Brick by brick: Martial arts champ hasn't let kidney disease slow him down Sep 1, 2008
Just 31/2 years ago, Brown had a medical checkup after his limbs began swelling from fluid retention (edema) and was diagnosed with renal failure, congestive heart failure and diabetes -- all at once -- from a simple blood test. "Just like that," he says, in a hushed whisper. (Florida Today)
Nigeria: Anxiety Lingers Over Yar'Adua Aug 31, 2008
Buhari, the candidate of the All Nigerian Peoples Party, ANPP, in the 2007 polls, made his position known on the president, who was said to be recuperating in King Fahd Hospital, Saudi Arabia, after successfully undergoing renal transplant surgery, just as many members of the National Assembly declined comments on the president's ill-health on the grounds that they were not aware of the situation. The only member of the House of Representatives who spoke on the matter, Hon. Leo Ogor, said... (allAfrica.com)
Global Survey Highlights Need For Cancer Prevention Campaigns To Correct Misbeliefs, Survey Finds Aug 31, 2008
(May 16, 2007) Drinking moderate amounts of alcohol is associated with a decreased risk of renal cell cancer, review of twelve relevant articles. . (Science Daily)
Louisiana Dialysis Caregivers and Volunteers Brace for Hurricane Gustav; Prepare to Maintain Power, Continued Access for Patients to Life-Saving Treatment Aug 30, 2008
About Kidney Care Partners Kidney Care Partners is an alliance of patient advocates, dialysis professionals, providers and manufacturers working together to improve the quality of care for individuals with End Stage Renal Disease (ESRD). For more information, visit. (PR Newswire)
Nigeria:Yar'Adua Undergoes Surgery in Saudi Arabia Aug 30, 2008
In fact, reliable sources confirmed to Saturday Vanguard last night that the president underwent, serious renal transplantation and has been under intensive care. But his condition is said to be very stable. (allAfrica.com)
Novel Trial Design Aims To Speed Drug Development Aug 29, 2008
(May 21, 2002) Researchers from the National Cancer Institute (NCI) reported today that the molecularly targeted drug bevacizumab slowed tumor growth in patients with metastatic renal cell carcinoma, the most. (Feb. (Science Daily)
Kidney International Aug 29, 2008
Researchers in evaluate the prevalence of malignancy in satellite renal lesions, and its significance in nephron-sparing surgery. Read the. (Nature News Service)
Terminally ill cancer patients occupy drug adviser's HQ Aug 29, 2008
The medicines, Sutent, Avastin, Nexavar and Torisel, do not cure advanced renal cancer but slow its progression, giving the patient a slightly longer life expectancy. Nice - which has just reversed a controversial decision to disallow the NHS's use of Lucentis, which treats age-related blindness, after agreeing a cost-cutting deal with the manufacturer - ruled that the four kidney cancer drugs gave an average of only five to six extra months of life. (guardian.co.uk)
Angioplasty Scoring System Predicts Risk of Death Aug 29, 2008
Their analysis indicated that the MCRS provided "excellent" predictions overall and in specific groups of patients categorized by age, gender, diabetes, renal failure, low ejection fraction and multi-vessel disease. The researchers found that 97 percent of patients had a MCRS below 10, indicating low to intermediate risk. (MEDLINEplus)
Affymax, Takeda narrow Hematide focus Aug 29, 2008
Takeda and Affymax are continuing to investigate Hematide for the treatment of anemia related to chronic renal failure. Reader Comments. (San Jose Business Journal, CA)
Opinion: Singapore system best for SA Aug 28, 2008
The accounts can, however, also be used to pay for expensive outpatient care such as chemotherapy, renal dialysis, or antiretroviral drugs. The Singapore government also established the Medishield, Medifund and Eldershield funds. (iAfrica.com)
A Man with Abdominal Pain, Nausea, and an Elevated Level of Serum Creatinine Aug 28, 2008
Intrinsic Renal Disease. Acute Renal Failure and Pancreatitis ... From the Renal Division, Beth Israel Deaconess Medical Center (T.I.S.); the Departments of Radiology (A.E.S.) and Pathology (L.D.C.), Massachusetts General Hospital; and the Departments of Medicine (T.I.S.), Radiology (A.E.S.), and Pathology (L.D.C.), Harvard Medical School all in Boston. (New England Journal of Medicine)
Widespread Amyloid Deposition in Transplanted Human Pancreatic Islets Aug 28, 2008
Before the first implantation, the treatment of the patient, who had a functioning renal transplant, was switched to the Edmonton immunosuppression protocol (i. e., daclizumab, tacrolimus, and sirolimus). (New England Journal of Medicine)
NHS funding 'risk to cancer care' Aug 27, 2008
For example it said a complex renal cancer procedure estimated to cost the NHS about 25,000 could only be coded as kidney removal which under the tariff which is worth 4,000. Meanwhile, the tariff breaks technology investment into a series of bands based on an NHS average. (BBC News)
Indias Advinus Therapeutics inks collaboration pact with Genzyme ... Aug 27, 2008
It's product and service portfolio is focused on rare disorders, renal disease, orthopaedics, organ transplant, and diagnostic and predictive testing. The company has 400 scientists worldwide working on various research and development projects. (TopNews)
Facial Transplantation Shows Promise for Severe Disfigurement Aug 26, 2008
The patient had no impairments in renal or hepatic function and no infections arose. Hyperglycemia occurred soon after surgery and then reappeared 3 months later. (RMGH Health News)
Woman on dialysis for 22 years inspires others with her faith, energy Aug 26, 2008
The life expectancy for dialysis patients 40 to 44 years old is seven to 11 years, according to the United States Renal Data System. For patients ages 60 to 64, the life expectancy drops to four to six years. (Athens Banner-Herald)
Cross-donor system planned for region's kidney patients Aug 26, 2008
I don't think that there are any ethical issues" to expanding the number of trades, said Dr. Paul Morrissey of Rhode Island Hospital, chairman of the Renal Transplant Oversight Committee. ''It's just setting up the mechanism to carry it out.". Even tough critics such as Dr. Lainie Friedman Ross, medical ethicist at the University of Chicago, agree that the paired-exchange system can be fair. (Yahoo News -- Organ Donation & Transplants)
Doctors back cancer drug protest Aug 26, 2008
We have not yet made a final decision on the use of drugs to treat renal cancer. " Campaigners have until Friday to comment on Nice's draft guidance rejecting four cancer drugs, including Sunitinib. 7:46am todaynbsp; Add your commentName: Email: * Location: ** e.g. 123-123Comment: Please note: All HTML tags will be ignored. Format Text: By posting a comment, I confirm that I have read and agree to the . Comments are not moderated but we will react if anything that breaks the rules comes to our... (Oxford Mail)
Kidneys With Small Tumors Okay for Transplantation Aug 26, 2008
The organs had come from 38 patients who had a kidney removed for presumed renal cell cancer and from 3 deceased donors ... "Our experience," they conclude, "suggests that kidneys from patients with small renal tumors who have elected to undergo radical nephrectomy (removal) might provide a valuable resource for many patients with end-stage renal failure that, to date, has been largely overlooked.". (MEDLINEplus)
TV Land Gets its 'Scrubs' on and Goes on Rounds During a Labor Day Marathon on Monday, September 1 Aug 26, 2008
As Turk treats his hernia patient and Elliot treats her potential lupus patient, J.D. becomes attached to his patient who is in renal failure. 6:00 p.m.. (Yahoo! Wire -- Entertainment News)
Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2 Aug 25, 2008
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is characterized by the formation of multiple fluid-filled cysts that destroy the kidney architecture resulting in end-stage renal failure ... Surprisingly, over-expression of wild-type PKD2 in renal cell lines failed to inactivate Cdk2 and consequently had no effect on cell proliferation. (BioMed Central)
A total stranger’s totally selfless act Aug 24, 2008
Her husband, Steven Zmuda, a diabetic who undergoes nightly dialysis because of chronic renal failure, is set to receive a healthy kidney donated by a complete stranger just looking to save a life and help out a family ... Then last September, Steven was diagnosed with end-state renal, or kidney, failure. (New Haven Register, CT)
Physical Activity May Lessen Kidney Cancer Risk Aug 23, 2008
During 8 years of follow-up, 1238 cases of renal cell cancer occurred ... Established risk factors for renal cell cancer include smoking, high blood pressure, and being overweight, but the disease's link to levels of lifetime physical activity remained unclear ... "These findings present strong evidence for a link between physical activity and reduced renal cell cancer risk," Moore said. (MEDLINEplus)
Praying for a miracle/"Every day, 17 people die waiting for an organ transplant." Aug 22, 2008
"After a year, we were able to convince a renal doctor to do a biopsy of her kidney. We were sure it was rejection; however, she had toxicity in the kidney from the Prograff, and it had caused damage," Cindy explained. That damage put Ashlie in renal failure, and she is in the last stage of renal failure at this time. (Nevada Journal, IA)
Consistent exercise prevents rare skeletal muscle condition Aug 22, 2008
The decreased filtration rate by the kidneys can result in damage to the renal and kidney system. The most severe complication of rhabdomyolysis is acute renal failure ... Studies report acute renal failure for this condition between 5-16. (Leavenworth Lamp, KS)
Preeclampsia Raises Risk of Serious Kidney Disease Aug 22, 2008
WEDNESDAY, Aug. 20 (HealthDay News) -- Women who've experienced the pregnancy complication known as preeclampsia face a much greater risk of end-stage renal disease, new research suggests. In fact, says the report in the Aug. 21 issue of the New England Journal of Medicine, the rate of end-stage renal disease (ESRD) was between 3 ... "If you have had preeclampsia, you should be aware that you are at increased risk for renal and cardiovascular disease, and you should try to reduce that risk,"... (MEDLINEplus)
Peritoneal Dialysis Nurse Aug 21, 2008
Company Overview Brentwood-based Renal Advantage Inc. (RAI) was founded by veteran health care executives and is the fourth largest provider of outpatient dialysis services in the country. It operates more than 70 freestanding renal dialysis centers in 10 states ... Renal Advantage Inc. is the fourth largest provider of dialysis services in the United States. (Florida Today)
Preeclampsia and the Risk of Later End-Stage Renal Disease Aug 21, 2008
NEJM -- Preeclampsia and the Risk of End-Stage Renal Disease ... Preeclampsia and the Risk of End-Stage Renal Disease ... Background It is unknown whether preeclampsia is a risk marker for subsequent end-stage renal disease (ESRD). (New England Journal of Medicine)
Age, Renal Tubular Phosphate Reabsorption, and Serum Phosphate Levels in Adults Aug 21, 2008
1 We used data from the Gubbio Population Study to analyze serum phosphate levels and renal phosphate handling in relation to age in 2107 men and 2560 women (age range, 18 to 97 years) ... Early-morning samples of blood and urine were collected under fasting conditions to examine renal tubular function ... Renal tubular phosphate handling was assessed as. (New England Journal of Medicine)
Preeclampsia — A Glimpse into the Future? Aug 21, 2008
Complications include maternal stroke, renal failure, and placental abruption; offspring ... From the Renal Unit and Department of Medicine, Massachusetts General Hospital, Boston (R.T.) ... Preeclampsia and Subsequent Renal Disease. (New England Journal of Medicine)
Preeclampsia Raises Kidney Failure Risk Aug 21, 2008
The newest results found that among all women who had given birth at least once, the annual risk of developing kidney failure was only 1 in 27,000, with the problem, also known as end-stage renal disease or ESRD, surfacing after an average of 18 years ... "Indeed, the likelihood that chronic renal failure did not develop, even among women with three previous episodes of preeclampsia, was greater than 99 percent," they wrote. (Newsmax)
India lets Kashmir leader travel Aug 20, 2008
Mr Geelani, who is in his seventies, is suffering from renal cancer. An official in Indian-administered Kashmir said Mr Geelani, whose Indian passport was impounded in 1981, would be given a new one. (Yahoo News -- Kashmir Dispute)
Nine-year-old Kye Loveless Tackles Diseases With Bravery And Resolve Aug 20, 2008
"I rushed to the hospital because we had called them a couple of times in the past when Kye got really puffy in the face. They said it was probably allergies." Then Kye, setting down her frozen cappuccino, piped in saying "They kept giving me Benadryl!" Leeonne continued: "So, I kept giving her Benadryl and it got to the point where she had jowls and no eyelids because she had gotten so puffy. So her godmother took her up to the doctor and found out that she had to be taken to the hospital. When... (Ithaca Times, NY)
Legalizing the Organ Trade? Aug 20, 2008
"It is not a good idea to legalize payment for organ donors as such payment institutionalizes the belief that the wealthy ill have property rights to the body parts of the poor," says Professor A. Vathsala, director of the adult renal transplantation program and head of nephrology at Singapore's National University Hospital. The Singapore Medical Association has also come out against such payment. (Time.com)
Affitech and Omeros Enter Into Antibody Discovery and Development Agreement Aug 19, 2008
MASP-2, or mannan-binding lectin-associated serine protease-2, mediates activation of the complement system via the lectin pathway and is linked to multiple potential indications across a wide range of inflammatory diseases including macular degeneration, rheumatoid arthritis, transplant rejection and cardiovascular and renal ischemia-reperfusion injury. "This agreement marks an important milestone in our MASP-2 program, and ensures that Omeros can access high-affinity, fully human antibodies... (PR Newswire)
Pair of firms attempt renal care response Aug 19, 2008
A pair of firms attempt to respond to the expanded need for renal care ... Liberty Dialysis Hawaii LLC, which took over former St. Francis Medical Center's outpatient renal dialysis program in 2005, has 14 clinics on five islands, each with a different capacity, and they are adding shifts, said Jane Gibbons, executive vice president ... About 2,300 people statewide have renal or kidney failure and need dialysis or a transplant to sustain life, he said. (Honolulu Star-Bulletin)
Dearth of dialysis beds 'serious' for hospitals Aug 19, 2008
" Oahu is often closed to dialysis patients from other islands, said Dr. Jim Jones, one of four nephrologists or kidney specialists on Maui. He said he has been called to take patients from the Big Island and Kauai when there was no place for them on Oahu. Kauai has one kidney specialist, and the Big Island has one in Hilo. Dr. Jared Sugihara, a nephrologist who goes to the Big Island regularly to see patients with kidney disease, said the availability of beds for dialysis patients on Oahu has... (Honolulu Star-Bulletin)
More of this story Aug 19, 2008
Reid has been diagnosed with renal cell carcinoma (RCC) and has been given approximately one year to live, but he wants to spend that year doing what he loves. Reid said he wants to spend that time not only with his wife, but also with his kids at the high school. (Atmore Advance, AL)
Toxic Foods for Dogs Aug 18, 2008
Grapes and raisins (which are dried grapes) will trigger acute renal (kidney) failure. They kidneys act as filters for toxins in the dog s body, therefore, when the kidneys are not functioning properly, toxins accumulate in the body and lead to death due to toxins. (Suite101.com)
Husband and wife's lives hang in the balance Aug 17, 2008
Vivian Nowakowski, 43, of High Street is suffering from end-stage renal failure, meaning her kidneys are no longer working to maintain the right chemical balance in her body. She needs an organ transplant, but isn't allowed to have her kidney transplant operation at Yale-New Haven Hospital without someone to take care of her after surgery. (New Britain Herald, CT)
Outcry over TV kidney competition Aug 17, 2008
"The scenario portrayed in this programme is ethically totally unacceptable," said Professor John Feehally, who has just ended his term as president of the UK's Renal Association. "The show will not further understanding of transplants," he added. (Yahoo News -- Reality TV)
Marco Maldonado, 12, at home, recovering Aug 16, 2008
Maldonado was suffering from renal dysplasia and needed a kidney transplant. His father was approved as the donor, but the family needed to raise the funds for after-surgery care for both father and son before the surgery could take place. (Beatrice Daily Sun, NE)
Declaration Opposes Transplant Commercialism, Transplant Tourism And Organ Trafficking Aug 16, 2008
In an introduction to the Declaration, Dr. Francis Delmonico, professor of surgery at Harvard Medical School, emeritus professor of renal transplantation at the Massachusetts General Hospital in Boston, and the Director of Medical Affairs at The Transplantation Society (TTS), noted that with the increasing use of the Internet and the willingness of patients in rich countries to travel and purchase organs, organ trafficking and transplant tourism have become global problems. Through these... (Science Daily)
Blood Pressure Response To Daily Stress Provides Clues For Better Hypertension Treatment Aug 16, 2008
We think there is a defect in their kidneys, in the normal mechanisms that allow them to excrete salt, said Dr. David Pollock, renal physiologist at MCG s Vascular Biology Center and a program project leader. When blood pressure goes up due to stress, their kidneys ought to get rid of more salt so their blood pressure will come down, and they don t.. (Science Daily)
We need cancer drug rationing Aug 16, 2008
Jonathan Waxman, Professor of Oncology at Imperial College, London, called in The Times for NICE to be abolished, and Professor Karol Sikora, another senior cancer specialist, described the renal cancer decision as a tragedy. Background. (Times Online)
Rituximab Promotes Healing in Common Kidney Disease Aug 16, 2008
"Whether this may apply to other (similar kidney conditions) and may translate into long-term protection from renal function loss and the potentially life-threatening complications remains to be established," the researchers wrote. More information. (Health-Finder)
TRANSPLANT SERIES 2 of 4: A True Friend Aug 15, 2008
When Steinberg was diagnosed with end-stage renal disease, or kidney failure, at first, Justis didn't take the news too seriously ... It had been a long road, having his life dramatically shifted from being a college athlete to being diagnosed with end-stage renal disease, and then through the dialysis and the search for a donor that followed. (Dallas County News, IA)
Froedtert tops in renal transplant survival Aug 14, 2008
Froedtert has highest renal transplant survival rate - The Business Journal of Milwaukee ... Froedtert has highest renal transplant survival rate ... For the second year in a row, Transplant Center has the highest renal transplant survival rate in the region, and is ranked No. 1 of the 15 largest kidney transplant centers in the Midwest. (Milwaukee Business Journal, WI)
Anti–Glomerular Basement Membrane Disease after Alemtuzumab Aug 14, 2008
It is licensed for use in the treatment of chronic lymphocytic leukemia, and it is increasingly used in the treatment of autoimmune diseases (particularly multiple sclerosis) and as an induction agent in renal transplantation. Although alemtuzumab is a potent immunosuppressant, several groups have described the paradoxical occurrence of autoimmune disease after its use, including thyroid disease and cytopenias. (New England Journal of Medicine)
Angiotech receives CE Mark approval of HemoStream(TM) Chronic Dialysis Catheter Aug 12, 2008
About the HemoStream Chronic Dialysis Catheter Incidences of End Stage Renal Disease (ESRD) requiring dialysis are a rapidly growing challenge in healthcare worldwide. When kidneys fail, function of the kidneys can be partially replaced using a process called hemodialysis. (Canada Newswire)
Georgetown Medical Center collaborates to develop cancer research database Aug 12, 2008
The expanded collaboration will grow to include a clinical database of prostate, glioblastoma and renal cancer. Together, the institutions will work to establish a robust portfolio of research collaborations, supported by a state-of-the-art biobanking infrastructure and protocol, using Indivumed's established scientific approach, and a multidimensional, integrated clinical and molecular database of cancer. (EurekAlert! -- Business News)
Keryx Biopharmaceuticals, Inc. Announces Second Quarter 2008 Financial Results Aug 9, 2008
Keryx to Host Investor Conference Call on Monday, August 11, 2008 at 8:30am EDT NEW YORK, Aug. 8 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: ), a biopharmaceutical company focused on the acquisition, development and commercialization of medically important, novel pharmaceutical products for the treatment of life-threatening diseases, including renal disease and cancer, today announced its results for the second quarter ended June 30, 2008 ... ABOUT KERYX BIOPHARMACEUTICALS,... (PR Newswire)
Slow firefighters Aug 8, 2008
freetime wrote on Aug 4, 2008 9:23 AM:" Someone brought up the fact that it took the ambulance crew a while to get to the scene! Do they realize that the crew has to get through traffic because drivers that do not follow laws about pulling over to allow emergency vehicles through, not sitting in the middle of intersections or even trying to beat the ambulance by running red lights before the crew gets to the light! As to people saying that the hospital is not equip to take care of patients with... (Helena Independent Record, MT)
Alcohol Consumption Declining, According To Results Of New Study Aug 8, 2008
(May 16, 2007) Drinking moderate amounts of alcohol is associated with a decreased risk of renal cell cancer, review of twelve relevant articles. (Mar. (Science Daily)
TRANSPLANT SERIES 1 of 4: Life Change Aug 8, 2008
Steinberg was diagnosed in December of 2002 with end-stage renal disease, or kidney failure, and required a kidney transplant ... "Just not knowing when there's going to be any insight at all." End-stage renal disease, otherwise known as kidney failure, signifies that a person's kidneys function so poorly that they can no longer keep you alive ... He received his Medicare card in the mail, which his health care coverage required him to sign up for since his end-stage renal disease qualified him... (Dallas County News, IA)
Monitoring Hormone May Improve Kidney Failure Outcomes Aug 8, 2008
"FGF-23 helps regulate serum phosphate levels; and we know that, among patients with kidney failure, elevated phosphate is associated with more rapid progression to renal failure and earlier death," study leader Dr. Myles Wolf said in an MGH news release. "The results of this study suggest that we need to be concerned about phosphate control even for patients whose serum phosphate levels are normal, and that may involve routine screening for FGF-23.". (MEDLINEplus)
Phoebe welcomes counsel Aug 8, 2008
6 million Willson Hospice House, where construction is set to begin in November, and $3 million renovations to the main hospital building for renovations for physical therapy and renal services, Fischer said. Phoebe s new PET/CT scanner, an x-ray device, is operational and serving about seven patients a day, he said. (Albany Herald)
Row over NHS kidney drug decision Aug 7, 2008
Although there are treatments available, none of them "cure" advanced renal cell carcinoma or cancer that has spread from the initial tumour. But they can help extend a patients' life by around five to six months. (BBC News)
Lessons From The Segway Guy Aug 7, 2008
"You don't say to someone, 'I can't wait for you have to end-stage renal failure,' " so they can try out his latest dialysis technology, Kamen says wryly. Kamen's one big effort to develop a product that would create buzz has yet to really take hold, five years after its launch. (Forbes -- Technology)
Pfizer, Roche Cancer Drugs Rejected by U.K. Agency on Cost-Effectiveness Aug 7, 2008
Pfizer's Sutent, Roche and Genentech Inc.'s Avastin, Bayer and Onyx Pharmaceuticals Inc.'s Nexavar and Wyeth's Torisel shouldn't be used as part of government-funded treatment for metastatic renal cell cancer, the National Institute for Health and Clinical Excellence, or NICE, said today in an e-mailed statement ... As many as 2,000 patients are diagnosed with metastatic renal cell carcinoma per year in the U.K., or about 29 percent of total kidney cancer patients. (Bloomberg -- UK)
LabCorp joins battle against kidney disease Aug 7, 2008
End state renal disease has become a major economic burden for the federal government, with the 400,000 patients on dialysis consuming 6 percent of the Medicare budget. "By combining critical clinical data with sophisticated information technology and expert treatment guidance, we believe our program can improve patient outcomes and save valuable health care dollars," said David P. King, president and CEO of Burlington-based LabCorp. (Business Journal of the Greater Triad Area)
Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis Aug 7, 2008
Background Fibroblast growth factor 23 (FGF-23) is a hormone that increases the rate of urinary excretion of phosphate and inhibits renal production of 1,25-dihydroxyvitamin D, thus helping to mitigate hyperphosphatemia in patients with kidney disease ... From the Renal Unit (O.M.G., T.I., J.A.R.-H., H.T., A.S., K.S., R.T., M.W.), Endocrine Unit (M.M., H.J.), and Biostatistics Center (H.L.), Department of Medicine, and the Pediatric Nephrology Unit, Department of Pediatrics (H.J.), Massachusetts... (New England Journal of Medicine)
Targeted drug therapy found effective in patients with common form of immune-mediated kidney disease Aug 6, 2008
The disease, which is characterized by the loss of large amounts of protein in the urine, leads to impaired kidney function that may ultimately require dialysis or renal transplantation ... "Whether this may apply to other [similar kidney conditions] and may translate into long-term protection from renal function loss and the potentially life-threatening complications remains to be established," they wrote. (EurekAlert!)
BELLUS Health moves forward on nutraceutical and pharmaceutical fronts - Reports Results for First Half of 2008 Aug 5, 2008
The clinical endpoint will be similar to that of the first trial with a focus on renal function and a target p-value of 0. 05. (Canada Newswire)
