Simple Test Detects Foot Problems with Diabetes Oct 18, 2008
Since diabetes is a condition which causes sugar in the blood to go outside normal ranges managing blood sugar is critical to preventing neuropathy, which can reduce feeling in the feet. Podiatrist Dr. Brian Ash said, Eventually as you lose feeling in your feet, you could step on something and not know it, you could walk around for weeks with a staple in your foot. (WOKR13 Rochester)
Avigen Initiates Opioid Withdrawal Trial in Partnership With NIDA, Columbia University and the New York State Psychiatric Institute Oct 15, 2008
Other forward-looking statements include the statements that AV411 may have the potential to provide better tolerability with fewer side effects than existing treatments and that Avigen may pursue development of AV411 for the treatment of opioid withdrawal and dependence and chemotherapy-induced neuropathy. These statements are subject to risks and uncertainties that could cause actual results to differ materially from those projected in these forward-looking statements. (Primezone Releases)
Durability of Stavudine, Lamivudine and Nevirapine among Advanced HIV-1 Infected Patients with/without Prior Co-administration of Rifampicin: A 144-week Prospective Study Oct 14, 2008
8%) patients discontinued d4T due to neuropathy and/or symptomatic lactic acidosis. Conclusions. (BioMed Central)
Tricyclic Antidepressants Oct 3, 2008
The TCAs are used to treat many kinds of chronic pain, especially neuropathic pain like diabetic neuropathy. They are not painkillers as such and cannot be taken "as needed"; daily use is required. (Suite101.com)
Sangamo BioSciences to Present at the UBS Global Life Sciences Conference Sep 17, 2008
The most advanced ZFP Therapeutic(TM) development program is currently in Phase 2 clinical trials for evaluation of safety and clinical effect in patients with diabetic neuropathy and ALS. Other therapeutic development programs are focused on cancer, HIV/AIDS, neuropathic pain, nerve regeneration, Parkinson's disease and monogenic diseases. Sangamo's core competencies enable the engineering of a class of DNA-binding proteins known as zinc finger DNA-binding proteins (ZFPs). (PR Newswire)
Integra LifeSciences Will Feature Its New EndoRelease Endoscopic Cubital Tunnel Release System At American Society for Surgery of the Hand Annual Meeting Sep 17, 2008
Cubital tunnel syndrome is the second most frequent compressive neuropathy in the upper extremity, after carpal tunnel syndrome. Cubital tunnel syndrome affects men 3-8 times as often as women and occurs most commonly in patients between 30-60 years in age. (Primezone Releases)
Chamomile tea and diabetes Sep 17, 2008
The activity of the ALR2 enzyme and the accumulation of sorbitol are both thought to play a role in the development of diabetic complications, such as those involving the kidneys (nephropathy), the eyes (cataracts and retinopathy) and nerve cells (neuropathy). What were the results of the study. (NHS Choices)
8 natural ways to ease pain Sep 15, 2008
Capsaicin: For arthritis, shingles, or neuropathyWhat the science says: An active component of chile pepper, capsaicin temporarily desensitizes pain-prone skin nerve receptors called C-fibers; soreness is diminished for 3 to 5 weeks while they regain sensation. Nearly 40 percent of arthritis patients reduced their pain by half after using a topical capsaicin cream for a month, and 60 percent of neuropathy patients achieved the same after 2 months, according to a University of Oxford study ...... (MSNBC -- Health)
Poor Nerve Function Tied to Disability in Seniors Sep 10, 2008
This type of nerve damage, also referred to as "peripheral neuropathy," can be responsible for disability in older people without diabetes as well, lead researcher Dr. Elsa S. Strotmeyer of the University of Pittsburgh, told Reuters Health. She and her colleagues found a direct and independent relationship between function of the sensory and motor nerves in the legs and feet of elderly people as well as walking speed, balance, and other measures of physical ability. (MEDLINEplus)
Gene Therapy Prevents Blindness In An Animal Model Of Mitochondrial Dysfunction Sep 9, 2008
ND1 and ND4 are mutated in nearly all cases of Leber hereditary optic neuropathy (LHON). LHON is the most common mitochondrial disorder and is characterized by a loss of vision. (Science Daily)
Medical opinion: Burning feet could be peripheral neuropathy Sep 8, 2008
A You may be suffering from peripheral neuropathy. Neuropathy is any type of nerve damage, and peripheral neuropathy is nerve damage to the feet or hands ... There are many causes for peripheral neuropathy. (Yuma Daily Sun, AZ)
ON THE WEB: See the FDA list Sep 6, 2008
Peripheral neuropathy. Tumor Necrosis Factor (TNF) Blockers. (USA Today -- Money)
Dangers of Fluoroquinolones Sep 5, 2008
Fluoroquinolones can cause long-lasting, even permanent damage, including symptoms like neuropathy (nerve damage) which may lead to severe pain. It is impossible to predict who gets this reaction, but corticosteroids (like prednisone), NSAIDs (like ibuprofen) and caffeine may increase the risk and should not be combined with fluoroquinolones. (Suite101.com)
New pages to have familiar face Sep 3, 2008
I have initiative again to do things," said Keck. "The only bad side-effect I had from the chemo was neuropathy in my hands and feet and now even that is going away. " "It was so hard for me to retire. (Pontiac Daily Leader, IL)
5 Stocks Approaching Greatness Sep 3, 2008
It's been a year since Depomed's stock price got blasted by the failure of Gabapentin GR in a phase III trial for post-herpetic neuropathy. Since then the ProQuin distribution deal has collapsed and the product is no longer mentioned in quarterly statements. (MSNBC -- Business)
Hydrating Kidney Patients With Sodium Bicarb Has Little Effect Sep 3, 2008
Neuropathy is a serious kidney disorder and a known complication of exposure to the iodine in the contrast agent used during angiography. The risk of neuropathy related to contrast agents ranges from 2 percent in low-risk people to 50 percent in those who are at high-risk ... Previous animal studies and one randomized clinical trial have suggested that hydration with sodium bicarbonate may be effective in preventing contrast-induced neuropathy. (Health-Finder)
LETTER: Medicines should be taken only as directed Sep 1, 2008
About a year ago I was diagnosed with Diabetic Neuropathy (pain from diabetes). After a few months, the pain medicine didn t help much, so I took more of it. (Mattoon Journal-Gazette, IL)
sports briefs. Aug 30, 2008
The youngster was recently diagnosed with Giant Axonal Neuropathy, a rare genetic disorder that causes progressive, irreversible damage to nerve cells and is known to be fatal. Registration and lunch begins at 11:30 a.m. with a 1 p.m. shotgun start. (Community News Weekly, NY)
Senior Notes Aug 27, 2008
Ever been diagnosed with neuropathy and have nowhere to turn other than drugs or surgery. Dr. David Cox of Little Elm Chiropractic will listen as seniors describe, in detail, the pains they have had and will now eliminate. (McKinney Courier-Gazette, TX)
Anticonvulsants, CFS/ME and FM Aug 26, 2008
Anticonvulsants are used in the treatment of epilepsy and bipolar disorder, increasingly also for chronic pain (especially migraines and neuropathy) ... It is also a popular pain treatment, especially for burning or electric shock-like neuropathy. (Suite101.com)
A Historic Meeting For Hannah Aug 26, 2008
They gathered to talk about a rare genetic disease, Giant Axonal Neuropathy. Matt Sames, Hannah's father says, "scientists from France, Stanford, Harvard, Quebec, some of the best minds in this room today, talking about disease for the first time ever.". (FOX23 News, NY)
Support Groups Aug 25, 2008
- Peripheral Neuropathy support group, 10 a.m. second Saturday except August, Glendale Community Church, 6411 Beach Blvd. (904) 244-9719. - Stroke Busters and Mended Hearts support group, 10 a.m.-noon third Tuesday, Shands Jacksonville, 10th floor Coleman Room, Tower 2, 580 W. Eighth St. Includes a lecture and free lunch. (Florida Times-Union)
Medicinal Marijuana Effective For Neuropathic Pain In HIV, Study Finds Aug 8, 2008
"Neuropathy is a chronic and significant problem in HIV patients as there are few existing treatments that offer adequate pain management to sufferers," Ellis said ... The previous studies were conducted with CMCR support by Donald I. Abrams, M.D., Professor of Clinical Medicine at UCSF, who reported efficacy in short-term treatment of HIV neuropathy (Neurology, 2007, 68:515-521); by Mark Wallace, M.D., Program Director for the UCSD Center for Pain Medicine, who found that normal volunteers... (Science Daily)
Medicinal Marijuana Eases Neuropathic Pain in HIV Aug 6, 2008
"Neuropathy is a chronic and significant problem in HIV patients as there are few existing treatments that offer adequate pain management to sufferers," study leader Dr. Ronald J. Ellis, an associate professor of neurosciences, said in an UCSD news release. "We found that smoked cannabis was generally well-tolerated and effective when added to the patient's existing pain medication, resulting in increased pain relief.". (Health-Finder)
Understanding Type 1 Diabetes Aug 5, 2008
"The highest risk is one in 15, but not everyone is at risk, so it s probably something in the environment. Look at everything, all the toxins and viruses and other autoimmunities that may increase risk in a person who may not be at risk. Usually, type 1 tends to be more of risk of Northern European regions like Scandinavia, but it still occurs in Hispanics and African-Americans. If you are diagnosed with type 1 diabetes, it is important to take your prescribed medicine and see your doctor as... (Fox News)
Impaired Ankle Function Seen in Diabetics Aug 5, 2008
NEW YORK (Reuters Health) - People with long-standing diabetes are prone to impaired ankle function, even in the absence of diabetes-related nerve damage, or "peripheral neuropathy," new research indicates. Diabetic peripheral neuropathy -- a progressive deterioration of nerve function in the extremities linked to diabetes -- can trigger chronic pain, numbness, weakness, and tingling sensations in the feet. (MEDLINEplus)
Innovator in Artificial Intelligence Created 'Pleasing' Pastel Portraits Aug 4, 2008
Peripheral neuropathy took away his balance and "caused him to walk as if on a tightrope," said his wife of 40 years, Susan Hodes. Over time, his childhood limp gave way to his using a cane, a walker and, despite his stubborn resistance, a wheelchair. (Washington Post -- Technology)
WEX Announces Presentation at Scientific Conference Jul 26, 2008
Moreover, the actual treatment of cancer can cause pain, with chemotherapy-induced peripheral neuropathy occurring in about half of patients receiving some types of chemotherapy. The global market for pain therapeutics used in cancer patients was approximately US$15. (CCNMatthews Press Releases)
Hot Weather Brings Concerns For Diabetics Jul 25, 2008
"People with diabetes often have neuropathy, and they can't feel their skin burning. And they can have sores end up being ulcers. So that's something really, really important in the summer," said Moore. Ozone levels are also up across the valley, and may aggravate certain diabetes-related complications such as heart disease. (KLAS-TV.com, NV)
Swimmer losing sight, but gains insight Jul 25, 2008
He was diagnosed with Leber hereditary optic neuropathy. There is no treatment, no cure. (News & Observer -- Sports)
U.S. Sued Over Dropping of Benefits for Disabled Jul 24, 2008
The suit's plaintiffs include Eshetu Meri, 51, of Fairfax, a blind man who escaped from Ethiopia, where he was targeted for advocating democracy; Tasim Mandija, 80, of Philadelphia, a native of Albania who suffers from prostate cancer and neuropathy; and Rouzbeh Aliaghaei, 17, an Iranian who suffers from a rare genetic disorder that resulted in autism, seizures, mental retardation and an enlarged head. He came to the United States in 1998 when his parents escaped political persecution. (Yahoo News -- Disabilities and the Disabled)
Easing Pain And Numbness Associated With Diabetes Jul 20, 2008
ScienceDaily (July 19, 2008) To ease pain and numbness associated with diabetes, NewYork-Presbyterian/Weill Cornell physician-scientists are studying a drug previously used for depression to treat peripheral neuropathy ... Those with peripheral neuropathy often endure chronic pain, cramping and sleepless nights that prevent them from living a normal lifestyle ... Dr. Bassem Masri a cardiologist and diabetes specialist at New York-Presbyterian/Weill Cornell and Helen and Robert Appel Clinical... (Science Daily)
Bioremedi Therapeutic Systems Inc Forges Strategic Relationship with Whitaker Wellness Institute Jul 18, 2008
For use by people with diabetic peripheral neuropathy or chronic/acute pain ... HealthLight Series I devices are most commonly used for reducing pain and providing symptomatic reversal of diabetic peripheral neuropathy ... Often associated with diabetic peripheral neuropathy, non-healing wounds can present as serious problem. (Yahoo News -- Press Releases)
Epilepsy Drug Eases Diabetic Neuropathy Pain Jul 18, 2008
A review of previous studies indicates that the seizure drug pregabalin (Lyrica) is safe and effective for relieving diabetic neuropathy, the pain that diabetics often experience in their feet and hands. The analysis of data from seven studies of pregabalin, with dosages of 150, 300, and 600 milligrams daily and study durations from 5 to 13 weeks, is published in the journal Diabetes Care. (Newsmax)
Hannah's Hope Part One Jul 8, 2008
The boy had GAN or Giant Axonal Neuropathy. GAN is an extremely rare, inherited disorder that destroys nerves. (FOX23 News, NY)
Your Health: Wash bare feet off when coming back inside the house (40) Jul 4, 2008
Symptoms to watch out for include fatigue, confusion, loss of appetite, depression, burning tongue, poor memory, weakness and peripheral neuropathy (burning, tingling or numbness in feet or hands). Q:My mother recently had surgery and now is experiencing significant memory loss. (Sioux Falls Tri-State Neighbor, SD)
Your Health: Taking acid-suppressing drugs can deplete body of vitamins (32) Jul 2, 2008
Symptoms of this nutritional deficiency include fatigue, confusion and memory problems, peripheral neuropathy, constipation and depression. Getting off acid-suppressing drugs can be challenging. (Sioux Falls Tri-State Neighbor, SD)
Diabetes: Underrated, insidious and deadly Jul 1, 2008
Poor circulation and a loss of feeling in the extremities, called neuropathy, can lead to severe ulcers and infections; each year in the United States, there are about 86,000 diabetes-related amputations. Diabetes can also take a toll on relationships. (International Herald Tribune -- Health)
Same dance, but a different song Jun 28, 2008
She s suffered through much in the past decade: breast cancer, followed by a disease that left her paralyzed for a year, followed by neuropathy. No one is talking about that. (Albany Democrat-Herald, OR)
Arsenic poisoning at Maine church left mark on body and soul Jun 24, 2008
There's neuropathy in his hands as well. Although they don't hurt, they're so numb he can't feel anything. (Orangeburg Times and Democrat, SC)
Wiihabilitation Jun 22, 2008
His burns had also left him with a condition in which extra bone had grown on his legs, restricting his movements even more, and nerve neuropathy in his foot. When he arrived at the rehabilitation centre, it took four people to help him stand from his wheelchair, and on that first day he managed to take six steps - three with each leg - before collapsing. (Sydney Morning Herald -- Technology)
FDA Approves VELCADE(R) (Bortezomib) for Injection for Patients with Previously Untreated Multiple Myeloma Jun 21, 2008
The safety profile of VELCADE in combination with MP is consistent with the known safety profiles of both VELCADE and MP. In VISTA, the most commonly reported adverse events for VELCADE in combination with MP vs MP, respectively, were thrombocytopenia (52% vs 47%), neutropenia (49% vs 46%), nausea (48% vs 28%), peripheral neuropathy (47% vs 5%), diarrhea (46% vs 17%), anemia (43% vs 55%), constipation (37% vs 16%), neuralgia (36% vs 1%), leukopenia (33% vs 30%), vomiting (33% vs 16%), pyrexia... (PR Newswire)
Nurses' Notes - Cancer survivors will face a new normal life Jun 18, 2008
Pain can be a result of surgery, radiation or peripheral neuropathy (chemotherapy damage to the nerve endings of the fingers and toes). You can take medications to alleviate the symptoms, but some patients need further treatment. (Missoulian, MT)
Sangamo upbeat on drug for diabetic nerve damage Jun 17, 2008
If the Richmond biotech company's final trials prove successful, the drug could offer a potential cure to the 20 million Americans who suffer the painful malady diabetic neuropathy. But before Sangamo can enter the $92 billion U.S. diabetes care market, it will need to expand its mid-stage tests of the drug, the company told attendees of the Meeting in San Francisco on June 6. (East Bay Business Times, CA)
Lumbar Spinal Stenosis Jun 12, 2008
e., nerve-conduction studies and electromyography) can often be quite helpful in differentiating symptoms related to spinal stenosis from those due to a peripheral neuropathy. In general, a patient with clinically significant spinal stenosis will have electromyographic evidence of multilevel lumbosacral radiculopathies with essentially normal nerve-conduction studies, whereas a patient with clinically significant peripheral neuropathy will have just the opposite findings (i. (New England Journal of Medicine)
A Man with Headache and Visual Changes after Liver Transplantation Jun 12, 2008
Anterior Ischemic Optic Neuropathy. -->Infections after Liver Transplantation. (New England Journal of Medicine)
The cause of all hereditary sensory and autonomic neuropathy type II cases has been established Jun 11, 2008
Their recent results will hereafter help to explain all the cases of hereditary neuropathy type II.. Hereditary sensory and autonomic neuropathy type II (HSANII) is a severe and early onset disorder that starts early during childhood ... Unfortunately no therapy is currently available for individuals suffering from hereditary neuropathy type II. In 2004, Dr. Rouleau's team identified the DNA sequence of HSN2 as encoding a novel gene but their more recent investigations have now shown that this... (EurekAlert!)
In remembrance of loved ones Jun 10, 2008
He told those gathered at the Copper Queen Hotel for the dedication service that he had spent five years in a wheelchair due to the neuropathy that took away the feeling in his legs. That can come from the virus as well as from the medications. (Sierra Vista Herald, AZ)
Drug Keeps Type 2 Diabetes at Bay Jun 10, 2008
About 1 in 10 individuals with impaired glucose tolerance shows signs of diabetic retinopathy (damage to blood vessels in the retina that may affect vision), and 5 percent to 10 percent of prediabetic individuals are estimated to have peripheral neuropathy (blood vessel damage in extremities). A drug to treat impaired glucose tolerance and prevent further decline is therefore of great importance. (Newsmax)
Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting Jun 9, 2008
Presentation Details Statistically Significant and Clinically Relevant Results for SB-509 in Development for Treatment of Diabetic Neuropathy SAN FRANCISCO, June 8 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: ) announced today the presentation of encouraging Phase 1b clinical data from its ZFP Therapeutic(TM) program at the 68th Scientific Sessions of the American Diabetes Association (ADA). As disclosed in an oral presentation entitled, "Evidence of Neuroregeneration Using... (PR Newswire)
Older Diabetics' Risk of Cardiac Ischemia Lower Than Thought Jun 9, 2008
Since it is common for people with diabetes to have neuropathy, a type of nerve damage, it was though many of them wouldn't feel any warning pain or it wouldn't feel strong enough to the diabetic to send him or her to a doctor. Study participants, evaluated over five years, consisted of 1,123 adults with type 2 diabetes in the United States and Canada who had no previous cardiac symptoms, diagnosis of coronary artery disease, and normal electrocardiograms. (Health-Finder)
Treating Autism with Vitamin B6 Jun 7, 2008
A very small number of children taking large doses of B6 suffer peripheral neuropathy, which causes numbness or tingling of the feet and hands. However, side effects are rare, and taking magnesium with vitamin B6 lowers the risk of them occurring. (Suite101.com)
Neuromyelitis Optica Jun 5, 2008
The past episodes of acute myelitis and progressive neuropathy suggested that the patient had either. multiple sclerosis. (Suite101.com)
Paclitaxel Poliglumex (OPAXIO(TM))/Capecitabine Regimen Well Tolerated and Active in Metastatic Breast Cancer Jun 3, 2008
"Given the convenient dosing schedule, a 15 minute infusion every 3 weeks, as well as no requirement for premedications and minimal hair loss associated with OPAXIO compared to other taxanes, the goal of the study was to determine if OPAXIO combined with capecitabine, an oral chemotherapy agent, as first- line therapy in metastatic breast cancer would prove to be an active and relatively well tolerated regimen," said Jack W. Singer, M.D., Chief Medical Officer of CTI. "The severe toxicities... (PR Newswire)
Agent orange ‘win’ reversed for ‘blue water’ sailors Jun 3, 2008
By 2001, Haas had developed type-2 diabetes, peripheral neuropathy and loss of eyesight which he claimed were caused by herbicide exposure off Vietnam. His regional VA office denied the claim, saying service connection couldn t be established because Haas had not gone ashore. (Petersburg Progress Index, VA)
Borrowing time for a little girl Jun 3, 2008
That was the day their toddler Hannah was diagnosed with a rare genetic disorder called giant axonal neuropathy. The disease damages the nerve pathways that carry signals from the brain. (Albany Times Union)
Poniard Announces Positive Preliminary Efficacy and Safety Data From Ongoing Phase 2 Trial of Picoplatin in First-Line Treatment of Colorectal Cancer Jun 2, 2008
None of the Phase 1 patients treated with picoplatin exhibited severe neuropathy (Grade 3 or 4), as is commonly seen in metastatic CRC patients treated with oxaliplatin in combination with 5-fluorouracil and leucovorin as part of the FOLFOX regimen. Neurotoxicities were not related to cumulative exposure of picoplatin. (PR Newswire)
Easing The Pain After Cancer Surgery Jun 2, 2008
Monday, June 02, 2008. Acupuncture eases pain in head and neck cancer surgery Posted: 02 June 2008 1510 hrs. (Channelnewsasia.com)
VELCADE(R) (Bortezomib) for Injection Based Treatment Delivers Impressive Complete Response and Survival in Patients With Newly Diagnosed Multiple Myeloma Jun 1, 2008
The reasons for discontinuation included peripheral neuropathy (8%), asthenic conditions (3%) and thrombocytopenia and diarrhea (each 2%). In total, 2% of the patients died and the cause of death was considered by the investigator to be possibly related to study drug: including reports of cardiac arrest, congestive heart failure, respiratory failure, renal failure, pneumonia and sepsis. (PR Newswire)
Multiple Clinical Trials of VELCADE(R) (Bortezomib) for Injection Based Therapies Demonstrate High Complete Remission Rates in Patients with Newly Diagnosed Multiple Myeloma Jun 1, 2008
Side effects included thrombocytopenia, neutropenia, hyperglycemia and peripheral neuropathy ... Side effects were manageable and included hematologic toxicity and peripheral neuropathy ... No grade 4 peripheral neuropathy was observed. (PR Newswire)
Acupuncture reduces pain and dysfunction in head and neck cancer patients after neck dissection Jun 1, 2008
"It does not treat illness, but acupuncture can control a number of distressing symptoms, such as shortness of breath, anxiety and depression, chronic fatigue, pain, neuropathy, and osteoarthritis.". "Cancer patients should use acupuncturists who are certified by the national agency, NCCAOM [National Certification Commission for Acupuncture and Oriental Medicine], and who are trained, or at least experienced, in working with the special symptoms and problems caused by cancer and cancer... (EurekAlert!)
Preventing Lyme Disease: 5 Ways to Avoid Getting... May 29, 2008
"If you do get bitten or notice that characteristic bulls-eye lesion on your body, you should see your doctor right away, said Rahimian. The reason is because there are medicines that prevent you from getting the long-term consequences of Lyme disease. If you have early-stage Lyme disease, oral antibiotics such as doxycycline, amoxicillin, or cefuroxime axetil are most often prescribed. According to the National Institutes of Health (NIH), studies have shown that most patients can be cured... (Fox News)
New Eloxatin(R) (oxaliplatin injection) Prescribing Information in the U.S. Includes Six-Year Overall Survival Data May 28, 2008
Peripheral sensory neuropathy ("tingling or numbness" in the fingers or toes) occurred in 92 ... Partial or total recovery was observed within 18 months following treatment in most patients experiencing grade 3 peripheral sensory neuropathy. (PR Newswire)
TechCoire to host LifeScienceFest in Davis May 23, 2008
of Temecula, which is developing a device to treat diabetic neuropathy. of Sunnyvale, which plans to develop diagnostics and therapies for pregnancy disorders. (Sacramento Business Journal, CA)
Relays for Life in New Milford and Washington celebrate, inspire May 23, 2008
they removed it, and then I started chemo," Mr. Oberndorfer said. "I had neuropathy from the chemo, where you can't feel your hands or feet. " After that, he was cancer free for a few months, but his doctors found another lesion on his liver this winter. "So I had radiation after that," he said. "Right now I'm in a holding pattern. (New Milford Times, CT)
