Familial Link Found in Rare Childhood Leukemia Aug 10, 2010
Currently, JMML is curable only through hematopoietic stem cell transplantation (HSCT), in which healthy blood stem cells are extracted from a matched donor and intravenously transplanted into the patient. Unfortunately, nearly 50 percent of patients relapse even after receiving HSCT.. (Science Daily)
Intensive Chemotherapy May Be Harmful to Most Older Patients With Acute Myeloid Leukemia Jul 30, 2010
(June 19, 2009) An analysis of previous studies indicates that allogeneic stem cell transplantation (SCT -- stem cells from a compatible donor) is associated with significant overall and relapse-free survival. (Dec. (Science Daily)
Stem Cell Transplantation Successfully Treats Therapy-Resistant Chronic Leukemia, German Study Finds Jul 13, 2010
The German CLL Study Group proved this in a multicentric clinical phase II study led by Professor Dr. Peter Dreger, senior consultant and head of the division of stem cell transplantation at the Department of Internal Medicine V at Heidelberg University Hospital ... High-risk CLL can be controlled in the long term by allogeneic stem cell transplantation ... "Our study is the largest so far for this patient population and proved that allogeneic stem cell transplantation is a promising therapy... (Science Daily)
Parkinson's Transplant Mystery Solved, Researchers Say Jul 2, 2010
"These findings lend much optimism to new human trials testing the safety and efficiency of fetal or stem cell transplantation in Parkinson's patients," said study author Dr. Marios Politis, a clinical scientist at Imperial College London, whose report is published in the June 30 issue of Science Translational Medicine. In the early 1990s, scientists were excited about promising results of clinical trials using fetal cell transplants to treat Parkinson's disease. (MEDLINEplus)
Leukemia society funding Onconova research Jun 2, 2010
Currently, the only potential cure is stem cell transplantation from a donor. However, patients who have MDS may not be candidates for this option due to their advanced age and underlying bone marrow deficit. (Philadelphia Business Journal, PA)
Clocks in the Americas and the Caribbean Islands Now Ticking in Unison May 31, 2010
27, 2010) An examination of the world-wide use of hematopoietic stem cell transplantation (HSCT), which involves transplantation of blood stem cells derived from the bone marrow or blood, finds that there are. (Mar. (Science Daily)
African-Americans and women are less likely to undergo bone marrow transplantation May 24, 2010
Bone marrow transplantation, or hematopoietic stem cell transplantation (HCT), is a relatively new treatment that is costly and generally requires lengthy intensive hospitalization and prolonged follow-up care ... Article: "Access to hematopoietic stem cell transplantation: effect of race and gender." Thomas V. Joshua, J. Douglas Rizzo, Mei-Jie Zhang, Parameswaran N. Hari, Seira Kurian, Marcelo Pasquini, Navneet S. Majhail, Stephanie J. Lee, and Mary M. Horowitz. (EurekAlert!)
Synthetic Peptide May Enhance Lung Transplantation Apr 14, 2010
15, 2009) The majority of patients with type 1 diabetes who underwent a certain type of stem cell transplantation became insulin free, several for more than three years, with good glycemic control, and also. (Apr. (Science Daily)
M. D. Anderson develops tool to measure severity of chronic graft-vs.-host disease symptoms Mar 2, 2010
ORLANDO, FL - Researchers from The University of Texas M. D. Anderson Cancer Center have developed a new assessment tool to measure the severity of symptoms that can complicate stem cell transplantation ... cGVHD - a chronic disease that requires the close management of symptoms for an indefinite period of time - usually develops more than three months after allogeneic hematopoietic stem cell transplantation (alloHSCT) ... "The survey will help open the conversation about chronic... (EurekAlert!)
Fetal Surgery Continues to Advance Feb 22, 2010
In-utero hematopoietic stem cell transplantation (IUHCT) focuses on stem cells that develop into all the types of cells found in the blood. The keystone of this approach is the fetal immune system's unique tolerance of transplanted cells. (Science Daily)
Tonya N. Cano, 42, dies after battle with cancer Feb 16, 2010
Muzaffar Qazibash, M.D., an associate professor in M.D. Anderson s Department of Stem Cell Transplantation and Cellular Therapy, has developed a vaccine for patients with recurring Acute Myeloid Leukemia (AML). Trials for the vaccine began in 2000. (Alpine Avalanche, TX)
First FDA-Approved Stem Cell Trial in Pediatric Cerebral Palsy Feb 12, 2010
"Autologous stem cell transplantation, in which the transplant recipient is also the donor, is the safest form of stem cell transplantation because it carries virtually no threat of immune system rejection," he said. While no controlled clinical trials have been conducted to date, previous studies have shown marked improvement in children with cerebral palsy about three months after an initial infusion of cord blood. (Science Daily)
Discovery May Expand Availability of Bone Marrow Transplants by Stopping Fatal Complications Feb 9, 2010
Lappas et al. Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation. Journal of Leukocyte Biology, 2010; 87 (2): 345 DOI. (Science Daily)
Stem Cell Therapy closes Histostem merger Feb 2, 2010
Stem Cell Therapy, which plans to change its name to , focuses on treating patients with stem cell transplantation therapy and on providing supplies of biological solutions containing new lines of stem cell products. Most Read Stories. (Tampa Bay Business Journal, FL)
Researchers find leukemia cells metabolize fat to avoid cell death Jan 28, 2010
D., professor in M. D. Anderson's Department of Stem Cell Transplantation and Cellular Therapy ... "Our findings suggest that mitochondrial function and resistance to apoptosis in leukemia cells are intimately linked with the entry of fatty acids into mitochondria," said first author Ismael Samudio, M.D., a fellow in Stem Cell Transplantation and Cellular Therapy ... D., and Seshargiri Duvvuri of M. D. Anderson's Department of Stem Cell Transplantation and Cellular Therapy; Romain Harmancey, Ph.... (EurekAlert!)
Women With Breast Cancer May Benefit from Autologous Stem Cell Transplantation Jan 14, 2010
13, 2010) Compared to conventional chemotherapy, autologous stem cell transplantation can extend "event-free survival" for breast cancer patients ... However, there are indications that this type of stem cell transplantation can more frequently give rise to severe complications affecting almost all organ systems ... In autologous stem cell transplantation (autologous SCT), the patient's own (autologous) haematopoietic stem cells are removed at a suitable time during treatment and re-implanted... (Science Daily)
Stem Cell brings on international exec Jan 13, 2010
Stem Cell Therapy International (OTBCC: SCII), headquartered in Tampa, focuses on treating patients with stem cell transplantation therapy as well as providing the supplies of biological solutions containing new lines of stem cell products. Most Read Stories. (Tampa Bay Business Journal, FL)
Drug that modifies gene activity could help some older leukemia patients Jan 13, 2010
By comparison to standard chemotherapy and stem cell transplantation, the treatment was considered a low-intensity treatment and was more tolerable for elderly patients, especially those with accompanying medical problems. In 24 percent of the study participants, blood counts and bone marrow returned to normal, which is considered a complete response. (EurekAlert!)
Bone Marrow Transplantation Jan 10, 2010
Volume 44, No 12December (2) 2009ISSN: 0268-3369EISSN: 1476-5365. 2008 impact factor 3. (Nature News Service)
Stem Cells May Improve Heart Bypass Results Jan 10, 2010
TUESDAY, Nov. 17 (HealthDay News) -- Patients who received bone marrow stem cell transplants during coronary bypass surgery (CABG) experienced "excellent long-term safety and survival," say German researchers, who also noted the first promising results for stem cell transplantation during mitral valve repair. The study included 35 patients who received CD 133+ bone marrow stem cell transplantation during CABG, 20 patients who received only CABG surgery and 10 patients who received stem cell... (MEDLINEplus)
