Cryptic promoter behind spastic paraplegia Jul 14, 2008
By using promoter-less constructs in various experimental settings, we found that the cryptic promoter is active in HeLa, HEK293 and motoneuronal NSC34 cells but not in SH-SY-5Y neuroblastoma cells. We showed that the cryptic promoter directs the synthesis of a SPG4 transcript that contains a shorter 5'-UTR and translates the 60-kDa spastin isoform selectively. (BioMed Central)
Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells Jul 6, 2008
We studied the effect of different antidepressants on BDNF mRNA expression in human neuroblastoma SH-SY5Y cells. Results. (BioMed Central)
Saturday blood drive to benefit children fighting cancer Jul 2, 2008
Young Catie is battling neuroblastoma, a cancer most common in young children, and Catie's mother is helping with this drive to call attention to the need for life-saving blood needed by these children. Catie has already used 58 units of blood during her treatment. (The St. Augustine Record)
Accidental fungus leads to promising cancer drug Jun 30, 2008
Tests in mice showed it worked against a range of tumors, including breast cancer, neuroblastoma, ovarian cancer, prostate cancer, brain tumors known as glioblastomas and uterine tumors. It helped stop so-called primary tumors and also prevented their spread, Ofra Benny of Children's Hospital Boston and Harvard Medical School and colleagues reported. (Scientific American)
Customized 'Wimpy' Polioviruses Designed: A New Path To Vaccines? Jun 30, 2008
16, 2007) The cause of one notorious childhood disease, poliovirus, could be used to treat the ongoing threat of another childhood disease, neuroblastoma. In the March 15 issue of Cancer Research, researchers. (Science Daily)
Identification Of A Tumor Suppressor Gene Associated With Patient Outcome In Neuroblastoma Jun 27, 2008
ScienceDaily (June 27, 2008) Expression of the CHD5 gene is frequently down-regulated in neuroblastomas, and patients whose tumors lacked CHD5 expression were more likely to have shorter event-free and overall survival compared with patients whose tumors expressed CHD5, according to a study in the June 24 issue of the Journal of the National Cancer Institute ... Neuroblastoma tumors often lack one copy of a region on the short arm of chromosome 1, called 1p36 ... In the current study, Brodeur... (Science Daily)
Read more... Jun 26, 2008
To date, Alex's Lemonade Stand Foundation, a registered 501(c)3 charity, has raised more than $19 million towards fulfilling Alex's dream of finding a cure, funding over 80 research projects nationally including those examining leukemia, brain tumors, neuroblastoma, Wilm's tumor, lymphoma, and osteosarcoma among others. Related links. (PNN Online)
Edwardsburg tot's good news comes Friday 13th Jun 26, 2008
"Her University of Michigan doctors "told me that Teigan has taught them that they don't know all there is to know about neuroblastoma," which the happy little girl developed on top of cerebral palsy, epilepsy and mental delays.Carla responded, "You don't know all there is to know about Teigan ... They knew the neuroblastoma was gone, but thought she had another type of cancer. (Dowagiac News, MI)
Kids raise $6,700 Jun 25, 2008
The team of children, named Pocket Full of Sunshine, was started by Kim Perrine, whose daughter Kirsten, a third-grader at the Sharon School, was diagnosed with neuroblastoma, a rare childhood cancer, at 21 months old. After chemotherapy, radiation, two stem cell transplants and multiple surgeries, Kirsten is now cancer-free, but still has significant health issues emanating from her treatment. (NJ.com -- Times)
Facts of (Relay for) Life - The race is not yet won Jun 19, 2008
There are Leukemia, Brain, Neuroblastoma, Wilms tumor, Non-Hodgkin lymphoma and Hodgkin lymphoma just to name a few of the childhood cancers. Cancer is the second leading cause of death in children, exceeded only by accidents. (Grand Coulee Star, WA)
Philip Charles Hair Salon participates in Time For Life event Jun 14, 2008
Along with leukemia he was diagnosed with ganglia neuroblastoma. Doctors told them that it was "very rare" for a child to have two cancers, and they couldn't treat the tumor in his stomach until his leukemia was under control, said Hedges. (Rocky Hill Post, CT)
Gran joins race for this boy's life Jun 14, 2008
Tristan, who is now nine months old, endured gruelling treatment for neuroblastoma, a very rare form of cancer. Normally such a cancer in someone so young would not require such aggressive treatment. (Swindon Advertiser)
Cancer Drug Appears to Help with Aggressive Multiple Sclerosis Jun 14, 2008
Cyclophosphamide has been used in combatting a number of cancers, including lymphomas, multiple myeloma, leukemia, mycosis fungoides, neuroblastoma, ovarian carcinoma, retinoblastoma and breast cancer. The drug affects the function of immune cells known as T and B cells. (MEDLINEplus)
Genetic Susceptibility to Neuroblastoma Jun 12, 2008
NEJM -- Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma ... Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma ... Background Neuroblastoma is a malignant condition of the developing sympathetic nervous system that most commonly affects young children and is often lethal. (New England Journal of Medicine)
Neuroblastoma — Linking a Common Allele to a Rare Disease Jun 12, 2008
NEJM -- Neuroblastoma -- Linking a Common Allele to a Rare Disease ... Neuroblastoma Linking a Common Allele to a Rare Disease ... Neuroblastoma has a notorious reputation among solid tumors of childhood because of its frequently massive and widespread tumor burden. (New England Journal of Medicine)
Health InfoCenter Jun 10, 2008
For more information about the neuroblastoma study. More information on the smoked seafood recall. (WCAX.com, VT)
Survivor's storiesMeet the boy who beat cancer and has written two books for charity Jun 9, 2008
Page last updated at 07:28 GMT, Sunday, 8 June 2008 08:28 UK. Cancer boy's stories help charity. (BBC News -- Health)
Grace's memory lives on through foundation Grace Oughton Cancer Foundation continues, offers support to other families Jun 3, 2008
For two years prior, Crystal, husband Alec and their son, Landon, were allies in their daughter's battle with neuroblastoma, an aggressive form of cancer that usually appears in infants and toddlers ... A year later, Corbin's pediatrician told her a lump in her 6-month-old son's abdomen was probably neuroblastoma ... Neuroblastoma is an aggressive cancer that usually begins in the nerve tissue of infants and toddlers. (Fredericksburg.com, VA)
A wish come true Jun 1, 2008
Jak, of Butte, was diagnosed with a cancer called neuroblastoma when he was 3. The cancer manifested as a tumor in Jak s abdomen, wedged in between important arteries, making it risky to remove surgically. (Montana Standard, MT)
S'ville toddler fights cancer (45) May 31, 2008
Drew Perschon, 2, was diagnosed Nov. 6 with neuroblastoma, a childhood cancer that affects about 700 American children each year. After five rounds of chemotherapy and surgery to remove a tumor, Drew is cancer free and in remission. (Munster Times, IN)
Pediatric Cancer May 27, 2008
Kids Take Nationwide Stand on Neuroblastoma. Alexandra "Alex" Scott's battle with neuroblastoma encourages kids to participate in lemonade stands across the nation ... According to the American Cancer Society, 650 new cases of Neuroblastoma are reported each year. (Suite101.com)
Drug Therapy To Bolster Immune System Cells Found Effective Toward Childhood Cancer May 20, 2008
The combination has the potential to treat different types of childhood cancer, including osteosarcoma, leukemia and neuroblastoma, while possibly sparing young patients from more difficult therapies such as stem cell transplant or more toxic chemotherapy ... Lee's study found similar responses from acute myelogenous leukemia (AML) and neuroblastoma, but using different inhibitors ... For neuroblastoma and AML, the proteasome inhibitors Bortezomib and NPI-0052 were found to have the greatest... (Science Daily)
Heart risks high in childhood cancer survivors May 16, 2008
Dr. Daniel Mulrooney of the University of Minnesota and colleagues conducted the study, which looked at 14,358 survivors of childhood leukemia, central nervous system tumors, Hodgkin's and non-Hodgkin's lymphoma, kidney tumors, bone cancers, neuroblastoma and soft-tissue sarcoma between 1970 and 1986. They compared these to 3,899 of their siblings. (Scientific American)
Family tragedies bring two grieving mothers together May 12, 2008
Amy Brawner had been diagnosed with neuroblastoma in 1994, a cancer which usually affects infants and young children. In Amy s case, the cancer had advanced to Stage 4. (Columbia Daily Herald, TN)
'IT'S ALWAYS THERE': Grieving mothers create living tributes to their children May 11, 2008
He had an extremely aggressive form of childhood cancer called neuroblastoma. In 2004, his family spent more than 200 days and nights in the hospital with him. (Orangeburg Times and Democrat, SC)
Researchers find genes for deadly child tumor May 9, 2008
Finding could lead to new therapies for aggressive neuroblastoma ... BOSTON - An international team of researchers said they have pinpointed three variants of the genetic code that appear to set the stage for aggressive neuroblastoma, the deadliest solid tumor in early childhood ... Because the chance is less than 1 percent that a neuroblastoma will reappear in a family, there is little point in doing genetic screening for the risk, Drs. (MSNBC -- Health)
Gene That Gives Rise To Neuroblastoma, An Aggressive Childhood Cancer, Located May 9, 2008
ScienceDaily (May 8, 2008) Using advanced gene-hunting technology, an international team of researchers has for the first time identified a chromosome region that is the source of genetic events that give rise to neuroblastoma, an often fatal childhood cancer ... The investigators found that the presence of common DNA variations in a region of chromosome 6 raises the risk that a child will develop a particularly aggressive form of neuroblastoma, a cancer of the peripheral nervous system that... (Science Daily)
Gene Variation Linked to Neuroblastoma, a Childhood Cancer May 9, 2008
WEDNESDAY, May 7 (HealthDay News) -- For the first time, a gene linked to the often fatal childhood cancer neuroblastoma has been identified, researchers report ... Neuroblastoma, a cancer of the peripheral nervous system that usually appears as a solid tumor in the chest or abdomen, is the most common solid tumor malignancy seen in early childhood ... Neuroblastoma accounts for 7 percent of all childhood cancers but causes 15 percent of all childhood cancer deaths. (MEDLINEplus)
Neighbors, friends holding PMC fundraiser May 2, 2008
The 8-year-old is fighting neuroblastoma. He was recently in the news for helping to unveil the jersey of Red Sox player David Ortiz that was buried under the New York Yankees new stadium by Boston fans. (North Andover Citizen, MA)
Gene Mutations in Cytogenetically Normal Acute Myeloid Leukemia May 2, 2008
gene (CEPBA), the myeloid lymphoid or mixed-lineage leukemia gene (MLL), and the neuroblastoma RAS viral oncogene homolog (NRAS). We evaluated the associations of these mutations with clinical outcomes in patients. (New England Journal of Medicine)
Chemotherapy Causes Delayed Severe Neural Damage, Study Shows Apr 23, 2008
22, 2008) Cancer treatment with chemotherapeutic agents is often associated with delayed adverse neurological consequences - an occurrence often referred to as "chemobrain" - that may compromise the quality of life of a proportion of cancer survivors. Now, new research demonstrates that treatment with a single chemotherapeutic agent, 5-fluorouracil (5-FU), by itself is sufficient to cause a syndrome of delayed degeneration in the central nervous system (CNS). (Science Daily)
Nerve cancer mutations found Apr 18, 2008
Researchers have identified genetic mutations underlying a childhood cancer of the nervous system called neuroblastoma ... The new results, says study author Yael Moss of the Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, suggest that such inhibitors could provide a therapy for neuroblastoma as well ... Neuroblastoma is deadliest in its non-inherited form. (Nature News Service)
Potential New Target For Treatment Of Solid Tumors In Children Apr 16, 2008
16, 2008) Australian researchers have identified a potential new target for treatment of neuroblastoma, the most common solid tumor among young children ... Researchers report that ODC1 inhibition delayed or prevented the development of neuroblastoma in a clinically relevant animal model, suggesting that suppressing ODC1 could be target for treating this cancer ... Researchers observed 209 patients with untreated neuroblastoma. (Science Daily)
Prostate Cancer Can Be Halted With Anti-inflammatory And Statin Used In Tandem, Study Suggests Apr 15, 2008
14, 2008) Researchers at Rutgers' Ernest Mario School of Pharmacy have shown that administering a combination of the widely used drugs Celebrex (celecoxib, a nonsteroidal anti-inflammatory drug) and Lipitor (atorvastatin, a cholesterol lowering drug) stops the transition of early prostate cancer to its more aggressive and potentially fatal stage. Prostate cancer is the second leading cause of cancer death in men in the United States, with more than a quarter-million new cases appearing each... (Science Daily)
Relay for Life raises money for cancer research Apr 15, 2008
He will be 3 years old this year and has battled neuroblastoma since he was diagnosed at 18 months old. The Quillen Team wore "team Able" on their shirts for the second year honoring his fight. (East Tennessean, TN)
Biomarkers allow doctors to match therapy to patient Apr 14, 2008
At the 2008 Annual Meeting of the American Association for Cancer Research, April 12 16, researchers present data on new biomarkers that can predict response to well known treatments for breast cancer, pediatric neuroblastoma, and kidney and non-small cell lung cancer ... Overexpression of ODC1 is associated with poor outcome in childhood neuroblastoma and represents an important therapeutic target: Abstract 5832 ... Australian researchers have identified a potential new target for treatment... (EurekAlert!)
Motorcylists ride for A.N.N.A. Apr 12, 2008
Anna Needs Neuroblastoma Answers (A.N.N.A.) was started in 2002 in honor of Anna Healey (1996-2006) who suffered from neuroblastoma, a rare childhood cancer. This 501(c)3 Public Charity has raised over 200,000 for neuroblastoma research at Riley Hospital for Children, Indiana University Cancer Research Institute and families living with the devastating disease ... Neuroblastoma accounts for only eight percent of all cancer, but is responsible for 15 percent of all cancer related deaths. (Rensselaer Republican, IN)
Kids shave heads for cancer research Apr 5, 2008
Monday's event was held to recognize and aid Brent McCreesh, a 5-year-old Southport boy who was diagnosed in 2004 with stage 4 neuroblastoma, a form of cancer that occurs in infants and young children. Brent has had six rounds of chemotherapy, two stem-cell transplants, and three weeks of radiation but reached 31 months cancer-free in January. (Valley News, CT)
New Way To Fight Cancer: Protect Healthy Cells With The Silver Shield Apr 2, 2008
Funding from the study came from NIA (part of the National Institutes on Health), the USC Norris Cancer Center and the Associazione Italiana per la Lotta al Neuroblastoma. USC graduate student Changhan Lee and Gaslini's Raffaghello performed key experiments. (Science Daily)
More of this story Mar 29, 2008
In March 2006, shortly after her sixth birthday, she was diagnosed with Neuroblastoma, a cancer of the nerve tissues. For the past two years, she has been receiving regular blood transfusions as part of her treatment. (L Observateur, LA)
Adherex Announces Phase III Trial With STS in Collaboration With the Children's Oncology Group Mar 26, 2008
The goal of this Phase III study is to evaluate in a multi-centered, randomized trial whether STS is an effective and safe means of preventing hearing loss in children receiving cisplatin chemotherapy for newly diagnosed germ cell, liver (hepatoblastoma), brain (medulloblastoma), nerve tissue (neuroblastoma) or bone (osteosarcoma) cancers. Eligible children will be 1 to 18 years of age who are scheduled to receive cisplatin according to their disease-specific regimen and, upon enrollment onto... (CCNMatthews Press Releases)
Falcon Hockey Game Against Michigan State Raised $7,859 For The Peter Eigner Fund Mar 25, 2008
Event Benefited The Family Of Alum Ty Eigner And His Son Peter Who Was Diagnosed With Neuroblastoma ... What sets Peter apart from most other youngsters his age is a battle he fights on a daily basis against neuroblastoma cancer ... Peter was diagnosed with neuroblastoma, most commonly found in male infants under the age of 5, on August 17, 2006. (Bgsufalcons.com)
New Insight Into The Genetics Of Brain Tumor Formation Mar 25, 2008
Neural crest-derived tumors include neuroblastomas and medulloblastomas, which are the most common malignant pediatric solid tumors, as well as paragangliomas (relatively rare tumors of the sympathetic nervous system) and melanomas, the deadliest form of skin cancer ... The Kaelin group demonstrated that the supplementation of 1p-deleted neuroblastoma cancer cells with KIF1B{beta} protein is sufficient to restore apoptosis and identified inactivating point mutations in neural crest-derived... (Science Daily)
Men's Ice Hockey Team Raises Over $12,000 For Cancer Research Mar 20, 2008
The team is part of a collective group named TeamBrent, in honor of Brent McCreesh, a five year old Southport boy diagnosed with Stage IV neuroblastoma in September 2004. TeamBrent was formed to raise awareness and funds to fight all childhood cancers with a focus on neuroblastoma. (Sacredheartpioneers.com)
More pain than most on this road to winter games Mar 17, 2008
A toddler when he was diagnosed with neuroblastoma stage four, a rare and aggressive cancer of the central nervous system, Nicholas spent a year in the Sydney Children's Hospital at Randwick, with his parents, Lyndie and Mark, making it home for less than 30 days in that time. "That first year was a blur," Ms Powell said yesterday. (Sydney Morning Herald -- Australia)
Benefit for young cancer patient Mar 9, 2008
Adam was diagnosed with neuroblastoma, a type of cancer usually found in young children, when he was just 2 months old. Adam has a tumor that has taken over his liver and is comparable to the size of a miniature basketball. (Bismarck Tribune, ND)
Formerly homeless family faces new struggle Mar 7, 2008
The little Vista girl is battling Neuroblastoma and bone marrow cancer ... Sierra was diagnosed in January with neuroblastoma, a rare and often fatal form of childhood cancer. (North County Times)
Jacks family, friends fight back against cancer Mar 6, 2008
Hoping to find a cure for neuroblastoma to help kids like their son and others diagnosed with this type of cancer, Ron and Kim Supino invite the public to a fundraiser to raise money for neuroblastoma research ... This June, it will be two years since their son, Jack, was diagnosed with neuroblastoma, a type of cancer that is usually found in infants and young children ... Jack was almost 8 when he was diagnosed in 2006, and his family and friends have decided to wage a battle against the... (Danvers Herald, MA)
No downgrading of child cancer centres Mar 5, 2008
"Tory spokesman Jackson Carlaw welcomed the plan as a "departure from the previous administration's obsession with centralising services".'WE'LL GO WHERE WE HAVE TO'WHEN Mya Jeffrey fell ill with a suspected stomach infection, her parents expected she would be well again in a few days. But after three weeks, further tests found that she was suffering from a neuroblastoma a cancerous tumour in her stomach. The two-year-old is now undergoing chemotherapy at the Sick Children's Hospital in... (Scotsman)
BGSU Hockey to Raise Funds and Awareness for Children's Cancer Feb 28, 2008
What sets Peter apart from most other youngsters his age is a battle he fights on a daily basis against neuroblastoma cancer. Peter was diagnosed with neuroblastoma, most commonly found in male infants under the age of 5, on August 17, 2006 ... The Children's Neuroblastoma Cancer Foundation (CNCF) is also in existence to support the needs of children and their families fighting neuroblastoma, and to raise funds for research of the disease. (Bgsufalcons.com)
FALCONS CLOSE REGULAR SEASON AGAINST DEFENDING NATIONAL CHAMPION MICHIGAN STATE Feb 27, 2008
Saturday will also feature a fund raising benefit for Falcon alum Ty Eigner, whose son Peter, suffers for Neuroblastoma. A silent auction and proceipts from the evening's chuck-a-puck will be given to the family, who'll be flown in for the game thanks to many Falcon alumni. (Bgsufalcons.com)
Increased chemo 'boosts survival' Feb 27, 2008
A 10-year-study at Addenbrooke's showed about 66% more children with high-risk neuroblastoma survived. Neuroblastoma affects children, mostly aged under five, with about 35 deaths in the UK each year ... Neuroblastoma originates from the cells involved in the development of a baby's nervous tissue. (BBC News -- Health)
Fund founder, families possess strength, hope Feb 22, 2008
has been involved with the Four Diamonds Fund ever since Colby was diagnosed with stage four Neuroblastoma at age 2 in 1994. Colby attended his only Thon in 1997. (Daily Collegian, PA)
Girl, 4, Faces Second Cancer Battle Feb 20, 2008
Samantha Hughes of Heanor, Derbys, England, was diagnosed in October 2005 with neuroblastoma, a cancer of the nerve cells. Following removal of the tumor, a bone-marrow transplant and chemotherapy, Samantha was believed to be in remission. (Fox News)
Six-year-old undergoing cancer treatment receives answer to wish Feb 19, 2008
In July, 2007, Combs, who just celebrated his sixth birthday on Valentine's Day, was diagnosed with Neuroblastoma, a cancer of the sympathetic nervous system, a nerve network throughout the body that carries messages from the brain ... Combs has been undergoing extensive radiation and chemotherapy treatments after being diagnosed with Neuroblastoma last year. (Niles Star, MI)
Viral Therapy Slows Pediatric Tumors in Mice Feb 19, 2008
The targeted viral therapy, dubbed rQT3, slowed neuroblastoma and peripheral nerve sheath tumors in mice, according to findings published in the Feb. 15 issue of Cancer Research ... Neuroblastoma is the most common solid cancer tumor in childhood, most often striking those under age 5 ... However, when MMP activity becomes unbalanced, the enzyme plays a well-documented role in the formation of invasive and metastatic cancers, including pediatric neuroblastoma. (MEDLINEplus)
Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors Feb 15, 2008
CINCINNATI Researchers in a multi-institutional study led by Cincinnati Childrens Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers neuroblastoma and peripheral nerve sheath tumors without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus, according to study results published in the February 15 Cancer Research ... When MMP activity becomes unbalanced, the enzyme plays a well-documented role in the... (EurekAlert!)
North Texas toddler home after stem cell transplant Feb 12, 2008
Doctors released the 2-year-old from Medical City Dallas Hospital, where he spent nearly two months in treatment for neuroblastoma, which is a fast-growing cancer of the nervous system ... Neuroblastoma had spread to Caden's bones, liver and bone marrow by the time his mother discovered a lump on his head last summer ... "We're not talking about his being cured of his neuroblastoma right now," said Dr. Weinthal. (KHOU.com, TX)
Mag: Eric Adelson Feb 2, 2008
Braxton had neuroblastoma, cancer of the nerves ... Good thing, because Braxton still didn't know what neuroblastoma was ... A letter inside from the director of pediatric oncology at the University of Utah read, Braxton Davis was diagnosed in December of 1995 with neuroblastoma. (ESPN -- NHL)
Patty Newbold, AssumeLove.com Feb 1, 2008
Please note: Last issue s Future of Farming article was written on the struggle of little 2-year-old Isaac Lieser with a Neuroblastoma tumor. You may not have recognized it as Erin Slivka s regular column as The Prairie Star accidentally omitted her byline from the article. (Great Falls Prairie Star, MT)
Plant Pathogen Yields Substance To Fight Neuroblastoma Jan 22, 2008
21, 2008) Drug treatment of neuroblastoma, a tumor of the nervous system in children, poses major problems ... The substance from the maize pathogen reprograms neuroblastoma cells in such a way that they behave almost like healthy cells again ... They found out that neuroblastoma cells lose several of their cancer-typical properties when under the influence of the substance: They divide less frequently, show less invasive growth and even their outside appearance resembles healthy nerve cells... (Science Daily)
Around The AL East: Blue Jays Jan 20, 2008
Carlos, now a bench coach with the Florida Marlins, and his wife, Geraldine started the fund in memory of their son C.J., who lost a battle to neuroblastoma, at age 2. BY THE NUMBERS: 10Years since the Jays last had a player go to salary arbitration (Bill Risley). (Boston, TheInsiders.com)
Celecoxib Can Adversely Affect Heart Rhythm, Study Suggests Jan 17, 2008
6, 2007) Neuroblastoma is a form of cancer that develops in the nervous system and it affects small children more commonly than any other tumour type. Now, however, scientists at Karolinska Institutet in. (Science Daily)
St. Jude defines eye cancer gene's role in retinal development Jan 17, 2008
Malfunctioning N-myc genes are often associated with pediatric neural cancers, including neuroblastoma, medulloblastoma and retinoblastoma. Recently, Dyer and his team identified the specific type of cell that gives rise to retinoblastoma, a potentially fatal malignant tumor in the retina that affects about 300 children in the United States annually. (EurekAlert!)
Inside Pitch: Rolen a Jay Jan 15, 2008
Carlos, now a bench coach with the Florida Marlins, and his wife, Geraldine started the fund in memory of their son C.J., who lost a battle to neuroblastoma, at age 2. BY THE NUMBERS: 10 -- Years since the Jays last had a player go to salary arbitration (Bill Risley). (Toronto, TheInsiders.com)