Biogen Idec, Roche halt trials on treatment for lupus, rheumatoid arthritis Mar 9, 2010
and its Swiss partner AG yesterday said they halted clinical trials of a new drug being tested on patients with rheumatoid arthritis and lupus after an outside monitoring panel warned its safety risks outweighed the benefits, resulting in an unspecified number of deaths ... Both treat rheumatoid arthritis, an autoimmune disease that leads to inflammation of the joints, and lupus, another chronic inflammatory disease. (Boston Globe)
Human Genome Sciences pays CFO severance Mar 5, 2010
David Stump, the company s executive vice president of research and development who oversaw the lupus drug trials that performed better than expected last year, will take home a $650,000 bonus this year compared with $195,000 in 2008. Barry Labinger, chief commercial officer who will take over Barabe s responsibilities in the interim, will receive a $430,000 bonus compared with $190,000 in 2008. (Washington Business Journal, DC)
Manzi, Ahearn to leave UPMC for West Penn Mar 4, 2010
Susan Manzi and Joseph Ahearn, co-founders and directors of the Lupus Center of Excellence at the , will join rival later this year, the hospital network announced on Wednesday ... Manzi is internationally regarded as a pioneer in research and care of people with lupus and related autoimmune disorders ... He is an internationally recognized expert in the causes and mechanisms of lupus and related diseases. (Pittsburgh Business Times, PA)
Health Tip: Who's a Good Candidate for LASIK? Mar 3, 2010
People who don't have chronic health problems such as diabetes, rheumatoid arthritis or lupus. People who are unhappy wearing contact lenses or glasses, and have realistic expectations of surgery results. (MEDLINEplus)
New Clues To Lupus' Link with Heart Disease Mar 2, 2010
FRIDAY, Feb. 26 (HealthDay News) -- An increase in certain types of immune system antibodies may contribute to the development of heart disease in people with active lupus, a new study finds. Lupus is an autoimmune illess in which the immune system creates antibodies that attack the body's own cells, causing widespread inflammation that results in damage to tissue and organs, including the heart, kidneys, brain, blood, skin and joints ... In this study, Australian and British researchers found... (MEDLINEplus)
Urine Protein Test Might Help Diagnose Kidney Damage from Lupus Feb 26, 2010
25, 2010) Simple urine tests for four proteins might be able to detect early kidney disease in people with lupus, researchers at UT Southwestern Medical Center have found in an animal study ... Kidney disease is the major cause of death and disability in lupus patients, Dr. Mohan said ... Lupus is one of many autoimmune diseases that attack internal organs, tissues, joints and other parts of the body. (Science Daily)
Antibodies linked to cardiovascular disease increase in patients with active lupus Feb 25, 2010
A study by researchers in Australia and the United Kingdom suggests that autoantibodies to fat binding proteins significantly increase in systemic lupus erythematosus (SLE) patients with active disease ... Lupus is a chronic autoimmune disease where the immune system creates antibodies that attack an individuals' own cells, causing inflammation throughout the body ... The Lupus Foundation of America's figures are much higher, with up to 1. (EurekAlert!)
Anthera delays IPO, cuts deal size Feb 25, 2010
The company, which is led by CEO Paul Truex, is also in Phase II with a drug for acute chest syndrome associated with sickle cell disease and a lupus drug licensed from. The company has 14 employees and reported losses of $12. (San Jose Business Journal, CA)
H1N1 no longer 'unknown, evil, dark' Feb 25, 2010
His wife has lupus, an autoimmune disorder. "It was extremely frightening," said Williams, who lives in Kingwood, Texas. (CNN -- Health)
•Getting to know: Cab Morris Feb 22, 2010
The event benefits the Peyton Manning Children's Hospital at St. Vincent's, Make-A-Wish, the United Mitochondrial Disease Foundation, the Lupus Foundation of America and The Villages. $5 from each ticket will go to the charity of the buyer's choice. (The Daily Journal)
A literary pilgrimage to O’Connor’s ‘the middle of nowhere’ Feb 21, 2010
The author of Southern Gothic classics including Wise Blood and Everything That Rises Must Converge, O Connor, who never married, wrote some of her best work at Andalusia and died at 39 from lupus in 1964 ... Cline willed part ownership of the farm to O Connor s mother, and she and her daughter came to live here in 1951, after O Connor had earned her master s at the University of Iowa Writer s Workshop and had begun suffering from lupus. (Boston Globe)
Scientists Discover How Protein Trips Up Germs Feb 20, 2010
And in cases of autoimmune diseases -- arthritis, lupus and asthma, for example -- it's possible that the inhibition of TRPV2 might help pull back an overactive immune system. "We think there are going to be a lot of implications beyond just prevention of infectious diseases where this research about TRPV2's function in macrophages might be relevant," Link adds. (Science Daily)
Mark Twain Health Feb 18, 2010
On Saturday, March 27, the month-long series' last day will begin at 8:30 a.m. with a five-mile walk/run Lupus Awareness Race held in memory of Linda Jean Mundy. The evening will come to an end with a barn dance at Hay Station Ranch on Six Mile Road. (San Andreas Calaveras Enterprise, CA)
First lupus awareness week starts Feb 17, 2010
The first Lupus and Sickle Cell Anemia Awareness Week will be held from Tuesday to Saturday. The week was designed to raise awareness about lupus and sickle cell anemia on campus, said Tierra LeGrand, president of the National Association for the Advancement of Colored People ... They will be selling lupus and sickle cell anemia wrist bands and lupus butterflies, a symbol of the Lupus Foundation of America. (Daily Orange, NY)
For coyotes, at least, study finds New Englanders a special breed Feb 17, 2010
The service protects the gray wolf (Canis lupus) and the red wolf of the Southeastern United States (Canis rufus) under the Endangered Species Act ... Amaral said that because Eastern wolves hybridize with coyotes to the south and with gray wolves to the west, you cannot draw hard lines on a map and say these are lycaon and these are lupus and these are latrans. (Boston Globe)
A Man with Arthralgias, Oral Ulcers, Vision Loss, and Vocal-Cord Paralysis Feb 11, 2010
Systemic Lupus Erythematosus and Rheumatoid Arthritis. Beh;et's Syndrome. (New England Journal of Medicine)
Women's Lacrosse Team Raising Awareness for Lupus with "Lacrosse for Lupus" Feb 11, 2010
Brown Bears: Women's Lacrosse Team Raising Awareness for Lupus with "Lacrosse for Lupus" ... Women's Lacrosse Team Raising Awareness for Lupus with "Lacrosse for Lupus" ... PROVIDENCE, RI - The Brown women's lacrosse team, which will sponsor several service projects throughout the year, has plans for a major fundraising initiative to benefit the Lupus Foundation. (Brownbears.com)
Port Orange woman with medical condition missing Feb 6, 2010
Laurel Lea Rogers, who has the auto-immune disease lupus and is in jeopardy of complete organ failure without her medication, hasn't been seen since Monday evening, her mother and Port Orange police say. Rogers is under the care of a nephrologist because her disease has affected her kidneys. (Daytona Beach News Journal -- Local)
Faried's rebounds carry special meaning Feb 5, 2010
"He was trying to get to 20," said Waudda Faried, who monitors her son's progress while battling lupus from her home in Newark, N.J. "I told him I want 30." ... " Simmons said. Chairmen of the boards Here's a look at the top 10 rebounders in the nation through Tuesday's games. NameSchoolAverage Kenneth FariedMorehead State13.7 Artsiom ParakhouskiRadford13.2 Damian SaundersDuquesne12.5 Kevin ThompsonMorgan State12.4 Daniel EmersonMercer11.9 Al-Farouq AminuWake Forest11.2 Herb PopeSeton Hall11.2... (Notre Dame Sports -- Rivals.com)
Kemal Gordon, 29; wrote film that captured city pulse Feb 5, 2010
Mr. Gordon, who wrote, directed, and completed his first and only film while undergoing dialysis treatment, died Sunday in Brigham and Women s Hospital of complications of lupus ... While attending the school, he was diagnosed with lupus nephritis, a kidney disorder that is a complication of systemic lupus, an immune system disease. (Boston Globe)
Project to develop Adrian's Island passes 9-1 Feb 5, 2010
joytotheworld wrote on Feb 4, 2010 7:16 AM:" ...and fish for hookers if they float past Lupus. ". boscoe wrote on Feb 3, 2010 2:50 PM:" Watch the dead bodies float down the river...Gar fishing... ". (Jefferson City News Tribune, MO)
Another wolf pack in sights (2069) Feb 4, 2010
" Canis lupus irremotus is the wolf that is/was prevalent to the Rocky Mountains. Canis lupus griseoalbus, the larger cousin from Alberta was introduced into Yellowstone park. Basically, a super-predator invasive was introduced. Hence the explosion of wolf numbers and drastic decline in elk numbers."The wolves have been around here fore eons keeping the eco-system clean, knocking down the sick and diseased animals and keeping the herds healthy. " (I won't copy the whole run-on sentence because... (Montana Standard, MT)
Fewer Childhood Deaths from Rheumatic Disease Feb 3, 2010
The risk of death was notably greater for children with systemic lupus erythematosus and dermatomyositis, but not for systemic juvenile rheumatoid arthritis. The risk of death was markedly less for children with pain syndromes. (MEDLINEplus)
Dogs May Provide an Excellent Model for Understanding Human Complex Diseases Feb 3, 2010
Veterinarian Helene Hamlin at SLU has previously described an autoimmune disease complex in the breed Nova Scotia duck tolling retriever, which is characterized by a rheumatic SLE-like disorder (Systemic Lupus Erythematosus), where the dog develops joint complaints and inflammatory symptoms in various inner organs. In these, the body has often formed antibodies against the nuclei of the body's own cells, a characteristic found in SLE in humans as well. (Science Daily)
Click to read: Hubby Wanted -- For Health Care Feb 2, 2010
"[It] makes me unable to process bacteria and viruses efficiently and my body attacks itself. It's very similar to lupus," she explained. As a mother and housewife for 24 years, Carlson never had to worry about health care, until now. (CBS News -- Early Show)
Lyme Disease: It may be "under your skin" (3) Feb 1, 2010
Wilson said the problem with the disease is that it mimics other diseases, including fibromyalgia, chronic fatigue, lupus, RA, autism, MS, Parkinson s and ALS.. I was shocked at what Lyme could do, he said. (Catskill Daily Mail, NY)
New Therapeutic Approach Identified for Kidney Disease Associated With Lupus Feb 1, 2010
31, 2010) Investigators have identified a new disease mechanism and therapeutic approach for a type of advanced kidney disease that is a common cause of complications in patients with lupus ... "The standard treatment for lupus kidney disease is to block inflammation," said Lionel Ivashkiv, M.D., associate chief scientific officer at Hospital for Special Surgery in New York City ... For years, clinicians have known that kidney damage occurs in many patients with lupus, and they have known how... (Science Daily)
Blood test may predict rheumatoid arthritis Jan 30, 2010
They reflect "general immune system activation," he explains, and could indicate a host of other inflammatory autoimmune diseases (such as lupus or psoriasis), or even a viral infection. Still, he says, "It is exciting to think that...we could be alerted to the fact that [people] may go on to develop RA or another autoimmune disease.". (CNN -- Health)
Biomarker could help doctors tailor treatment for rheumatoid arthritis Jan 30, 2010
"While our study was performed on a relatively small group of patients and will need to be confirmed in a larger cohort, the data are promising and may be clinically significant for the medical management of patients," said Mary K. Crow, M.D., director of Rheumatology Research and co-director of the Mary Kirkland Center for Lupus Research at Hospital for Special Surgery ... Dr. Crow's work was supported by a grant from the National Institutes of Health, the Alliance for Lupus Research, the Lupus... (EurekAlert!)
Run for the Roses Jan 29, 2010
McIntire suggested the Lupus Foundation. I choose the Lupus Foundation because someone close to me has the disease and I was trying to help them in any way I can, he said. (McKinney Courier-Gazette, TX)
Vista Woman Will Marry For Health Coverage Jan 29, 2010
"It makes me unable to process bacteria and viruses efficiently, and my body attacks itself. It's very similar to Lupus," Carlson told 10News. In one of her videos, Carlson said, "Desperate times call for desperate measures.". (TheSanDiegoChannel.com, CA)
Transverse Myelitis Jan 28, 2010
Lupus- An autoimmune disease that causes the immune system to attack the body. Sjogren's syndrome. (Suite101.com)
Arthritis: Environmental Exposure to Hairspray, Lipstick, Pollution, Can Trigger Autoimmune Diseases Jan 28, 2010
Why are people who live near airports more susceptible to autoimmune diseases like rheumatoid arthritis and lupus ... And some medications, such as the birth control pills, might be linked in some cases to the onset of lupus. (Science Daily)
Blood test can predict rheumatoid arthritis before symptoms arise Jan 28, 2010
Many diseases including lupus, osteoarthritis and fibromyalgia, especially early on, mimic the symptoms of RA making diagnosis more difficult. Studies have shown that people who receive early treatment for RA feel better sooner and more often, are more likely to lead an active life, and are less likely to experience the type of joint damage that leads to joint replacement. (EurekAlert!)
Mortality rates for pediatric rheumatology patients significantly lower than previously reported Jan 28, 2010
While rheumatic diseases present well-known risks to health, function, and quality of life, several conditionsjuvenile rheumatoid arthritis, childhood systemic lupus erythematosus, dermatomyositis, various vasculitides, and systemic sclerosis are associated in various studies with a small but significant increase in mortality ... The standardized mortality ratio was notably greater for systemic lupus erythematosus and dermatomyositis but not for systemic juvenile rheumatoid arthritis and was... (EurekAlert!)
Malaria Meds Cut Lupus Death Rate Jan 26, 2010
Drugs used to treat malaria may be useful for patients with lupus, a chronic debilitating "autoimmune" disease, according to according to a new report. In fact, the authors of the study, in the journal Arthritis and Rheumatism, recommend that doctors give the drugs to all patients with lupus ... Lupus is a chronic disease in which the immune system confuses its own healthy tissues with foreign tissues and sometimes attacks both. (Newsmax)
Study says genetics, not environment, may be cause of S. Boston scleroderma cluster Jan 25, 2010
The study found that people with a family history of specific autoimmune-rheumatic diseases, such as rheumatoid arthritis, Raynaud s disease, lupus, and thyroid disease, were more likely to develop scleroderma ... More studies in the immediate future appear unlikely, though state researchers are encouraging present and past South Boston residents with scleroderma or lupus to participate in a national registry designed to identify a genetic link. (Boston Globe)
Jessie Elizabeth Proctor (9) Jan 25, 2010
Memorials may be made to the Community Hospice, The American Cancer Society or to the Lupus Foundation. For directions or to send an online condolence, visit. (Hudson Register Star, NY)
Experts call for greater obesity awareness Jan 24, 2010
She also has lupus, which attacks her joints, and she hopes losing weight will mean less strain on her joints and help her avoid knee-replacement surgery. She knows it will not happen overnight and thinks she will hit her goal weight by February of next year -- just by doing things the right way. (The Augusta Chronicle)
Developments in osteoarthritis, fibromyalgia Jan 24, 2010
"Get sufficient sleep and exercise, take your prescribed medication and pain medication when needed. Understand the disease. It's important to know nothing bad will happen to your joints. You won't become crippled, deformed or develop problems with your internal organs as you could with rheumatoid arthritis and/or systemic lupus erythematosus.". Comments. (Shelby Twp Advisor & Source, MI)
Boeing Classic has new charity beneficiary Jan 23, 2010
The Benaroya Research Institute was established in 1956 as the and today researches autoimmune diseases such as arthritis, diabetes, lupus, multiple sclerosis and scleroderma. The Boeing Classic is part of the Champions Tour, in which golf pros 50 years old and older compete. (Puget Sound Business Journal, WA)
Family crusades against disease Jan 19, 2010
Unfortunately because of a flawed set of guidelines, doctors are not looking for this and are diagnosing many people with the following syndromes that have no cure: MS (Wilson was diagnosed with MS his freshman year when he was just 15); chronic fatigue syndrome (Shelbys prior diagnosis), lupus, fibromyalgia (with this, you are going to feel as if you have the flu the rest of your life, on pain meds, this is a horrible diagnosis); ALS, Bells palsy, the list goes on. . (West Memphis Germantown News, TN)
Disabled worshippers struggle as many churches lack access Jan 16, 2010
"(Churches) can't imagine how many people are sitting at home wanting to come but can't," said Bulloch, a lupus patient who said she often wants to visit other churches, but can't get inside them. For some, there are still spiritual barriers more ingrained than the physical ones. (USA Today -- News)
Doctors puzzle over womans mystery ailment Jan 15, 2010
Doctors puzzle over womans mystery ailment - TODAY Health. Doctors puzzle over womans mystery ailment. (MSNBC -- Health)
GlaxoSmithKline to Seek U.S. Backing for Lupus Drug in First Half of 2010 Jan 13, 2010
Glaxo to Seek U.S. Approval for Lupus Drug This Year (Update1) - Bloomberg ... Glaxo to Seek U.S. Approval for Lupus Drug This Year (Update1) ... Jan. 12 (Bloomberg) -- will seek U.S. approval of its experimental lupus drug, Benlysta, in the first half of the year, Chief Executive Officer said. (Bloomberg -- UK)
Human Genome Sciences gives 2010 forecasts Jan 12, 2010
In the second quarter of this year, the Rockville biotech said it plans to submit its application to U.S. and European regulators to start selling Benlysta, a lupus treatment that scored unexpectedly positive data in clinical trials last year ... If that occurs, Benlysta would be the first lupus treatment to enter the market in decades, a commercial prospect that s led to a of the local company, opened up a potential billions-dollar market and shot its shares up to 14 times their value from New... (Washington Business Journal, DC)
Scientists decode secrets of dog breeding Jan 12, 2010
Genes for different breedsDogs (Canis lupus familiaris) were around 14,000 years ago, long before the field of genetics even existed, though most dog breeds were developed in the last few centuries. As humans bred dogs for features such as shorter legs or a docile temperament, they were actually tinkering with genes, while influencing the selection and expression of dog genes. (MSNBC -- Environment)
Health Tip: Why People Lose Their Hair Jan 10, 2010
An underlying disease, such as diabetes or lupus. HealthDay. (MEDLINEplus)
Health Tip: What Could Be Causing Renal Failure Jan 10, 2010
The autoimmune disease lupus. A lingering blockage in the urinary tract. (MEDLINEplus)
Cross-donor system planned for region's kidney patients Jan 10, 2010
had wanted to donate a kidney to her husband, Rosario, whose kidneys were gradually failing as a result of a long battle with lupus. But both her blood and tissue types were a complete mismatch for him, so Rosario remained on a transplant waiting list for years, relying on home dialysis to keep his body going. (Yahoo News -- Organ Donation & Transplants)
Health Tip: Risk Factors for Carpal Tunnel Syndrome Jan 10, 2010
Certain medical problems, including rheumatoid arthritis, diabetes, hypothyroidism or lupus. HealthDay. (MEDLINEplus)
Twins Provide Clues to Lupus Jan 10, 2010
MONDAY, Dec. 28 (HealthDay News) -- Cellular changes caused by environmental factors such as diet and chemical exposure may play a role in the autoimmune disease lupus, a new study suggests. American and Spanish researchers compared the DNA of identical twins to look for epigenetic modifications (cellular changes that can influence the expression of genes) in healthy twins and twins with lupus ... Twins with lupus were found to have widespread changes in a specific epigenetic modification called... (MEDLINEplus)
Scientists Find New Key to Lupus Jan 10, 2010
MONDAY, Oct. 19 (HealthDay News) -- Researchers say they've gained new understanding of how lupus develops in mice, a finding that could help future treatments for the autoimmune disease ... 5 million to 2 million people in the United States suffer from lupus, a disorder in which the body's defenses turn inward ... "Just like in mice, in humans, if you don't clear the dying cells, then that predisposes you to lupus," said Lata Mukundan, a Stanford University School of Medicine researcher and... (MEDLINEplus)
Micro RNAs Can Turn Genes Off Jan 10, 2010
11, 2006) A Wake Forest University School of Medicine team believes it has found biomarkers for lupus that also may play a role in causing the. . (Science Daily)
Household Insecticides May Be Linked to Autoimmune Diseases Jan 10, 2010
Study suggests a connection with lupus, rheumatoid arthritis ... MONDAY, Oct. 19 (HealthDay News) -- New research suggests a link between women's exposure to household insecticides -- including roach and mosquito killers -- and the autoimmune disorders rheumatoid arthritis and lupus ... Previous research has linked agricultural pesticides to higher risk of rheumatoid arthritis and lupus, two diseases in which the immune system goes haywire and begins to attack the body. (MEDLINEplus)
Lupus Linked to Heart Disease Jan 10, 2010
NEW YORK (Reuters Health) - People with systemic lupus erythematosus (SLE) have a more than twofold increased risk of cardiovascular disease, according to a new study. Lupus is a chronic "autoimmune" disease in which the immune system confuses its own healthy tissues with foreign tissues and sometimes attacks both ... "Despite improved life expectancy in the past few decades," increased heart-related illness and death among people with lupus has been documented in several studies, Dr. A.... (MEDLINEplus)
Better Drug Emerges for Steroid-Induced Bone Loss Jan 10, 2010
Glucocorticoids are steroid hormones produced in the body or contained in drugs that are used to control inflammation in patients with autoimmune diseases, such as rheumatoid arthritis, lupus and Crohn's disease, as well as inflammatory conditions such as asthma. Glucocorticoid-induced osteoporosis can occur in people taking steroid medications such as prednisone, prednisolone, dexamethasone and cortisone, according to background information provided in a news release about the study. (MEDLINEplus)
Health Tip: Managing Lupus Symptoms Jan 10, 2010
(HealthDay News) -- Lupus is an autoimmune disease that can cause symptoms including pain and stiffness in the joints, body aches, fever, a rash on the skin and impaired cognitive function. The National Women's Health Information Center offers these suggestions to help control lupus symptoms. (MEDLINEplus)
Is Thinning Hair in Your Future? Jan 10, 2010
When I brought up my hair issue at an annual physical, my doctor tested me for lupus. Fortunately, the tests came back negative. (Marie Claire, US)
