Gene Responsible For Rare Childhood Disease Identified Jul 26, 2008
"By understanding the role of EpCAM in the intestine, it may also lead to better understanding of diseases such as colon cancer and inflammatory bowel disease.". Dr. Sivagnanam's research mentor is Hal M. Hoffman, M.D., an associate professor of medicine and pediatrics at UCSD who also discovered a protein implicated to two other rare disorders: familial cold autoinflammatory syndrome (FCAS), in which affected people develop rashes and other symptoms when exposed to cold air, and Muckle-Wells... (Science Daily)
Researchers identify gene responsible for rare childhood disease Jul 25, 2008
"By understanding the role of EpCAM in the intestine, it may also lead to better understanding of diseases such as colon cancer and inflammatory bowel disease.". . (EurekAlert!)
Guidelines Highlight Key Differences Between Child And Adult Stroke Jul 22, 2008
systemic conditions such as inflammatory bowel disease and autoimmune disorders. head trauma; and. (Science Daily)
Scientists figure out how the immune system and brain communicate to control disease Jul 22, 2008
Headquartered in Manhasset, NY, The Feinstein Institute for Medical Research is home to international scientific leaders in Parkinson's disease, Alzheimer's disease, psychiatric disorders, rheumatoid arthritis, lupus, sepsis, inflammatory bowel disease, diabetes, human genetics, leukemia, lymphoma, neuroimmunology, and medicinal chemistry. The Feinstein Institute, part of the North Shore-LIJ Health System, ranks in the top 6th percentile of all National Institutes of Health grants awarded to... (EurekAlert!)
New Guidelines on Infant Stroke Released Jul 19, 2008
Other risks include head and neck infections, systemic problems such as inflammatory bowel disease and autoimmune disorders; head traumas, and dehydration. Risk factors in the mother that contribute to a stroke in the infant include a history of infertility, premature rupture of the membranes, and preeclampsia. (MEDLINEplus)
Bone Marrow Transplants: Cancer Drug Shows Promise Against Graft Vs. Host Disease Jul 17, 2008
Researchers elsewhere have recently shown that HDAC inhibitors have been beneficial in animal studies of lupus and inflammatory bowel disease. Other studies suggest the drugs could be useful in regulating the immune response in heart and islet cell transplants. (Science Daily)
New Study Sheds Light On How Intracellular Pathogens Trigger The Immune System Jul 17, 2008
"This is important because you don't want the immune system to overreact to non-threats, which is what happens in autoimmune disorders such as inflammatory bowel disease, asthma and multiple sclerosis.". The Listeria bacterium makes headlines when it contaminates deli meats, raw cheeses, cole slaw and other foods. (Science Daily)
Chelsea Therapeutics Reports Progress in Phase II Trial of CH-1504 in Rheumatoid Arthritis Jul 16, 2008
Diseases that may potentially benefit from the compound include RA, psoriasis, inflammatory bowel disease, cancer and other immunological disorders. About Chelsea Therapeutics. (Primezone Releases)
Online Courses Boost Infection Control Skills That Could Prove Vital In A Pandemic Jul 13, 2008
ScienceDaily (July 10, 2008) Online courses are helping staff to develop the skills they need to tackle hospital-acquired infections, such as MRSA and C.difficile, and this expertise could also prove vital in a pandemic, according to a study published in the latest issue of the UK-based Journal of Advanced Nursing. Nursing and healthcare staff who took part in a specially developed online infection control course said that it had improved their infection control procedures and the advice they... (Science Daily)
Cancer Therapies From The Ocean? Jul 8, 2008
The team has focused on finding compounds which interfere with a protein termed NF-kB. This particular protein is known to have a critical role in many types of cancer, as well as a number of other diseases including inflammatory bowel disease, arthritis and asthma, so there is a major drive to find molecules which can inhibit its activity. "We have tested a large number of marine species to see which can prevent NF-kB from working," explains Professor Jaspars. (Science Daily)
32 genes blamed for bowel disorder Jul 1, 2008
Scientists said on Sunday that new research had tripled the number of genetic regions implicated in Crohn's, the most common form of inflammatory bowel disease, and many more were probably still undiscovered. "These explain only about a fifth of the genetic risk, which implies that there may be hundreds of genes implicated in the disease, each increasing susceptibility by a small amount," said Jeffrey Barrett from the Wellcome Trust Centre for Human Genetics at the University of Oxford, who led... (MSNBC -- Health)
Hay Fever & Injections On The NHS Jun 30, 2008
It should only be given with caution to patients with inflammatory bowel disease, stomach ulcers, kidney and heart disease, liver failure and diabetes. Ongoing review of the treatment is important. (Suite101.com)
Complexity of Crohn's disease revealed as 'gene' count tops 30 Jun 30, 2008
New research has trebled the number of genetic regions known to be implicated in Crohn's disease, a form of inflammatory bowel disease, to over thirty. The research, published today in the journal Nature Genetics, has identified a number of potential new targets for drug development as well as providing surprising new links between the condition and other common diseases including asthma. (EurekAlert!)
International team identifies 21 new genetic risk factors for Crohn's disease Jun 30, 2008
"It's amazing that all of the genes indentified in GWAS studies of Crohn's so far align with the pathways that we know are disrupted, systems that sense the presence of microbes and effectively clear them from the body." says Ramnik Xavier, MD, of the Center for the Study of Inflammatory Bowel Disease in the MGH Gastroenterology Unit and the MGH Center for Computational and Integrative Biology, a co-author of the Nature Genetics study. "Mapping the internal circuitry of these systems and... (EurekAlert!)
Hypnosis may ease inflammation in colitis Jun 28, 2008
He noted that it could also be worthwhile to study hypnosis for people with Crohn's disease, another form of inflammatory bowel disease. SOURCE: American Journal of Gastroenterology, June 2008. (Scientific American)
Doctors out of a tight spot Jun 28, 2008
PEDIATRICIANS at a Sydney hospital have developed a world-first non-invasive test for inflammatory bowel disease, which could save hundreds of children having to undergo uncomfortable and time-consuming surgery ... The test would also help the hundreds of children with inflammatory bowel disease who were not always diagnosed quickly, especially when they were young or suffered atypical symptoms ... Last year an Access Economics report found that inflammatory bowel disease costs the community... (Sydney Morning Herald -- Australia)
A sporting chance Jun 23, 2008
When I did, she told me that she remembered that her brother's son, when he was 15, had the same symptoms," recalls Washington. Washington immediately dialed her uncle's number in California and described Mark's behavior. "He said that it sounded like Crohn's disease, which was what his son had had when he was a teenager," say Washington. Crohn's disease -- a chronic, episodic inflammatory bowel disease also known as IBD -- can affect any part of the gastrointestinal tract, from the mouth to the... (NJ.com -- Times)
Worm diet 'treats bowel disorder' Jun 23, 2008
People with inflammatory bowel disease could soon be swallowing worms in an effort to relieve their symptoms ... A number of studies have suggested that live worms could be an effective treatment for conditions like Crohn's disease and colitis, known collectively as inflammatory bowel disease ... As the number of infections by parasites, such as roundworms and human whipworms, has fallen, the number of people being diagnosed with inflammatory bowel disease has increased. (Yahoo News -- Alternative Medicine)
Novel Compound May Treat Acute Diarrhea Jun 22, 2008
Besides diarrheal disease, this potential drug, based on its mechanism of action, could have promising effects in other diseases such as inflammatory bowel disease and some endocrine disorders, Murad said. "The relatively easy chemical synthesis (single step) and a presumed low cost should make it very attractive for therapy of diarrhea in developing countries," Murad wrote in the paper. (Science Daily)
Inexpensive Compound Could Treat Severe Diarrhea Jun 19, 2008
A drug based on this compound may also prove effective in treating inflammatory bowel disease and some endocrine disorders, Murad said. The discovery of this compound is "a promising lead," said Dr. Stanley G. Schultz, a cellular signaling expert at the University of Texas Medical School at Houston who was not involved in the study. (MEDLINEplus)
On Colitis and Colon Cancer Jun 19, 2008
Colon cancer is one of the most serious complications of chronic inflammatory bowel disease. The cumulative risk ranges from 2% among patients who have had colitis for 10 years to 18% among patients who have had colitis for 30 years. (New England Journal of Medicine)
Choice of hospital impacts outcomes for inflammatory bowel disease surgery Jun 19, 2008
Hospitals with higher annual volumes of patients with inflammatory bowel disease (IBD) who undergo surgery have lower in-hospital mortality rates than hospitals with lower volumes of IBD patients, according to a new study by researchers at the Medical College of Wisconsin in Milwaukee. The study also found a trend toward shorter post-operative hospital stays for patients who undergo surgery for Crohn's Disease, a form of IBD, at high-volume centers. (EurekAlert!)
Bowel Disease Flare-Ups Affect Pregnancy Outcomes Jun 18, 2008
NEW YORK (Reuters Health) - For pregnant women with inflammatory bowel disease, a relapse increases the risk that they'll give birth prematurely and have a low-birth-weight infant, according to a new study. Inflammatory bowel disease includes Crohn's disease and ulcerative colitis ... Dr. Deepa Reddy at Mount Sinai Medical Center in New York and colleagues compared 18 pregnant women with inflammatory bowel disease who were hospitalized for a disease relapse and 41 age-matched pregnant women with... (MEDLINEplus)
Long-term safety data on Lialda published in leading GI journal Jun 18, 2008
"This published data demonstrates that Lialda is generally well tolerated and has a strong safety profile," said Gary R. Lichtenstein, MD, co-author of study 303 and director of the Center for Inflammatory Bowel Diseases at the Hospital of the University of Pennsylvania ... Mesalamine has been associated with an acute intolerance syndrome (three percent of patients in clinical trials with mesalamine or sulfasalazine) that may be difficult to distinguish from a flare of inflammatory bowel... (EurekAlert!)
New compound may treat serious bacterial diarrhea Jun 17, 2008
And it may help with inflammatory bowel disease, but that needs to be tested, he said. Murad has applied for a patent on the compound and now hopes to secure funding to start human trials. (Scientific American)
Raw milk - the new craze Jun 17, 2008
Marta used to be lactose intolerant and also suffered from colitis, an inflammatory bowel disease, for eight years. But she has felt no ill effects from the raw milk. (iAfrica.com)
Team reports Jun 12, 2008
" Last week: Harvick motored home with a 13th-place finish. Etc.: On Tuesday, the RCR NASCAR Sprint Cup Series over-the-wall crews made a special visit to the Victory Junction Gang Camp in Randleman, N.C. While at the camp, the crews ate dinner with the campers and demonstrated real-time pit stops. Additionally, RCR's over-the-wall teams took hot air balloon rides, played carnival games and made snow cones with the campers. All the campers this week suffer from Crohn's disease, a chronic... (USA Today -- Sports)
Common Bowel Problem Linked To Chili Pepper Pain Receptor Jun 12, 2008
24, 2007) People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to recent. (Jan. (Science Daily)
3 sequencing companies join 1000 Genomes Project Jun 12, 2008
The HapMap catalog laid the foundation for the recent explosion of genome-wide association studies that have identified more than 130 genetic variants linked to a wide range of common diseases, including type 2 diabetes, coronary artery disease, prostate and breast cancers, rheumatoid arthritis, inflammatory bowel disease and a number of mental illnesses. The HapMap catalog, however, only identifies genetic variants that are present at a frequency of 5 percent or greater. (EurekAlert! -- Business News)
Discovery Of New Family Of Genetic Mutations Involved In Inflammatory Intestinal Disease Jun 6, 2008
Dr. Festen's team analysed the genetic variants in the immune pathway in a three-step design in a group of 1851 patients with inflammatory bowel disease (IBD) and 1936 controls. The two most common manifestations of this condition are Crohn's disease and ulcerative colitis. (Science Daily)
Humans Have Ten Times More Bacteria Than Human Cells: How Do Microbial Communities Affect Human Health? Jun 6, 2008
Daniel Frank of the University of Colorado, Boulder, is part of a team that is exploring the role bacterial communities in the human digestive tract may play in inflammatory bowel diseases. They are collecting and comparing microbial communities in samples from people with Crohn's disease, people with ulcerative colitis and healthy volunteers. (Science Daily)
New Approach To Treating Autoimmune Disease Developed Jun 4, 2008
In healthy people, a small but crucial group of immune cells called regulatory T cells, or T-regs, keeps autoimmunity in check, but in people with inflammatory bowel disease (IBD), one of the most common autoimmune disorders, too few of these cells appear in the diseased intestine, and the ones that do fail to function properly. The new Weizmann Institute approach consists of delivering highly selective, genetically engineered functioning T-regs to the intestine. (Science Daily)
Recent developments at Burnham Institute Jun 3, 2008
Autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease might be treated by blocking the traffic of immune cells throughout the body. Dr. Minoru Fukuda and collaborators showed that certain sugar molecules displayed on blood vessels attract immune cells called lymphocytes, allowing them to migrate out of the blood stream. (EurekAlert!)
Incidence of pre-cancerous masses in the colon same in patients in ... Jun 1, 2008
Individuals who could be deemed "high-risk" because of a family history of colon cancer, a personal history of inflammatory bowel disease or any malignancy other than skin cancer were excluded from the sample. They found that in 40 to 49 age group, 79 patients, or 14 percent, had one or more adenoma. (TopNews)
Gut feeling: bacteria may inspire bowel treatment May 30, 2008
WASHINGTON (Reuters) - A substance produced by one of the many types of bacteria that inhabit the human gut may inspire a new kind of drug for inflammatory bowel disease, scientists said on Wednesday. The researchers found that a complex sugar molecule made naturally by a species of intestinal bacteria called Bacteroides fragilis prevented the development of an animal version of inflammatory bowel disease in laboratory mice ... They expressed hope this sugar molecule could be developed as a... (Reuters India)
Antibiotics Accompanying Surgery Prevent Some Infections But Increasingly Cause Another May 29, 2008
29, 2007) Clostridium difficile infection is four times more likely to kill patients with inflammatory bowel disease. C difficile is an important cause of diarrhea among inpatients, and the numbers of new. (Science Daily)
Getting better with a little help from our 'micro' friends May 29, 2008
-- A naturally occurring molecule made by symbiotic gut bacteria may offer a new type of treatment for inflammatory bowel disease, according to scientists at the California Institute of Technology ... In particular, Mazmanian and his colleagues found that PSA induced particular immune-system cells called CD4+ T cells to produce interleukin-10 (IL-10), a molecule that has previously been shown to suppress inflammation--and offer protection from inflammatory bowel disease ... "The most immediate... (EurekAlert!)
Research Team Clones Genes Responsible for Amino Acid Absorption May 24, 2008
May 23 /PRNewswire-USNewswire/ -- Researchers at the West Virginia University School of Medicine have discovered ways to block substances that interfere with absorption of nutrients in patients with inflammatory bowel disease (IBD), according to Uma Sundaram, M.D., Section Chief of Digestive Diseases at WVU. "The most important step before development of drugs that could replace steroids in treating this chronic condition is to find out the specific bodily immune substance that causes the... (PR Newswire)
Clinical Trials Update: May 23, 2008 May 24, 2008
Inflammatory Bowel Disease. Urinary Incontinence. (Health-Finder)
Gene Therapy: Oral Gene Delivery System For Inflammatory Bowel Disease Works, Study Shows May 23, 2008
ScienceDaily (May 22, 2008) Inflammatory bowel disease (IBD) afflicts as many as 10 out of 100,000 people in the United States and currently available treatment options are short-term and invasive with toxic side effects ... Oral IL-10 Gene Delivery in a Microsphere-based Formulation for Local Transfection and Therapeutic Efficacy in Inflammatory Bowel Disease ... 16, 1999) Researchers at the University of Pennsylvania Medical Center have shown that a class of anti-diabetic agents currently on... (Science Daily)
Surgical Outcomes Depend on a Host of Variables May 23, 2008
A second study found that hospitals with a high annual volume of patients with inflammatory bowel disease (IBD) had lower death rates among IBD patients who had surgery and had shorter post-surgery stays for patients with Crohn's disease. Despite caring for patients with more severe disease, these high-volume hospitals didn't have longer patient stays or higher costs, said the Medical College of Wisconsin researchers who analyzed data on more than 140,000 patient discharges. (MEDLINEplus)
Abbott's Humira tames Crohn's in 29% of cases May 22, 2008
One of those earlier studies, called Charm, involved 854 patients with moderate to severe Crohn's disease, including ones who had never been treated and patients who had received earlier treatment for the often dangerous inflammatory bowel disease ... "Remicade's data only goes out to one year in published literature," Kent said in an interview, referring to Johnson on's older blockbuster treatment for the inflammatory bowel disease believed to affect more than 500,000 Americans. (Crain's Chicago Business)
Ardea Biosciences Presents Preclinical Data on RDEA119 Demonstrating Favorable Anti-Inflammatory Profile for Potential Use in Ulcerative Colitis May 21, 2008
The MEK1/2 pathway is important in cell cycle regulation in inflammatory bowel disease, including ulcerative colitis and Crohn's disease ... "Despite the existing treatments, there are still significant unmet medical needs for inflammatory bowel disease. Blocking the MEK1/2 pathway appears to be a promising strategy in the ongoing search for a new generation of therapies aimed to treat ulcerative colitis and Crohn's disease," said Barry D. Quart, PharmD, Ardea Biosciences' President and CEO.... (PR Newswire)
Tuberculosis not the only risk from new immunological drugs May 21, 2008
A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of serious infections other than the known risk of tuberculosis. The survey published is in the June 1 issue of Clinical Infectious Diseases, currently available online. (EurekAlert!)
Pain Free Without Numbness: Substance Combination With Chili Peppers May 20, 2008
(May 1, 2003) Researchers at Duke University Medical Center have found that a specific nerve cell receptor appears to be necessary to initiate the development of inflammatory bowel disease (IBD), findings they. . (Science Daily)
Fight corectal cancer, here's what you need to know May 20, 2008
Certain rare but high-risk genetic syndromes, including familial adenomatous polyposis and Lynch syndrome, caused by gene mutations that can now be detected with DNA testing, account for about 10 percent of the total cases, and as many as 30 percent are linked to family histories of colorectal cancer or inflammatory bowel diseases, says Dr. Keith Argenbright, medical director UT Southwestern Moncrief Cancer Resources ... People with a family history of colon cancer or inflammatory bowel disease,... (Atlanta Journal-Constitution -- Health)
New Technology Speeds Gastrointestinal Disease Diagnosis May 20, 2008
SUNDAY, May 18 (HealthDay News) -- A real-time microscopic technique called confocal laser endomicroscopy (CLE) could lead to earlier diagnosis and treatment of gastrointestinal disorders such as cancer, reflux disease, and inflammatory bowel disease. That's the conclusion of several studies to be presented May 18 at the Digestive Disease Week conference in San Diego. (MEDLINEplus)
Professors Marc Feldmann and Sir Ravinder Maini Named Winners of the 2008 Dr. Paul Janssen Award for Biomedical Research May 13, 2008
Feldmann said, "We are very pleased with the widespread clinical applicability of our discovery that a messenger molecule, TNF, was an effective target for treatment not only in rheumatoid arthritis but also other chronic inflammatory conditions, such as inflammatory bowel disease, ankylosing spondylitis and psoriasis. This discovery suggested that other cytokine messenger molecules are also good treatment targets and has led to an emerging branch of medicine -- anti-cytokine therapy. I believe... (PR Newswire)
One Third of Hospital Toilets Not Properly Cleaned: C. Difficile Germs Linger May 13, 2008
ScienceDaily (May 12, 2008) A team of Canadian scientists using a lotion which glows under ultraviolet light have shown that up to a third of patient toilets are not properly cleaned. Their findings also show that spores from the nasty bacteria Clostridium difficile (C. difficile) linger in the loo even when it has been thoroughly wiped down. (Science Daily)
MMR research timeline May 11, 2008
The researchers concluded that after a decade's effort to detect all severe adverse effects associated with the MMR vaccine they could find "no data supporting the hypothesis that it would cause pervasive developmental disorder or inflammatory bowel disease.". April 2000. (BBC News -- Health)
Eurand Reports First Quarter 2008 Key Achievements and Financial Results May 9, 2008
Highlights: * EUR-1008 (Zentase(r)) NDA accepted and granted priority review status by FDA * EUR-1008 (Zentase(r)) MAA received eligibility for centralized review procedure in European Union * In-licensed corticosteroid product for inflammatory bowel disease (IBD) in the U.S. and Canada from Chiesi Farmaceutici SpA * OTC Unisom(r) SleepMelts(tm), developed by Eurand, launched in U.S. by Chattem, Inc. * Amrix(r) patent application received notice of allowance from USPTO * EUR-1025, once-daily... (Primezone Releases)
Richard Bordeleau to join Advitech's Board of Directors May 8, 2008
Effective and safe, these products play a role in the prevention of immune-mediated inflammatory disorders, such as psoriasis and inflammatory bowel disease. Advitech produces Dermylex(R) for the treatment of mild-to-moderate psoriasis. (Canada Newswire)
Immune system pathway identified to fight allergens, asthma May 8, 2008
Therapy directed against c-Kit specifically on dendritic cells using compounds coupled to c-Kit inhibitors such as Gleevec, a drug that is already FDA-approved and used in cancer treatment, may alleviate allergic diseases and, potentially, inflammatory bowel disease. . (EurekAlert!)
Nuvelo Receives Nasdaq Notification May 3, 2008
Nuvelo's development pipeline includes NU172, a direct thrombin inhibitor in Phase 1 development for use as a potential short-acting anticoagulant during medical or surgical procedures; and preclinical candidate NU206, a Wnt pathway modulator for the potential treatment of chemotherapy/radiation therapy-induced mucositis and inflammatory bowel disease. In addition, Nuvelo is pursuing research programs in leukemia and lymphoma therapeutic antibodies and Wnt signaling pathway therapeutics to... (PR Newswire)
Left because of understaffing, pathologist says May 2, 2008
Anti-depressants could help people suffering from Inflammatory Bowel Disease, as new research points to a link between the condition and depression. A t least 79,000 elementary and high school students in Ontario say they've tried the choking game, a dangerous activity in which a person self-asphyxiates or has someone else choke them, a new survey of adolescent behaviour has found. (CBC.ca)
Inflammatory Bowel Diseases Share Some Genetic Risk Factors May 2, 2008
MONDAY, April 28 (HealthDay News) -- The inflammatory bowel diseases ulcerative colitis and Crohn's disease appear to share several genetic variants and risk factors, two new British studies suggest ... Ulcerative colitis is a common inflammatory bowel disease, while Crohn's disease is a related, but chronic disorder of the intestine. (MEDLINEplus)
New drug approved to treat Crohn's disease Apr 23, 2008
Crohn's disease is a chronic, inflammatory bowel disease that affects more than 1 million men and women worldwide. It has no cure and its cause is unknown. (Xinhuanet, China)
Bedford biotech gains steam and attention Apr 22, 2008
Resolvyx eventually hopes to determine whether the drugs can effectively treat more conditions, including rheumatoid arthritis, inflammatory bowel disease, cardiovascular diseases, and other eye problems. Rubin said the latest venture capital round will give the company enough money to last through the third quarter of 2009, when it hopes to have enough positive data from clinical trials to significantly increase the value of Resolvyx - enabling it to raise more venture capital or form a... (Boston Globe)
Growth Hormone Is Used To Treat Twice As Many Short Boys Than Girls In The US And Asia Apr 21, 2008
A variety of diseases may cause growth failure -- among them, hormone deficiencies, Turner syndrome (a chromosome abnormality found only in females) and gastrointestinal conditions such as celiac disease or inflammatory bowel disease. For some, growth failure is the only symptom. (Science Daily)
A Silent Killer ... A Silent Killer ... New Website to help pass on info ... Community Choir to perform ‘Requiem’ ... Local farmers markets in planning process ... A name to remember ... ';var marqueewidth="350px";var marqueeheight="25px";var marqueebgcolor="#FFFFFF";////NO NEED TO EDIT BELOW THIS LINE////////////var pauseit=1;var marqueespeed=1 //slow speed down by 1 for NSvar copyspeed=marqueespeedvar pausespeed=(pauseit==0)? copyspeed: 0var iedom=document.all||document.getElementByIdif (iedom)document.write(''+marqueecontent+'')var actualwidth=''var cross_marquee, ns_marqueefunction populate(){if (iedom){cross_marquee=document.getElementById? document.getElementById("iemarquee") : document.all.iemarqueecross_marquee.style.left=parseInt(marqueewidth)+8+"px"cross_marquee.innerHTML=marqueecontentactualwidth=document.all? temp.offsetWidth : document.getElementById("temp").offsetWidth}else if (document.layers){ns_marquee=document.ns_marquee.document.ns_marquee2ns_marquee.left=parseInt(marqueewidth)+8ns_marquee.document.write(marqueecontent)ns_marquee.document.close()actualwidth=ns_marquee.document.width}lefttime=setInterval("scrollmarquee()",20)}window.onload=populate;function scrollmarquee(){if (iedom){if (parseInt(cross_marquee.style.left)>(actualwidth*(-1)+8))cross_marquee.style.left=parseInt(cross_marquee.style.left)-copyspeed+"px"elsecross_marquee.style.left=parseInt(marqueewidth)+8+"px"}else if (document.layers){if (ns_marquee.left>(actualwidth*(-1)+8))ns_marquee.left-=copyspeedelsens_marquee.left=parseInt(marqueewidth)+8}}if (iedom||document.layers){with (document){document.write('')if (iedom){write('')write('')write('')write('')}else if (document.layers){write('')write('')write('')}document.write('')}}Friday, April 18, 2008 Emla Caroline Holsted shows the socks she decorated to help promote awareness of Deep Vein Thrombosis (DVT). Children can decorate socks this Saturday at the Grand Prairie Health & Wellness Expo. (Submitted photo) A Silent Killer Apr 19, 2008
Risk factors contributing to DVT include congestive heart of respiratory failure, restricted mobility, cancer, infection, obesity, surgery, varicose veins, prior history of DVT, chronic lung disease, inflammatory bowel disease and smoking. Those age 40 and older are also at increased risk. (Stuttgart Daily Leader, AR)
Mortgage rates unchanged or dipping slightly Apr 18, 2008
Carlsbad-based Regulus Therapeutics said it will receive $20 million from GlaxoSmithKline after signing a collaboration agreement on the development of new microRNA-targeted therapeutics to treat inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. Regulus is a joint venture between Carlsbad-based Isis Pharmaceuticals and Alnylam Pharmaceuticals to focus on microRNAs, a recently discovered class of genetically encoded proteins believed to regulate a large number of... (San Diego Union-Tribune -- Business)
Vitamin D And Calcium Influence Cell Death In The Colon, Researchers Find Apr 15, 2008
29, 2008) Individuals with the inflammatory bowel disease ulcerative colitis are at increased risk of developing colon cancer. New data have identified a central role for the soluble factor TNF-alpha in the. (Science Daily)
Eurand in Licenses Corticosteroid GI Product From Chiesi Farmaceutici SpA Apr 15, 2008
The product, marketed in Europe as Clipper(tm) 5 mg tablets, is an enteric coated, controlled release formulation of beclomethasone dipropionate, a corticosteroid which is marketed in Europe for use in the treatment of Ulcerative Colitis, the most prevalent type of inflammatory bowel disease (IBD) ... Ulcerative colitis is a type of inflammatory bowel disease that produces inflammation and ulcers along the inside of the large intestine ... (1) Lichtenstein GR, Abreu MT, Cohen R, Tremaine W.... (Primezone Releases)
U.S. Biotechs On Sale Apr 12, 2008
Millennium says its experimental drugs for inflammatory bowel disease and Crohn's disease hold promise. Takeda is making a big push to get into the U.S. A decade ago, Takeda did no business in North America; in the fiscal year that ended in March 2007, the region accounted for 33% of its sales. (Forbes -- Business)
Takeda Takes Out Millennium Apr 11, 2008
Millennium also has a healthy pipeline of oncology and anti-inflammatory candidates, including a therapy for inflammatory bowel disease that's on track to enter Phase 3 clinical trials later this year or by early 2009. "Millennium greatly strengthens Takeda's global oncology portfolio," said Takeda President Yasuchika Hasegawa. (Forbes -- Markets)
