Biotech startup gets $5.5M Jun 30, 2008
Often the diagnosis comes after the infection has already invaded the bloodstream, a process known as "sepsis." About 750,000 cases of severe sepsis occur every year in the U.S., with 29 percent of them resulting in death. Once sepsis occurs, treatment is expensive, costing on average $22,000 per case, Esch said ... "Once you get sepsis, it's very, very dangerous," Esch said. (New Mexico Business Weekly, NM)
More of this story Jun 26, 2008
Patients who require daily monitoring because of multi-system failure, kidney disease, long-term IV therapy, infectious diseases, cardiovascular disease, congestive heart failure, nutritional impairment, cancer and sepsis can now be served locally. The hospital will also care for those who are dependent on ventilators, and it will help wean patients off of them as needed. (Searcy Daily Citizen, AR)
Spectral announces continuing support for the combination of EAA(TM) and anti-endotoxin therapeutics Jun 26, 2008
- Data to be presented at International Shock Congress by sepsis thought leaders - TORONTO, June 26 /CNW/ - Spectral Diagnostics Inc. (TSX: SDI) today announced the presentation of data that demonstrates the combined clinical effectiveness of its Endotoxin Activity Assay (EAA(TM)), the only FDA cleared diagnostic for the measurement of endotoxin, to identify patients with elevated endotoxin levels and to guide endotoxin reducing strategies, such as Toray Medical's therapeutic column,... (Canada Newswire)
Another husband's death re-examined Jun 25, 2008
He died in October, and authorities in Augusta are investigating whether his death -- officially listed as listed as sepsis, bacterial infection of the body's blood and tissues -- might have another cause, such as arsenic poisoning. Reader Comments Note: Comments are not edited and don't represent the views of The Augusta Chronicle. (The Augusta Chronicle)
Researchers To Simulate And Analyze Brain, Immune System Activity And Apply Math To Medical Problems Jun 25, 2008
The immune system models will plot the various chemical and physical changes that occur as the body battles influenza, inflammation, sepsis and necrosis, and wounds. Ultimately, Rubin explained, the researchers want to pinpoint the origin of such conditions as multiple organ dysfunction syndrome (multiple organ failure), a potentially deadly, uncontrollable inflammation that usually strikes ailing patients with compromised immune systems. (Science Daily)
Cops re-examine 43-year old death Jun 25, 2008
are investigating whether his death officially listed as sepsis, bacterial infection of the body's blood and tissues might have another cause, such as arsenic poisoning. Williams said he's still working to uncover as much as he can about Neumar's first two husbands, both of whom he said were from Ohio. (Florida Keys Keynoter)
Cops Investigate Woman With 5 Dead Husbands Jun 18, 2008
are investigating whether his death officially listed as listed as sepsis, bacterial infection of the body's blood and tissues might have another cause, such as arsenic poisoning. Williams said Neumar would wedge herself between family members and her victims to isolate them. (Fox News)
Doctor cites 'ethical turmoil' in decision not to treat terminally ... Jun 18, 2008
"This individual has had a slow declining level of health, and has what I would consider an insurmountable problem with wound infections and resultant sepsis and renal failure. The patient now had required an escalation in medical support to sustain life, which I felt would only increase suffering and provide no benefit.". He wrote that he was informed that his actions could lead to further legal action if withholding treatment results in Golubchuk's death. (Canada.com)
N.C. police may have been warned of murder Jun 17, 2008
are investigating whether his death officially listed as listed as sepsis, bacterial infection of the body's blood and tissues might have another cause, such as arsenic poisoning. Williams said hes still working to uncover as much as he can about Neumars first two husbands, both of whom he said were from Ohio. (MSNBC -- Crime)
Sole Survivors - Germs And Shoes Jun 17, 2008
Serratia ficaria causing gallbladder empyemas and sepsis as well as biliary infections. Gerba stated that "The common occurrence (96%) of coliform and E. coli bacteria on the outside of the shoes indicates frequent contact with fecal material, which most likely originates from floors in public restrooms or contact with animal fecal material outdoors". (Suite101.com)
Suspect's husbands are dead Jun 14, 2008
His cause of death was listed as sepsis an illness caused by a bacterial infection of the body's blood and tissues and his body was cremated shortly after his death. Peebles said investigators would test the remains to see if there "were any other factors that contributed to his death," including whether he was poisoned by arsenic, which can cause sepsis-like symptoms. (Atlanta Journal-Constitution)
Fungal exposure and gardening Jun 14, 2008
His condition worsened, and he showed signs of kidney distress and sepsis (high heart rate, low blood pressure and fever in response to infection throughout the body). The clinicians found that a fungus called Aspergillus fumigatus grew from the mans saliva samples. (NHS Choices)
Man died after inhaling spores of garden fungus Jun 13, 2008
Tests showed that the man, who was previously of good health, was suffering from "overwhelming sepsis", a condition in which the immune system over-compensates while under attack, leading to kidney problems, low blood pressure, and a fast heart rate. After being referred to a specialist regional centre and put on a heart-lung machine, the man's condition continued to worsen, leading to kidney failure and eventual death. (Independent)
Health Experts Call on Global Leaders to Ensure Access to Life-Saving Pneumococcal Vaccines Jun 10, 2008
A bacterial infection that causes pneumonia, meningitis, sepsis and other life-threatening ailments, pneumococcal disease kills 1. 6 million people -- including more than 800,000 children under age five -- each year. (Canada Newswire)
Manila hospital unit closed after 25 babies die: report Jun 7, 2008
Local authorities ordered the Ospital ng Makati to close the unit after 45 babies contacted neonatal sepsis last month ... The Inquirer said 45 cases of neonatal sepsis, a blood infection contracted by infants less than 90 days old, were reported at the hospital in May out of 273 deliveries ... "Neonatal sepsis could also be caused by unsanitary hospital conditions," he added. (Yahoo! Asia News)
North Carolina police await suspect's arrival Jun 4, 2008
Family members have said his cause of death was sepsis, an infection of the bloodstream or tissues, but investigators believe some of his symptoms could be indicative of arsenic poisoning. Mr. Neumar's ashes have been sent to the Georgia Bureau of Investigation's Crime Lab in Atlanta and investigators are awaiting the results of the test. (The Augusta Chronicle)
Lack Of Dental Care May Have Life-threatening Implications Jun 3, 2008
The authors recommend that access to routine and emergency dental care be reviewed and formal and robust systems of referral established to ensure that GPs can be confident that patients presenting to them with acute dental sepsis will receive appropriate dental treatment. Speaking about the findings, Dr Thomas said: Dental abscess is a serious problem and can be life threatening. (Science Daily)
Final Results of the CellCept(R) Spare the Nephron (STN) Study Show Maintenance Therapy is Associated with Improved Renal Function Jun 2, 2008
-- Oversuppression of the immune system can also increase susceptibility to infection, including opportunistic infections, and sepsis. -- Cases of progressive multifocal leukoencephalopathy (PML), sometimes fatal, have been reported in patients treated with CellCept. (PR Newswire)
Large study identifies most costly adverse events in children's hospitals Jun 2, 2008
Overall, the most frequent adverse events in hospitalized children were infection due to medical care, respiratory failure following surgery and postoperative sepsis (an infection in the bloodstream) ... 5 days for postoperative sepsis ... For instance, focusing quality improvement efforts on reducing postoperative sepsis and infection due to medical care could create large cost savings and reduction in length of hospitalization. (EurekAlert!)
Police search woman's home May 31, 2008
Family members said his cause of death was listed as sepsis -- an illness often afflicting the elderly that is caused by bacterial, fungal, viral or parasitic infections of the bloodstream or tissues ... Both arsenic and sepsis can cause total body organ failure, but the progression of symptoms to that point would differ, Joshua Schier, a medical toxicologist with the Centers for Disease Control and Prevention, said via a spokeswoman Friday ... Exposure to arsenic would involve swallowing the... (The Augusta Chronicle)
Suspect to return to North Carolina May 29, 2008
Family members said Mr. Neumar died of sepsis, an illness that is caused by bacterial, fungal, viral or parasitic infections of the bloodstream or tissues. Secondary causes included ischemic bowel, or an injury to the large intestine caused by inadequate blood supply, and ileus, a disruption of the digestive system. (The Augusta Chronicle)
Death of husband interests officers May 28, 2008
Family members said his cause of death was listed as sepsis -- an illness often afflicting the elderly, caused by bacterial, fungal, viral or parasitic infections of the bloodstream or tissues. Secondary causes were ischemic bowel, defined as injury to the large intestine caused by inadequate blood supply, and ileus, a disruption of the digestive system. (The Augusta Chronicle)
Hospitals in north rated by coalition May 26, 2008
Samaritan also was found to be "at the state average" in risk of collapsed lung, infections due to medical care and postoperative sepsis ... Lewis County General Hospital received average ratings in congestive heart failure mortality, pneumonia mortality and risks of collapsed lung, infections due to medical care and postoperative sepsis ... It also received average ratings for risk of collapsed lung and risk of postoperative sepsis. (WatertownDailyTimes.com)
Columbia Memorial Hospital scores 'average' on state report card May 25, 2008
Columbia Memorial stayed consistent, with average ratings for risk of collapsed lung, infections due to medical care and post-operative sepsis ... Regarding risk of collapsed lung, infections due to medical care and post-operative sepsis, North Dutchess received at the state average ratings in all three categories. (Catskill Daily Mail, NY)
Major 'Missed' Biochemical Pathway Emerges As Important In Virtually All Cells May 24, 2008
"This action has a broad-based effect, frankly, and probably happens in virtually all cells and across all protein classes. Nitric oxide is implicated in many disease processes. Sepsis, asthma, cystic fibrosis, Parkinson's disease, heart failure, malignant hyperthermia -- all of these diseases are linked to aberrant nitric-oxide-based signaling.". An important factor that previously wasn't appreciated, he said, is that the target of nitric oxide in disease is different in every case. (Science Daily)
TechCoire to host LifeScienceFest in Davis May 23, 2008
of Las Vegas, which is developing tests for sepsis. of Carlsbad, a mid-stage diagnostic test developer. (Sacramento Business Journal, CA)
Educational Drive Cut Death Rate from Sepsis May 22, 2008
TUESDAY, May 20 (HealthDay News) -- A national education program in Spain to promote appropriate care for severe sepsis (bloodstream infection) and septic shock led to improved guideline adherence and a lower rate of sepsis deaths in hospitals, a new study says. Severe sepsis accounts for one in five admissions to intensive care units and is a leading cause of death in non-cardiac ICUs, the study authors noted ... In the United States, patients with severe sepsis have a death rate of 28. (MEDLINEplus)
Dialysis more often doesn't help patients May 21, 2008
It affects more than 35 percent of critically ill hospitalized patients and is often linked with severe sepsis, a systemic bodily infection that can lead to organ failure. Mortality rates for hospitalized patients suffering from chronic kidney disease can range from 50 to 80 percent. (The Star-Ledger - NJ.com)
Liver Molecule Found To Reduce Mortality During Sepsis May 20, 2008
The study, published online in advance of publication in the June issue of Nature Medicine, shows that the Ashwell receptor plays an essential role in reducing coagulation abnormalities during infection and sepsis, significantly improving the probability of survival. Sepsis, a life-threatening complication of bacterial infection in the blood, remains a major cause of death worldwide, according to the study's principal investigator, Jamey Marth, Ph ... One of the major factors contributing to... (Science Daily)
Former firefighter convicted of elder abuse murder of mom May 17, 2008
She died of sepsis of the blood a few hours later. Domio faces up to life in prison without the possibility of parole. (Fresno Bee -- State)
CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients May 17, 2008
Severe ulceration may cause breaks in the mucosa, which can then become susceptible to oral opportunistic infections, possibly resulting in bacteremia (the presence of bacteria in the blood), sepsis (the presence of pathogenic microorganisms in the blood) or other potentially fatal complications. The economic impact of mucositis can be significant, as the need for prolonged hospital stays, nutritional therapy and treatments for pain and infection can drive up the costs of therapy. (EurekAlert!)
Health Canada approves "Personalized medicine" for metastatic colorectal cancer May 15, 2008
Severe dermatologic toxicities were complicated by infection, including sepsis, in rare cases leading to death, and local abscesses requiring incision and drainage. It is recommended that patients wear sunscreen and a hat and limit sun exposure while receiving Vectibix(TM) as sunlight can exacerbate any skin reactions that may occur. (Canada Newswire)
Spectral announces first quarter 2008 results May 14, 2008
About Spectral Diagnostics Spectral is a leader in the battle against sepsis ... With the growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being developed for this indication, Spectral is well-positioned to drive the adoption of the EAA(TM), which can be used to identify patients, enable therapeutics and monitor treatment. (Canada Newswire)
Group B Strep Down Among Newborns, Up Among Adults May 13, 2008
Group B strep is the leading cause of sepsis and meningitis in the first week of life. Prevention strategies put in place during the 1970s have helped quell the condition, called early-onset disease. (MEDLINEplus)
As Burma's junta counts its fake votes, photos show the reality May 12, 2008
He said sepsis, a infection in the blood that causes organ failure, was commonplace. "These are injuries we have never seen before," he said. (Sydney Morning Herald -- World)
RPT-Slow Myanmar aid raises health risks for survivors May 11, 2008
He said sepsis, a rampant infection of the bloodstream that causes organ failure, was widespread two days after the former Burma's worst natural disaster in recent memory. "These are injuries we have never seen before," he said in Myaung Mya, 50 km (30 miles) north of Labutta where 80 percent of buildings were damaged or destroyed, including the hospital which had its roof ripped away. (AlertNet)
Incidence Of Group B Strep Has Decreased Among Newborns, But Has Increased Among Adults May 8, 2008
In the 1970s, group B streptococcus emerged as the leading cause of sepsis and meningitis in the first week of life ... 7, 2005) The problem of increasing antibiotic resistance in cases of Streptococcus pneumoniae, a major cause of pneumonia, meningitis and sepsis, was dramatically reversed following the licensing and use of a. (Science Daily)
Insulin and Pentastarch for Severe Sepsis May 8, 2008
10 issue)1 report that the Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP) study established "that intensive insulin therapy has no measurable, consistent benefit in critically ill patients" in a medical intensive care unit (ICU). This interpretation appears too conclusive, since the Supplementary Appendix of the article (available with the full text of the article at www. (New England Journal of Medicine)
Corticosteroids for Septic Shock May 8, 2008
However, it is disturbing that of the 357 study patients with culture-positive sepsis, 86 (24%) were considered not to have received appropriate antimicrobial therapy ... Antimicrobial agents remain the cornerstone of therapy for sepsis. (New England Journal of Medicine)
New Discovery On Role Of Vital Protein That Fights Meningitis May 7, 2008
"I hypothesised that the importance of Properdin extends beyond this particular infectious disease, and that indeed it is an important player in health generally, and that its importance becomes apparent in conditions involving both acute and chronic states of inflammation. Now two of Dr Stover's papers, published in the Journal of Immunology, demonstrate that Properdin plays a significant role in the survival of conditions relating to surgical perforation of the gut and activation of the immune... (Science Daily)
Bureaucracy Hampers an E. Coli Weapon May 7, 2008
It is used today to perform a wide variety of genetic tests, as well as to detect HIV, sepsis, and urinary tract infections. GeneSystems has built on the basic PCR process by marrying it with automation, so that its use is no longer limited to research or specialized tests that target a single agent. (BusinessWeek)
'Menveo improves meningitis immunity' May 7, 2008
Infection with any of the four serogroups tested can cause bacterial meningitis, an infection of the membrane around the brain and spinal cord, or sepsis, a serious blood infection. Meningococcal disease -- characterised by fever, headache and a stiff neck -- can cause seizures, brain damage, memory loss and death in otherwise healthy people in less than 48 hours. (India Times, India -- Health/Science)
Spectral and Toray expand collaboration to include new geographic territories May 5, 2008
About Toraymyxin Toraymyxin, a blood purification device, absorbs the bacterial toxin (endotoxin) that causes sepsis and septic shock using a special fiber ... About Spectral Diagnostics Spectral is a leader in the battle against sepsis ... With the growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being developed for this indication, Spectral is well-positioned to drive the adoption of the EAA(TM), which can be used to identify patients, enable... (Canada Newswire)
Principles of Critical Care May 3, 2008
A patient who requires hemodynamic support may have conditions involving life-threatening bleeding, an infection associated with a large drop in blood pressure (sepsis), or an unstable heart. Intravenous fluids, or blood if there is hemorrhage, are one option to correct low blood pressure. (Suite101.com)
Newswatch, Police/Fire Apr 23, 2008
He was immediately admitted to Wilcox Hospital, where doctors found Hironaka had also suffered a small heart attack and had sepsis. He was removed to another care home and recovered from his injuries, but died several months later of respiratory failure, state officials said. (Honolulu Star-Bulletin)
Family to march for awareness Apr 20, 2008
All in all, she endured a laundry list of diseases and disorders that rack most preemies: Respiratory Distress Syndrome; Chronic Lung Disease; Retinopathy of Prematurity; Sepsis and the list goes on. The tiny girl stayed hooked to hoses and machines in the hospital for 108 days. (Suffolk News Herald, VA)
Effects of resuscitation with crystalloid fluids on cardiac function in patients with severe sepsis Apr 18, 2008
The use of hypertonic crystalloid solutions, including sodium chloride and bicarbonate, for treating severe sepsis has been much debated in previous investigations. We have investigated the effects of three crystalloid solutions on fluid resuscitation in severe sepsis patients with hypotension ... Ninety-four severe sepsis patients with hypotension were randomly assigned to three groups. (BioMed Central)
Medicals Errors Cost the US Lives and Billions of Dollars Apr 11, 2008
The analysis found that out of all patients, 3 percent experienced medical errors, such as anesthesia complications, bed sores, failure to rescue (respiratory failure, pulmonary embolism or deep vein thrombosis, sepsis and abdominal wounds that split open after surgery), selected infections due to medical care, as well as many post-operative events. This percentage comes out to about 1. (eFluxMedia)
Millennium Announces VELCADE(R) (Bortezomib) for Injection First-Quarter 2008 U.S. Net Sales Apr 10, 2008
In total, 2% of the patients died and the cause of death was considered by the investigator to be possibly related to study drug: including reports of cardiac arrest, congestive heart failure, respiratory failure, renal failure, pneumonia and sepsis. This integrated analysis does not include the Phase 3, VELCADE plus DOXIL study. (PR Newswire)
Spectral's EAA(TM) to be used in Phase III study for a sepsis anti-endotoxin therapy Apr 9, 2008
TORONTO, April 9 /CNW/ - Spectral Diagnostics Inc. (TSX: SDI) today announced that its Endotoxin Activity Assay (EAA(TM)), an FDA cleared diagnostic for risk of sepsis, will be used to measure endotoxin levels during the enrolment of patients in a Phase III sub study, part of a multinational clinical trial evaluating the safety and effectiveness of a treatment for severe sepsis ... The Phase III sub study will explore the utility of partnering a reliable measurement of endotoxin, the EAA(TM),... (Canada Newswire)
Before Code Blue: Who's minding the patient? Apr 9, 2008
Four important post-operative indicators got worse: respiratory failure, pulmonary embolism or deep vein thrombosis, sepsis and abdominal wounds that split open after surgery. Overall, the rate of patient safety problems has remained steady at about 3 percent of Medicare hospitalizations, the report indicated. (MSNBC -- Terrorism)
In Three Years, $8.8B Goes To Medical Errors Apr 9, 2008
Post-operative sepsis. Bed sores, failure to rescue and respiratory failure made up 63. (Click2Houston, TX)
Medical Errors Costing U.S. Billions Apr 8, 2008
However, over that time, there were increases in post-operative respiratory failure, post-operative pulmonary embolism or deep vein thrombosis, post-operative sepsis (blood infection), and post-operative abdominal wound separation/splitting. The most common types of medical errors were bed sores, failure to rescue, and post-operative respiratory failure. (Health-Finder)
Medical errors cost US $8.8B, result in 238,337 potentially preventable deaths: HealthGrades study Apr 8, 2008
However, four indicators, post-operative respiratory failure, post-operative pulmonary embolism or deep vein thrombosis, post-operative sepsis, and post-operative abdominal wound separation/splitting, increased when compared to 2004 ... Post-operative sepsis. (EurekAlert!)
Vancomycin Resistant MRSA Apr 6, 2008
Most infections stay confined to the skin, but open wounds and surgical incisions can allow the bacterium to enter and gain access to the internal organs or bloodstream, leading to sepsis. Therefore, MRSA is usually seen in those who have invasive surgery or reduced immunity. (Suite101.com)
Methicillin-Resistant Staph Aureus Apr 5, 2008
Whether it is MRSA or methicillin-sensitive Staphylococcus aureus (MSSA), the bacterium can cause many types of infections, including but not limited to cellulitis, pneumonia, wound infections, endocarditis, and sepsis. Even with resistance to several antibiotics, there are still other antibiotic regimens to use for treatment, including the antibiotic vancomycin. (Suite101.com)
Hidden Tragedy Of Under-reported Neonatal Mortality In Northern Vietnam Apr 1, 2008
6 million child deaths worldwide each year are the result of six causes: pneumonia, diarrhea, malaria, neonatal sepsis, preterm delivery and asphyxia at birth. (May 29, 2005) The most accurate estimates of the causes of child deaths to date, published in the March 26, 2005 of THE LANCET, reveal that worldwide more than 70% of the 10. (Science Daily)
Blood Goes Stale—and Fairly Quickly Mar 31, 2008
They had more frequent occurrences of a blood disease called sepsis. And more of them died during the year after surgery. (Science News for Kids)
Help for Heinous Hemorrhoids Mar 28, 2008
Left untreated, a hemorrhoid with a blood clot can lead to such serious complications as gangrene or sepsis. Sometimes, very large prolapsed hemorrhoids must be surgically removed. (Suite101.com)
Study: Surgery patients more likely to have problems if they receive older blood transfusions Mar 27, 2008
The findings were similar to smaller studies of colorectal cancer surgery patients in Denmark, cancer surgery patients in Spain, sepsis patients in Canada and trauma patients in Colorado. Each of those studies found higher rates of various complications in patients who received older transfused blood when compared with patients who got fresher blood. (Chippewa Falls Chippewa Herald, WI)
Algorithm Finds The Network -- For Genes Or The Internet Mar 20, 2008
Using this tool, researchers may be better able to identify and understand communities of genes and their networks as well as how they cooperate in causing diseases, such as sepsis, virus infections, cancer and Alzheimer's disease ... Zhang and Ruan's algorithm is so versatile that it has been applied to identify the community structure of a network of co-expressed genes involved in bacterial sepsis ... The problems he studies are diverse, ranging from stress responses and virus infection in... (Science Daily)
FLW soldier’s wife accused of baby killing lost another child in 1999 Mar 20, 2008
They allegedly found the baby in the arms of the mother, and an autopsy concluded the baby had died of dehydration, starvation, malnutrition and possible sepsis. The family which also included three other children, ages 2, 5 and 14 was living in terrible conditions, including urine and feces, the paper said, citing the U.S. Attorney's Office in Kansas City. (Waynesille Daily Guide, MO)
Duration of Red-Cell Storage and Complications after Cardiac Surgery Mar 20, 2008
003), and sepsis or septicemia (4. 0% vs. 2. (New England Journal of Medicine)
Minorities, Whites Get Equal Care In Hospitals, Study Shows Mar 15, 2008
5, 2008) Blacks have almost double the rate of severe sepsis -- an overwhelming infection of the bloodstream accompanied by acute organ dysfunction -- as whites, according to recent. (Jan. (Science Daily)
Grieving Mother Continues To Blame State Mar 15, 2008
Castro said doctors at the hospital told her that Chelsey died of heart failure caused by sepsis, an overwhelming infection that can attack the body's organs very quickly. But an autopsy report concluded that she died of kidney failure and lupus, according to the Office of the Chief Medical Examiner. (FOX61, CT)
