Protein Found To Identify Malignant Melanoma Jul 21, 2008
The lesions fell into the category of cutaneous melanocytic neoplasms, a diverse group that includes benign moles; Spitz nevi, a type of mole seen in younger people that can be easily mistaken for melanoma but is not cancerous; and malignant melanoma, which has several phases of growth. Pathologists play a major role in diagnosing and staging skin cancers, by sorting through neoplasms and identifying features. (Science Daily)
Digestive Disease Week study examined ACR's guidelines for CT colonography interpretation Jul 13, 2008
Other DDW research looked at large sessile adenomas; technologies for the preoperative detection of familial pancreatic neoplasms; and the use of peroral cholangioscopy guided stone therapy ... Preoperative Detection of Familial Pancreatic Neoplasms by Endoscopic Ultrasonography (EUS), Multidetector Computed Tomography (CT) and/or Magnetic Resonance Cholangiopancreatography (MRCP) ... Research by Marcia I. Canto, MD, FASGE, associate professor of medicine and oncology, Johns Hopkins University,... (EurekAlert!)
Soccer Parents: Why They Rage Jun 18, 2008
(May 22, 2000) Researchers at Columbia have found that blocking the interaction of two naturally occurring molecules in tumor cells restricts the growth and spread of neoplasms in mice. The finding, published in. (Science Daily)
Daiichi Sankyo Co., Ltd. Announces Acquisition of Biotech Firm U3 Pharma AG May 21, 2008
Daiichi Sankyo's current novel therapeutics portfolio for worldwide commercialization includes CS-1008, an oncologic agent to combat malignant neoplasms, which is in Phase 2. For commercialization only in Japan, Daiichi Sankyo has the rights to market denosumab, or AMG 162, which is licensed from Amgen. (PR Newswire)
Flat Colon Lesions Relatively Common, Associated With Colorectal Cancer Mar 8, 2008
7, 2008) Flat, non-polypoid colorectal neoplasms (NP-CRNs), which may be difficult to detect, appear to be relatively common and may have a greater association with cancer compared with the more routinely diagnosed type of colorectal polyps, according to a study in the March 5 issue of JAMA. ... Prevention has focused on the detection and removal of polypoid (resembling a polyp) neoplasms (a new and abnormal growth) ... "Nonpolypoid colorectal neoplasms are more difficult to detect by... (Science Daily)
Colonoscopy Used to Identify and Remove Flat Colon Lesions: Flat Colon Lesions More Common and More Likely to Be Cancer According to JAMA Study Mar 7, 2008
March 6 /PRNewswire-USNewswire/ -- A study released this week from researchers at the Veterans Affairs Palo Alto Healthcare System in California shows that non-polypoid colorectal neoplasms or flat colon lesions, are more common in Americans than previously thought and may have a greater association with cancer compared to polypoid neoplasms or the more commonly diagnosed colorectal polyp ... The study examined data from a group of 1,819 patients, almost all men with an average age of 64, from... (PR Newswire)
What are simple ways to judge the efficacy of 5-fluorouracil in colonic neoplasm? Feb 23, 2008
The samples came from 68 colonic neoplasms of Han Chinese patients. At the same time, the team also observed the link between TS genotype and IRS of TS. Three genotypes of TS were found: 2R/2R (n = 6), 2R/3R (n = 22) and 3R/3R (n = 40). (EurekAlert!)
Bosses less likely to have cancer Feb 19, 2008
Researchers at the University of Sydney in Australia have found that managers and administrators are significantly less likely to suffer from neoplasms, or cancerous tumours, than all other level of workers. Bosses also have a moderately lower chance of developing mental health problems as well as musculoskeletal conditions, according to the study. (Economic Times)
Bosses less at risk of cancer Feb 17, 2008
Managers and administrators were significantly less likely to suffer neoplasms, or cancerous tumours, than all other level of workers. "Possible reasons for this include managers being less exposed to cancer risk factors or being able to afford to stop working when their health deteriorates," lead researcher Dr Deborah Schofield, from the Northern Rivers University Department of Rural Health, said. (NEWS.com.au)
Bosses less likely to have cancer: Australian study Feb 17, 2008
By occupation, the study found that the relative risk of a manager having neoplasms, or cancerous tumours, was found to be 0. 25 compared to 0. (Yahoo News -- Top Stories)
SHS grad to lead Hepatopancreatobiliary Service at Memorial Sloan-Kettering Jan 21, 2008
In this position, Jarnagin will expand Sloan-Kettering s international leadership in primary and metastatic liver cancers and biliary tract neoplasms and further develop its educational program, which has produced many of the world's leaders. He will remain the Vice Chair for Surgical Services in the department and continue to focus on the diagnosis and treatment of benign and malignant diseases of the liver, bile ducts, gallbladder and pancreas. (Somerville Journal, MA)
Enlarged Prostate Treatment Study Shows Combination of AVODART(R) and Tamsulosin Provides Greater Benefit Than Either Medication Alone Jan 18, 2008
Accessed on January 7, 2008 via (5) Presti JC Jr. Neoplasms of the prostate gland. In: Tanagho EA, McAninch JW, eds. (PR Newswire)
Immunomedics Awarded U.S. Patent for Internalizing Anti-CD74 Antibodies and Methods of Use Jan 8, 2008
The preclinical evaluations of milatuzumab and its isotope, drug, and toxin conjugates have been summarized by R. Stein, M.J. Mattes, T.M. Cardillo, H. J. Hansen, C.H. Chang, J. Burton, S. Govindan and D.M. Goldenberg, in a review published in the September 15, 2007 issue of Clinical Cancer Research entitled ``CD74: a new candidate target for the immunotherapy of B-cell neoplasms. . (Primezone Releases)
Switch-like genes populate cell communication pathways and are enriched for extracellular proteins Jan 5, 2008
Switch-like genes were found to be associated with such diseases as congestive heart failure, Alzheimer's disease, arteriosclerosis, breast neoplasms, hypertension, myocardial infarction, obesity, rheumatoid arthritis, and type I and type II diabetes. In diabetes alone, over two hundred bimodal genes were in a different mode of expression compared to normal tissue. (BioMed Central)
INNOVIVE Pharmaceuticals Presents Preliminary Data at ASH Showing INNO-305 Elicits Immune Response in Patients with Myeloid and Thoracic Neoplasms Dec 9, 2007
ATLANTA--()--INNOVIVE Pharmaceuticals, Inc. (OTCBB:IVPH) today presented results from a pilot study examining INNO-305, a Wilms Tumor Protein (WT1) heteroclitic peptide immunotherapeutic vaccine, in patients with myeloid and thoracic neoplasms ... "Pilot Study of a Wilms Tumor Protein (WT1) Heteroclitic Peptide Vaccine in Patients with Myeloid and Thoracic Neoplasms.". (BusinessWire)
Virtual Colonoscopy As Effective Oct 5, 2007
Friday, October 05, 2007. Virtual colonoscopy as effective as traditional one: study Posted: 05 October 2007 0203 hrs. (Channelnewsasia.com)
Patients With Coronary Artery Disease Appear To Have Increased Prevalence Of Colorectal Tumors Oct 2, 2007
D., of the University of Hong Kong, China, and colleagues investigated the prevalence of colorectal cancer and colorectal neoplasms in patients with newly diagnosed CAD. Participants in the study were from Hong Kong and were recruited for screening colonoscopy after undergoing coronary angiography for suspected CAD from November 2004 to June 2006 ... The researchers found that colorectal neoplasms and advanced lesions were more prevalent (34. (Science Daily)
Americans living longer than ever Sep 13, 2007
Heart disease Malignant neoplasms (cancer) Cerebrovascular diseases (stroke) Chronic lower respiratory diseases Accidents (unintentional injuries) Diabetes mellitus (diabetes) Alzheimers disease Influenza and pneumonia Nephritis, nephrotic syndrome and nephrosis (kidney disease) Septicemia Intentional self-harm (suicide) Chronic liver disease and cirrhosis Essential (primary) hypertension and hypertensive renal disease (hypertension) Parkinsons... (MSNBC -- Health)
NSAIDs may protect against bladder cancer Aug 25, 2007
Karagas and colleagues suggest that, "in light of the chemopreventive effects of NSAIDs including aspirin for other neoplasms, the possibility that they may reduce bladder cancer incidence warrants further consideration. Studies assessing the effect on bladder cancer prognosis are lacking but would be of great interest.". SOURCE: BMC Urology, August 10, 2007. (Scientific American)
NYPD Warns Of Mounting Homegrown Terror Threat; Radical Ways... Aug 16, 2007
Maybe it would be more cost effective (and enhance our national security since Americans are actually at dying) if we refocused our Homeland Security efforts on the dark specter of "in situ neoplasms" (which killed over four times as many people as 9/11 in 2001 alone). Posted by: anonymous | Aug 15, 2007 6:27:53 PM. (The Drudge Report)
A Man with Fever, Odynophagia, Weight Loss, and Rash Aug 16, 2007
NEJM -- Case 25-2007 -- A 60-Year-Old Man with Fever, Odynophagia, Weight Loss, and Rash. Please for full text and personal services. (New England Journal of Medicine)
The ins and outs of West Nile Jul 29, 2007
Malignant neoplasms -- 257. Alcohol-induced deaths -- 22. (Greeley Tribune)
A Woman with Headaches, Weakness, and Strokelike Episodes Jul 12, 2007
NEJM -- Case 21-2007 -- A 58-Year-Old Woman with Headaches, Weakness, and Strokelike Episodes. Please for full text and personal services. (New England Journal of Medicine)
A Boy with a Calcified Mass in the Nose Jun 28, 2007
Neoplasms in the Nasal Cavity. Juvenile Nasal Angiofibroma. (New England Journal of Medicine)
Canine Hemolytic Anemia Jun 18, 2007
Canine autoimmune hemolytic anemia may also occur as a feature in canines with various neoplasms, including leukemia, lymphoma, myeloma and various tumors. In addition, canine AIHA can occur in dogs with other autoimmune disorders, especially systemic lupus erythematosus and. (Suite101.com)
A close-up on pancreatic disease: How do we improve the odds? May 23, 2007
Of the 166 cases, 135 cases were benign [38 serous cystadenomas, 35 mucinous cystic neoplasms, 60 intraductal papillary mucinous neoplasms (IPMN), one cystic papillary tumor, one cystic islet cell tumor] and 31 were malignant (14 mucinous cystic adenocarcinomas, 17 invasive carcinomas in IPMN) ... "Decision-making on the management of small cystic pancreatic neoplasms is currently difficult based on the absence of good, long-term natural history data on the behavior of these lesions. We are... (EurekAlert!)
Scientific Panel Says Erin Brockovich Was Right May 19, 2007
In the mice, there was again no difference in survival, but among the 100 animals getting the highest dose, there were 42 neoplasms, either adenoma of carcinoma. The differences from controls were significant at P. (MedPage Today)
Scientists: Lagoon dolphins are getting sicker May 13, 2007
Oral and genital neoplasms occurred in male and female dolphins at both capture sites. The disease was not detected in any of the 2003 captures but was found in 2004 and 2005 at both sites. (Vero Beach Press Journal)
Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: A phase II-study and historical comparison with the surgical approach Apr 25, 2007
The high complication rate of surgically implanted port catheter systems (SIPCS) represents a major drawback in the treatment of isolated liver neoplasms by hepatic arterial infusion (HAI) of chemotherapy. Interventionally implanted port catheter systems (IIPCS) have evolved into a promising alternative that enable initiation of HAI without laparatomy, but prospective data on this approach are still sparse. (BioMed Central)
Cancer Biomarkers Could Help Guide Treatment Apr 20, 2007
"It is difficult to assess the response of cancer in the brain or lung to treatment, since those neoplasms [tumors] are difficult to access safely. With the proper biomarkers, physicians may be able to tell if a patient is not responding to therapy and alter their treatment strategy accordingly," Dr. Roberto Diaz, a radiation oncology resident at the Vanderbilt-Ingram Cancer Center, said in a prepared statement. "This study provides us with a starting point for understanding how tumors... (MEDLINEplus)
Risk Of Second Malignant Neoplasms After Childhood Leukemia And Lymphoma Apr 18, 2007
A team of 19 researchers from Australia, Canada, Iceland, Singapore, and several European countries has completed what they call the "largest population-based study of absolute and relative risk of second malignant neoplasms (SMNs)" in childhood leukemia and lymphoma survivors. The study, which analyzed data from 13 cancer registries in several countries, found that these survivors have a higher-than-average risk of developing a different type of cancer later in life. (Science Daily)
Illness Leads Need for Disability Coverage Apr 15, 2007
The leading causes of disability due to illness are neoplasms (cancers) and circulatory system diseases, which include heart disease, and mental disorders. (2) Accidents and illness affect people of all ages. (Variety)
Drug used to prevent HIV transmission from mother to child damages DNA Apr 7, 2007
"Genetic Alterations in K-ras and p53 Cancer Genes in Lung Neoplasms From Swiss (CD-1) Male Mice Exposed Transplacentally to AZT," Hue-Hua L. Hong, June Dunnick, Ronald Herbert, Theodora R. Devereux, Yongbaek Kim, Robert C. Sills, Environmental and Molecular Mutagenesis, April 2007, 48:299-306. "Transplacental Carcinogenicity of 3-Azido-3-Deoxythymidine in B6C3F1 Mice and F344 Rats," Dale M. Walker, David E. Malarkey, Steven K. Seilkop, Frederick A. Ruecker, Kathleen A. Funk, Marilyn J.... (EurekAlert!)
No Plateau for Secondary Cancer Risk After Leukemia Mar 21, 2007
March 20 -- Children and adolescents who survive acute lymphoblastic leukemia (ALL) need a lifetime of follow-up because of an elevated risk of secondary neoplasms that continues to climb through adulthood ... Even excluding late "low grade" neoplasms--meningioma and basal cell carcinoma--survivors were at 13 ... "However, even with exclusion of basal cell carcinomas, there remains an impressive increase in carcinoma incidence between 25 and 30 years after induction, reflecting cases of more... (MedPage Today)
Study of leukemia survivors gives hints for better care Mar 21, 2007
Secondary neoplasms are new tumors that develop after successful treatment of an initial cancer ... The St. Jude study found that most of these late-onset secondary neoplasms are low-grade, or slow-growing, tumors that are curablespecifically, meningiomas (tumors arising from the membranes covering the brain) and basal cell carcinomas (skin cancer) ... 17 percent) are estimated to develop secondary neoplasms by 15 years, one in 20 survivors (5. (EurekAlert!)
Read More: FYI: Groopman Mar 17, 2007
Dr. Groopman's research has focused on the basic mechanisms of cancer and AIDS. He did seminal work on identifying growth factors which may restore the depressed immune systems of AIDS patients and on treatment for AIDS-related neoplasms, particularly Kaposi's sarcoma and lymphoma. His book, "How Doctors Think," is a journey into the medical mind, showing how doctors arrive at the correct diagnosis and why sometimes they detour and fail to. (CBS News -- Evening News)
Genetic Pathways To Curable And Incurable Forms Of Pancreatic Cancer Identified Mar 14, 2007
The current study showed that the combination of Kras and an early mutation of Dcp4, in which one copy of the suppressor gene is eliminated, lead to cancer by a different path, beginning with the creation of a distinct class of precancerous lesions in the ductal epithelium called mucinous cystic neoplasms (MCN) ... Conversely, the initial lesions that lead to the more common and deadly form of pancreatic ductal adenocarcinoma, called pancreatic epithelial neoplasms, are tiny enough to be... (Science Daily)
Medical Info Searches on the Web Feb 26, 2007
However, just below that you will see that lung neoplasms is listed as the #1 term. To the far right of the line with lung neoplasms is a highlighted link button, which would take you to a results page on PubMed ... Click on the lung neoplasms term. (Suite101.com)
A 3-Year-Old Boy with Recurrent Episodes of Respiratory Insufficiency Jan 25, 2007
Please for full text and personal services. Debra Boyer, M.D., Sjirk J. Westra, M.D., T. Bernard Kinane, M.D., and James R. Stone, M.D., Ph. (New England Journal of Medicine)
A 19-Year-Old Woman with Thyroid Cancer and Lower Gastrointestinal Bleeding Nov 30, 2006
Please for full text and personal services. Volume 355:2349-2357. (New England Journal of Medicine)
Cancer stem cells start tumors in tests Nov 21, 2006
Colon cancer is one of the best-understood neoplasms (tumors) from a genetic perspective, yet it remains the second most common cause of cancer-related death (in Canada), indicating that some of its cancer cells are not eradicated by current therapies, John Dick of University Health Network in Toronto and colleagues wrote in their report. Click for related content. (MSNBC -- Health)
Radiation Increases Risk Of Second Primary Tumors For Childhood Survivors Nov 2, 2006
Article: Neglia JP, Robison LL, Stovall M, Liu Y, Packer RJ, Hammond S, et al. New Primary Neoplasms of the Central Nervous System in Survivors of Childhood Cancer: a Report From the Childhood Cancer Survivor Study. J Natl Cancer Inst 2006; 98:1528-1537. (Science Daily)
Fallout-thyroid link gets boost Oct 12, 2006
"What we came up with was a much stronger association with thyroid neoplasms (growths, including tumors). It more than doubled." The risk ratio for people with the highest exposure to fallout, compared with those with the least exposure, jumped from 3. 4 times as likely to develop neoplasms to the new study's 7 ... one of the report's authors said that in the 1993 report, only neoplasms of the thyroid were found to be statistically related to fallout doses. (Deseret News)
Cream Prevents Sun Damage In Red-Haired Mice Sep 21, 2006
Eleven neoplasms - most of them squamous cell carcinoma -- developed in the nine control mice within nine weeks after the ultraviolet exposure was stopped. The treated mice developed six tumors but the onset was dramatically delayed: a median of four weeks for the control animals and 25 weeks for the treated mice, a difference that was significant at P. (MedPage Today)
Gene Predisposing To Pituitary Tumors Identified May 26, 2006
Pituitary adenomas are common benign neoplasms, accounting for approximately 15 % of intracranial tumors. Most common hormone-secreting pituitary tumor types oversecrete prolactin or growth hormone (GH), which together with local compressive effects account for their substantial morbidity. (Science Daily)
Positron-Emission Tomography in Cancer Therapy May 4, 2006
2 issue)1 on the powerful diagnostic use of 18F-fluorodeoxyglucose (18F-FDG) as a tracer for hypermetabolic neoplasms raises interesting questions about its potential use as a therapeutic agent. Other tumor-avid radiopharmaceutical agents such as 90Y- or 131I-labeled B-cell antibodies can produce regression of lymphoma when given in therapeutic doses,2 and a potential exists for the same approach with tumor-avid positron-emitting compounds such as 18F-FDG. The initial basic-science work from the... (New England Journal of Medicine)
ev3 Inc. Announces Global Launch of New PROTEGE(R) EverFlex(TM) Self-Expanding Stent System Mar 10, 2006
March 9 /PRNewswire-FirstCall/ -- ev3 Inc. (Nasdaq: ) today announced U.S. Food and Drug Administration 510(k) clearance to market the PROTEGE EverFlex Self-Expanding Stent System for the palliative treatment of malignant neoplasms in the biliary tree. Additionally, ev3 obtained CE Mark for the PROTEGE EverFlex Self-Expanding Stent System for general use in the peripheral vasculature, including common and external iliac, subclavian and the superficial femoral artery. (PR Newswire)
Celebrex and Ilk May Help Prevent Breast Cancer Jan 31, 2006
"Despite compelling evidence that Cox-2 inhibitors have powerful anti-cancer effects, several clinical trials designed to evaluate these compounds in the chemoprevention and therapy of neoplasms have been discontinued or suspended," the authors said. " The reasons for discontinuation were concerns about the cardiovascular safety of these drugs, The study was supported by a grant from Pfizer, maker of Celebrex, and a grant from the National Cancer Institute. Primary source: BMC Cancer Source... (MedPage Today)
