coated device that is the first-ever stent to capture a patient's endothelial progenitor cells (EPCs) to accelerate the natural healing process following placement. Other products are stents, balloons and guiding catheters marketed under the names of Blazer, R stent(TM), Sapphire,... (PR Newswire)
Lifewire: More praise for the Mediterranean model May 19, 2007
Its purpose is to evaluate a series of hypotheses about men's health relating nutritional factors to the incidence of serious illnesses, such as cancer, heart disease, and other vascular diseases. The all-male study was designed to complement the all-female Nurses' Health Study, which examines similar hypotheses. (Bend Weekly)
Migraines During Pregnancy Linked To Stroke And Other Vascular Diseases May 3, 2007
Migraines during pregnancy are strongly linked to vascular diseases, such as stroke and heart disease, according to new research. Researchers looked at a national database of nearly 17 million women discharged for pregnancy deliveries from 2000-2003. (Science Daily)
Ev3 to raise $166.25M in secondary offering Apr 22, 2007
Ev3 is a global medical device company focused on catheter-based technologies for the endovascular treatment of vascular diseases and disorders. cwyant@bizjournals. (Twin Cities Business Journal, MN)
Chemokine Therapeutics announces 2006 financial and operating results Apr 17, 2007
TSX: CTI OTCBB: CHKT VANCOUVER, April 16 /PRNewswire-FirstCall/ - Chemokine Therapeutics Corp. (the "Company") (TSX:CTI, OTCBB:CHKT), a biotechnology company developing chemokine-based therapies to treat cancer, blood disorders, and vascular diseases, today announced highlights and the financial and operating results of the year ended December 31, 2006. 2006 Highlights: - Commencement and continued enrollment of subjects to the Phase Ib/II clinical study of CTCE-9908 to assess the safety and... (PR Newswire)
Scientists find major susceptibility genes for Crohn's disease Apr 17, 2007
Founded in 1954, the Montreal Heart Institute is Canada's largest and oldest institution dedicated to research, education and clinical care of cardiovascular diseases ... Its prime focus areas of research are vascular diseases, myocardial function and electrophysiology. (EurekAlert!)
Thrombogenics Announces License Agreement With Millipore for Commercialization of Stem Cell Medium Technology Apr 16, 2007
About ThromboGenics ThromboGenics is a biotechnology company focused on discovery and development of biopharmaceuticals for the treatment of a range of vascular diseases. The Company has several programs in Phase II clinical development including microplasmin, which is being evaluated as a treatment for vitreoretinal disorders and as a thrombolytic agent for vascular occlusive diseases, including acute stroke. (PR Newswire)
GO Capital Becomes Major Shareholder in ThromboGenics Mar 27, 2007
Desire Collen, CEO of ThromboGenics, said: "We are pleased that GO Capital, a highly regarded asset manager and experienced investor in the biotech space, has decided to acquire a significant position in ThromboGenics. This is an important vote of confidence in our product pipeline, our management team and our cutting edge science. We look forward to their long term support as we work to maximize the value of our late stage clinical pipeline, particularly microplasmin for the treatment of back... (PR Newswire)
Lotus CEO Announces Expansion Strategy to Reach China's Top Tier of Pharmaceuticals With Revenues Exceeding $100 Million Mar 21, 2007
One of the new drugs, already in the clinical trial stage, is classified as a 'National Class One New Drug' for cardiac vascular diseases. This drug is expected to deliver an effective and cheap alternative to the current costly drugs of the same category. (Primezone Releases)
Cholesterol dip linked to mental decline Mar 18, 2007
Kivipelto and colleagues believe that declining cholesterol after middle age may "reflect ongoing pathological processes in the brain." Nonetheless, they say the relationship between cholesterol and dementia is "controversial," and meanwhile, they point out, high cholesterol "carries risk even in old age, and results from clinical trials in vascular diseases support the benefit of lipid-lowering treatment in elderly patients.". SOURCE: Neurology, March 6, 2007. (Sydney Morning Herald -- World)
THELIN (sitaxentan sodium) Receives Australian Marketing Approval Mar 7, 2007
Our research and development programs are predominantly focused on the treatment and prevention of interrelated diseases of the vascular endothelium and exploit our expertise in the area of the intravascular inflammatory process, referred to as the inflammatory cascade, and vascular diseases. To learn more about Encysive Pharmaceuticals please visit our web site. (Primezone Releases)
Heart disease rate in the US on the rise Feb 17, 2007
Pearson TA, Blair SN, Daniels SR, et al. AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. American Heart Association Science Advisory and Coordinating Committee. (Food Consumer)
Lung transplant for Australian teenage girl Feb 16, 2007
This site contains information for professionals and the general public about heart and vascular diseases, lung diseases, blood diseases. - To build public awareness of lung cancer, four national cancer organizations are uniting to launch a nationwide lung cancer awareness campaign. (SpiritIndia)
Life Line Screenings to be offered Feb 15, 2007
The non-invasive ultrasound tests help people identify their risk for stroke, vascular diseases or osteoporosis early enough for their physician to begin preventive procedures. The First Baptist Church is located at 13560 N. State Highway 5 in Sunrise Beach. (Camdenton Lake Sun Leader, MO)
Poor people worse off following heart attack Feb 14, 2007
Patients in the lowest income quartile were more likely to be older, female and to have other illnesses such as diabetes and peripheral vascular diseases. Researchers first looked at who was more likely to have an angioplasty or coronary bypass surgery and then did a one-year follow-up after the emergency department visit to see whether the patient was still alive. (EurekAlert!)
NOTCHing Up Heart Development Feb 6, 2007
In an accompanying commentary, Leonard Anderson and Gary Gibbons from the Morehouse School of Medicine, Atlanta, discuss the intriguing possibility that defects in the Notch signaling cascade might also be important in adult vascular diseases; something that Epstein and colleagues also suggest. Note: This story has been adapted from a news release issued by Journal of Clinical Investigation. (Science Daily)
ThromboGenics Strengthens its Management Team Feb 5, 2007
Professor Desire Collen, CEO and Chairman of ThromboGenics, said: "I am delighted that we have been able to attract such a group of highly experienced industry professionals to ThromboGenics. I am confident that our strengthened management team will enable us to create further value for our shareholders by advancing the clinical programmes of our most promising drug candidates in back of the eye and vascular disease, and supporting the company in delivering our key corporate objectives." About... (PR Newswire)
Ception takes in $63M in stock sale Jan 31, 2007
is focusing on developing new products to address unmet medical needs in inflammatory, infectious and vascular diseases. The company plans to use the proceeds from the private placement to advance its late-stage biologic anti-inflammatory programs and to further develop its small molecule anti-TNF program. (Philadelphia Business Journal, PA)
AngioDynamics acquisition is given approval Jan 31, 2007
AngioDynamics develops and manufactures medical devices, including catheters and lasers used in the treatment of vascular diseases. It has been expanding its range of products to include those that destroy cancer cells while sparing surrounding tissue. (Albany Times Union)
Fries, GIs, beef bring diabetes to Okinawa Jan 30, 2007
The diet was rich in antioxidants, minerals, omega-3 fatty acids and proteins that helped protect against vascular diseases such as stroke and heart attack, and lowered the risk of cancer, according to a study by Yukio Yamori, director of the International Center for Research on Primary Prevention of Cardiovascular Diseases in Kyoto, Japan. Tofu and Fish. (News on Japan, Japan)
Surgeon performs new heart procedure Jan 29, 2007
Patients not eligible for the new surgery would include those with coronary artery disease or other vascular diseases and those who've had previous cardiac surgery. Patients who have the new procedure can be back to leading an active life in about three weeks rather than two to three months, he said. (Jacksonville Business Journal, FL)
Risk of stroke expected to decrease with new screening guidelines Jan 20, 2007
Screening recommendations are provided for high risk persons in the general population; patients undergoing open heart surgery including coronary artery bypass surgery; patients with peripheral vascular diseases, abdominal aortic aneurysms, and renal artery stenosis; patients after radiotherapy for head and neck malignancies; patients following carotid endarterectomy, or carotid artery stent placement; patients with retinal ischemic syndromes; patients with syncope, dizziness, vertigo or... (SpiritIndia)
Health Roundup: Parasites benefit MS patients Jan 19, 2007
The guidelines are best for high-risk patients, such as those undergoing open-heart surgery or those with peripheral vascular diseases. Researchers report in the Canadian Journal of Psychiatry that previously married mothers have higher rates of mental illness than currently married mothers. (Monsters and Critics.com)
New Anti-angiogenesis Treatment: Combination Therapy Obliterates New Vessel Growth In Tumors And Retinopathy Jan 11, 2007
"Our study shows that combining anti-angiogenic agents that target multiple angiogenic pathways can significantly increase the effectiveness of such a therapeutic approach. Such combination angiostatic therapy provides a whole new range of treatment options for patients with neovascular diseases, where complete inhibition of new blood vessel growth is the desired result." ... In the elderly or diabetic patients, high levels of circulating angiostatics could precipitate stroke or heart attack due... (Science Daily)