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    News, Reviews, and Articles on Liver Diseases

    Archives: Liver Diseases

    Down-staged liver cancer associated with good post-transplant outcomes  Sep 5, 2008
    This report is in the September issue of Hepatology, a journal published by John Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is available online at Wiley Interscience (). (EurekAlert!)

    Normal ALT levels may mask advanced fibrosis in liver disease patients  Sep 5, 2008
    Patients with nonalcoholic fatty liver disease (NAFLD) may have normal alanine aminotransferase (ALT) levels in spite of having advanced fibrosis, according to a new study in the September issue of Hepatology, a journal published by John Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is available online at Wiley Interscience (). (EurekAlert!)

    Predicting Mortality in Cirrhosis — Serum Sodium Helps  Sep 4, 2008
    1 These success rates, together with a high prevalence of chronic liver diseases and a shortage of donors, have led to a steady increase in the number of patients awaiting liver transplantation. More than 16,000 patients in the United States are on the waiting list, and approximately 6000 liver transplantations are performed each year. (New England Journal of Medicine)

    Noninvasive test accurately identifies advanced liver disease without biopsy  Sep 1, 2008
    In the study, Dr. Chan and colleagues evaluated the accuracy of LSM to detect severe liver fibrosis in 133 patients suffering from chronic liver diseases. The research team recruited adult patients with chronic liver diseases who were clinically indicated for liver biopsy examination in a twelve-month window. (EurekAlert!)

    Accumulated Bits Of A Cell's Own DNA Can Trigger Autoimmune Disease  Aug 22, 2008
    12, 1998) Research that could point the way to more effective gene therapies for liver and other diseases was made public at The American Association for the Study of Liver Diseases 1998 Annual Meeting in. (Aug. (Science Daily)

    Senescence in liver cells is found by CSHL scientists to help limit acute tissue damage  Aug 22, 2008
    The new findings are the first to establish a specific role for cellular senescence in a non-cancer pathology, and, the CSHL team notes, suggests a new therapeutic approach that could help human patients with precursors of serious liver diseases such as cirrhosis, which is the 12th most common cause of death in the United States. Anti-cancer role of senescence provides an example. (EurekAlert!)

    Cholesterol buster  Aug 19, 2008
    Those with liver diseases should also refrain from taking XZK.. Although the results of the study are encouraging, it is advisable to take only the purified form of Chinese red yeast rice. (The Star Online, Malaysia)

    Hiroshima mayor urges nuclear ban  Aug 7, 2008
    Many have developed illnesses caused by radiation exposure, including cancer and liver diseases. "The most severely neglected have been the emotional injuries," Akiba said, in announcing the new two-year psychological study. (MSNBC -- International)

    Simple Lab Test For Bone Disease Linked To Risk Of Death In Dialysis Patients  Aug 3, 2008
    Surprisingly, this included patients without hepatitis or other liver diseases, which can also cause increased alkaline phosphatase levels; as well as patients who had normal serum liver function or normal nutritional status, reflected by normal serum albumin levels. In addition, patients whose alkaline phosphatase level increased during the first six months of the study were at higher risk of death over the subsequent two and one-half years. (Science Daily)

    Penn researchers find a new role for a 'Foxy Old Gene'  Aug 2, 2008
    Protein protects liver against accumulation of excess bile; implications for treating liver diseases. Liver cells from mice that do not express FOXA2 (Mutant mice accumulated bile salts and failed to detoxify them properly, which resulted in liver damage. (EurekAlert!)

    Weeding Out The Highs Of Medical Marijuana  Jul 16, 2008
    Speakers will report on promising studies that show improved strategies for targeting the endocannabinoid system, not only for pain relief, but also for treating other conditions, including stroke, liver diseases and, ironically, nicotine addiction and obesity. Thus, as the conference will hear, there are some disorders in which endocannabinoid release appears to be detrimental to our health, one example being obesity, which can be treated with Acomplia*, a licensed synthetic medicine that acts... (Science Daily)

    State Supreme Court Gives Swedish Green Light to Open Liver Transplant Program  Jul 13, 2008
    While some liver conditions and their complications can be treated effectively with medications, liver transplantation is now widely accepted for a variety of irreversible acute and chronic liver diseases for which there is no satisfactory therapy. Transplantation is usually appropriate for patients with: -- Advanced chronic liver disease -- Fulminant hepatic failure -- Congenital liver disorders -- Metabolic diseases -- including imbalances of iron, cholesterol, copper or enzymes -- Some liver... (PR Newswire)

    Digestive Disease Week study examined ACR's guidelines for CT colonography interpretation  Jul 13, 2008
    Jointly sponsored by the American Association for the Study of Liver Diseases, the American Gastroenterological Association (AGA) Institute, the American Society for Gastrointestinal Endoscopy and the Society for Surgery of the Alimentary Tract, DDW took place May 17-22, 2008, at the San Diego Convention Center, San Diego, Calif. The meeting showcased approximately 5,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. (EurekAlert!)

    Safer, More Efficient Medication For Hepatitis B Treatment Found  Jun 29, 2008
    Infected patients are at high risk of developing serious liver diseases such as cirrhosis and liver cancer, especially if they have high levels of HBV DNA in their blood ... 16, 2008) Lamivudine is an effective antiviral agent for treatment of patients with chronic hepatitis B and advanced liver diseases. (Science Daily)

    Safer, better medication for Hepatitis B identified  Jun 28, 2008
    Patients are likely to develop serious liver diseases like cirrhosis and liver cancer, especially if they have high levels of HB virus (HBV) DNA in their blood. . (Sify.com, India)

    Sound medicine  Jun 26, 2008
    Clinical studies using these techniques on various organs including the liver, prostate,breast and heart have demonstrated the utility of this tool, and researchers are now beginning to apply this technology for the detection of liver diseases ... Knowledge of liver stiffness enables physicians to detect and treat chronic liver diseases, when they are most treatable. (EurekAlert!)

    BUSINESS IN BRIEF  Jun 24, 2008
    She specializes in digestive and liver diseases, colonoscopy, upper endoscopy and endoscopic ultrasound. She can be reached at 541-926-6030. (Albany Democrat-Herald, OR)

    Acoustics' 08: Tigers, singers, earthquakes, buildings, caves, coveted violins, and more  Jun 13, 2008
    Knowledge of liver stiffness enables physicians to detect and treat chronic liver diseases, when they are most treatable. There's just one hitch: Current use of transient elastography is limited to average-weight adults. (EurekAlert!)

    Men's health program launched  Jun 8, 2008
    Men are three times more likely to take their own life and are more likely to die from HIV/AIDS. Men are also more likely to die from lung cancer, emphysema and liver diseases. "Men's health is too often overlooked as an issue," Ms Roxon said. (Sydney Morning Herald -- Australia)

    One glass of Wine per day keeps Liver diseases at Bay: Research  May 27, 2008
    UC San Diego School of Medicines researchers have studied wine drinkers who consumed one glass a day. On studying them, the researchers concluded that wine is safe for the liver, and also lowers the pervasiveness of Non-Alcoholic Fatty Liver Disease (NAFLD). (HealthJockey.com)

    New Hope for Liver Diseases  May 25, 2008
    That was one of several reports on advances against liver diseases that were presented this week at Digestive Disease Week 2008 in San Diego ... For more on liver diseases, go to. (Health-Finder)

    Liver cirrhosis, other liver diseases, and risk of hospitalisation for intracerebral haemorrhage: A Danish population-based case-control study  May 25, 2008
    Liver diseases are suspected risk factors for intracerebral haemorrhage (ICH). We conducted a population-based case-control study to examine risk of ICH among hospitalised patients with liver cirrhosis and other liver diseases ... Among cases and controls we identified patients with a discharge diagnosis of liver cirrhosis or other liver diseases before the date of ICH. We computed odds ratios for ICH by conditional logistic regressions, adjusting for a number of confounding factors. (BioMed Central)

    Radiofrequency ablation is effective treatment for dysplasia in Barrett's esophagus  May 20, 2008
    Jointly sponsored by the American Association for the Study of Liver Diseases, the American Gastroenterological Association (AGA) Institute, the American Society for Gastrointestinal Endoscopy and the Society for Surgery of the Alimentary Tract, DDW takes place May 17-22, 2008, at the San Diego Convention Center, San Diego, CA. The meeting showcases approximately 5,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. For more information, visit. (EurekAlert!)

    New treatment for hepatitis C  May 18, 2008
    This research is the first to demonstrate the antiviral activity of Fluvastatin in human beings infected with hepatitis C, most of whom were non-responders to the standard of care treatment, said Ted Bader, M.D., the principle investigator on the project and the director of liver diseases at the OU Health Sciences Center. Since Fluvastatin will not completely clear the hepatitis C virus by itself, researchers have started a phase II randomized, controlled trial that combines Fluvastatin with... (Hindu)

    Statin Drug Used To Lower Cholesterol Effective For Hepatitis C Treatment, Study Shows  May 16, 2008
    This research is the first to demonstrate the antiviral activity of Fluvastatin in human beings infected with hepatitis C, most of whom were non-responders to the standard of care treatment, said Ted Bader, M.D., the principle investigator on the project and the director of liver diseases at the OU Health Sciences Center. Since Fluvastatin will not completely clear the hepatitis C virus by itself, researchers have started a phase II randomized, controlled trial that combines Fluvastatin with the... (Science Daily)

    1 dies, 1 ill after receiving kidneys  May 13, 2008
    He had been tested for the AIDS virus, the liver diseases hepatitis B and C, and other diseases regularly checked by the New England Organ Bank, the region's organ procurement agency. There was no evidence of worrisome infections. (Boston Globe)

    Seven vaccines you need right now  May 9, 2008
    Each year, more than 78,000 Americans become infected and about 5,000 die of associated liver diseases, including cancer, yet few know that the CDC recommends the vaccine for all sexually active people who are not in long-term relationships. Share this on. (CNN -- Health)

    Treating Fibrosis  May 5, 2008
    Scleroderma, autoimmune liver diseases, pretibial myxedema, thyroid and other conditions are often complicated by fibrosis. Learn the latest treatment news. (Suite101.com)

    Israel treats sick Gazans  May 2, 2008
    "Most are extremely ill, a lot have bullet wounds, but we also treat Palestinians with cancer, kidney and liver diseases who can't get treatment in Gaza.". He says doctors never ask patients how they got their injuries or if they belong to a militant group. (BBC News -- Africa)

    Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008  Apr 23, 2008
    The patients treated with nitazoxanide experienced no more side effects than patients who received the SOC. Interim results of this trial were presented at the 58th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in Boston, MA.(1) -- A poster presentation, titled "Evaluation of a 4-week Lead-in Phase With Nitazoxanide Prior to Nitazoxanide+Peginterferon in Treating Chronic Hepatitis C," demonstrated that reducing a nitazoxanide lead-in phase from 12 to 4 weeks,... (PR Newswire)

    Raptor Pharmaceuticals Corp. Initiates Phase IIa Clinical Study for Convivia(TM)  Apr 21, 2008
    Although the risks of cancers and other health problems associated with this disorder have been documented in numerous studies over the past several years, they are not widely known to the general population or to the substantial proportion of Asians who are at risk. Even light to moderate ethanol intake may expose people with this condition to increased risks for serious diseases without them realizing it. (Canada Newswire)

    Father and son will run Marathon for liver charity  Apr 18, 2008
    RFR money raised goes to research, education and advocacy for more than 100 types of liver diseases, including hepatitis. On April 21, winter training will be a dim memory as these runners tackle one of the most difficult races in the world. (Winchester Star, MA, MA)

    Slightly Abnormal Blood Test May Point To A 'Silent' Form Of Hepatitis B  Apr 16, 2008
    In the first study to screen for multiple markers of hepatitis A, B and C in more than 100 patients entering an opiate-addiction treatment program, researchers at Rockefeller University were able to look at the coinfection of these liver diseases and reveal a startling fact: that a high percentage of recovering injection-drug users who had hepatitis B in the past are still infected with hepatitis B DNA in the absence of actively replicating virus. This report, led by Mary Jeanne Kreek, head of... (Science Daily)

    Protests Erupt At Dalai Lama Event  Apr 15, 2008
    E-Mail News Alerts Get breaking news and daily headlines. DALAI LAMA VISITS SEATTLE. (KIRO TV, WA)

    Gabe's View: Carter's Misguided Peace Mission  Apr 15, 2008
    Get breaking news, daily headlines and more. POSTED: 6:32 pm EDT April 14, 2008UPDATED: 7:51 am EDT April 15, 2008. (WNBC.com, NY)

    Miss USA 2008 Title Goes To Texan  Apr 13, 2008
    There are two common types of inherited liver diseases. Find out if you are at risk of being affected by either hemochromatosis or alpha-1 anti-trypsin deficiency. (Click2Houston, TX)

    Dads' Early-Onset Obesity Linked to Liver Disease in Kids  Apr 5, 2008
    "This study is the first to look at the connection between parental early-onset obesity and elevated serum ALT levels in their children using objective clinical measurements of parental BMI instead of self-reports," study first author Dr. Rohit Loomba, of the Liver Diseases Branch of the U.S. National Institute of Diabetes and Digestive and Kidney Diseases, said in a prepared statement. "Though we are looking at a very specific, community-based sample in our work, the results suggest an... (MEDLINEplus)

    Early-onset Obesity In Father Linked To Increased Potential For Liver Disease In Child  Apr 4, 2008
    "This study is the first to look at the connection between parental early-onset obesity and elevated serum ALT levels in their children using objective clinical measurements of parental BMI instead of self-reports," said Rohit Loomba, MD, of NIDDK's Liver Diseases Branch and first author of the study ... Previous studies have reported that there is a familial clustering of factors that may predispose a person to the development of liver diseases. (Science Daily)

    Expert: Warming means more algae  Apr 4, 2008
    The 40 to 50 harmful species of the blue-green algae have been linked to digestive, neurological and liver diseases in humans. Municipal water plants across the United States spend millions to treat it. (News & Observer)

    Substance abuse on the rise  Feb 29, 2008
    He noted that substance abuse can lead to cancers of the body, infertility in both men and women, low birth weight in children, hypertension and liver diseases Dr Osei said it was far easier to avoid the first drink or smoke than to avoid second and subsequent ones. He advised the youth that, addiction was an almost sure way of cutting their education short or making their life not worth it. (Ghana Web, Ghana)

    Mechanisms of HBV virulence found  Feb 25, 2008
    WASHINGTON: Scientists at France's National Institute of Health and Medical Research (INSERM) have said that they have uncovered a novel molecular mechanism by which the Hepatitis B virus (HBV) causes liver diseases ... Their first exciting discovery was the inhibition of liver cell proliferation by X protein, which raised a novel mechanism on how HBV causes liver diseases. (India Times, India -- Health/Science)

    Who found some new mechanisms of HBV virulence?  Feb 23, 2008
    This discovery raised a novel mechanism on how HBV causes liver diseases. Recently, the team further investigated how X protein inhibited the liver cell proliferation. (EurekAlert!)

    Geisinger and Celera to collaborate on liver disease test  Feb 20, 2008
    The collaboration will evaluate Celeras numerous genetic findings in liver diseases, including the Cirrhosis Risk Score, in the Geisinger bank of more than 600 liver tissue and blood case-control samples donated from patients who have undergone bariatric weight loss surgery ... Understanding the natural history of NAFLD and NASH, especially identification of those patients with or at risk for NASH represents a critical unmet diagnostic need in liver disease, said Scott Friedman M.D., Fishberg... (EurekAlert! -- Business News)

    Treasury bill interest rates fall  Feb 20, 2008
    Ocera Therapeutics, a San Diego-based company developing therapies for gastrointestinal and liver diseases, said it has completed a $35. 5 million Series C financing. (San Diego Union-Tribune -- Business)

    The best of times and the worst of times: Sustaining the future of academic GI  Feb 2, 2008
    Academic GI divisions play an extremely important role in moving the field forward, but their ability to meet their educational and research missions is increasingly challenged by many political and economic factors, according to Timothy C. Wang, MD, AGAF, chair of the AGA Institute Future Trends Committee and Chief, Division of Digestive and Liver Diseases, Columbia University. GI divisions will need to adapt to the changing nature of the health care economy and capitalize on those changes to... (EurekAlert!)

    AMT's Lead Product Poised to Address Major Liver Disease  Jan 28, 2008
    Over 60 million adult Americans and an unknown proportion of children are believed to suffer from NAFLD. At the lowest range of the estimates, 11 percent of these patients develop NASH. Ronald Lorijn, CEO of AMT, said, "We are very pleased that EPO granted this important patent to AMT. This substantially widens the potential use of our lead product AMT-011 beyond the current orphan indications to the large patient populations who suffer from fatty liver diseases, hypertriglyceridemia and insulin... (PR Newswire)

    Proteomic profiling shown more accurate than traditional biomarkers in identifying liver cancer  Jan 15, 2008
    Consequently, elevated AFP levels could be indicators of not only cancer, but also of other liver diseases or even benign conditions, while on the other hand, many patients with small tumors will test negative for AFP.. The authors, therefore, decided to evaluate the sensitivy and specificity of SELDI-TOF MS for the detection of liver cancer and to compare its effectiveness with AFP.. (EurekAlert!)

    Simple Test Accurately Predicts Risk Of Serious Jaundice In Newborns  Jan 13, 2008
    22, 2006) Researchers at Cincinnati Children's Hospital Medical Center have developed the first gene chip to use in the early diagnosis of at least five hereditary liver diseases, to detect genetic causes of. (Nov. (Science Daily)

    Websense shares up on report  Jan 9, 2008
    Ocera Therapeutics, a privately held San Diego company developing therapies for gastrointestinal and liver diseases, said the Food and Drug Administration granted orphan drug status to its compound AST-120 for treatment of pouchitis. Orphan drug status is designed to encourage companies to develop therapies for diseases that have a small market by promising drugs seven years of market exclusivity. (San Diego Union-Tribune -- Business)

    Shorter HCV Treatment Shows Notable Success  Jan 8, 2008
    8, 2004) Data from two ongoing studies testing new approaches for the treatment of chronic hepatitis C will be presented at the annual meeting of the American Association for the Study of Liver Diseases. (Aug. (Science Daily)

    MRI Techniques Evolving Towards Better Assessment Of Liver Fibrosis  Jan 8, 2008
    (May 23, 2007) Two recent studies have found that magnetic resonance elastography (MRE), a new imaging technique is an accurate tool for non-invasive diagnosis of liver diseases. The liver responds to many diseases. (Science Daily)

    Effective Treatment Found For Hepatitis C Patients With Low Blood-platelet Counts, Study Suggests  Jan 6, 2008
    Dr. Sigal is assistant professor of medicine in the Division of Gastroenterology and Hepatology at Weill Cornell Medical College and assistant attending hepatologist in the Center for Liver Diseases and Transplantation at NewYork-Presbyterian/Weill Cornell. The Phase 2 placebo-controlled study followed 74 patients with low platelet counts and cirrhosis of the liver due to hepatitis C virus (HCV) infection. (Science Daily)

    Eltrombopag effective for hepatitis C patients with low blood ...  Dec 31, 2007
    Dr. Sigal is assistant professor of medicine in the Division of Gastroenterology and Hepatology at Weill Cornell Medical College and assistant attending hepatologist in the Center for Liver Diseases and Transplantation at NewYork-Presbyterian/Weill Cornell. Weather. (Hindu)

    Research Offers Promise for Cirrhosis Treatment  Dec 29, 2007
    Dr. Scott Friedman, chief of the Division of Liver Diseases at Mount Sinai School of Medicine in New York City, said that while the study is useful, it's "not a major breakthrough" considering the many research projects in a similar stage of development. Still, he said, it "builds on 20 years of very exciting research" that looks at how cells create scarring in the liver. (MEDLINEplus)

    New treatment may prevent, reverse liver diseases  Dec 28, 2007
    BEIJING, Dec. 28 (Xinhuanet) -- The best treatment currently available for cirrhosis is a liver transplant, but research into the inner workings of cells may reveal a way to reverse scarring of the liver. Newly released research with mice suggests a drug-based strategy could reprogram cells and make it "feasible to treat it [cirrhosis] and prevent it without a transplant," said study lead author Martina Buck, an assistant professor of medicine at the University of California, San Diego. (Xinhuanet, China)

    New hope for a cure to liver cirrhosis  Dec 28, 2007
    Hopefully this will also help those with other chronic liver diseases which are nothing to do with alcohol, like the auto immune disease Primary bilary cirrhosis. -- It is a shame any illness relating to the liver has the cirrhosis tag on it, which kicks off the nasty remarks we see here. (Times Online)

    Anti-Alcohol Drug Safe in Cases of Liver Cirrhosis  Dec 11, 2007
    Individuals with alcoholic liver disease need to achieve total alcohol abstinence, since medical and surgical treatments for alcoholic liver diseases have limited success when drinking continues, they further note. "Our results suggest that baclofen, because of its anticraving action and safety, could have an important role for treatment of alcohol-dependent patients with advanced liver disease," the investigators conclude. (MEDLINEplus)

    Ligand Presents Positive LGD-4665 Phase I Clinical Trial Results at the American Society of Hematology Annual Meeting (ASH)  Dec 9, 2007
    Based on its strong potency, convenience and potential for dosing flexibility, we believe that LGD-4665 could be used as treatment for a wide variety of diseases associated with thrombocytopenia, including hepatitis C, chemotherapy-induced thrombocytopenia (CIT), myelodysplastic syndromes (MDS), idiopathic thrombocytopenic purpura (ITP) and several other cancers and liver diseases. LGD-4665 Study Design. (BusinessWire)

    Protein protects brain against compound in lead poisoning, liver disease  Dec 7, 2007
    ---Scientists have discovered that a protein known as PEPT2 protects the brains of mice from a naturally occurring but potentially toxic compound present in lead poisoning and in a class of liver diseases that can cause serious neurological complications. Scientists at the University of Michigan found that when dosed with the compound called 5-aminolevulinic acid (5-ALA), mice without the PEPT2 protein died sooner, had neuromuscular dysfunction, and had up to 30 times higher concentrations of... (EurekAlert!)

    New Chimeric Mouse Model For Human Liver Diseases, Drug Testing  Dec 6, 2007
    5, 2007) Cells cultured in the lab are like a fish out of water. Often, their behavior does not reflect their biological function within an entire organ or organism, which, for example, turns studying human liver cells into a big challenge. (Science Daily)

    Safer, cheaper drugs may result from new Salk mouse  Dec 5, 2007
    The same operation may be possible in humans, curing certain inherited liver diseases, said Verma, a professor in the Laboratory of Genetics, in a Salk Institute press release. John McCamant, editor of the Medical Technology Stock Letter in Berkeley, said the new mouse has promise in helping develop drugs. (North County Times)

    Liver transplant offers survival benefits for patients of all sizes  Dec 5, 2007
    Previous studies have shown that morbidly obese patients face higher risk of morbidity and mortality after liver transplantation, leading the American Association for the Study of Liver Diseases (AASLD) to recommend that morbid obesity should be considered a contraindication to the surgery. However, until now, no studies have considered the survival benefit for patients who receive a transplant compared to those who do not. (EurekAlert!)

    Treating patients with psychiatric disorders for hepatitis C  Dec 4, 2007
    Against this epidemiological background, the article by Schaefer and colleagues, Hepatitis C treatment in psychiatric risk patients, represents an important study in the field, write Sanjeev Arora and Cynthia Geppert, in the December issue of Hepatology, a journal published by John Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD). Their editorial is also available online at Wiley Interscience (). (EurekAlert!)

    Powerful Microscope May Help Cancer Research  Nov 28, 2007
    The multiphoton microscope will also support the research of other Centenary scientists particularly in autoimmune and liver diseases. " The multiphoton microscope at the Centenary Institute has two unique features, its imaging mode and laser. The unique imaging mode uses multiple laser beams and means fast moving objects and dynamic processes in living tissue can be viewed, for example, cells in the blood stream. The laser has been enhanced with a unit called an OPO that produces longer... (Science Daily)

    * Working class health can improve  Nov 23, 2007
    As usual, the top three were cancer, accidents and chronic liver diseases and liver cirrhosis. It's the same old stuff because in recent years there have been no big changes on the list, and the top three causes haven't changed. (Taipei Times, Taiwan -- World)

    Scientific Evidence Of The Significant Anti-cancer Effect Of Milk Thistle  Nov 16, 2007
    Being widely used as a folk remedy for liver diseases, milk thistle is safe and well-tolerated, and it protects the liver from drug or alcohol-related injury ... Many of his scientific research publications are focused on viral hepatitis B and C, cirrhosis, and liver cancer, all of which have significantly contributed to our better understanding of common liver diseases. (Science Daily)

    Last shot before flu season  Nov 16, 2007
    Many doctors recommend the flu shot for the following: the elderly, children under 5 years old, pregnant women, patients with chronic lung, heart, and liver diseases, those who are immunosuppressed (with HIV or are receiving drugs to suppress the immune system), those living or working in an environment where influenza can spread fast (such as nursing homes and prisons), and healthcare workers. Who shouldn t get the flu shot. (Pembroke Mariner, MA)

    Vital Therapies Announces Presentation of ELAD(R) 'Artificial Liver' Data at American Association for the Study of Liver Diseases 2007 Annual Meeting  Nov 7, 2007
    BOSTON, Nov. 7 /PRNewswire/ -- Vital Therapies, Inc. (VTI), announced today data from two studies of the company's ELAD(R) (Extracorporeal Liver Assist Device) System were presented at the 2007 American Association for the Study of Liver Diseases (AASLD) Annual Meeting, which was held November 2-6 in Boston, Mass. -- Abstract (#91), "Interim results of Randomized Controlled Trial of ELAD(R) in Acute on Chronic Liver Disease," was presented in a parallel session on Monday, November 5th. (PR Newswire)

    Roche Issues Hepatitis Drug Data  Nov 5, 2007
    Presenting results at the American Association of the Study of Liver Diseases (AASLD) meeting in Boston, the Swiss drugmaker said its investigational hepatitis C drug R1626 showed promising antiviral activity in the phase IIa trial when given with Pegasys (peginterferon alfa-2a) and Copegus. The aforementioned Roche drugs are used together to treat adults with chronic hepatitis C whose liver still works normally and who haven't been previously treated with an interferon alpha. (TheStreet.com)

    Vertex takes hit on data  Nov 3, 2007
    Data from the Annual Meeting of the American Association of the Study of Liver Diseases in Boston showed the drug, telaprevir, in combination with standard treatment eradicated the hepatitis C virus in more than 60 percent of patients who took it as part of a 24-week treatment regime. While that compares favorably with the 50 percent or less cure rate seen in patients who take standard therapies - which are typically taken for a year - some investors had hoped the results would be closer to 70... (Boston Globe)

    Gilead Issues More Viread Data  Nov 3, 2007
    -based company, which gave topline results for both studies in June, is presenting the 48-week results at the American Association for the Study of Liver Diseases annual meeting in Boston (Nov. 2-6). (TheStreet.com)

    Vertex feeling growing pains  Nov 2, 2007
    Vertex plans to present the data in greater detail at a medical conference in Boston next week, the annual meeting of the American Association for the Study of Liver Diseases, which is being held at the Hynes Auditorium through Tuesday. "It's the dawn of a new era" in hepatitis C treatment, said Dr. John Alam, Vertex's chief medical officer. (Boston Globe)

    First Studies Demonstrating Greater than Sixty Percent Sustained Viral Response Rates with Half the Standard Treatment Duration in Genotype 1 Chronic Hepatitis C Patients  Nov 2, 2007
    Data from PROVE 1 and PROVE 2 being presented at the 58th Annual Meeting of the American Association of the Study of Liver Diseases (AASLD) in Boston November 2-6, 2007 represent interim analyses. Vertex is developing telaprevir, an investigational hepatitis C protease inhibitor, in collaboration with Tibotec. (BusinessWire)

    High-fat diet makes mice susceptible to liver injury  Nov 2, 2007
    A high fat diet may kill regulatory T cells in the liver, allowing steatosis (simple fatty liver) to develop into steatohepatitis (fatty liver with inflammation), according to the results of a new study in the November issue of Hepatology, a journal published by John Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (http://www. (EurekAlert!)

    Weight-based Dosing Of Ribavirin Improves Outcomes For Patients With Hepatitis C  Oct 26, 2007
    These findings are in the October issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). See also. (Science Daily)

    U.S. industrial output edges up 0.1%  Oct 17, 2007
    Ocera Therapeutics, a privately held San Diego-based company developing treatments for gastrointestinal and liver diseases, said it has completed patient enrollment in its Phase 3 study of its drug candidate AST-120, a treatment for Crohn's disease patients. 14 buildings are sold in Carlsbad office park. (San Diego Union-Tribune -- Business)

    Health minister outlines strategy for future  Oct 13, 2007
    Other keys to improving China's health include the prevention and control of liver diseases, HIV/AIDS, tuberculosis and schistosomiasis (snail fever), metabolic syndrome and cancer. The strategy also highlights mental health with an accent on the young and the elderly. (Xinhuanet, China)

    Liver transplant surgeon will use his feet, legs (and head) to raise public awareness  Oct 5, 2007
    The money the doctor raises will support educational programs, research, local support groups, and campaigns to raise public awareness of liver diseases, wellness and organ donation. Liver disease affects the health of people of all ages and backgrounds, yet it is not widely understood, he said. (Univeristy of Chicago Chronicle, IL)

    Noninvasive Tests For Cirrhosis May Help To Avoid Liver Biopsy  Oct 5, 2007
    Several trends are likely to produce further increases in death and disease from cirrhosis, including the aging of the population; the epidemic of obesity, which leads to nonalcoholic fatty liver diseases; and the emergence of liver disease among patients with chronic hepatitis C.. Traditionally, liver biopsy has been the "gold standard" technique for diagnosing fibrosis and cirrhosis. (Science Daily)

    Is fasting a nutrition solution?  Oct 3, 2007
    It is not recommended for people with liver diseases to fast. Fasting also can decrease body weight. (Jakarta Post, Indonesia -- Features)

    Combination therapy reverses effects of portal hypertension in rats  Oct 2, 2007
    The study is in the October issue of Hepatology, a journal published by John Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (). (EurekAlert!)

    Transgene Extends Therapeutic Vaccine Candidate TG4040 Development Program Against Chronic Hepatitis C  Oct 1, 2007
    HCV infection leads to liver diseases such as fibrosis, cirrhosis and liver carcinoma which are the prime reason for liver transplants. The current standard of care for patients infected with the HCV genotype 1 (a combination of Pegylated-Interferon Alpha and Ribavirin), effective in 50% of patients completing therapy, is lengthy and often poorly tolerated. (PR Newswire)

    New liver without transplant, from bone marrow stem cells  Sep 29, 2007
    In a series of animal studies, Massachusetts General Hospital researchers successfully treated rats with liver diseases by manipulating their immune response. If this procedure can be repeated in humans, it could potentially reduce the number of donor organs used in urgent transplant procedures, thereby increasing the number available for patients on waiting lists. (Times of India)

    NRG seeks Encina plant upgrade  Sep 20, 2007
    Ocera Therapeutics, a privately held biopharmaceutical company developing therapies to treat gastrointestinal and liver diseases, said it began a Phase 2 study evaluating the efficacy and safety of AST-120 in patients with non-constipating irritable bowel syndrome. The study will be conducted at four centers in Belgium. (San Diego Union-Tribune -- Business)

    Deconstructing 'detox' diets  Sep 15, 2007
    Gregory Gores, M.D., president-elect of the American Association for the Study of Liver Diseases, says to avoid excessive alcohol (no more than a drink a day for women or two for men) and to watch how much acetaminophen you take (generally, no more than 2,000 mg per day -- that's four extra-strength Tylenol pills). Why. (CNN -- Health)

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