Proton Pump Inhibitors Increase Risk Of Bone Fractures, Study Finds Aug 13, 2008
Proton pump inhibitors a class of drugs commonly prescribed to control and prevent symptoms and complications of peptic ulcer disease and GERD (reflux) are widely used by patients for many years. The study looked at people aged 50 and older who had hip, spinal, or wrist fractures and were matched by a control group with no history of hip, spinal or wrist fractures. (Science Daily)
Powerful Antacid Drugs Raise Fracture Risk Aug 13, 2008
PPIs are powerful antacid drugs prescribed for peptic ulcer disease, gastroesophageal reflux disease (GERD) and other related conditions ... "From this newest article, the comfortable zone looks like a length of time longer than the other studies, seven years, which is a nice amount of time. That's enough time for any type of peptic ulcer disease to improve," Schnoll-Sussman said. (MEDLINEplus)
COPD Patients Have High Mortality Rate from Ulcers Jul 17, 2008
"The little existing data on the association between COPD and prognosis following complicated peptic ulcer disease have suggested that the mortality rate is higher among ulcer patients with COPD," they point out ... Medication to prevent ulcers should be considered for COPD patients with risk factors for peptic ulcer disease, especially patients on steroids, which appear to increase the risk and mortality of complicated peptic ulcers, Christensen and colleagues advise. (MEDLINEplus)
Medical research is essential to improving the economy and bettering lives May 7, 2008
He notes that the human papillomavirus vaccine, the antibiotic elimination of H. pyloriinduced peptic ulcer disease, and the all-trans-retinoic acid cure of promyelocytic leukemia are all cost-effective advances that have improved lives and lowered costs. Of course, these advances took years to achieve, and long-term robust funding of research was necessary for their potential to be realized. (EurekAlert!)
Treating Stomach Infection Early Protects against Cancer May 6, 2008
It's been unclear when doctors should screen and treat people with antibiotics -- other than immediate relatives of patients with stomach cancer and peptic ulcer disease -- or when to treat H. pylori infection for maximum benefit, Fox said. He and his colleagues created mice prone to accelerated H. pylori infection and progression to stomach cancer. (MEDLINEplus)
Early Treatment Of Stomach Infection May Prevent Cancer May 3, 2008
Although H. pylori infection is now recognized as the major cause of both peptic ulcers and gastric cancer, and has been classified as a group I carcinogen by the World Health Organization, physicians are not sure whom to screen and treat with costly antibiotics, aside from first degree relatives of gastric cancer patients and those with peptic ulcer disease, he adds. Since it typically takes several decades for gastric cancer to develop in those who are susceptible -- which is estimated to be... (Science Daily)
Interventions designed to improve the quality and efficiency of medication use in managed care: a critical review of the literature - 2001-2007 Apr 8, 2008
Predominant strategies were: educational interventions (n=20, including dissemination of educational materials, and group or one-to-one educational outreach); monitoring and feedback (n=22, including audit/feedback and computerized monitoring); formulary interventions (n=66, including tiered formulary and patient copayment); collaborative care involving pharmacists (n=15); and disease management with pharmacotherapy as a primary focus (n=41, including care for depression, asthma, and peptic... (BioMed Central)
A Key Miscommunication Mar 6, 2008
She had a history of congestive heart failure, mitral regurgitation, hypertension, atrial fibrillation, hypothyroidism, peptic ulcer disease, and depression. She had no history of coronary artery disease or cardiac. (New England Journal of Medicine)
Meridian Bioscience keeps good times rolling in 1Q Jan 22, 2008
John Kraeutler, president and chief operating officer, said in a news release that growth was led by the company's tests for the hospital-acquired infection clostridium difficile; helicobacter pylori, which causes peptic ulcer disease; and toxogenic E. coli. During the quarter, Meridian also introduced two rapid tests for upper respiratory infections: TRU Flu and TRU RSV.. (Cincinnati Business Courier, OH)
ASGE offers guidelines on endoscopic treatment of dyspepsia Dec 22, 2007
These nonspecific symptoms can be indicative of an underlying diagnosis such as peptic ulcer disease, GERD, functional disorders (nonulcer dyspepsia), and malignancy ... Dyspepsia is not only a convenient descriptor for upper-gastrointestinal (GI) symptoms, but also a marker for the risk of structural disease: malignancy is present in 1 to 3 percent of patients with dyspepsia, and peptic ulcer disease in another 5 to 15 percent ... In many patients with dyspepsia who have peptic ulcer disease,... (EurekAlert!)
HIV-positive Patients have a Low Prevalence Of H Pylori In Gut Oct 19, 2007
Patients with chronic active gastritis have evidence of H pylori infection in over 90% of cases and in 70-100% of those with peptic ulcer disease. However, the reason for low incidence of H pylori infection in HIV-positive patients was still not very clear. (Science Daily)
Many Patients Don't Report Use of Over-the-Counter Pain Drugs Oct 17, 2007
But in people with gastrointestinal problems, the painkillers can worsen indigestion, upset stomachs and peptic ulcer disease. With prolonged use, they can also cause bleeding or liver problems. (MEDLINEplus)
Causes of Chest Pain Sep 18, 2007
Pulmonary, Gastrointestinal, and Musculoskeletal, Not Just Cardiac. Chest pain is typically associated with a heart attack, but that's not the only cause. (Suite101.com)
Nobel Laureate to work at PSU Sep 13, 2007
Marshall and co-recipient J. Robin Warren received the prize "for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease," according to www. nobelprize. (Daily Collegian, PA)
Brain-gut Relationship In Those Suffering With Stomach Pain Or Discomfort To Be Studied Sep 7, 2007
Patients with peptic ulcer disease, a history of drug or alcohol abuse, and past abdominal surgeries will be excluded from the trial. Women who are pregnant and patients whose reading skills are insufficient to complete self report questionnaires will also be excluded. (Science Daily)
Peptic Ulcer Disease Jul 19, 2007
The Role of Helicobacter pylori. Gastric and duodenal ulcers were long thought to be the cause of stress and spicy foods until Helicobacter pylori was discovered. (Suite101.com)
Helicobacter Pylori Treatment Jul 18, 2007
It is now evident that Helicobacter pylori is a contributing agent of peptic ulcer disease (Ables, et al., 2007). With this information at hand, it is now possible for patients with this condition to be treated. (Suite101.com)
Clinical Trials Update: June 27, 2007 Jun 28, 2007
Diabetes Mellitus, Type 2. Gout (Hyperuricemia). (Health-Finder)
Class planned for July to help tobacco users quit Jun 12, 2007
Smoking is a major factor in coronary heart disease and stoke, may be casually related to malignancies in other parts of the body and has been linked to a variety of other conditions and disorders, including slowed healing of wounds, infertility and peptic ulcer disease. For the first time, the Surgeon General includes pneumonia in the list of diseases caused by smoking. (Rolla Daily News, MO)
H. Pylori Cured Faster with Addition of Two Agents May 29, 2007
Standard treatment for Helicobacter pylori, a gastrointestinal bacterial infection associated with gastritis and peptic ulcer disease, includes two antibiotics and a proton pump inhibitor. However, this regimen fails to eradicate the bacteria in about 25 percent of patients. (MEDLINEplus)
Salt reduction may cut stomach ulcer risk May 24, 2007
23/05/2007 - High-salt diets may encourage the growth of Helicobacter pylori bacteria in the stomach, said to be the cause of millions of cases of gastritis and peptic ulcer disease each year, says a new study that may have added implications for salt reduction in foods. The new study, presented yesterday at the 107th General Meeting of the American Society for Microbiology in Toronto, indicates that high concentrations of salt in the stomach appear to induce gene activity in the bacterium,... (FoodNavigator.com)
NAC wears many hats May 8, 2007
Avoid NAC if you have peptic ulcer disease. I wouldn't combine NAC with seizure medications, nitrates or other chelating drugs. (Shoals TimesDaily)
Chocolate linked to low blood pressure Apr 25, 2007
BACTERIUM AND ASTHMA Helicobacter pylori, the main cause of peptic ulcer disease, might have a beneficial effect in reducing the risk of asthma and allergies, a study published in the journal Archives of Internal Medicine suggests. Researchers questioned 7,663 men and women about their history of asthma, allergic rhinitis and allergy symptoms, and tested them for antibodies to H. pylori. (International Herald Tribune -- Health)
Abbott Announces FDA Approval of a New Coated Niaspan Tablet Apr 7, 2007
Important Safety Information Niaspan is contraindicated in patients with allergies to any of its ingredients, active peptic ulcer disease, significant or unexplained persistent liver dysfunction, or arterial bleeding. Niaspan should not be substituted for equivalent doses of immediate-release niacin. (PR Newswire)
New Potential Health Benefit Of Olive Oil For Peptic Ulcer Disease Feb 15, 2007
Already fabled for an array of health benefits, extra virgin olive oil a centerpiece of the Mediterranean Diet may have a new role in helping to prevent and treat Helicobacter pylori (H. pylori) infections, which cause millions of cases of gastritis and peptic ulcer disease each year, researchers in Spain report ... have discovered why the bacterium Helicobacter pylori, which causes peptic ulcer disease, is sensitive to metronidazole, a critical component ... A more general term, peptic ulcer... (Science Daily)
Heartburn Treatment May Increase Bile Reflux Feb 14, 2007
A new study may explain why individuals treated for acid reflux with proton-pump inhibitors (PPI) still experience reflux symptoms. Researchers from the Lynn Health Science Institute in Oklahoma City, OK, treated 15 individuals with significant complaints of heartburn, with either a PPI or with a placebo. (Science Daily)
Australia Day Honours - honouring the achievers Jan 26, 2007
Dr Barry James MARSHALL, Subiaco WA. For service to medicine and medical research, notably the discovery of the Helicobacter pylori bacterium and its role in gastritis and peptic ulcer disease ... Dr John Robin WARREN, Northbridge WA. For service to medicine and medical research, notably the discovery of the Helicobacter pylori bacterium and its role in gastritis and peptic ulcer disease. (Sydney Morning Herald -- Australia)
Clues To Cause Of Difficulty With Swallowing In Children Jan 19, 2007
Eosinophilic esophagitis (EE) is disease that was first described in children only 20 years ago, but has shown a rising incidence in both children and adults. An inflammatory condition of the esophagus, its symptoms including vomiting, heartburn and difficulty in swallowing. (Science Daily)
Findings May Improve How People With Chronic Heartburn, Precancer Of The Esophagus Are Screened Dec 6, 2006
Researchers in the Oregon Health & Science University Digestive Health Center are first to report that screening people with chronic heartburn or pre-cancer of the esophagus in an office setting using a "skinny scope" is as accurate, less expensive and less risky than a traditional sedated screening in a procedure room -- and patients prefer it. The findings are published online and in print in this month's issue of the American Journal of Gastroenterology. (Science Daily)
Suffering From Chronic Constipation? Nov 28, 2006
A more general term, peptic ulcer disease (PUD), is also in use. Most ulcers are associated. (Science Daily)
WA names Australians of Year Nov 26, 2006
Professor Barry Marshall and Emeritus Professor Robin Warren were named as WA's Australians of the Year for their discovery of the cause of gastritis and peptic ulcer disease. In its reasons for giving the pair the award, the National Australia Day Council said they "have transformed our understanding of the cause of stomach ulcers". (The Australian)
Gregan a finalist for Aussie of the Year Nov 9, 2006
Other finalists include Professor Barry Marshall and Emeritus Professor Robin Warren who are joint Nobel laureates for their discovery of the cause of gastritis and peptic ulcer disease. But scientist and environmentalist Dr Tim Flannery is the award's favourite according to one betting agency. (Sydney Morning Herald -- Australia)
Clinical Trials Update: Nov. 1, 2006 Nov 2, 2006
Healthy Patient Studies. Irritable Bowel Syndrome (IBS). (Health-Finder)
20 Things You Didn't Know About... The Nobel Prizes Oct 4, 2006
Marshall and his colleague Robin Warren later won the 2005 Nobel Prize in Medicine for their discovery of "the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease.". 19 If you can't win a Nobel, try for an , offered since 1991 by the Annals of Improbable Research for scientific work "that cannot or should not be reproduced.". (Discover Magazine)
Nobel for medicine awarded Oct 2, 2006
2005: Barry J. Marshall and Robin Warren, of Australia, fortheir work in how the bacterium Helicobacter pylori plays a role ingastritis and peptic ulcer disease. 2004: Richard Axel and Linda B. Buck, both of the United States, for their work in studying odorant receptors and the organization of the olfactory system in human beings. (USA Today -- News)
Cancer And Infections: Are There Common Mechanisms? Sep 26, 2006
have discovered why the bacterium Helicobacter pylori, which causes peptic ulcer disease, is sensitive to metronidazole, a critical component. . (Science Daily)
Stomach can protect itself from digestion Aug 13, 2006
Peptic ulcer disease is caused by the stomach digesting itself, when this balance is disrupted. Stomach ulcers are commonly caused by infection with the bacteria Helicobacter pylori, and use of non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen and naproxen. (Orlando Sentinel -- News)
Seriousness is still unclear Aug 1, 2006
If the bleeding is caused by peptic ulcer disease, he said, that might also be serious. If the surgery is successful, he said, recovery time is likely to mean at least a week of hospitalization. (The Miami Herald)
AGA Institute presents cutting-edge research during DDW May 20, 2006
Dr. Marshall and J. Robin Warren, MD, a pathologist at the Royal Perth Hospital, later showed that patients could be cured of their peptic ulcer disease only when the bacteria were eradicated from the stomach. Additionally, a session on "Wnt Signaling in the Digestive Tract: From Development to Carcinogenesis" (Tuesday, May 23, 10:30 a.m. to 12:00 p.m. PT; West Hall B), will describe the pivotal role Wnt signaling plays in gut development and repair and characterize how Wnt contributes to the... (EurekAlert!)
Stomach receptor for H. pylori discovered May 5, 2006
Blocking this interaction could lead to new drugs that reduce the risk of peptic ulcer disease or gastric cancer ... This interaction can lead to peptic ulcer disease, gastric adenocarcinoma, and non-Hodgkins lymphoma of the stomach ... "H. pylori alters acid production and can lead to increased acid outputs which causes peptic ulcer disease. The means through which H. pylori causes gastric cancer are more complex but likely involve alterations in gastric epithelial cell responses that are... (EurekAlert!)
Treatment reduces gastric ulcers in at-risk patients using long-term NSAIDS Mar 30, 2006
He currently studies Gastroesphogeal Reflux Disease(GERD), managements strategies to reduce NSAID-induced ulcer disease, and the clinical impact of H. pylori testing and treatment in suspected peptic ulcer disease. About the American Journal of Gastroenterology The clinical journal in gastroenterology: The American Journal of Gastroenterology meets the day-to-day demands of clinical practice. (EurekAlert!)
Nexium shown to reduce gastric ulcers in at-risk patients using long-term NSAIDS Mar 23, 2006
Griffin MR et al. Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons ... Griffin MR et al. Nonsteroidal anti-inflammatory drug use and death from peptic ulcer disease in elderly persons ... Griffin MR et al. Nonsteroidal anti-inflammatory drug use and death from peptic ulcer disease in elderly persons. (EurekAlert!)
Stomach Bacteria Linked to Iron Deficiency Jan 14, 2006
Moreover, this relationship holds true even in the absence of peptic ulcer disease, which can cause iron-deficiency anemia through hemorrhage, the researchers report in the American Journal of Epidemiology. "For the first time in a national sample of the US population, we found an apparent link between H. pylori infection and iron deficiency" and iron-deficiency anemia, lead author Dr. Victor M. Cardenas, from the University of Texas at Houston, told Reuters Health. (MEDLINEplus)
A comparison of oral omeprazole and intravenous cimetidine in reducing complications of duodenal peptic ulcer Jan 11, 2006
Gastrointestinal bleeding is a common problem and its most common etiology is peptic ulcer disease. Ulcer rebleeding is considered a perilous complication for patients. (BioMed Central)
