Scientists Reach Stem Cell Milestone Aug 3, 2008
Led by Kevin Eggan at the Harvard Stem Cell Institute and Christopher Henderson at Columbia University, the 13-person team reported online today in Science Express that they had generated motor neurons from the skin cells of two elderly patients with a rare form of ALS, or Lou Gehrig's disease, a progressive neurodegenerative condition. The new study marks an important first step on the road toward real stem-cell-based therapies, and also answers several plaguing questions about the pioneering... (Time.com)
Nerve cells from new-style stem cells Aug 2, 2008
They transformed the cells from two patients with amyotrophic lateral sclerosis, or Lou Gehrig's disease, into motor neurons - the cells that waste away and die in ALS. There is no immediate medical use for the cells, taken from two sisters aged 82 and 89, the researchers reported in the journal Science ... There is no cure for ALS, also called motor neuron disease or Lou Gehrig's disease after the New York Yankees baseball player who died of it in 1941. (India Times, India)
More of this story Aug 2, 2008
Less than one year ago Keith Shiver could step out of his truck and walk through the front door of his home in Gantt to receive a loving greeting from his 3-year-old son, Luke, but now, after being diagnosed with Lou Gehrig's disease, even the smallest tasks have become the biggest challenges ... "First he started to have really bad muscle twitches and his muscles gradually wore down. His muscle spasms have just about quit now. Some days he does well and other days are not so good."He was... (Andalusia Star News, AL)
ALS patients' skin cells converted to motor neurons Aug 2, 2008
BEIJING, Aug. 1 (Xinhuanet) -- Scientists have found a way to change skin cells from patients with Lou Gehrig's disease into motor neurons that are genetically identical to the patients' own neurons, giving them an unlimited number of these neurons for study in the laboratory ... is if you could produce the cell types that become sick in that person, you might be able to use them in the laboratory to come to understand basic aspects of the disease and take the study of disease out of patients,... (Xinhuanet, China)
Scientists report a breakthrough in stem cell production Aug 1, 2008
The work was done with patients suffering from ALS, or Lou Gehrig's disease, but the researchers said the same technique can be used to study many other genetic diseases. By comparing diseased cells to normal cells in a Petri dish, scientists hope to better understand what causes disease and test new drugs. (Boston Globe)
Dying 'Dr. Death' Has Second Thoughts About Assisting Suicides Aug 1, 2008
One assisted suicide -- the death of Lou Gehrig's disease patient Thomas Youk, which was taped and broadcast on "60 Minutes" in 1998 -- earned him a prison sentence of 15 years to 20 years for second degree murder. "He did what he did, and it brought it to public awareness [of physician-assisted suicide]," said Kevorkian's attorney, Mayer Morganroth. (Yahoo News -- Assisted Suicide & Euthanasia)
Scientists Turn Skin Cells Into Motor Neurons in ALS Patients Aug 1, 2008
THURSDAY, July 31 (HealthDay News) -- Scientists have turned skin cells from patients with Lou Gehrig's disease into motor neurons that are genetically identical to the patients' own neurons ... Lou Gehrig's disease or ALS (amyotrophic lateral sclerosis) is caused by the degeneration and death of spinal motor neurons, which carry messages from the spinal cord to the body's muscles. (U.S. News & World Report)
Stem Cell Technology: First Neurons Created From ALS Patient's Skin Cells Aug 1, 2008
1, 2008) Harvard and Columbia scientists have for the first time used a new technique to transform an ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease) patient's skin cells into motor neurons, a process that may be used in the future to create tailor-made cells to treat the debilitating disease ... 24, 2007) Researchers have discovered that when motor neurons damaged by amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, inappropriately send the wrong signal, immune cells... (Science Daily)
Event to raise money for brewer suffering from Lou Gehrigs disease Aug 1, 2008
ALS, often referred to as Lou Gehrig's disease, is a progressive neurodegenerative disease that affects the body s motor neurons and results in the inability to initiate and control muscle movement. Symptoms include loss of speech, inability to swallow or breathe on one s own, and ultimately, in the later stages of the disease, total paralysis. (Cambridge Chronicle, MA)
Scientists create first personalized stem cells in ALS patients Aug 1, 2008
The researchers then converted some of those stem cells into the two kinds of brain cells that cause their crippling disease, amyotrophic lateral sclerosis, commonly known as Lou Gehrig's disease. Stem cell experts said they were delighted -- though not surprised -- to see proof that the reprogramming technique worked on human cells from sick patients. (Los Angeles Times)
'APPLE PIE' PORK Jul 31, 2008
He also accused the Republicans of voting against victims of stroke, Lou Gehrig's disease, postpartum depression and child pornography. "I have never been a bully," Reid insisted while caricaturing his opponents as cripple-kickers, mother-haters and molester-lovers. (New York Post -- Opinions)
Protein Plays Jekyll And Hyde Role In Lou Gehrig's Disease Jul 31, 2008
ScienceDaily (July 30, 2008) Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease, is a fatal neurodegenerative disease caused by the death of motor neurons in the brain and spinal cord that control muscle movements from walking and swallowing to breathing ... (May 30, 2007) Researchers have discovered a new cellular mechanism that may better explain what causes amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease ... 6, 2006) Scientists funded by... (Science Daily)
The Obstinate Obstetrician Jul 30, 2008
He also accused the Republicans of voting against victims of stroke, Lou Gehrig's disease, postpartum depression and child pornography. "I have never been a bully," Reid insisted while caricaturing his opponents as cripple kickers, mother haters and molester lovers. (Townhall.com)
Joanna Rotberg, at 73; fought ALS while focusing on teaching Jul 29, 2008
Joanna (Henshaw) Rotberg had bested the odds by surviving amyotrophic lateral sclerosis, or Lou Gehrig's disease, for 16 years when the life expectancy after diagnosis is typically three to five years. Then, in 2006, she received the even-rarer diagnosis of mesothelioma, a form of lung cancer. (Boston Globe)
Dying 'Dr. Death' Has Second Thoughts About Assisting Suicides Jul 29, 2008
One assisted suicide -- the death of Lou Gehrig's disease patient Thomas Youk, which was taped and broadcast on "60 Minutes" in 1998 -- earned him a prison sentence of 15 years to 20 years for second degree murder. "He did what he did, and it brought it to public awareness [of physician-assisted suicide]," said Kevorkian's attorney, Mayer Morganroth. (Yahoo News -- Assisted Suicide & Euthanasia)
July 27-Aug. 1 Jul 29, 2008
Shiver has been diagnosed with Lou Gehrig's disease. The price is 5 per plate and carry-out is available. (Andalusia Star News, AL)
Phillies hold Phestival against ALS Jul 29, 2008
Colby was one of about 6,000 Phillies fans who streamed through the ballpark on Monday night for the annual Phillies Phestival, an autograph party and auction created in the 1980s to strike out ALS, or "Lou Gehrig's disease." The event, now in its 19th year, raised a record-setting $758,540. Colby's photo was a shot of Utley exchanging a high-five with first baseman Ryan Howard at home plate. (MLB.com -- Philadelphia Phillies)
Scientists ID 'Jekyll-Hyde' Protein in Lou Gehrig's Disease Jul 29, 2008
TUESDAY, July 29 (HealthDay News) -- A protein dysfunction could help drive amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, according to a study by researchers at Brandeis University and Harvard Medical School. ALS is a fatal neurodegenerative disease caused by the death of motor neurons in the brain and spinal cord that control muscle movement. (Health-Finder)
Geographical Pattern Eyed in 1991 Gulf War Cases of ALS Jul 29, 2008
Of the 135 diagnosed Gulf Vet cases of ALS, also known as Lou Gehrig's Disease, in the first 11 years after the war, only three had a family history of the disease. Researchers speculate this may indicate an environmental cause. (MEDLINEplus)
Various Species' Genes Evolve To Minimize Protein Production Errors Jul 26, 2008
Misfolded proteins are known to accumulate in neurons and are central players in fatal disorders such as amyotrophic lateral sclerosis, better known as Lou Gehrig's disease. Drummond and Wilke suggest that mistranslation may contribute to long-studied forms of ALS and other similar diseases. (Science Daily)
Phillies Phestival set for Monday Jul 25, 2008
PHILADELPHIA -- On Monday, Philadelphia baseball fans will stream through Citizens Bank Park to meet Phillies players, broadcasters, coaches and the Phanatic as part of the team's annual Phillies Phestival, created to strike out ALS or Lou Gehrig's disease ... It's often referred to as "Lou Gehrig's Disease," named after the legendary Yankees first baseman who played from 1923-39. (MLB.com -- Philadelphia Phillies)
In our view: Government responsible for disease research Jul 24, 2008
We support efforts by many, including at least one local resident, to establish a national registry of people with Lou Gehrig's disease. The registry would be maintained by the respected Centers for Disease Control in Atlanta. (DeKalb Daily Chronicle, IL)
Poe: Another near miss for the Shark, but this was different Jul 23, 2008
Nick passed away last Saturday at the age of 28 after a courageous five-year battle with Lou Gehrig's disease ... "I wish to extend my deepest condolences to the family and friends of Nick Huber after he lost his courageous battle against Lou Gehrig's disease yesterday at the age of 28. Nick was a well respected and much loved member of the Buena Vista University family, and all Iowans join in grieving his loss at such an early age. Our thoughts and prayers are with his loved ones during this... (Sioux City Journal, IO)
Reid Labels New Bill Package 'Coburn Omnibus' Jul 22, 2008
Reid said the package will include the Emmitt Till Unsolved Crime Act, aimed at investigating unsolved civil rights era crimes; the Christopher and Dana Reeve Paralysis Act, a runaway and homeless youth bill; a bill to combat child exploitation by pornographers, and a measure to create a database for Lou Gehrig's disease. Many have Republican cosponsors. (Fox News)
Researchers probe geographical ties to ALS cases among 1991 Gulf War veterans Jul 22, 2008
Also known as Lou Gehrig's Disease because it crippled and ultimately killed that baseball great in 1941, ALS causes cellular degeneration in the central nervous system. Its cause is unknown. (EurekAlert!)
Patient seeks ALS database Jul 21, 2008
They don't say out loud what will happen, but as amyotrophic lateral sclerosis also known as Lou Gehrig's disease continues its deadly progression, Schmehl could die within two to five years. Lou Gehrig's is a horrible disease that attacks the nerves and muscles, causing total paralysis and death in a short time, Schmehl, 65, said. (DeKalb Daily Chronicle, IL)
Video: Allen Institute for Brain Science Unveils World's First Genome-Wide Spinal Cord Atlas Jul 18, 2008
From disabled veterans to those afflicted with Lou Gehrig's disease (ALS) or Spinal Muscular Atrophy, spinal cord related diseases and disorders affect people of all ages. Nearly one-quarter of a million Americans -- including several thousand troops in Iraq -- have suffered or suffer from a spinal cord injury; as many as 30,000 Americans suffer from ALS at any given time; and multiple sclerosis affects 2. (PR Newswire)
Stephen Hawking is staying put, Cambridge says Jul 18, 2008
The University of Cambridge has poured cold water on reports its most famous physicist might be coming to Canada to work, saying Wednesday Stephen Hawking "has no plans" to leave. A report in the Daily Telegraph in the U.K. said Hawking was contemplating joining his colleague Neil Turok at Waterloo, Ont. (CBC.ca)
Hawking visit 'single trip,' not relocation Jul 18, 2008
"It will be a fairly short trip. It is something that has been blown out of proportion," said Mr. Blackburn, who accompanies the 66-year-old scientist when he travels and assists him with the technology he uses to overcome the physical limitations placed on him by Lou Gehrig's disease. Asked if the initial trip could lead to a longer stay, Mr. Blackburn said: "Nothing is impossible, but at the moment it is a single trip.". (Globe and Mail)
New genetic map of mouse spine 'incredibly important' to scientists Jul 18, 2008
By Steve Sternberg, USA TODAY Scientists exploring the blasted terrain of nerves that give rise to crippling ailments like Lou Gehrig's disease now have an atlas to guide them ... When the system breaks down, and people develop Lou Gehrig's disease, also known as amyotropic lateral sclerosis, Parkinson's disease, Alzheimer's, multiple sclerosis or any one of many other neuromuscular diseases, genes are likely involved. (USA Today -- Tech)
New Yorkers try to swallow calorie sticker shock Jul 17, 2008
She has written for The New York Times, The Washington Post, Newsday and Real Simple magazine, among other publications, and is author of the book, "Six Parts Love: A Family's Battle with Lou Gehrig's Disease." She teaches journalism at the Columbia University Graduate School of Journalism. 2008 MSNBC Interactive. (MSNBC -- Health)
12 comments Jul 15, 2008
One of them is a bill overwhelmingly approved by the House of Representatives, which would give the CDC the ability to collect data on ALS (Lou Gehrig's disease). The ALS Registry Act would support research in finding a cure and passed 411-3 in the House. (Human Events Online)
Researchers link Huntington's disease to overactive immune response in the brain Jul 15, 2008
The UW team, lead by Dr. Thomas Moeller, research associate professor of neurology, had previously studied the role of inflammation and immune response in neurodegenerative diseases like Huntington's and ALS, also known as Lou Gehrig's disease. In this study, they found that patients with Huntington's had higher levels of immune-system signaling molecules, called cytokines, in their brain tissue. (EurekAlert!)
Taking a Chance: Harrington set for stem cell treatment Jul 13, 2008
They give similar injection treatments to patients with everything from Parkinson's Disease and Lou Gehrig's Disease to paralysis, cerebral palsy and brain damage like Tim's. I don't agree with cloning or any of that, Bryan said. (DeKalb Daily Chronicle, IL)
Goodall never gave up fight with ALS Jul 13, 2008
But until Thursday, when he died after a two-year struggle with Lou Gehrig's disease, neither his mind nor his heart ever did ... Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, slowly causes degeneration throughout the brain and spinal cord. (The St. Augustine Record)
Zilbersmith battles ALS with humor Jul 13, 2008
"For those of you who don't know, I was diagnosed with Lou Gehrig's disease a couple of weeks ago," Zilbersmith said. "Which sucks. Because I hate baseball.". (San Francisco Chronicle)
Wife Stays Strong After Husband Dies Of Lou Gehrig's Disease Jul 13, 2008
Kenny Goodall lost his battle with Lou Gehrig's disease Thursday night, just over a month after the community rallied to help him and his family. His wife, Karen, said the fact that she knew it was coming doesn't diminish the pain of his death. (News4Jax.com, FL)
Michigan Ballot To Include 'Dr. Death' Jul 13, 2008
Kevorkian, 80, also known as "Dr. Death," claims to have helped at least 130 people die from 1990 to 1998, the year he was charged with the death of a 52-year-old Oakland County man with Lou Gehrig's disease. He served eight years in prison and got out early for good behavior. (Click2Houston, TX)
ALS victim: Determined to make a memory Jul 13, 2008
ALS or Lou Gehrig's disease has since destroyed the muscles that once allowed her to walk, breathe without assistance, feed herself or speak clearly. Needless to say, ALS has taken a lot from her. (Florida Times-Union)
Community news Jul 8, 2008
The Down East ALS Support Group (Lou Gehrig's disease) will meet at 2 p.m. July 20 in the Rehab Center at Pitt County Memorial Hospital. For more information, call Linda or Lewis Forrest at 746-4221 or 746-2778. (The Daily Reflector)
ClubCorp to Repeat World's Largest One-Day Golf and Dining Event Jul 8, 2008
-- The Muscular Dystrophy Association (MDA), specifically "Augie's Quest," an initiative within MDA that is an aggressive, cure-driven effort singularly focused on treatments and cures for ALS, (amyotrophic lateral sclerosis, or Lou Gehrig's disease) ... Augie's Quest is an aggressive, cure-driven effort singularly focused on treatments and cures for amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease. (Yahoo! Wire -- Entertainment News)
Vasogen halts spending on series of drugs Jul 3, 2008
Vasogen Inc. is halting spending on a series of drugs including one aimed at Lou Gehrig's disease as it struggles to preserve cash while exploring strategic alternatives. The drug developer, whose stock price has fallen 90 per cent in the past year, put itself on the block in April and announced it was cutting its work force by 85 per cent, leaving 15 employees. (Globe and Mail -- Business)
Stem Cells Are Where It's At Jul 2, 2008
Burt also plans trials for two diseases in which "nothing else really seems to work": Lou Gehrig's disease and a rare type of autism involving the immune system. He will treat his first autism patient in January. (Newsweek)
A Boston pioneer and his mark Jul 1, 2008
Atkins, who ran unsuccessfully for mayor of Boston in 1971, spent the latter part of his career in New York City, where he fought his own battle against Lou Gehrig's disease. His time in Boston was relatively short, but leaves a deep impression. (Boston Globe)
Civil rights trailblazer Atkins dies at 69 Jun 29, 2008
Mr. Atkins died Friday night at a nursing home in Brooklyn, N.Y., after struggling for nearly two decades with the degenerative muscular disease Amyotrophic Lateral Sclerosis, or Lou Gehrig's disease. He was a humanist, but he also had a steely resolve. (Boston Globe)
S.D. stem cell efforts awarded $5 million total Jun 28, 2008
74 million over three years to validate a technique for inducing skin cells to become pluripotent cells and then using these cells to create models of various diseases, including ALS, or Lou Gehrig's disease, Rett syndrome and hemophilia. The second grant program involves small awards of about $50,000 that 22 multidisciplinary teams of scientists can use to hold meetings and formulate plans for how they would jointly use their expertise to attack a specific disease. (San Diego Union-Tribune -- Business)
Sound medicine Jun 26, 2008
The long-term goal of the brain-computer interface is to enable almost conversational speech for individuals with locked-in syndromes or diseases that affect speech motor output, such as Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's Disease). Other applications of the model include stuttering, apraxia of speech, and other related disorders. (EurekAlert!)
Pearson leaves legacy of spirit, generosity Jun 25, 2008
He had suffered for years from primary lateral sclerosis, which is similar to ALS, or Lou Gehrig's disease. Visitation will take place after 11 a.m. Friday at the Warner Funeral Home in Spencer, Iowa, with the family present from 5-7 p.m.. (Sioux City Journal, IO)
Artificial turf target of legal action Jun 25, 2008
In adults, it's associated with cardiovascular disease, high blood pressure and kidney failure in those with chronic kidney disease, as well as with Lou Gehrig's disease. Caroline Cox, research director with the Center for Environmental Health, said while chromate lead does encapsulate the metal, the center's testing found some still does break out. (San Jose Mercury News)
Many ALS Patients Have High Quality Of Life, Studies Find Jun 25, 2008
(May 30, 2007) Researchers have discovered a new cellular mechanism that may better explain what causes amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease ... 31, 1997) Myotrophin, an experimental drug for Lou Gehrig's disease, appears to slow the disease's symptom. (Science Daily)
Umbilical cord blood cell transplants may help ALS patients Jun 25, 2008
Tampa, FL (June 24, 2008) A study at the University of South Florida has shown that transplants of mononuclear human umbilical cord blood (MNChUCB) cells may help patients suffering from Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. A disease in which the motor neurons in the spinal cord and brain degenerate, ALS leaves its victims with progressive muscle weakness, paralysis and, finally, respiratory failure three to five years after diagnosis. (EurekAlert!)
Now, a ray of hope for autism patients Jun 24, 2008
The disorder strikes one in 6,000 people, making it twice as common as Huntington's or Lou Gehrig's disease. Rapamycin is well-known for targeting an enzyme involved in making proteins required for memory. (India Times, India)
No fish tale: Lots of fun had at tourney Jun 24, 2008
His father died of ALS, commonly known as Lou Gehrig's Disease, and his mother was afflicted with ovarian cancer. Sue Spalding, executive director of the ALS Associate Minnesota chapter, said the exposure gained from being associated with the tournament was of great help to the cause. (MLB.com -- Minnesota Twins)
Drug reverses mental retardation caused by genetic disorder Jun 23, 2008
The disorder strikes one in 6,000 people, making it twice as common as Huntington's or Lou Gehrig's disease. Silva and Ehninger studied mice bred with TSC and verified that the animals suffered from the same severe learning difficulties as human patients. (EurekAlert!)
Fenway picnic supports Sox Scholars Jun 23, 2008
The wife of reliever Mike Timlin began her Sunday by raising money for ALS (Lou Gehrig's Disease) research through the annual "Positive Spin" cycling event in Wayland, Mass. She then waited through the rain and the 13 innings of baseball to hold an even bigger fundraiser at Fenway Park. (MLB.com -- Boston Red Sox)
CAL FIRE/Butte County Rescue to hold "Fill the Boot" Fundraiser Jun 21, 2008
More than 40 neuromuscular diseases are covered by MDA, including ALS, commonly known as Lou Gehrig's disease. MDA funds some 350 research projects by leading scientists around the world. (Gridley Herald, CA)
More of this story Jun 21, 2008
Buddies of Bob' to hold benefit for local man with Lou Gehrig's disease ... Bob Baynes of Portsmouth, who has been diagnosed with Lou Gehrig's disease, works Friday in his office at the John E. Fogarty Judicial Complex in Providence ... What: Fundraisers for Bob Baynes of Portsmouth, who has ALS, also known as Lou Gehrig's disease. (Newport Daily News, RI)
Linda Schmitt\57 Jun 20, 2008
She suffered from Lou Gehrig's Disease. She was born on May 25, 1951 at Bloomfield to Charles and Eulala Davis Roberts. (Fort Madison Daily Democrat, IO)
Biotechs now welcoming patient-advocacy funds Jun 20, 2008
The company has also received funding from Project A.L.S. in New York, for its work on a treatment for the neurodegenerative disorder known as Lou Gehrig's disease. Developing a treatment for a neurodegenerative disease is complicated, risky and expensive, but collaborating with the Fox Foundation helped Ceregene deal with all those issues, said Chief Executive Jeffrey Ostrove. (San Diego Union-Tribune -- Business)
FDA approves NeuRx diaphragm pacing system for use in spinal cord- injured patients Jun 19, 2008
A clinical trial also is underway testing DPS with patients who have Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. This incurable and fatal neuromuscular disease is characterized by progressive muscle weakness. (EurekAlert! -- Business News)
Device restores musical talent that Gehrig's disease took Jun 19, 2008
The condition commonly called Lou Gehrig's disease amyotrophic lateral sclerosis, or ALS has left Everett unable to walk, talk or breathe normally. But a device known as ERICA, for Eye Response Interface Computer Aid, uses an infrared camera to track the glint in Everett's eye so that he can manipulate software functions by moving his gaze across a computer screen. (USA Today)
Franklin Booth, member of LA Times founding family, dies Jun 18, 2008
Booth, a great-grandson of newspaper founder Gen. Harrison Gray Otis, died Sunday at his home in Los Angeles from complications of Lou Gehrig's disease, his family told the paper. During the 1950s, Booth oversaw the printing of the newspaper. (Fresno Bee -- Business)
On The Evolutionary Trail Of Molecules That Cause Lou Gehrig's Disease Jun 18, 2008
That led to work with similar proteins in the nerve cells of worms, fruit flies, and people and culminated in important clues about what goes wrong in the nerves and muscles of people with amyotrophic lateral sclerosis (better known as ALS or Lou Gehrig's disease), said Bellen, a professor molecular and human genetics at BCM. ... (May 30, 2007) Researchers have discovered a new cellular mechanism that may better explain what causes amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's... (Science Daily)
Retirement Living TV Wins Three Regional Emmy Awards Jun 18, 2008
The network's health issues program Healthline was nominated for its episode on Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease, in the Informational/Instructional -- Program/Special category and in the category of Program Host/Moderator, The Florence Henderson Show was nominated. The executive producer of What's Next. (Yahoo! Wire -- Entertainment News)
Lou Gehrig's protein found throughout brain, suggesting effects beyond motor neurons Jun 17, 2008
PHILADELPHIA - Two years ago researchers at the University of Pennsylvania School of Medicine discovered that misfolded proteins called TDP-43 accumulated in the motor areas of the brains of patients with amyotropic lateral sclerosis (ALS), or Lou Gehrig's disease. Now, the same group has shown that TDP-43 accumulates throughout the brain, suggesting ALS has broader neurological effects than previously appreciated and treatments need to take into account more than motor neuron areas. (EurekAlert!)
