Parion lands $25M drug development deal with Kainos Medicines Oct 29, 2008
Sjogren's syndrome patients are seeking effective relief of their dry mouth, Parion CEO M. Ross Johnson said in a written statement. By combining the talents and expertise of two proven development teams, we believe we can accelerate the clinical development of P-552 to effectively address this unmet need. (Raleigh Triangle Business Journal, NC)
Green tea may delay type-1 diabetes Oct 25, 2008
Researchers were testing EGCG, green tea's predominant anti-oxidant, on a lab mouse with type-1 diabetes and primary Sjogren's syndrome, which damages moisture-producing glands, causing dry mouth and eyes. "Our study focused on Sjogren's syndrome, so learning that EGCG also can prevent and delay insulin-dependent type 1 diabetes was a big surprise," said Stephen Hsu, molecular cell biologist at the School of Dentistry, Medical College of Georgia (MCG) ... In the mouse, EGCG reduced the severity... (India Times, India -- Health/Science)
Malignant Lymphoma and Autoimmune D... Sep 8, 2008
Several autoimmune conditions, such as Sjogren's syndrome, thyroiditis, and rheumatoid arthritis, have consistently been linked to malignant or non-Hodgkin's lymphoma. In recent years, the worldwide incidence of malignant lymphoma has increased dramatically, and the number of autoimmune diseases linked to non-Hodgkin s lymphoma (NHL) has also increased. (Suite101.com)
She's so happy she could cry Aug 16, 2008
Mrs Jamieson, from Clear Island Waters in Queensland, has Sjogren's Syndrome, in which the body's immune cells attack the exocrine system that produces tears and saliva ... An ophthalmologist at the Sydney Eye Hospital, Dr John Males, said dry eyes from Sjogren's Syndrome were notoriously challenging to treat. (Sydney Morning Herald -- Australia)
TorreyPines Therapeutics Announces Management Change and Second Quarter 2008 Financial Results Aug 9, 2008
"We are currently preparing for our end of Phase II meeting with the FDA on September 29th during which we will discuss our proposed Phase III migraine program for tezampanel. In addition, we are continuing to advance NGX426, the oral version of tezampanel, having initiated a Phase I clinical trial to evaluate its analgesic effect. We anticipate announcing results from this Phase I trial by the end of the year, as well as announcing results from an ongoing Phase II clinical trial of our lead... (PR Newswire)
Autoimmune diseases on the rise in Ghana Jun 20, 2008
Dr Michael F. Ofori, Immunologist, Nogochi Memorial Institute for Medical Research, said though the availability of data on the prevalence and incidence was lacking in developing countries, physicians and scientists had so far identified over 80 different autoimmune diseases including less known ones like autoimmune hepatitis, Sjogren's syndrome and pemphigus. He said economically, majority of individuals with the diseases experienced poor quality of life since the cost of health care was high. (Ghana Web, Ghana)
Final edition: Lake County Leader's Paul Fugleberg retires after 55 years in the newspaper business Jun 1, 2008
He lost Mary Lou, too, to a rare autoimmune disorder called Sjogren's Syndrome, in 1996. She had it over 15 years, Fugleberg says. (Missoulian, MT)
Sjogren's Syndrome--UR Can Help May 10, 2008
Melanie Young, 53, of Sodus was first diagnosed with Sjogren's syndrome eight years ago ... Experts at the U of R Eye Institute will hold a free health talk May 12 about Sjogren's syndrome at the Pittsford Community Library, located at 24 State Street in Pittsford. (WOKR13 Rochester)
LETTER: Arthritis Walk will help fight Sjogren's Syndrome May 3, 2008
TODAY'S HEADLINES SPECIAL SECTION ONLINE POLL. What will you do with your tax rebate stimulus check. (Mattoon Journal-Gazette, IL)
A Reunion to Mark a Jubilee May 2, 2008
" Although Sister Jane has kept up on Washington news the last six decades through West, she hasn't made many trips home. She was in town, though, for her WHS 50-year reunion. Sister Jane's official jubilee celebration will be held Saturday, May 17, at the mother house in St. Louis. The event will include a Mass and reception for Sisters celebrating their 50-, 60- and 70-year jubilees. Advocate for Sjogren's Syndrome In addition to her work as a LCSW, Sister Jane also volunteers as an advocate... (Missourian Publishing, MO)
Local mom chairs lupus walk, set for May 11 Apr 11, 2008
"They have offered help, and are giving free parking for all walkers. Walkers can park in the open air lot behind the West Hartford Town Hall, which can accomodate 500 vehicles, and if that fills up, participants can park in one of the parking garages and have their tickets validated. There will be two walks; the short one goes just around Blue Back Square, which is 1.2 miles; the longer walk starts at BBS and heads up the Boulevard, offering three options for intersecting with Farmington... (Newington Town Crier, CT)
A history of being innovative and fun Mar 3, 2008
It was known that patients with type 1 diabetes also have high rates of Sjogren's syndrome - an autoimmune disorder that attacks the glands that produce tears and saliva - and conditions associated with hearing loss and tongue abnormalities. Before, researchers were convinced that the immune system's misfiring was causing these collateral problems. (Boston Globe)
Fatty Acids Beneficial In Treatment For Dry Eye Syndrome Feb 16, 2008
This research was supported by grants from Johnson and Johnson Vision Care, Inc., and the Sjogren's Syndrome Foundation. Adapted from materials provided by , via , a service of AAAS.. (Science Daily)
Clinic to hold health talk on arthritis Jan 11, 2008
Fibromyalgia can accompany an inflammatory rheumatic disease, such as rheumatoid arthritis, lupus or Sjogren's syndrome, Ziegenbein explained. Fibromyalgia also seems to run in families, so a gene may be at least partly responsible for the condition. (Forest Republican, WI)
Lantibio and TRB Chemedica Announce Licensing Agreement with Alcon for US Development and Marketing of Dry Eye Drug Nov 6, 2007
In a related affliction, Sjogren's syndrome patients suffer dry eyes and dry mouth. Sjogren's syndrome is one of the most prevalent autoimmune disorders, striking as many as 3 million Americans ... More than 90 percent of Sjogren's syndrome sufferers are women and while prevalence increases with age, the average age of onset is in the late 40's. (PR Newswire)
North San Diego County Community News Briefs: 'Candid Conversations' class offered Oct 4, 2007
Sjogren's syndrome group to meet. LA JOLLA -- The San Diego and Imperial Counties chapter of the Sjogren's Syndrome Foundation will meet from 9:30 to 11:30 Oct. 13 in the Coral Room at Thornton Hospital, 9300 Campus Point Drive ... The featured presentations are "Overview of Sjogren's Syndrome Manifestations" by Dr. Steven Carsons and "Impact of Stress in Autoimmune Diseases" by Dr. Esther M. Sternberg. (North County Times)
Chairside: When A Dry Mouth Is a Health Problem Aug 22, 2007
And sometimes dry mouth is a symptom in a more serious condition, such as diabetes or Sjogren's syndrome, an autoimmune dysfunction in which the moisture glands throughout the body under-produce. Don't ignore it You shouldn't just dismiss dry mouth as an uncomfortable nuisance. (Hillsdale Independent, NY)
Partnership worth up to $156M boosts Durham pharma Aug 17, 2007
Parion's lead drug candidate, P-552, is in phase I/II trials for the treatment of cystic fibrosis and Sjogren's syndrome, a drying of the mouth that can lead to various problems throughout the body. Boucher said the company is still weighing its options with that drug, including whether to find a partner for it and whether to hire more than the handful of employees it now has to develop the treatment. (Triangle Business Journal)
Genetic Mutations Linked To Lupus Aug 2, 2007
The current research also links it to Sjogren's syndrome, a form of lupus. The diseases are all autoimmuine diseases, which means that the body makes antibodies against itself. (Science Daily)
North San Diego County Community News Briefs: Open mike event for singers on tap May 31, 2007
Sjogren's syndrome group to meet. LA MESA -- The San Diego and Imperial Counties Chapter of the Sjogren's Syndrome Foundation will meet for a "Sharing and Caring" luncheon at noon June 9 at Coco's restaurant, 5550 Lake Murray Blvd. For information and reservations, call Dona Frosio at (619) 303-9004. (North County Times)
The kindness of strangers May 3, 2007
Patty had always suffered from terrible allergies, and in her 60s she was diagnosed with Sjogren's Syndrome, an autoimmune disease, and with rheumatoid arthritis. However, she never complained, her daughter said. (Towson Times, MD)
Green Tea May Ease Rheumatoid Arthritis May 1, 2007
Hsu studied EGCG's effect in helping to inhibit an autoimmune disorder known as Sjogren's syndrome, in which the salivary glands are affected, and in lupus, in which the skin is affected. The new research by Ahmed is one of the first to focus on rheumatoid arthritis and green tea, Hsu said. (Forbes)
A Revolution In The Monitoring Of Unborn Babies Apr 27, 2007
The device will be especially helpful in monitoring fetuses whose mothers have medical conditions like diabetes, autoimmune conditions such as systemic lupus erythematosus and Sjogren's syndrome and obstetric cholestasis. It will also be useful in monitoring fetuses identified as growing poorly or where it is suspected that the placenta is unhealthy and hence the fetus may become compromised due to lack of oxygen. (Science Daily)
Green Tea May Help With Disease Apr 24, 2007
Researchers tested mice that had Sjogren's syndrome, a condition that damages the glands that produce tears and saliva. They found mice given green tea extract had less salivary gland damage and inflammation when compared with mice given water. (KRNV.com, NV)
Green tea may help prevent autoimmune diseases Apr 22, 2007
In the new study, researchers led by Stephen Hsu, from the Medical College of Georgia, School of Dentistry, studied an animal model for type I diabetes and primary Sjogren's syndrome, which damages the glands that produce tears and saliva ... "Since it is an autoimmune disease, Sjogren's syndrome causes the body to attack itself and produce extra antibodies that mistakenly target the salivary and lacrimal glands," Hsu said ... There is no cure or prevention for Sjogren's syndrome. (PakTribune.com)
Restoring lost taste can be difficult Apr 18, 2007
Many things, including Sjogren's syndrome, bring on mouth dryness, and countering a dry mouth can perk up taste. Changing the way you eat also helps. (Herald-Tribune)
Lichen Planus Apr 6, 2007
A Common Skin Rash in Autoimmune Disorders. It is also reported to occur in infections. (Suite101.com)
North San Diego County Community News Briefs: Easter Egg Hunt set for Sunday Apr 6, 2007
Sjogren's syndrome group to meet. LA JOLLA -- The San Diego and Imperial Counties chapter of the Sjogren's Syndrome Foundation will meet at 9:30 a.m. April 14 in the Coral Room at Thornton Hospital, 9300 Campus Point Drive ... Dr. Kentaro Yamada of the Eye Treatment Center in San Diego will present "Update on Dry Eye." Sjogren's syndrome is an autoimmune disorder. (North County Times)
Saliva Tests Making Their Way to Routine Care Mar 22, 2007
Based on their detective work, Wong's group announced that their research has already uncovered indicators pointing the way toward diagnosing both oral cancer and an autoimmune illness called Sjogren's syndrome ... Similarly, a small subset of proteins and mRNAs appears to serve as markers for Sjogren's syndrome ... An even larger patient pool now combats Sjogren's syndrome, a disorder in which white blood cells attack moisture-producing glands, causing dry eyes and dry mouth. (Health-Finder)
What's in there? Mar 22, 2007
Many medications can cause a dry mouth, Scott said, but there are also afflictions that are characterized by dry mouth, such as Sjogren's syndrome, an autoimmune disease in which the body's immune system mistakenly attacks its own moisture-producing glands. Allergies. (The Daily Reflector)
Vasculitis Update Mar 21, 2007
In addition, many other autoimmune conditions such as rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus (SLE) are accompanied by vasculitis. Vasculitis can also occur in other conditions such as non-Hodgkin s lymphoma, Hodgkin s disease, myelogenous leukemia, adenocarcinoma, and carcinoma of the bronchus. (Suite101.com)
Benefits of a Gluten-Free Diet Feb 20, 2007
Conditions associated with gluten allergies include: dermatitis herpetiformis, IgA deficiency, Type I diabetes, autoimmune thyroid disease, Sjogren's syndrome, microscopic colitis, rheumatoid arthritis, Down's syndrome, and IgA nephropathy. The Living Without article "All in your head" lists the following as conditions possibly associated with gluten: congenital heart disease, recurrent pericarditis (inflammation of the sack around the heart), lung disease, inflammatory bowel disease, autoimmune... (Suite101.com)
In Sjogren's, body initiatesattack on saliva, tear glands Jan 26, 2007
DEAR DR. DONOHUE: My granddaughter, 20, has Sjogren's syndrome and rheumatoid arthritis ... Your granddaughter has a compassionate and powerful friend in the Sjogren's Syndrome Foundation. (The Standard-Times, MA)
The last goodbye Jan 26, 2007
He has Sjogren's syndrome, which dries the glands in the eyes and mouth, making swallowing difficult. He keeps an oxygen bottle by his bed as he says his occasional sleep apnea, which stops his breathing, could kill him. (Sydney Morning Herald -- World)
Autoimmune Pancreatitis Jan 7, 2007
Inflammatory Pancreatic Disease. The pancreas is an endocrine gland situated in the abdominal cavity that helps regulate blood glucose levels and assists with the digestion of fatty lipids. (Suite101.com)