Treating Stomach Infection May Cut Cancer Risk May 28, 2008
It's known to cause stomach ulcers, and in some people it can eventually lead to gastric cancer ... The investigators acknowledge that most clinical trials in patients have not noted an overall reduction in pre-cancerous lesions or actual gastric cancer in patients receiving H. pylori eradication therapy ... "This suggests that significant improvement of gastric lesions and reduction of gastric cancer prevalence may not be observed during the first few years after treatment.". (Newsmax)
Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker May 28, 2008
The objective of this study was to evaluate the efficacy and toxicity of infusional 5-fluorouracil (5-FU), folinic acid and oxaliplatin (modified FOLFOX-6) in patients with advanced gastric cancer (AGC), as first-line palliative combination chemotherapy. We also analyzed the predictive or prognostic value of germline polymorphisms of candidate genes associated with 5-FU and oxaliplatin. (BioMed Central)
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population May 16, 2008
Inherited genetic factors such as E-cadherin (CDH1) promoter variants are believed to influence the risk towards sporadic diffuse gastric cancer (DGC). Recently, a new regulatory region essential for CDH1 transcription has been identified in CDH1 intron 2. (BioMed Central)
Treating bacteria that cause ulcers may also stop tumors May 12, 2008
STOMACH CANCER Treating Helicobacter pylori - the bacterium notorious for causing ulcers in the stomach - probably helps prevent gastric cancer, new research suggests ... In the worst case scenario, long-standing gastritis can evolve to gastric cancer, which may require surgery, chemotherapy, or radiation for treatment ... Dr. James Fox and colleagues from MIT decided to test whether they could prevent gastric cancer by eradicating H. pylori. (Boston Globe)
Treating Stomach Infection Early Protects against Cancer May 6, 2008
FRIDAY, May 2 (HealthDay News) -- Prompt treatment of a common stomach infection reverses the damage that can lead to gastric cancer, according to tests on mice done by researchers at the Massachusetts Institute of Technology (MIT) ... "We concluded that H. pylori eradication prevented gastric cancer to the greatest extent when antibiotics were given at an early point of infection, but that eradication therapy given at a later point also delayed the development of severe lesions that can lead to... (MEDLINEplus)
Micromet, Inc. to Host Conference Call and Webcast to Discuss First Quarter 2008 Financial Results May 3, 2008
MT110 is the second BiTE antibody in clinical trials, and is being developed by Micromet in a phase 1 clinical trial for the treatment of patients with lung and gastric cancer. The third clinical stage antibody is adecatumumab, also known as MT201, a human monoclonal antibody which targets epithelial cell adhesion molecule (EpCAM)-expressing solid tumors. (PR Newswire)
Scientists Discover How Stomach Tumors Form May 2, 2008
WEDNESDAY, April 23 (HealthDay News) -- Scientists say they may have discovered how tumors develop in the stomach, a finding that could lead to new treatments for gastric cancer. In a study done on mice, scientists at the Melbourne Branch of the International Ludwig Institute for Cancer Research (LICR) found that blocking the signaling pathway of the IL-11 protein -- either through genetic manipulation or with medications -- would prevent certain inflammation, hyperplasia (an abnormal increase... (MEDLINEplus)
Roche Sales Fall 4% as Governments Stop Stockpiling Tamiflu Influenza Pill Apr 17, 2008
Roche is working on a late-stage trial of Herceptin against gastric cancer and will also test the drug against bladder tumors. Herceptin and Avastin have helped the company grow faster than rivals such as who face increased competition from cheaper generic drugs. (Bloomberg -- Europe)
Biomarkers Allow Doctors To Match Therapy To Patient Apr 16, 2008
8, 2007) Physician-scientists believe identifying a genetic "fingerprint" could help predict which specific therapies will be most effective for patients with gastric cancer. This trial addresses what the. (Science Daily)
Postoperative Chemotherapy Does Not Improve Survival In Gastric Cancer Patients, Study Suggests Apr 1, 2008
31, 2008) The use of combination chemotherapy following surgery did not improve survival in patients with gastric cancer, according to a randomized clinical trial ... The only potentially curative therapy currently available for non-metastatic gastric cancer is surgery ... Recent studies have suggested that a combination of cisplatin, epirubicin, 5-fluorouracil and leucovorin (PELF) improves outcome in patients with metastatic gastric cancer. (Science Daily)
Post-Op Chemo Fails to Boost Survival in Stomach Cancers Mar 15, 2008
Currently, surgery is the only treatment that can potentially cure non-metastatic gastric cancer, according to background information in the study. However, some recent research has suggested that a chemotherapy combination of cisplatin, epirubicin, 5-fluorouracil and leucovorin (PELF) improves outcomes in people with metastatic gastric cancer ... In this study, researchers tested the PELF combination in patients with localized gastric cancer. (MEDLINEplus)
Low cholesterol linked to stomach cancer risk Feb 23, 2008
"With respect to gastric cancer, a limited number of studies suggest this inverse association, while others do not." ... Gastric cancers developed in 97 subjects ... For example, among subjects with the highest cholesterol levels, the gastric cancer rate was the equivalent of 2. (Scientific American)
10 Foods That Fight Disease Feb 23, 2008
A diet rich in spinach, kale, collard greens, beet greens and romaine lettuce can protect against gastric cancer, heart attack, and stroke. Leafy greens can lower your risk of cataracts and protect your eye health. (Suite101.com)
David Borrelli, psychiatrist beloved by patients; at 59 Feb 22, 2008
He died Feb. 9 in Massachusetts General Hospital, less than a year after being diagnosed with a rare gastric cancer. Dr. Borrelli was 59 and had lived in Needham most of his life. (Boston Globe)
Optimal band imaging with endoscopy facilitates the diagnosis of depressed-type early gastric cancer Feb 19, 2008
February 18, 2008 A study from the Jichi Medical University in Japan shows that optimal band imaging used with an endoscope provided images that clearly identified depressed-type early gastric cancer without magnification in 96 percent of study participants ... Gastric cancer is one of the most prevalent types of cancer in the world ... If gastric cancer is found early, the five-year survival rate increases nearly 90 percent. (EurekAlert!)
Tricky Virus Exploits Host Cell Mechanism To Convert Healthy Cell Into Cancer Cell Jan 19, 2008
EBV-associated cancers include lymphomas (cancer of the lymph nodes), nasopharyngeal carcinoma and gastric cancer. A protein encoded by the virus, the latent membrane protein 1 (LMP1), is required for the uncontrolled proliferation of EBV-infected cells and, thus, the formation of cancer. (Science Daily)
Gastric Cancer Survivors Should Be Aware Of Osteoporosis Jan 18, 2008
17, 2008) Gastric cancer is one of the most common cancers in the world. Although the prognosis of gastric cancer is known to be poor, the survival rate for those who receive operative treatment is increasing recently by virtue of early diagnosis and aggressive surgical intervention ... Dr. Jong-Inn Lee, an expert in gastric cancer surgery in Korea, found many surviving patients complained of back pain. (Science Daily)
Exelixis CEO says planning pivotal trials and partnerships this year Jan 18, 2008
XL880 is a small-molecule MET inhibitor in Phase II for papillary renal cell carcinoma, gastric cancer and head and neck cancer. Scangos said more renal and gastric cancer data are expected at ASCO.. (FT.com -- Markets)
Exelixis fills pipeline, but still no drug Dec 24, 2007
The drug, now in Phase II trials, also may treat gastric cancer and head and neck cancer. It is one of 12 compounds that Exelixis is moving through the clinic, a rich number compared with many biotechs. (San Francisco Business Times, CA)
Getting the test: Family confronts its genetic heritage Dec 23, 2007
The threat in their case was hereditary diffuse gastric cancer, a cancer that hides in the stomach and forms small tumors scattered like needles in a haystack ... Scott Weissman, a genetics counselor at the hospital, had a hunch McNamara might have hereditary diffuse gastric cancer, a rare condition identified only seven years earlier ... Seventy percent of people with the mutation develop hereditary diffuse gastric cancer by the age of 75, research shows. (Seacoast New Hampshire)
Female Hormones May Affect Risk of Stomach Cancer Dec 22, 2007
"Hormonal factors may affect gastric cancer risk," Dr. Neal D. Freedman told Reuters Health, "but future studies are required to determine whether or not this is the case.". Freedman from the National Cancer Institute, Rockville, Maryland, and colleagues examined the association between reproductive and menstrual factors and gastric cancer risk in a large study of 74,442 women from Shanghai, China ... Later age at menopause was associated with a markedly reduced risk of gastric cancer, the... (MEDLINEplus)
Glaxo opts to pick up Exelixis cancer compound Dec 15, 2007
GlaxoSmithKline (NYSE: GSK) said it exercised an option to exclusively license XL880, a compound in Phase II trials to treat patients with papillary renal cell carcinoma -- a type of kidney cancer -- gastric cancer and head and neck cancer. A $35 million milestone payment to South San Francisco-based Exelixis will be applied to an advance that GSK paid Exelixis in 2005. (San Francisco Business Journal)
Face to face with mortality: Local resident gives first-person account of colon cancer battle Dec 5, 2007
Orientals who live in the Far East have a high incidence of gastric cancer and a low incidence of colon cancer, Hoppin said. Whereas Oriental-Americans who live in Hawaii or the mainland USA have the reverse, suggesting an influence of the western diet. (Mattoon Journal-Gazette, IL)
* Surgeon presents promising results of cancer research Dec 2, 2007
A Taiwanese surgeon yesterday suggested that more comprehensive surgical procedures increased the long-term survival chances of advanced gastric cancer sufferers. Gastric cancer is the second most prevalent cancer and the fifth most common cause of cancer-related deaths in the world, said Wu Chew-wun (d), convenor of the Taipei Veterans General Hospital's division of general surgery, at the 11th Annual Meeting of the Taiwan Cooperative Oncology Group in Taipei ... Wu presented the results... (Taipei Times, Taiwan -- World)
How can we know early who will benefit from tumor target therapy? Nov 22, 2007
Reference: Sun L, Ye HY, Zhang YH, Guan YS, Wu H. Epidermal growth factor receptor antibody plus recombinant human endostatin in treatment of hepatic metastases after remnant gastric cancer resection ... World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection for... (EurekAlert!)
New versions of curry ingredient to fight cancer Nov 7, 2007
Like curcumin, the two synthetic versions may be able to fight other cancers, such as gastric cancer and cancer of the breast, pancreas and lung, they added. Reuters2007All rights reserved. (Reuters UK)
Curry-derived molecules might be too spicy for colorectal cancers Nov 5, 2007
In addition to colorectal cancer, the catenin-degrading abilities of these molecules could apply to other forms of cancer, such as gastric cancer, said Shibata. Like curcumin, these analogues also down-regulate a number of gene products, such as NF-kappa B, ErbB2, K-ras, that are also implicated in breast, pancreas and lung cancers among other diseases. (EurekAlert!)
Chemo Drug Improves Stomach Cancer Survival for Japanese Patients Nov 1, 2007
"This is the third large study that demonstrates a significant benefit of adjuvant (combination) therapy either before or after surgery for gastric cancer," said Dr. Manish Shah, an assistant attending oncologist at Memorial Sloan-Kettering Cancer Center in New York City ... Metastatic means that the gastric cancer has spread outside the stomach, establishing microscopic colonies beyond the reach of surgery ... "For gastric cancer, since 2001, some kind of adjuvant therapy has been given here in... (Forbes)
Adjuvant Chemotherapy for Gastric Cancer with S-1, an Oral Fluoropyrimidine Nov 1, 2007
Background Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer ... Methods Patients in Japan with stage II or III gastric cancer who underwent gastrectomy with extended (D2) lymph-node dissection were randomly assigned to undergo surgery followed by adjuvant therapy with S-1 or to undergo surgery only. (New England Journal of Medicine)
East Meets West in the Treatment of Gastric Cancer Nov 1, 2007
Gastric cancer is a leading cause of illness and death from cancer worldwide, with nearly a million new cases diagnosed each year and a 5-year survival rate of less than 20% among patients in most parts of the world other than Japan, where the rate is closer to 60. 1 Early dissemination of the disease through the lymphatic system, blood, and peritoneum has limited the ability of optimal surgery to cure, except in patients with relatively early tumors. (New England Journal of Medicine)
Close Relationship Between H. Pylori And Gastric Cancer Suggested Oct 31, 2007
As a definite carcinogen, the role of Helicobacter pylori (H pylori) in the formation of gastric cancer has been unclear. An article to be published on November 7 in the World Journal of Gastroenterology reveals a new mechanism explaining the promotional effect of H pylori on gastric cancer ... However, the change of GJIC in H pylori-associated gastric cancer has been little exploited. (Science Daily)
The seed of south Augusta Oct 29, 2007
The gastric cancer claimed Jane Gunter in May 2005. If that wasn't enough, there was a Department of Transportation audit and a lawsuit to deal with. (The Augusta Chronicle)
Roche Third-Quarter Sales Rose 5.7 Percent on Demand for Cancer Treatments Oct 16, 2007
The Swiss drugmaker is working on a late-stage trial of Herceptin in the treatment of gastric cancer. The company also intends to test the drug against bladder tumors. (Bloomberg -- Europe)
Trial Seeks 'Genetic Fingerprint' For Predicting Drug Effectiveness Oct 9, 2007
University of Cincinnati (UC) physician-scientists believe identifying a genetic fingerprint could help predict which specific therapies will be most effective for patients with gastric cancer ... Syed Ahmad, MD, is leading a national, phase-2 trial to test the effectiveness of combined chemotherapy and radiation therapy given to patients with gastric cancer before surgery ... Everyone agrees that without surgery, gastric cancer in not curable, and numerous studies have shown a benefit to... (Science Daily)
Sanofi's Taxotere gets US approval for use in head and neck cancer Oct 2, 2007
Taxotere is now currently approved in five different cancer types in Europe and the US to treat breast cancer, lung cancer, prostate cancer, gastric cancer and head and neck cancer. More than 640,000 people worldwide are diagnosed with head and neck cancer each year, and more than 350,000 die from the disease annually. (MarketWatch)
A Man with Gastric Cancer and Lung Nodules Sep 21, 2007
NEJM -- Case 29-2007 -- A 51-Year-Old Man with Gastric Cancer and Lung Nodules ... Case 29-2007 A 51-Year-Old Man with Gastric Cancer and Lung Nodules ... Dr. Allison L. McDonough (Internal Medicine): A 51-year-old man with a history of gastric cancer was admitted to the hospital because of a new pulmonary lesion. (New England Journal of Medicine)
Targeting nerve growth factor may cure liver cancer Sep 19, 2007
World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection for providing a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation... (EurekAlert!)
More young women suffering from breast cancer Sep 6, 2007
" Data from the hospital shows there was a 2.3 percent increase in the number of breast cancer cases, to 439 in 2006 from 334 in the previous year. The number accounted for around 30 percent of all cancer cases in the hospital. Breast cancer is the second most prevalent cancer in Indonesia after cervical cancer. Globally, according to a 2006 report by the World Health Organization, breast cancer is the fifth most common fatal cancer after lung cancer, gastric cancer, liver cancer and colon... (Jakarta Post, Indonesia -- City)
Police start exercise program Sep 5, 2007
Nationwide, heart disease, gastric cancer, diabetes and obesity are up among aging police officers, Burch said. There is a direct link between physical fitness and the use of sick days, Burch said. (Suffolk News Herald, VA)
Real time contrast enhanced ultrasonography (CEUS) in detection of liver metastases from gastrointestinal cancer Sep 4, 2007
A total of 109 patients with colorectal (n=92) or gastric cancer prospectively underwent conventional US evaluation followed by real time CEUS and computed tomography (CT) scan. A diagnosis of metastases was made by CT or, for lesions not visibile at CT, the diagnosis was achieved by histopathology or by a malignant behavior during follow-up. (BioMed Central)
Specific H. Pylori Strains Are Associated With Precancerous Lesions Aug 31, 2007
A new study suggests that previous estimates of the risk of gastric cancer following infection with the bacterium Helicobacter pylori may be too low ... But many people with H. pylori infections never develop gastric cancer ... Some evidence suggests that genetic variation among different strains of the bacteria may explain why some infections result in gastric cancer while others do not. (Science Daily)
Stomach Cancer Rate Set To Fall Further 25 Percent Over Next Decade Aug 15, 2007
On the basis of these trends, the authors calculate that new cases of gastric cancer will fall by "at least 24%" over the next decade in the West, without the need for treatment. The authors say that the fall in the number of cases of gastric inflammation caused by Helicobacter pylori infection largely explains the figures. (Science Daily)
Garlic and Health Jul 22, 2007
For instance, residents of Gangshan province in China consume an average of 20g of garlic each day and were found to have a relatively low gastric cancer death rate of 3. 45 per hundred thousand. (Suite101.com)
Helicobacter Pylori Treatment Jul 18, 2007
In addition, according to Ables et al., it is not recommended that H. pylori be eradicated to prevent gastric cancer in asymptomatic patients because of the lack of guidelines and good-quality clinical trials. In other populations, such as patients with undifferentiated dyspepsia and children, special considerations need to be taken to detect the cause of symptoms and underlying pathophysiology. (Suite101.com)
Barium Meal and Swallow Jul 13, 2007
Gastric cancer diagnosis when gastric cancer is suspected, your physician may order a barium meal as part of your workup ... Gastric cancer screening gastric cancer is one of the common cancers affecting both men and women ... The use of a barium meal as a possible option for gastric cancer is being evaluated. (Suite101.com)
Immortalization of Cancer Cells Jul 6, 2007
These include measuring levels in the peritoneal fluid for gastric cancer and cervical tissue for cervical cancer ... Da MX, Wu XT, Guo TK, et al. Clinical significance of telomerase activity in peritoneal lavage fluid from patients with gastric cancer and its relationship with cellular proliferation. (Suite101.com)
What's old is news again Jun 24, 2007
In an April 26 filing, his lawyer informed the court that Adkins had been diagnosed with gastric cancer, and was living "hour to hour" without hope of recovery. On May 1, records show, the aging crack slinger died young, at 52. (Boston Globe -- Local)
Gene Has Strong Ties to Stomach Cancer Jun 5, 2007
SUNDAY, June 3 (HealthDay News) -- Canadian researchers say they've identified genetic mutations linked to a form of stomach cancer called hereditary diffuse gastric cancer ... Hereditary diffuse gastric cancer (HDGC) is caused by mutations in the gene CDH1 ... Of the 38 families in the study, 26 families had at least two gastric cancer cases, with one case of HDGC in a person younger than age 50; 12 families had either a single case of HDGC in a person younger than age 35 or multiple cases of... (MEDLINEplus)
S-1, a Novel Oral Fluoropyrimidine, When Combined With Cisplatin, Demonstrates Significant Improvement in Overall Survival of Advanced Gastric Cancer Patients Over S-1 Alone Jun 4, 2007
Positive results of the "SPIRITS" Study Reported in Oral Presentation at ASCO 2007 CHICAGO, June 3 /PRNewswire-FirstCall/ -- Taiho and sanofi-aventis announced today the results of a phase III trial in advanced gastric cancer, which shows that the combination of the investigational oral fluoropyrimidine S-1 with cisplatin significantly reduces the risk of death by 22 ... "This study demonstrates that the combination of S-1 and cisplatin brings to the patient with advanced gastric cancer an... (PR Newswire)
Sanofi says S-1 drug combo helps stomach cancer patients Jun 4, 2007
6 percent in advanced gastric cancer patients who received the combination treatment over S-1 alone in a Phase III Japanese study, the companies said ... "This study demonstrates that the combination of S-1 and cisplatin brings to the patient with advance gastric cancer an acceptable benefit/risk ratio," said study investigator Dr. Hiroyuki Narahara. (Scientific American)
Genetic mutations identified for type of gastric cancer Jun 4, 2007
Researchers have identified novel genetic mutations that are linked to hereditary diffuse gastric cancer, with these mutations being due to both independent mutational events and common ancestry, according to a study in the June 6 issue of JAMA. This study is being released early to coincide with its presentation at the annual meeting of the American Society of Clinical Oncology. According to background information in the article, gastric cancer is the second most common cause of cancer death... (EurekAlert!)
Results of VEGF Trap (Aflibercept) Highlighted at ASCO 2007 Annual Meeting Jun 3, 2007
The ongoing single-agent studies of aflibercept (VEGF Trap) will be complemented by a large Phase III program combining aflibercept (VEGF Trap) with standard chemotherapy regimens in five different advanced solid tumors: colorectal, non-small cell lung, prostate, pancreas and gastric cancer. Sanofi-aventis plans to make a first registration submission to regulatory agencies as early as 2008 for the VEGF Trap. (PR Newswire)
Sanofi says VEGF-Trap can help in ovarian cancer Jun 3, 2007
Final Phase III clinical trials are under way, studying afilbercept in combination with traditional chemotherapy in colorectal, non-small cell lung, prostate and gastric cancer and filing for marketing approval should take place in 2011, according to Sanofi. Aflibercept was well tolerated with typical side effects of anti-angiogenic drugs, such as hypertension, Sanofi said. (Scientific American)
Osteoblastic flare in a patient with advanced gastric cancer after treatment with pemetrexed and oxaliplatin: implications for response assessment with RECIST criteria Jun 1, 2007
A 43 year-old man with advanced gastric cancer was enrolled in a phase II trial where he was treated with pemetrexed 500 mg/m2 plus oxaliplatin 120 mg/m2 every 3 weeks. At baseline, the target lesions were lymph-nodes, and the non-target lesions were small pulmonary nodules. (BioMed Central)
High-salt diet link to ulcer risk May 24, 2007
Presenting the results at the American Society for Microbiology conference, the researchers said research had shown salt was linked to gastric cancer ... The bacterium may also increase the risk of gastric cancer ... Study leader Dr Hanan Gancz and colleagues said it was known that people who ate a high-salt diet had an increased risk of gastric cancer but no one had looked specifically at the effects of salt on H. pylori itself. (BBC News -- Health)
Stopping The Spreading Of Tumours: A Possible New Therapy May 23, 2007
All mutations were known to cause hereditary diffuse gastric cancer and reduce E-cadherin adhesion abilities but only those cells with extracellular mutations showed abnormal motility with random increased movement. As suspected, it was found that only the mutations in the extracellular part of E-cadherin affected the interaction with EGFR confirming that this as the area where contact occurred. (Science Daily)
Remove your stomach, reduce the risk of cancer May 4, 2007
Of those who carry the mutated gene, 70 per cent develop gastric cancer ... Since 2002, when Ms. Hansford's sister, Arleen, died from gastric cancer, doctors have found the mutant CDH1 gene in Ms. Hansford, her older brother, Glen, and their mother, who also tested positive for the cancer ... Dr. Huntsman and his international collaborators also believe that the gene mutation may lead to lobular breast cancer, which also seems to plague families with higher incidences of gastric cancer. (Globe and Mail)
Study of Genetic Cause of Stomach and Breast Cancers Among 78 New Projects Announced by Canadian Cancer Society May 2, 2007
Gastric cancer is extremely difficult to diagnose and is usually incurable once it is advanced enough to be detected ... For patients at risk of gastric cancer, that might mean a preventive stomach removal, a strategy that has already proved successful in preventing the disease in more than 50 people. (Canada Newswire)
New Study Links Stomach Microbe To Asthma Prevention Apr 25, 2007
(At the same time, the incidence of peptic ulcers and gastric cancer has declined in developed countries. . (Science Daily)
Daily Aspirin May Reduce Cancer Risk Apr 19, 2007
In the study, Dr. Stefano Cascinu, from the Universita Politecnica delle Marche in Ancona, Italy, and colleagues randomly assigned 397 high-risk gastric cancer patients to either eight weekly treatments of five chemotherapy drugs or six monthly treatments of only two of the drugs. Cascinu's team found no significant difference in survival between the two groups. (MEDLINEplus)
Fat 'counters vitamin C benefits' Apr 9, 2007
Nitrite, which is present in saliva and comes from nitrate in our diet, is thought to be able to trigger gastric cancer. When it is swallowed and enters the acidic environment of the stomach, nitrite spontaneously forms nitrosating species, and these are able to convert a range of other stomach chemicals into potential cancer-causing agents called N-nitrosocompounds. (BBC News -- UK)
Fat overrides effects of vitamin C Apr 2, 2007
Nitrite, which is present in our saliva and is derived from nitrate in our diet, is thought to be a pre-carcinogen for gastric cancer. When it is swallowed and enters the acidic environment of the stomach, nitrite spontaneously forms nitrosating species able to convert a range of targets, such as secondary amines and bile acids, into carcinogenic N-nitrosocompounds. (EurekAlert!)
Vitamin may cut cancer risk Feb 28, 2007
BEIJING, Feb. 28 -- High intakes of vitamin A apparently reduce the risk of developing gastric cancer, Swedish researchers report ... Results from epidemiologic studies of vitamin A, retinol in relation to gastric cancer risk have been inconsistent ... During that time, 139 cases of gastric cancer were diagnosed. (Xinhuanet, China)
Vitamin A May Reduce Stomach Cancer Risk Feb 27, 2007
NEW YORK -- High intakes of vitamin A apparently reduce the risk of developing gastric cancer, Swedish researchers report ... "However, epidemiologic studies of vitamin A, retinol (preformed vitamin A), and provitamin A carotenoids in relation to the risk of gastric cancer have documented inconsistent results." ... During that time, a total of 139 cases of gastric cancer were diagnosed. (Newsmax)
EU panel backs Novartis' mock-up pandemic flu vaccine Feb 24, 2007
Xeloda (capecitabine), from Roche Registration Ltd, to extend the indication to include first-line treatment of patients with advanced gastric cancer in combination with a platinum-based regimen. Xeloda was first authorised in the European Union on 19 October 2000 and is currently authorised for the treatment of patients with colon cancer, metastatic colorectal cancer and locally advanced or metastatic breast cancer. (MarketWatch)
