Trade would add years to a life Sep 6, 2008
Fowler was diagnosed in 1978 with Bright's Disease or nephritis - inflammation of the kidney that is commonly caused by autoimmune disorders. The disease, Fowler said, destroys the filtering system in the kidney. (Athens Banner-Herald)
A Man with Abdominal Pain, Nausea, and an Elevated Level of Serum Creatinine Aug 28, 2008
Acute Interstitial Nephritis Due to Proton-Pump Inhibitors. Nephropathy Due to Oral Sodium Phosphate Solution. (New England Journal of Medicine)
Bringing to light a former slave's story in Cohasset Aug 26, 2008
In 1918, Washington died of a cerebral hemorrhage and chronic nephritis and was buried at Woodside Cemetery, a middle-class graveyard, with a granite headstone now undistinguished from hundreds of others. In 2006, when the Massachusetts Historical Commission examined the cemetery for possible inclusion on the National Register of Historic Places, Blight wrote, the panel's report noted that the "most notable Cohasset resident buried in Woodside Cemetery is John Washington . . . an escaped slave... (Boston Globe)
'Multi-target' immune therapy improves outcomes of severe lupus nephritis Jul 2, 2008
Multi-target' immune therapy improves outcomes of severe lupus nephritis ... Multi-target' immune therapy improves outcomes of severe lupus nephritis ... "In our study, multi-target therapy is shown to be superior to traditional therapy for inducing complete remission of class V+IV lupus nephritis, with few side effects," comments Dr. Lei-Shi Li of the Research Institute of Nephrology of Jinling Hospital, Nanjing University School of Medicine in Nanjing,China. (EurekAlert!)
Lupus more severe in patients with Southern European ancestry Jun 12, 2008
According to the results of the research, northern European ancestry is shown to be associated with the relatively milder mucocutaneous (skin) manifestations of SLE, whereas southern European ancestry contributes to more severe manifestations of the disorder such as nephritis (inflammation of the kidneys) and increased production of specific autoantibodies (antibodies that fail to recognise and therefore attack the body's own cells, tissues or organs) ... The association between northern... (EurekAlert!)
Eosinophiluria and Acute Interstitial Nephritis Apr 17, 2008
To the Editor: Over the past two decades, testing for eosinophiluria has gained widespread acceptance as a means of screening for acute interstitial nephritis. The frequent use of this test may be explained, in part, by the subtle clinical presentation of this condition (fever, rash, arthralgia, and renal failure), which mimics other entities, such as pyelonephritis and renal manifestation of various systemic diseases ... Renal biopsy, although used infrequently to diagnose acute interstitial... (New England Journal of Medicine)
World Health Day celebrated in city Apr 8, 2008
The exhibits prepared by the postgraduate students depicted therapeutic diets for diseases such as diabetes, arthritis, peptic ulcers, heart disease and nephritis. The nutrient profile of each diet and their nutrient-related dos and donts were also displayed. (Ludhiana Newsline)
Bradford health summarized Apr 4, 2008
Diabetes, Alzheimer's disease, influenza and pneumonia, nephritis, and hypertension round out the top 10 causes of death in the county. The county has a higher average annual mortality rate than the rest of the state and a higher average annual mortality rate for each of the 10 leading causes of death. (Bradford County Telegraph, FL)
Autism and vaccines: What's the link? Mar 22, 2008
Other symptoms include chorea, athetosis, tremors, convul- sions, pain and numbness in the extremities, nephritis, salivation, loosening of the teeth, blue line on the gums, anxiety, mental depression, insomnia, hallucinations and central nervous system effects [301. Exposure may also cause irritation of the eyes, mucous membranes and upper respiratory tract [269. (Atlanta Journal-Constitution -- Opinion)
Adult With Two Colons Suffers Kidney Atrophy: Rare Diagnosis In The Operation Room Feb 27, 2008
(May 14, 2007) Good patient information is essential for choosing the best treatment for the kidney disease lupus nephritis. A Dutch researcher concludes this following her doctoral research into two methods for. (Science Daily)
Immunosuppressant Further Linked To Birth Defects, Case Study Suggests Feb 13, 2008
In fact, 3 out of 10 babies described in the literature regarding these defects had mothers on MMF because of lupus nephritis. Led by Dr. Antonio Perez-Aytes and Dr. Maximo Vento of the Newborn Research Unit at the Hospital Universitario Materno-Infantil La Fe, in Valencia, Spain, the study describes a 25-year-old Spanish woman who had undergone two kidney transplants. (Science Daily)
A Woman with Postpartum Visual Loss, Shortness of Breath, and Renal Failure Jan 17, 2008
Tubulointerstitial Nephritis Uveitis. Wegener's Granulomatosis or Microscopic Polyangiitis. (New England Journal of Medicine)
Tech startup gets lift at conference Dec 15, 2007
Azano Pharmaceuticals, developing a protein drug product to treat lupus nephritis. CareerTours, creates audio and video "tours" of a company aimed at jobseekers. (AZCentral -- Business)
ZymoGenetics and Merck Serono Initiate Phase 2/3 Clinical Trial of Atacicept in Lupus Nephritis Dec 13, 2007
Trial will Evaluate Safety and Efficacy of Atacicept in Lupus Nephritis and is Intended to Support Marketing Authorization. NEW YORK--()--ZymoGenetics, Inc. (NASDAQ: ZGEN) and Merck Serono, a division of Merck KGaA, announced today the initiation of a Phase 2/3 clinical trial of atacicept in lupus nephritis, a severe form of systemic lupus erythematosus (SLE) ... This study will evaluate the efficacy and safety of atacicept for the treatment of patients with active lupus nephritis. (BusinessWire)
Researchers investigate ways to detect lupus-associated kidney disease Nov 13, 2007
Given that early intervention in lupus nephritis is associated with better treatment outcome, it is imperative that disease activity in the kidney be diagnosed as early as possible ... When the antibodies attack the kidneys, nephritis occurs, often shortening a patients life expectancy ... Dr. Mohan and colleagues screened urine from mice with lupus nephritis for the presence of four compounds VCAM-1, P-selection, TNFR-1 and CXCL 16. (EurekAlert!)
Antiphospholipid Syndrome Oct 21, 2007
cfm/lupus_nephritis in patients with coexisting systemic lupus erythematosus (SLE) ... In patients with coexisting conditions of APS, systemic lupus erythematosus, and lupus nephritis, have been implicated. (Suite101.com)
Anti-inflammatory drugs: When to use? Oct 11, 2007
Aleve, for example warns against constipation, heartburn, abdominal pain, nausea, headache, dizziness, drowsiness, rash, tinnitis, edema, nephritis (inflammation of the kidneys), Nephrotis syndrome, jaundice and hepatitis. According to an article in the American Journal of Medicine, complications related to NSAID use among arthritis patients are responsible for 16,500 deaths per year in the United States. (Saugus Advertiser, MA)
Altadena cemetery breathes new life into Hollywood legend Sep 30, 2007
Official accounts of her death in 1926 at her Altadena home on Boston Street list the cause as tuberculosis and nephritis -- inflammation of the kidney. She may have been the only screenwriter to persuade a dictator to appear in a film: Benito Mussolini played himself in the now-vanished 1923 film "The Eternal City," which La Marr starred in and for which she was reported to have done uncredited writing and producing. (Los Angeles Times)
Number of kidney patients on rise in Bangladesh Sep 17, 2007
The report mentioned diabetes, nephritis and hypertension as the main reasons for kidney damage. Since the treatment facilities are limited in this South Asian country, most of kidney patients are going to neighboring India and other developed countries for treatment, making the country lose millions of hard earned foreign exchange annually, the report said. (Xinhuanet, China)
Americans living longer than ever Sep 13, 2007
Heart disease Malignant neoplasms (cancer) Cerebrovascular diseases (stroke) Chronic lower respiratory diseases Accidents (unintentional injuries) Diabetes mellitus (diabetes) Alzheimers disease Influenza and pneumonia Nephritis, nephrotic syndrome and nephrosis (kidney disease) Septicemia Intentional self-harm (suicide) Chronic liver disease and cirrhosis Essential (primary) hypertension and hypertensive renal disease (hypertension) Parkinsons... (MSNBC -- Health)
Aspreva Provides Update On Lupus Nephritis Development Program Sep 10, 2007
VICTORIA, British Columbia, Sept. 10, 2007 (PRIME NEWSWIRE) -- Aspreva Pharmaceuticals Corporation (NasdaqGS: - ) (Toronto: - ) today announced that Aspreva and Roche have decided not to proceed with a regulatory submission at this time for CellCept as an induction therapy for lupus nephritis ... Preliminary results from the induction stage of Aspreva's phase III clinical trial comparing CellCept (oral mycophenolate mofetil, MMF) to intravenous cyclophosphamide (IVC) for inducing treatment... (Primezone Releases)
Aspreva and Roche Update CellCept Agreement Aug 29, 2007
Through this agreement, Aspreva will contribute to clinical development work in lupus nephritis undertaken by Roche in China ... Forward-looking statements in this news release include, but are not limited to, statements about: our strategy, future operations, clinical trials, prospects and plans of management; our expectations regarding future revenues and expenses; the effects of CellCept on patients; our expectations with respect to our existing collaboration agreement with Roche for the... (Primezone Releases)
Pocatello's history explored Jun 30, 2007
D.W. and Emma's daughter Cammie died young of nephritis (though many Pocatellans still like to think she hung herself in the hallway of the Standrod House). The Standrods were not the most popular people in Pocatello in some circles, but they were respected. (Pocatello Idaho State Journal, ID)
* Aborigines of Wadeye: a portrait of neglect Jun 28, 2007
Residents suffer high rates of heart disease, rheumatic fever, skin sepsis and nephritis. Some 20 to 30 percent of children have perforated ear drums due to chronic infection. (Taipei Times, Taiwan -- World)
Outcasts in their own land Jun 24, 2007
Residents suffer high rates of heart disease, rheumatic fever, skin sepsis and nephritis. Some 20 to 30 per cent of children have perforated ear drums due to chronic infection. (Guardian Unlimited -- World)
Choirs gather to help local girl with lupus Jun 9, 2007
" The event will start at 5 p.m. Saturday at Files Chapel Baptist Church, 900 Dixie St.Crystal, known as "Gabby," was diagnosed with lupus nephritis in 2002.Lupus is a disease of the immune system, and lupus nephritis is an inflammation of the kidney caused by systemic lupus.Since moving to Charlotte with her family in February, her mother, Yolanda Corey, said Gabby has gotten worse. She has been treated for pneumonia, doctors found blood clots, she has undergone chemotherapy, had renal failure... (Foster's Daily Democrat)
Aspreva announces Fast-Track designation granted by the FDA for CellCept in lupus nephritis Jun 7, 2007
VICTORIA, June 6 /PRNewswire-FirstCall/ - Aspreva Pharmaceuticals Corporation (NASDAQ: ; TSX: ASV) today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for CellCept (mycophenolate mofetil, MMF) for the treatment of lupus nephritis. Aspreva is currently evaluating CellCept for the treatment of lupus nephritis in a global phase III study ... In granting Fast Track designation, the FDA noted that type III-V lupus nephritis is a severe inflammation of... (PR Newswire)
Thursday's Stocks to Watch Jun 7, 2007
Aspreva Pharmaceuticals Corp. () () said the Food and Drug Administration has granted fast-track designation for CellCept for the treatment of lupus nephritis. CellCept is Roche's () leading immunosuppressant or "anti-rejection" drug used i 00000719 n combination with other drugs for the prevention of rejection in patients receiving heart, kidney and liver transplants. (Fox News)
Hospitalized student shows signs of improvement Jun 5, 2007
Also, at 2:54 p.m. Friday Shellie posted that doctors believe he became sick from acute post-streptococcal glomerular nephritis, associated with a streptoccal infection. Lee had been diagnosed about three weeks ago with a sinus infection, Wages said Thursday. (Dublin Courier Herald, GA)
Aspreva Completes Expanded Patient Enrollment in Phase III Clinical Trialfor CellCept in Pemphigus Vulgaris May 23, 2007
Forward-looking statements in this news release include, but are not limited to, statements about: our strategy, future operations, clinical trials, prospects and plans of management; our ability to evaluate the potential efficacy of mycophenolate mofetil in the treatment of pemphigus vulgaris; the effects of CellCept on patients; our expectations with respect to our existing collaboration agreement with Roche for the development of CellCept in autoimmune indications; and our two phase III... (PR Newswire)
No Wonder His Name Is A.A. May 19, 2007
"I drank steadily, with a steely determination. I drank on and through peripheral nephritis, alcoholic gastritis, an atrophied brain, an enlarged liver, a damaged pancreas, blackouts, suicidal depression, anonymous bloody sores and DTs so severe that I would have to take the first drink of the morning using a towel hooked round my neck as a pulley, because I was frightened of knocking my teeth out with the glass.". Gill, a dyslexic, says he began drinking as an insecure boarding-school boy who... (New York Post -- Gossip)
Treatment Of Kidney Condition Requires An Individualized Approach May 16, 2007
Good patient information is essential for choosing the best treatment for the kidney disease lupus nephritis. Dutch researcher Cecile Grootscholten concludes this following her doctoral research into two methods for treating lupus nephritis ... The severity of the kidney disease lupus nephritis varies and the side effects of the treatments differ as well. (Science Daily)
Oregon joins national organ donor registryGiving takes more than a 'D' on your driver’s license Apr 29, 2007
Ray received her kidney in 2003 after being on dialysis for three and a half years with glomero nephritis, a disease that causes kidney failure. She was 69 when she received her new kidney; the donor was a 55-year-old woman who died of a stroke. (Albany Democrat-Herald, OR)
Honoured Lomu thanks donor for life Apr 11, 2007
Sign up to the Rugby Heaven newsletter for your chance to win Super 14 tickets. Want to link your website to rugbyheaven. (Sydney Morning Herald -- Sport)
Black-White Life Expectancy Gap Narrows Mar 18, 2007
Moreover, "unfavorable trends in nephritis and septicemia are currently contributing to widening the gap," he said. The researchers concluded that "future efforts to reduce the black-white gap should be aimed at reducing existing inequalities in cardiovascular risk factors, particularly hypertension, and improving access to effective treatment for existing disease that remain underused.". (MedPage Today)
Black-white life expectancy gap narrows, but remains substantial Mar 17, 2007
"Homicide, HIV, and perinatal death, although demonstrating favorable trends, continue to keep the black-white gap unnecessarily large, and unfavorable mortality trends in nephritis [kidney disease] and septicemia [bloodstream infection] are currently contributing to widening the gap," the authors write. The authors emphasize that further narrowing of the gap will require concerted efforts to address the major causes of the remaining gap. (EurekAlert!)
Lupus Nephritis Mar 15, 2007
Kidney Disease in Lupus, RA, and Scleroderma. Kidney disease in lupus typically emerges within the first five years after diagnosis, and it rarely develops in people who have had SLE for as long as 10 years. (Suite101.com)
New Blood Thinner Studied For Patients With Leg And Lung Clots Feb 14, 2007
A new oral blood thinner is being compared to an old standby to see if it works as well and is easier to manage long term, researchers say. Dr. James R. Gossage Jr., pulmonologist at the Medical College of Georgia. (Science Daily)
Mother, daughter get kidneys from brothers Jan 23, 2007
She knows that her diagnosis is chronic glomerular nephritis, which slowly shut down her kidneys. But Schultz will never know for sure why McKasson's kidneys stopped functioning. (Newsday)
Active Ingredient In Common Chinese Herb Shown To Reduce Hypertension Jan 20, 2007
Some 50 million Americans have hypertension, that is, blood pressure measuring above the normal range (less than 120/80 mmHg). If untreated, it can lead to heart attacks, strokes, or kidney disease. (Science Daily)
Genentech Q4 2006 Earnings Call Transcript Jan 11, 2007
We anticipate completing enrollment in the Phase II/III SLE study, EXPLORER, in quarter one 2007; and in the Phase III Lupus nephritis study, LUNAR, in the second half of this year ... We are also preparing to initiate two Phase III Lupus studies, one in SLE and one in Lupus nephritis in the first half of 2007. (Seeking Alpha)
Protein's Effects Essential For Kidney-to-bladder Urine Transfer Dec 27, 2006
-- Nephritis is inflammation of the kidney. The two most common causes of nephritis are infection or an auto-immune process ... Nephritis has the effect of damaging and closing up the microscopic filters. (Science Daily)
Study Explores Link Between Nanoparticles And Kidney Stones Dec 22, 2006
Researchers at Mayo Clinic have successfully isolated nanoparticles from human kidney stones in cell cultures and have isolated proteins, RNA and DNA that appear to be associated with nanoparticles. The findings, which appear in the December issue of the Journal of Investigative Medicine, are significant because it is one step closer in solving the mystery of whether nanoparticles are viable living forms that can lead to disease -- in this case, kidney stones. (Science Daily)
Latest Research in Blood Diseases to be Presented at the Annual Meeting of the American Society of Hematology Dec 7, 2006
Dr. Stanley will explain the critical role of CSF-1 in development and in diseases such as leukemia, solid tumors, osteoporosis, nephritis, and atherosclerosis, and how studies of this growth factor may offer new approaches to innovative treatment options. The lecture will take place on Saturday, December 9, from 12:30 p.m. - 1:30 p.m. in Halls B3-B4. (PR Newswire)
Subsequent Course of Rituxan(R) Improved Outcomes in Rheumatoid Arthritis Patients Who Inadequately Responded to TNF Antagonist Therapy Nov 13, 2006
In addition to RA, Rituxan is being studied in other autoimmune diseases with significant unmet medical needs, including systemic lupus erythematosus, lupus nephritis, multiple sclerosis and ANCA-associated vasculitis. Rituxan, discovered by Biogen Idec, received FDA approval in November 1997 for the treatment of relapsed or refractory, low-grade or follicular, CD20-positive, B-cell NHL. It was also approved in the European Union under the trade name MabThera(R) in June 1998. (PR Newswire)
Mutant Gene Causes Severe Kidney Disease In Infants Nov 8, 2006
Scientists at the University of Michigan Medical School have discovered a previously unknown cause for a severe, early-onset form of kidney disease and renal failure in children: recessive mutations in a gene called phospholipase C epsilon or PLCE1. In children with PLCE1 mutations the kidney filtering units called glomeruli fail to develop normally. (Science Daily)
Carefully Monitored Treatment Can Help Two-thirds Of Those Who Suffer From Depression Nov 6, 2006
More than two-thirds of people who suffer from major depression can become symptom-free if they are willing to work with their doctors and try various treatments to determine which work best for them, which may involve taking different antidepressants or adding cognitive therapy to the mix. More than two-thirds of people who suffer from major depression can become symptom-free if they work with their doctors and try various treatments to determine which work best for them. (Science Daily)
Jonah to be swallowed by Titans Oct 17, 2006
After contracting the rare illness nephritis, which led to kidney failure and a transplant, Lomu has started just one match for New Zealand provincial rugby side North Harbour this season, with his substitute appearances being brief and mostly ineffective. The Gold Coast Titans, based just south of Brisbane, will become the 16th team in the 2007 NRL competition. (Aljazeera.Net)
Titans serious about signing Lomu Oct 16, 2006
Lomu's career nosedived after he contracted the rare illness nephritis, which led to renal failure and the kidney transplant. He started only one match for his North Harbour side in New Zealand's NPC this season, and his appearances off the bench have been brief and largely ineffective. (ABC News Online, Australia -- Sport)
Lomu linked with League Oct 16, 2006
Lomu's career nose-dived after he contracted the rare illness nephritis, which led to renal failure and the kidney transplant. Lomu has started only one match for his North Harbour side in New Zealand's domestic rugby competition this season, and his appearances off the bench have been brief and largely ineffective. (iAfrica.com)
Lomu admits World Cup dream over Oct 2, 2006
Lomu, who made 73 All Blacks appearances, had no regrets over the course his career had taken before or after he contracted the rare illness nephritis that led to renal failure and a kidney transplant two years ago. advertisement - story continues below. (Sydney Morning Herald -- Sport)
Rugby great Lomu concedes All Blacks dream is over Oct 2, 2006
He said he had no regrets over the course his career had taken before or after he contracted the rare illness, nephritis, which led to renal failure and his eventual kidney transplant in 2004. If I had my time over again, I wouldn't do anything differently, he said. (The Star Online, Malaysia -- Sports)
* Lomu in danger of missing out on a Super 14 contract Sep 27, 2006
Lomu's health declined steadily before his operation and he suffered eventual renal failure as a result of the nephritis, undergoing almost daily dialysis treatment until a donor kidney became available. The giant winger, who once terrorized defenders with his powerful, barnstorming runs, remained determined to return to top rugby, against some medical advice, with the hope of playing for New Zealand at the 2007 World Cup. (Taipei Times, Taiwan -- World Business)
Mind-body Connection: How Central Nervous System Regulates Arthritis Sep 8, 2006
In a unique approach to inflammation research, a study by researchers at the University of California, San Diego (UCSD) School of Medicine shows that, in a model of rheumatoid arthritis, inflammation in the joints can be sensed and modulated by the central nervous system (CNS). The research suggests that the CNS can profoundly influence immune responses, and may even contribute to understanding so-called placebo effects and the role of stress in inflammatory diseases. (Science Daily)
New Cell-based Targets For Treating Autoimmune Inflammatory Diseases Sep 5, 2006
Their study, published in the September 2006 issue of Arthritis & Rheumatism, indicates the critical role of platelet function in this dire form of autoimmune kidney disease, crescentic glomerulonenephritis (CGN) ... Article: "Cappuccino Mutation in an Autoimmune-Prone Strain of Mice Suggests a Role of Platelet Function in the Progression of Immune Complex Crescentic Glomerulonephritis," Minako Yoshida, Kan Saiga, Takaaki Hato, Shoko Iwaki, Toshiyuki Niiya, Norimasa Arita, Hiroaki Komori,... (Science Daily)
Living Gifts: Transplant technology is making the surgery easier, but organs are still hard to come by Jul 5, 2006
When he was diagnosed with glomerular nephritis (an inflammation of the tiny bundles of blood vessels that filter blood in the kidney) in October, his kidney was functioning at 24 percent of capacity. OK, he thought, he'd make arrangements and have everything ready for a transplant by the time the function dropped to 20 percent. (Racine Journal Times, WI)
A Man with Staphylococcal Bacteremia and Renal Failure Jun 29, 2006
Staphylococcal Infection and Glomerulonephritis. Staphylococcal Superantigen Associated Glomerulonephritis ... Acute Interstitial Nephritis. (New England Journal of Medicine)
Transplant recipients share stories of survival Jun 27, 2006
Having lost kidney function to glomerular nephritis, he said, he underwent transplant surgery successfully on Sept. 9, 2000, and has attended the games in 2002, 2004 and 2006. This year was different, however, because his family became a donor family. (Leavenworth Times, KS)
A wife and mother gives a part of herself—literally May 13, 2006
The Post-Searchlight - A wife and mother gives a part of herself—literally. Should the Decatur County Commission consider only administrator applications from out-of-towners. (Bainbridge Post Searchlight, GA)
Dagoba Organic Chocolate Recalls "Eclipse 87%," "Los Rios 68%," And "Prima Matera 100%" Dark Chocolate Products Because of High Lead Levels Apr 19, 2006
In addition, sustained consumption of products containing high lead levels can produce lead poisoning which has a number of symptoms including anemia, neurologic effects such as ataxia and irritability, constipation, muscular weakness, and chronic nephritis. The products were distributed nationally through wholesale food distributors and through stores that sell organic, natural and/or specialty foods, as well as via select internet sites. (U.S. Food and Drug Administration -- Alerts)
Concern Over Rapid Rise Of Chronic Kidney Disease Mar 14, 2006
-- Nephritis is inflammation of the kidney. The two most common causes of nephritis are infection or an auto-immune. (Science Daily)
Swimming pools improve health in remote communities: study Feb 26, 2006
DESIREE SILVA: It is very likely that in the long-term we will reduce kidney disease which is called glomerular nephritis and rheumatic heart disease, which we know that amongst the Aboriginal population in Australia there's a highthey record the highest rates in the world of this condition. DAVID MARK: People might find it hard to believe that a pool could provide so much in terms of health benefits. (ABC Online)
Doctor of reforms Jan 8, 2006
During the war, I also taught internal medicine and nursing at St. Luke's nursing school, and when a music teacher left, I taught music too, since I had started playing the piano when I was 10, after I was barred from exercise for a year due to nephritis. What happened to the hospital after the war. (Japan Times Online, Japan)
