ATL1101 suppresses tumours in prostate cancer animal study Oct 15, 2008
"Importantly, ATL1101 injection inhibited both aspects of tumour growth." "To our knowledge, this is the first demonstration of systemic efficacy in a prostate cancer model with an RNA-silencing IGF-I receptor drug. Our study clearly shows that ATL1101 is an effective inhibitor of IGF-IR signalling in vivo, and that its pharmacological mechanism is highly relevant in the control of prostate tumour growth." ANP CEO, Mark Diamond said "This project is a very exciting opportunity for ANP. By our... (Sydney Morning Herald)
X-rays could tell Chinese Olympic gymnasts' ages, scientists says Aug 23, 2008
The science of determining age is has been honed by decades of treating patients with growth disorders, identifying youthful homicide victims and determining the deportation status of illegal immigrants. "It would be relatively easy," said Dr. David Senn, a forensic odontologist at the University of Texas Health Sciences Center who has analyzed numerous X-rays of immigrants apprehended at the border. (Los Angeles Times)
Structural Biology Spin-out Tackles Major Diseases Aug 15, 2008
Their initial experiments involved fusing different elements of hormone and receptor in order to treat a growth disorders such as short stature (a deficiency in growth hormone). Professor Ross continued: "Our patented and versatile therapeutic platform technology ProFuse TM, could also tackle major diseases such as some cancers, anaemia, infertility and diabetes. Under normal circumstances hormones of the type known as cytokine hormones - growth hormone for example - circulate in the blood and... (Science Daily)
Are your hormones killing you? Jun 22, 2008
Diabetes mellitus, thyroid diseases (Hypo and hyperthyroidism), obesity, PCO, hirsutism (beard like hair on the face of a lady) growth disorders, early or late puberty, infertility, impotency, osteoporosis, pituitary and adrenal gland diseases. Setting the hormones right. (India Times, India)
HGH bill altered in order to help children Apr 16, 2008
Because doctors specializing in childhood growth disorders often are far from patients, such controls could have caused hardship for families with children using the drug ... Groups such as the Magic Foundation, a non-profit that provides support for families dealing with children with growth disorders, mobilized its members. (USA Today -- Sports)
Why Do Rats Die Younger Than Humans? Newly Discovered Biological Clock Provides Tantalizing Clues Apr 7, 2008
Future research will assess whether there is a link between slower growth rhythms and growth disorders. Since the autonomic nervous system controls human behavior, future research will also assess whether growth rhythms can be linked to variations in human behavior. (Science Daily)
Growth Hormone Found To Have New Role In Development Of Brain's Smell Center Mar 28, 2008
The hormone, insulin-like growth factor (IGF), is well-known to biomedical researchers and has been tested as a therapy for diabetes and some growth disorders. Until now, decades of research have turned up only one solid role for IGF, however, and that is to makes cells grow and multiply. (Science Daily)
Does growth hormone improve strength and athletic performance? Mar 24, 2008
While parents of children with growth hormone deficiencies support stiffer penalties for abusers, they worry their access to the drug may be limited, according to the Magic Foundation, a group dedicated to helping children with growth disorders. JUDY FOREMAN. (Boston Globe)
Debate over 'little people' intensifies After recent island discovery Mar 20, 2008
In previous reports and interviews, other skeptical scientists have contended that the extremely small brain size of the Flores people, close to that of a chimpanzee, was more likely a consequence of any number of growth disorders. Teuku Jacob, an Indonesian paleoanthropologist who was one of the first to examine the Flores bones, immediately suspected microcephaly, a genetic condition causing a small head. (International Herald Tribune -- Health)
The way kids grow, age by age Mar 15, 2008
Most growth disorders are diagnosed by pediatricians, not parents, but sometimes a child who isn't growing normally can slip through the cracks. According to a study in the Archives of Disease in Childhood, about 70 percent of all kids are measured inaccurately at their checkups. (CNN)
Health briefs for Oct. 1 Oct 2, 2007
Clinical focuses include diabetes, thyroid disease, adrenal dysfunction, reproduction, bone/mineral/metabolism, growth disorders, pediatric endocrinology and juvenile diabetes. The new clinic will have a comprehensive range of diagnostic services available. (Rapid City Journal, SD)
New research sheds light on 'hobbit' Sep 21, 2007
The distinctive shapes of wrist bones form during the first trimester of pregnancy while most pathologies and growth disorders do not begin to affect the skeleton until well after that time. Therefore, pathologies or growth defects cannot adequately explain why a modern human would have a wrist that was indistinguishable from that of an African ape or primitive hominin. (EurekAlert!)
More of this story Sep 18, 2007
Marvelle said the goal in starting the fundraiser was to help families with children who have Turner syndrome or other growth disorders ... All of the proceeds benefit the children of the Magic Foundation, a nonprofit organization dedicated to individuals who suffer from physical growth disorders ... For more information about Turner syndrome or other growth disorders, visit www. (Newport Daily News, RI)
British Scientists Discover 'Height Gene' Sep 4, 2007
Very rare mutations that cause growth disorders have been pin-pointed before, but not genes that influence normal variation. The gene was found by the same British team that discovered FTO, the first common gene known to contribute to obesity. (Fox News)
Aging: Disease or Business Opportunity? Apr 15, 2007
Under federal law, the substance is illegal to use except for treating childhood growth disorders, AIDS and a rare adult hormone deficiency. But Dr. Klatz and Dr. Goldman have argued that aging is a disease that causes the pituitary gland to gradually produce less growth hormone. (Shoals TimesDaily)
Drugs at the center of the probe Mar 7, 2007
Synthetic HGH is typically used by physicians to treat growth disorders, but athletes often abuse the drug to build muscle and decrease fat, usually in conjunction with anabolic steroids. The generic name for synthetically produced HGH is somatropin; brand names include Genotropin and Saizen. (SportsIllustrated.CNN -- More)
