Secondhand Smoke Linked To Peripheral Artery Disease In Women Sep 24, 2008
Signs of intermittent claudication. This is the clinical diagnosis given for muscle pain (ache, cramp, numbness or sense of fatigue), classically in the calf muscle, which occurs during exercise and is relieved by a short period of rest. (Science Daily)
Drug Curbs Pain Due to Leg Artery Disease May 13, 2008
NEW YORK (Reuters Health) - People who experience leg pain caused by narrowed arteries in their legs -- a condition called intermittent claudication -- can find some relief by taking the drug naftidrofuryl, a review of published studies indicates. People with intermittent claudication have 37 percent more pain-free walking if they take naftidrofuryl three times a day than those taking inactive placebo, researchers report in The Cochrane Library, a publication of the Cochrane Collaboration, which... (MEDLINEplus)
Personal Health: You name it, and exercise helps it May 2, 2008
Aerobic exercise lowers blood pressure in people with hypertension, and it improves peripheral circulation in people who develop cramping leg pains when they walk a condition called intermittent claudication. The treatment for it, in fact, is to walk a little farther each day. (International Herald Tribune)
Drug Can Reduce Leg Pain Caused By Narrowed Arteries Apr 19, 2008
The symptoms of intermittent claudication are pain, cramp or a sense of fatigue in leg muscles that increases on exercise such as walking, but goes away when the person rests. The condition affects less than 1% of people below the age of 49, but increases to over 5% of those aged 70 and older. (Science Daily)
Taking care of heart may mean healthier brain Jul 28, 2007
Significantly greater declineTo better understand the relationship between various types of heart and blood vessel disease and mental function, the researchers followed 452 elderly individuals for four years, over a third of whom had at least one type of cardiovascular disease such as angina, stroke or intermittent claudication, or reduced blood flow in the legs due to hardening of the arteries. Exercise your mind. (MSNBC -- Health)
Indigo Pharmaceuticals, Inc. Signs License Agreement for INDI-702, a Drug for the Treatment of Arteriosclerosis Obliterans, With Nissan Chemical Industries and Taisho Pharmaceutical Co. Jun 1, 2007
In Japan, Phase 2 studies are being conducted for intermittent claudication caused by arteriosclerosis obliterans, intermittent claudication caused by spinal canal stenosis, and asthma. In the U.S., a Phase 2 study for intermittent claudication caused by arteriosclerosis obliterans has been successfully completed ... Intermittent claudication is a major symptom of arteriosclerosis obliterans. (Primezone Releases)
Intermittent Claudication Mar 22, 2007
Please for full text and personal services. Volume 356:1241-1250. (New England Journal of Medicine)
Ginkgo Biloba in Herbal Medicine Mar 14, 2007
Drug treatment of intermittent claudication. Drugs. (Suite101.com)
ActivBiotics Announces Initiation of Phase II Study in Carotid Atherosclerosis Feb 14, 2007
Additionally, the Company completed enrollment in a Phase III study of rifalazil for the treatment of patients with intermittent claudication, a common manifestation of peripheral arterial disease. PROVIDENCE-1 (Prospective Evaluation of Rifalazil Effect on Vascular Symptoms of Intermittent Claudication and Other Endpoints in Chlamydia Seropositive Patients) is a multinational, double-blind, randomized, placebo-controlled trial evaluating the efficacy and safety of rifalazil in 296 patients with... (Canada Newswire)
BioMarin Initiates Phase 2 Clinical Study of 6R-BH4 in Peripheral Arterial Disease Jan 5, 2007
"Peripheral arterial disease results from endothelial dysfunction and affects approximately eight million Americans, many of whom also suffer from intermittent claudication," stated Emil Kakkis, M.D. Ph ... "This study is the second company-sponsored Phase 2 trial and part of a broader program to evaluate the role of 6R-BH4 in the treatment of different types of cardiovascular diseases. 6R-BH4, commonly known as tetrahydrobiopterin, is an essential enzyme cofactor that is involved in the... (PR Newswire)
