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    News, Reviews, and Articles on Head and Neck Cancer

    Archives: Head and Neck Cancer

    Introgen sell-off continues  Sep 5, 2008
    On Tuesday Austin-based Introgen announced the FDA had declined to accept its application to market Advexin, the head and neck cancer drug the company has spent more than a decade developing. That news prompted Introgen s (Nasdaq: INGN) stock to drop more than 35 percent on Tuesday to 57 cents a share. (Austin Business Journal, TX)

    FDA refuses Introgen application; stock in freefall  Sep 3, 2008
    Introgen (Nasdaq: INGN) says the FDA has notified the company that its application for its Advexin head and neck cancer treatment was not complete and would therefore not be filed at this time ... We believe in the potential of Advexin as a treatment option for head and neck cancer, an area of significant unmet need for today s cancer patient, says Introgen CEO David Nance ... We are encouraged by our clinical data and believe that the 40,000 Americans who are diagnosed with head and neck cancer... (Austin Business Journal, TX)

    ImClone: BMS offer for company seen reaching USD 67-70  Aug 29, 2008
    Alternatively, the person familiar said he believes that more mileage could be derived from Erbitux, which, in combination with radiation therapy, is indicated for the treatment of a certain type of locally or regionally advanced head and neck cancer. He said that going forward the drug in colorectal cancer has proven to double survival rates in third line and has proven results in non-small cell lung cancer, which he noted has a larger indication. (FT.com -- Markets)

    Cancer slows UConn coach Calhoun but doesn't stop him  Aug 26, 2008
    " The most recent battle began as soon as Calhoun realized he was dealing with something worse than an upper respiratory infection brought on by the end of another season. After telling his doctors the growth had increased in size, a biopsy was performed April 24. Jeffrey Spiro, co-director of the Multidisciplinary Head and Neck Cancer Team at the UConn Health Center, operated without Calhoun's condition becoming public knowledge, but it was obvious radiation treatments would change that. Spiro... (USA Today -- Sports)

    Cel-Sci lets Teva sell cancer drug  Aug 20, 2008
    The licensing agreement is initially restricted to the areas of head and neck cancer. Teva has the rights, subject to certain conditions, to extend the licensing agreement to include other cancers during the term of this agreement. (Washington Business Journal, DC)

    Adherex Reports Second Quarter 2008 Financial Results  Aug 13, 2008
    - In May, we completed a license agreement with the Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital (NCI-AVL) for the exclusive use of data from a completed Phase III trial using sodium thiosulfate (STS) to prevent platinum-induced hearing loss in adults with head and neck cancer ... We also have plans to initiate a further Phase III trial with STS in adult head and neck cancer patients in the U.S. later this year. (CCNMatthews Press Releases)

    ImClone Calls Bristol Offer Too Low  Aug 5, 2008
    Erbitux is approved for colorectal and head and neck cancer in the United States, and Canada, while a recent approval for the drug in Japan and new lung cancer data are expected to drive sales. ImClone said it believed the pipeline business "may be extremely valuable and significantly increase stockholder value as a separate business.". (ABC News -- Wire)

    Bristol offers to buy ImClone for $60 a share  Aug 1, 2008
    Bristol co-promotes Erbitux, which is approved for colorectal and head and neck cancer, in the United States, and Canada, while a recent approval for the drug in Japan and new lung cancer data are expected to drive sales. Germany's Merck KGaA () has rights to Erbitux in other countries. (Yahoo News -- Pharmaceutical Industry News)

    Bristol-Myers offers $4.5 billion for ImClone  Aug 1, 2008
    New York-based Bristol-Myers already owns about 17 percent of ImClone and is a longtime U.S. partner on the colon and head and neck cancer drug Erbitux. In my view, and in the view of our board of directors, this transaction makes compelling business sense for both of our companies and is in the best interests of our respective shareholders and the cancer patients for whom our companies life saving medicines are so important, Bristol-Myers Chairman and Chief Executive James M. Cornelius... (MSNBC -- Business)

    US stocks slide on GDP, jobless data  Aug 1, 2008
    Web search enhanced by. Friday August 1, 2008 MYT 12:17:42 PM. (The Star Online, Malaysia -- Business)

    Wall Street slides on GDP, jobless data  Aug 1, 2008
    Bristol-Myers, which already owns about 17 percent of ImClone, is a U.S. partner for the colon and head and neck cancer drug Erbitux. ImClone surged $17. (San Diego Union-Tribune)

    U.S. regulator to tighten use of Amgen anemia drugs  Jul 31, 2008
    But the new labels will not advise against use of the drugs for all patients with breast cancer or head and neck cancer, something that had been recommended by an advisory panel to the FDA in March. One impact of the label changes could be to make it less likely that Medicare will loosen reimbursement policies for the drugs. (International Herald Tribune -- Money Report)

    Oncolytics Biotech Inc. Announces 2008 Second Quarter Results  Jul 30, 2008
    "Oncolytics experienced a strong second quarter with the reporting of durable clinical responses to REOLYSIN(R) combination therapy treatment in refractory head and neck cancer patients," said Dr. Brad Thompson, President and CEO of Oncolytics ... MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS This discussion and analysis should be read in conjunction with the unaudited interim consolidated financial statements of Oncolytics Biotech Inc. as at and for the... (PR Newswire)

    Dr. Pou's trial changes laws and her life  Jul 30, 2008
    Today, she is busy as a head and neck cancer specialist and surgeon. She is on the faculty of LSU Health Sciences Center in New Orleans and treats her patients and the needy of the state, commuting to clinics set up in Baton Rouge. (WWLTV.com, LA)

    Teamwork Cuts Out Unnecessary Biopsies, Researchers Find  Jul 26, 2008
    ScienceDaily (July 25, 2008) Unnecessary biopsies could be a thing of the past for patients undergoing treatment for head and neck cancer ... Often used prior to and after cancer treatment, the highly sensitive PET-CT has improved the ability to detect and treat head and neck cancer ... Unnecessary biopsies are dangerous for head and neck cancer patients who have already undergone intensive radiation and chemotherapy. (Science Daily)

    Head And Neck Cancer: Quick Way To Determine If Cancer Has Spread  Jul 25, 2008
    ScienceDaily (July 24, 2008) For patients with head and neck cancer, accurately determining how advanced the cancer is and detecting secondary cancers usually means undergoing numerous tests - until now. New Saint Louis University research has found that the PET-CT scanner can be used as a stand-alone tool to detect secondary cancers, which occur in 5 to 10 percent of head and neck cancer patients ... The study findings, which were presented on July 22, at the 7th International Conference on... (Science Daily)

    US surgeons to honour RPA doctor  Jul 20, 2008
    The popular professor is in San Francisco, with his wife Gail, at the 7th International Conference on Head and Neck Cancer. A keynote lecture named in his honour will be delivered tomorrow. (Sydney Morning Herald -- Australia)

    Gene Variations In Diverse Patient Populations Determine Who Responds Best To An Antidepressant  Jul 17, 2008
    (May 19, 2008) Taking the antidepressant citalopram before beginning treatment for head and neck cancer may help prevent depression during therapy, according to results of a pilot. (Mar. (Science Daily)

    Adam Feuerstein  Jul 15, 2008
    But in his article Feuerstein says that "doesn't explain why survival for Advexin-treated patients overall was so low." He goes on to say: "Introgen says that 75 percent of head and neck cancer patients are 'Advexin favorable' so surely, that should translate into a survival benefit no matter how the patients are analyzed.". On June 30 Austin-based Introgen -- which has most of its staff and operations in Houston and only its executive team in Austin -- announced it had applied with the U.S.... (Austin Business Journal, TX)

    Amgen to Pay J&J $200 Million to Settle Antitrust Suit  Jul 13, 2008
    A panel of experts recommended in March that the U.S. Food and Drug Administration change the drugs' labels to say that they should not be given to patients with potentially curable cancers who are undergoing treatment, or to patients with advanced breast cancer or head and neck cancer. A decision by the FDA is expected any day. (ABC News -- Wire)

    Introgen cuts 29% of jobs as it moves to market cancer therapy  Jul 8, 2008
    Advexin p53 is designed to treat recurrent head and neck cancer. By harnessing the body's natural tumor-suppression mechanisms, the treatment fights cancer without some of the toxicities associated with conventional cancer treatments. (Austin Business Journal, TX)

    Introgen stock rises as company seeks FDA approval of cancer drug  Jul 1, 2008
    Advexin p53 is designed to treat recurrent head and neck cancer ... "With the use of p53 biomarkers, Advexin will provide more effective and less toxic treatment for head and neck cancer patients who have limited treatment options.". (Austin Business Journal, TX)

    GlaxoSmithKline, Exelixis to end 6-year collaboration  Jun 28, 2008
    The compound, now called GSK089, is in Phase II trials for papillary renal cell carcinoma, gastric cancer and head and neck cancer. GSK can pick an additional compound among six programs: XL184, which will start Phase III trials this summer for glioblastoma, medullary thyroid cancer and non-small cell lung cancer; XL820, in Phase II for gastrointestinal stromal tumor; XL281, in Phase I for patients with advanced solid tumors; XL228, in Phase I for chronic myelogenous leukemia, Philadelphia... (San Francisco Business Journal)

    Caphosol favorably impacts both the rate and severity of oral mucositis in cancer patients  Jun 28, 2008
    The most common malignancies among the participants were breast cancer (31 percent), head and neck cancer (31 percent) and colorectal cancer (11 percent) ... The use of Caphosol also had a favorable impact on the severity of OM: Mild OM (Grade 0/1) was found in more than 90 percent of chemotherapy patients and 40 percent of head and neck cancer patients ... Severe OM (Grade 3/4) was found in only 1-2 percent of chemotherapy patients and 18 percent of head and neck cancer patients (with only one... (EurekAlert!)

    Cancer center celebrates an anniversary  Jun 25, 2008
    "We have a whole generation of head and neck cancer patients who will never get surgery now because we have proved that combination therapy can be just as effective without the need for surgery," Foens said. "If those patients had to coordinate their treatments in Waterloo and Grundy Center or Mason City it would be very difficult for them to continue on with their daily activities. ... This kind of practice was revolutionary 20 years ago, but it is still meeting our patients' needs today.". (Waterloo-Cedar Falls Courier)

    YM BIOSCIENCES ANNOUNCES FDA LIFTS CLINICAL HOLD ON AEROLEF(R) AND CLEARANCE OF A PHASE II CLINICAL TRIAL  Jun 20, 2008
    It is approved in several countries for treatment of various types of head and neck cancer. This press release may contain forward-looking statements, which reflect the Company's current expectation regarding future events. (PR Newswire)

    An HIV-Positive Man with Cutaneous Merkel-Cell Carcinoma  Jun 19, 2008
    Dr. Gregory K. Robbins (Infectious Diseases): A 63-year-old man was referred to the clinic for head and neck cancer, a multidisciplinary unit of this hospital, for management of cutaneous Merkel-cell carcinoma. He had been well until 3 months earlier, when he noted a small, painless nodule on the superior, right-central aspect of his forehead. (New England Journal of Medicine)

    Combining Radiation And Surgery Significantly Improves Survival For Head And Neck Cancer Patients  Jun 15, 2008
    14, 2008) Adding radiation therapy to surgery significantly improves overall survival in patients diagnosed with node-positive head and neck cancer when compared to treating with surgery alone, according to a study in the June issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology ... Radiation therapy is commonly used after surgery to treat some head and neck cancers, but very few studies have... (Science Daily)

    Police chief battles cancer, speaks out against chew tobacco  Jun 5, 2008
    "I was still trying to recover from being cut head to toe when they sent me to chemo and radiation," said Hahn, 33, who was diagnosed with head and neck cancer in April 2007 ... Four days later Hahn was diagnosed with head and neck cancer and scheduled for emergency surgery at the Huntsman Cancer Institute at the University of Utah in Salt Lake City. (Casper Star-Tribune, WY)

    Drugs show success in the treatment of several cancers  Jun 3, 2008
    Patients with locally advanced head and neck cancer may respond better to treatment when the drug cetuximab is added to standard chemotherapy, according to findings presented by University of Pittsburgh researchers yesterday in Chicago at the annual meeting of the American Society of Clinical Oncology. Out of 37 patients, 32 responded to initial therapy with that treatment regimen, and all patients had full or partial reduction of their tumors later after radiation treatment, said Dr. Ethan... (Pittsburgh Post Gazette)

    Anemia Drugs May Speed Tumor Growth in Some Cancer Patients  Jun 3, 2008
    They also voted to recommend against the drugs' use in patients with breast or head and neck cancer ... The results of the current study were based on analyses of tumor samples from 101 patients diagnosed with head and neck cancer who had participated in a previous phase III trial of erythropoietin. (MEDLINEplus)

    Acupuncture Eases Side Effects of Head, Neck Cancer Treatments  Jun 3, 2008
    SUNDAY, June 1 (HealthDay News) -- Two of the more common and unpleasant side effects of treatment for head and neck cancer patients may be relieved by the ancient Chinese practice of acupuncture ... Neck dissection, or removal of the lymph nodes and surrounding tissue, is common in treating head and neck cancers. (MEDLINEplus)

    Study is seen as boost for ImClone  Jun 2, 2008
    It is also approved to treat head and neck cancer. But data presented here could change that. (Boston Globe)

    UPDATE:Colon Cancer Study Backs Gene's Role In Erbitux Benefit  Jun 2, 2008
    It is already approved to treat head and neck cancer, as well as colorectal cancer that has failed previous therapy. The response rate in the Erbitux arm was 59% in wild-type patients, compared to 43% in chemotherapy alone. (CNNMoney.com)

    Easing The Pain After Cancer Surgery  Jun 2, 2008
    Acupuncture eases pain in head and neck cancer surgery Posted: 02 June 2008 1510 hrs. Photos. (Channelnewsasia.com)

    Cancer drug developed by Introgen founder meets with clinical success  Jun 1, 2008
    Advexin, a modified adenovirus that uses the tumor-suppressing gene p53, is being used for end-stage head and neck cancer. Introgen co-founder and M.D. Anderson Professor Jack Roth invented the drug. (Austin Business Journal, TX)

    Acupuncture reduces pain and dysfunction in head and neck cancer patients after neck dissection  Jun 1, 2008
    New data from a randomized, controlled trial found that acupuncture provided significant reductions in pain, dysfunction, and dry mouth in head and neck cancer patients after neck dissection ... Neck dissection is a common procedure for treatment of head and neck cancer. (EurekAlert!)

    Gene Therapy Increases Survival For End-stage Head And Neck Cancer  May 30, 2008
    Introgen Therapeutics, Inc., reported results of its phase III trial of Advexin(r), a modified adenovirus that expresses the tumor-suppressing gene p53, for end-stage head and neck cancer ... The trial showed that p53 expression in the patient's tumor before treatment is a reliable biomarker for how to treat head and neck cancer ... Introgen developed a commercial-grade version of the drug and advanced it through phase II and III clinical trials for head and neck cancer. (Science Daily)

    Quality of life predicts cancer survival, U-M study finds  May 30, 2008
    Head and neck cancer patients who reported lower physical quality of life were more likely to die from their disease, according to a new study from the University of Michigan Comprehensive Cancer Center ... The researchers surveyed 495 people at four hospitals who had been diagnosed with head and neck cancer within the previous two years ... Based on their findings, the study authors recommend routine quality of life assessments of patients with head and neck cancer, before treatment and again... (EurekAlert!)

    New Immunization Strategy Could Be Effective Against 10 To 15 Percent Of All Cancers  May 28, 2008
    20, 2007) Researchers have developed a vaccine strategy for head and neck cancer that targets multiple peptides to activate the immune system to attack tumors. Their findings on cancer vaccines will be. (Science Daily)

    Fruit, Veggies May Lower Head and Neck Cancer Risk  May 27, 2008
    Smoking and heavy drinking are two major risk factors for head and neck cancers, but even when the researchers accounted for such lifestyle factors, fruits and vegetables remained linked to lower cancer risks ... Past studies have suggested that fruits and vegetables and the nutrients they contain -- including various antioxidant compounds -- might help protect against head and neck cancers ... For example, participants who ate the most vegetables -- typically between three and four servings a... (MEDLINEplus)

    Antidepressant May Help Head/Neck Cancer Patients  May 27, 2008
    NEW YORK (Reuters Health) - The results of a pilot study suggest that antidepressant therapy with Celexa during treatment for head and neck cancer reduces the risk of depression and diminishes the impact of cancer treatment on quality of life. Depression has been reported in up to 40 percent of patients with head and neck cancer "typically within the first 3 months of diagnosis," Dr. William M. Lydiatt and colleagues write in the journal, Archives of Otolaryngology -- Head and Neck Surgery ...... (MEDLINEplus)

    U of L researchers link HPV with head, neck cancers  May 21, 2008
    Cancer researchers at the 's James Graham Brown Cancer Center have found that the human papillomavirus (HPV) is present in about one-third of head and neck cancers studied. The research team, led by U of L resident Payal Desai, looked at tissue samples from 43 patients with head and neck cancer of unknown origin ... "These results indicate that current vaccines, which protect against the HPV 16 virus, could prevent a large number of head and neck cancer cases," the university said in the... (Louisville Business First, KY)

    Young woman opts for double mastectomy, removal of ovaries to beat cancer threat  May 18, 2008
    It is unclear if the gene is linked to the head and neck cancer she had in 1988. Stoltz also plans to have a double mastectomy to reduce her risk of developing breast cancer a second time. (Montana Standard, MT)

    CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients  May 17, 2008
    These data confirm that CAPHOSOL is a useful tool to help oncology nurses and other healthcare professionals in the management of OM and related symptoms, particularly in patients with head and neck cancer and those receiving chemotherapy ... The rate of severe oral mucositis (NCI Clinical OM Grade 3-4) reported by head and neck cancer patients using CAPHOSOL in this study was 11% (Grade 3) and 2% (Grade 4) ... Historically, the incidence of severe OM in head and neck cancer patients receiving... (EurekAlert!)

    Imclones Erbitux BMS-099 trial not powered to show overall survival, FLEX remains pivotal registrational trial  May 16, 2008
    Erbitux is a monoclonal antibody currently approved to treat head and neck cancer and colon cancer. It is also being tested for use in non-small cell lung cancer (NSCLC), with key trial results expected at the upcoming American Society of Clinical Oncology conference in Chicago. (FT.com -- Markets)

    HPV Linked To Better Survival In Tonsil, Tongue Cancer, Study Finds  May 15, 2008
    Cancers of the tonsils and the base of the tongue have increased in recent years, in what Carey calls an "epidemic" of HPV-induced head and neck cancer. This has occurred at the same time that declines in smoking rates have led to a decrease in the incidence of other types of head and neck cancers ... About 35,300 Americans will be diagnosed with head and neck cancer this year, according to the American Cancer Society. (Science Daily)

    Does Brushing Teeth Fight Lung Cancer  May 15, 2008
    The rates went up 68 percent for head and neck cancer and 54 percent for lung cancer. The researchers also found that the more teeth someone lost, the greater the chance of cancer. (Click2Houston, TX)

    High-Tech Imaging No Better for Diagnosing Head/Neck Cancers  May 15, 2008
    TUESDAY, May 13 (HealthDay News) -- An advanced imaging technique to detect head and neck cancer may not boost a patient's odds of receiving an early or more accurate diagnosis of the disease, new findings suggest ... The findings are based on an analysis of 32 previously published studies done on head and neck cancer patients with one or fewer nodal metastases. (MEDLINEplus)

    Oncolytics Biotech Inc. Announces U.K. Phase II Clinical Trial Investigating REOLYSIN(R) in Combination with Paclitaxel and Carboplatin  May 14, 2008
    CALGARY, May 14 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that that it has received a letter of approval from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) for its Clinical Trial Application (CTA) to begin a Phase II clinical trial using intravenous administration of REOLYSIN(R) in combination with paclitaxel and carboplatin in patients with advanced head and neck cancers ... "Interim data recently presented from... (PR Newswire)

    Tooth loss strongly linked to risk of esophageal, head and neck, and lung cancer  May 14, 2008
    The researchers specifically found that people with tooth loss were 136 percent more likely to develop esophageal cancer, had a 68 percent increased risk of developing head and neck cancer and a 54 percent greater chance of developing lung cancer. The researchers also found that the rate of cancer increased proportionally to the number of teeth a patient had lost. (EurekAlert!)

    NASCAR widow's warning  May 7, 2008
    35,000 new cases of oral, head and neck cancer expected in U.S. this year ... So what is she doing at an oral, head and neck cancer screening at an Atlanta, Georgia, hospital ... The American Cancer Society estimates 35,000 new cases of oral, head and neck cancer will be diagnosed in the United States this year, accounting for between 3 and 5 percent of all cancers. (CNN -- Health)

    New Surgery Improves Head And Neck Cancer Treatment  May 2, 2008
    ScienceDaily (May 2, 2008) A new surgical procedure for head and neck cancer at the University of Alabama at Birmingham offers improved accuracy for surgeons and reduced post-operative pain for patients ... The new procedure uses robotic surgery, and results have shown it lessens the scarring, breathing problems and damage to speech that can happen with treating head and neck cancers, said William Carroll, M.D., a scientist in the UAB Comprehensive Cancer Center ... "This application takes... (Science Daily)

    Possible Viral Links to Lung Cancer Risk Uncovered  May 2, 2008
    It has also recently been implicated as a possible cause for head and neck cancer. Further studies are planned to look for signs of HPV infection in the respiratory tract of lung cancer patients and to explore the possibility for using HPV infection as a screening indicator for the disease. (MEDLINEplus)

    Health/Science calendar  Apr 21, 2008
    FRI., APRIL 25Free cancer screening Massachusetts Eye and Ear Infirmary will provide free head and neck cancer screening. From 9 a.m. to 3 p.m., Massachusetts Eye and Ear Infirmary, 11th floor, 243 Charles St. For reservations call 617-573-4084. (Boston Globe)

    HEALTH BRIEFS  Apr 16, 2008
    head, neck cancers The Oregon Health & Science University Cancer Institute will host a free head and neck cancer screening and awareness day ... Head and neck cancers affect the scalp, face, nose, mouth, throat, thyroid and neck. (OregonLive, OR -- News)

    It's Neck-and-neck Down The Long Stretch For 2 Stroke-prevention Procedures  Apr 15, 2008
    22, 2007) Giving patients with head and neck cancer a combination of chemotherapy and radiation therapy controls the cancer and allows many patients to avoid additional surgery to the neck, according to a ... (May 16, 2007) Cigarette smoking is more strongly associated with head and neck cancers than drinking alcohol, according to a new study. (Science Daily)

    DNA Paternity Test Almost Fooled: Man Put Someone Else's Saliva In His Mouth  Apr 13, 2008
    5, 2008) A morning gargle could someday be more than a breath freshener -- it could spot head and neck cancer, say scientists. Their new study of a mouth rinse that captures genetic signatures common to the. (Science Daily)

    YM BIOSCIENCES ANNOUNCES PRESENTATIONS FOR TWO OF ITS ANTI-CANCER DRUGS AT AACR ANNUAL MEETING  Apr 12, 2008
    " About YM BioSciences YM BioSciences Inc. is an oncology company that identifies, develops and commercializes differentiated products for patients worldwide. The Company has two late-stage products: nimotuzumab, a humanized monoclonal antibody that targets the epidermal growth factor receptor (EGFR) and is approved in several countries for treatment of various types of head and neck cancer; and AeroLEF(TM), a proprietary, inhaled-delivery composition of free and liposome-encapsulated fentanyl... (PR Newswire)

    Cancer Stem Cells Created With New Technique  Apr 12, 2008
    Clarke has since moved to Stanford, where he is the Karel H. and Avice N. Beekhuis Professor in Cancer Biology, and Stanford has become a leader in cancer stem cell research, with teams finding cancer stem cells in head and neck cancer, colorectal cancer and additional blood cancers. Laboratory researchers at the medical school are also beginning to work with clinical groups to apply cancer stem cell findings to patient care. (Science Daily)

    Former racer headed back to Daytona  Apr 12, 2008
    Bobby Hamilton Racing is urging fans to take part in the Oral, Head and Neck Cancer Awareness Week from April 21 to 27. More than 150 medical centers across the nation will hold free screenings. (Yahoo News -- Auto Racing)

    Ear, Nose, And Throat Specialist Joins FCMC  Apr 11, 2008
    He completed his residency at P.C.O.M., with specialty training at Buffalo General Hospital, New York, in head and neck cancer surgery and Shadyside Hospital, Pittsburgh, Pa. in advanced sinus surgery and facial nerve surgery. (Fulton County News, PA)

    Mayo Clinic identifies treatment target for liver cancer recurrence and survival  Apr 11, 2008
    In 2007, Dr. Lai presented information at the annual meeting of the American Association for Cancer Research on the role of SULF2 in survival of patients with head and neck cancer -- the first concrete link to survival of patients with a specific tumor type. . (EurekAlert!)

    Double binding sites on tumor target may provide future combination therapy  Apr 9, 2008
    Three years ago, Kate Ferguson, PhD, Assistant Professor of Physiology, and colleagues determined the precise molecular details of how Erbitux, a colorectal and head and neck cancer drug, binds to its target on cancer cells. EGFR drugs halt cell proliferation by blocking EGFRs molecular doorway, keeping hormones from binding and signaling tumor growth. (EurekAlert!)

    HPV, Periodontitis Work In Tandem To Increase Risk Of Tongue Cancer  Apr 7, 2008
    Studies conducted elsewhere have found that HPV is an independent risk factor for a subset of head and neck cancers ... If these results are confirmed by other studies, this has a tremendous relevance in predicting and intervening in the initiation and prognosis of HPV-related diseases, including head and neck cancers ... " The study involved 30 patients newly diagnosed with squamous cell carcinoma on the base of the tongue between 1999 and 2005 at Roswell Park Cancer Institute for whom data was... (Science Daily)

    'Liquor + fag = Cancer'  Apr 7, 2008
    Delivering a keynote address on the concluding day of the International Conference on Head and Neck Cancer organised under the aegis of Mahavir Cancer Sansthan (MCS) here, Dr Hosal said the government must come forward to check the growing menace of cancer in India ... The new building would be constructed on the MCS campus at a cost of Rs 8 crore to provide better medical facilities to head and neck cancer patients, he said adding about 42 per cent of the cancer patients in Bihar were suffering... (India Times, India -- Health/Science)

    Inhibition of Chemokine Receptor Activation May Improve Head and Neck Cancer Therapies, Study Suggests  Mar 27, 2008
    5 percent reduction in viability after treatment with a targeted therapy, called erlotinib, that is already being used in squamous cell head and neck cancer treatment ... (May 16, 2007) Cigarette smoking is more strongly associated with head and neck cancers than drinking alcohol, according to a new study. (Science Daily)

    Ontario ordered to pay woman's U.S. medical bills  Mar 27, 2008
    The cancer treatment offered "fell short of appropriate care for someone in her circumstances," according to the letter from Dr. Ensley, who specializes in head and neck cancer at Barbara Ann Karmanos Cancer Center. The treatment plan in Windsor might not have used the same chemotherapy drugs in the same high doses, in the same manner. (Globe and Mail)

    Identical Genes from Parents May Raise Cancer Risk  Mar 27, 2008
    So, Eng and her colleagues decided to look at 400 genetic markers scattered throughout the genome in 385 breast, prostate and head and neck cancer patients and in people without cancer. All patients were of the same ethnic group. (MEDLINEplus)

    Head and Neck Cancer Outcomes a Mixed Bag  Mar 20, 2008
    In background information in the study, the researchers noted that head and neck cancer treatment such as feeding tube placement, chemotherapy and radiation "tend to produce pain, disfigurement, eating problems and communication problems. Many patients become disabled, and about one-third of patients continue to smoke, and half are depressed.". This study by David L. Ronis, of the Veterans Affairs Ann Arbor Healthcare System and the University of Michigan School of Nursing, Ann Arbor, and... (MEDLINEplus)

    Cause Of Severe Allergic Reaction To Cancer Drug Found  Mar 17, 2008
    16, 2008) Clinicians have been perplexed by the fact that some patients given the drug cetuximab--an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer--have a severe and rapid adverse reaction to the drug ... 19, 2007) Preliminary findings show adding the chemotherapy drug cetuximab (brand name Erbitux) to radiation therapy and chemotherapy may help some patients with head and neck cancer live longer, according to. (Science Daily)

    Factors behind Head and Neck Cancer Revealed  Mar 15, 2008
    WASHINGTON (Reuters) - There are two distinct culprits behind head and neck cancer -- the long-recognized heavy tobacco and alcohol use as well as a common sexually transmitted virus, researchers said on Tuesday. The risk factors are so dramatically different in head and neck cancer in people infected with the human papillomavirus, or HPV, that it should be considered a separate disease from cases in which patients are not infected, researchers at Johns Hopkins University in Baltimore said ...... (MEDLINEplus)

    All The Wrong Numbers  Mar 15, 2008
    Thursday, Amgen shares surged 5% as advisers told the Food and Drug Administration to warn patients not to use the company's top-selling anemia drug for head and neck cancer, breast cancer or in any case where patients might be cured of their cancer by chemotherapy. Investors had expected worse. (Forbes -- Business)

    Amgen, J&J Anemia Treatments May Face U.S. Restrictions as Cancer Medicine  Mar 7, 2008
    The FDA urged doctors a year ago to use the lowest doses possible after dangers were seen in patients with kidney disease and head and neck cancer. An advisory panel is scheduled to discuss the new studies next week. (Bloomberg -- US)

    Chemotherapy in Unresectable Head and Neck Cancer  Mar 6, 2008
    To the Editor: Radiotherapy alone in patients with advanced head and neck cancer is not the treatment of choice, even when cisplatin, fluorouracil, and docetaxel (TPF) are given ... 25 issue)1 report that TPF improved progression-free and overall survival in patients with unresectable head and neck cancer, but their results are disappointing as compared with chemoradiotherapy2,3 or radiotherapy with cetuximab ... 4 In the same issue, Posner et al. also report better results in patients with... (New England Journal of Medicine)

    EU Commission Approves Updated Prescribing Information for Aranesp(R)  Mar 5, 2008
    ESA trials have shown an unexplained excess mortality in association with high target hemoglobin concentrations (greater than 12 g/dL), including (1) shortened time to tumor progression in patients with advanced head and neck cancer receiving radiation therapy; (2) shortened overall survival in patients with metastatic breast cancer receiving chemotherapy; (3) increased risk of death when administered to target a hemoglobin of 12g/dL (7. 5 mmol/l) in patients with active malignant disease... (BusinessWire)

    PET/CT planning beneficial for head and neck cancer patients  Mar 5, 2008
    That study was the largest randomized trial of radiation therapy in locally advanced head and neck cancer. Disease free survival for the 42 study patients was 71 percent and 66. (EurekAlert!)

    Drug For Anemic Cancer Patients Raises Risk Of Death, Study Shows  Feb 29, 2008
    Lai, a head and neck surgeon, saw a significant effect when he added an ESA called erythropoietin to head and neck cancer cells in tissue culture. "We saw a dramatic change," Lai said. (Science Daily)

    Study Finds Variations in Doses of Radiation Therapy  Feb 28, 2008
    Twelve percent of the participants had brain cancer, 26 percent had head and neck cancer, while 62 percent had prostate cancer. The patients were treated at five different medical centers, each using different planning systems for the therapy. (MEDLINEplus)

    Study finds increased risk of death from anemia drugs  Feb 27, 2008
    One option that analysts expect to be discussed at the meeting in March would be to bar the use of the drugs for specific types of cancer, like breast cancer and head and neck cancer. Another would be to delay treatment with the drugs until patients became more anemic than the current threshold, a change that would more closely match the Medicare reimbursement policy. (International Herald Tribune)

    Genmab Agrees to Buy Minnesota Biotech Manufacturing Plant from ...  Feb 22, 2008
    Diseases targeted by its products include leukemias, lymphomas, rheumatoid arthritis, and head and neck cancer. Genmab's antibodies also have potential for treatment of many other diseases. (FOXBusiness)

    HPV-Positive Head and Neck Cancers Fare Better  Feb 14, 2008
    TUESDAY, Feb. 12 (HealthDay News) -- Head and neck cancer patients whose tumors test positive for human papillomavirus (HPV) tend to survive longer and respond better to treatment than those who test negative, a new study says. HPV, a common virus with strains believed to be responsible for most cervical cancers, has recently been linked to the development of some head and neck cancers, particularly those of the upper throat, or oropharynx. (MEDLINEplus)

    Vitamin A And Zinc Supplement May Help Protect Children From Malaria, Study Suggests  Feb 8, 2008
    3, 2007) Zinc sulfate, a supplement thought to be helpful in regaining the sense of taste for some head and neck cancer patients after radiation therapy, has been found to have no significant impact on. (Oct. (Science Daily)

    Viventia Biotech to Explore Strategic Alternatives - Reports Positive Pivotal Phase III Interim Efficacy Data  Jan 29, 2008
    Proxinium(TM) is undergoing a global pivotal Phase 3 trial (the 'TARGET' trial) in approximately 300 patients with advanced head and neck cancer ... Proxinium(TM) Viventia's lead drug, Proxinium(TM), is a humanized antibody fragment conjugated to the cytotoxic protein Pseudomonas exotoxin A. The drug is in a global pivotal Phase 3 clinical trial (the 'TARGET' trial) in patients with advanced head and neck cancer ... Viventia's lead product, Proxinium(TM), is undergoing a global Phase 3 clinical... (Canada Newswire)

    Exelixis CEO says planning pivotal trials and partnerships this year  Jan 18, 2008
    XL880 is a small-molecule MET inhibitor in Phase II for papillary renal cell carcinoma, gastric cancer and head and neck cancer. Scangos said more renal and gastric cancer data are expected at ASCO.. (FT.com -- Markets)

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