Early Data Presented at ASCO Show Potential of RAD001 to Enhance Efficacy of, and Overcome Resistance to, Breast Cancer Treatments Jun 2, 2008
Other less commonly reported side effects include vaginal bleeding, blood clots, other cancers, osteoporosis, stroke, heart attack and endometrial cancer. In the extended adjuvant setting, commonly reported side effects are generally mild to moderate. (PR Newswire)
Crackdown on 'natural' hormone remedies Jun 1, 2008
The growing popularity of a range of untested pharmacy-produced treatments, which have been linked to eight deaths in the US and three endometrial cancer cases in Australia, has alarmed health authorities. The most prolific pharmacy-produced remedies are the "natural" hormone treatments, also called bioidentical hormones, which have been heavily marketed to menopausal women as a safe alternative to conventional hormone replacement therapy, despite not having to comply with federal health... (Sydney Morning Herald -- Australia)
NYP/Weill Cornell physician-scientists present latest cancer findings at ASCO meeting Jun 1, 2008
Dr. Brian Slomovitz will present results from a Phase II clinical trial (during an oral presentation) showing that the orally administered experimental drug RAD001, a mammalian target of rapamycin (mTOR) inhibitor, is beneficial in patients with recurrent endometrial cancer. The drug blocks the activity of the mTOR protein within the cytoplasm of cancer cells, responsible for cancer cell proliferation and growth. (EurekAlert!)
Long-term Hormone Replacement Therapy Increases Breast Cancer Risk Until 5 Years After Use, Study Finds May 30, 2008
18, 1997) To help protect against endometrial cancer, women who take estrogen replacement therapy should also take progestin at least 10 days a month, say researchers at the University of. (May 9, 2006) Long-term estrogen therapy may be related to a higher risk of breast cancer among postmenopausal women who have had a hysterectomy, according to an article in the May 8 issue of Archives of Internal. (Science Daily)
UCSD researchers show link between vitamin D status, breast cancer May 16, 2008
The third, on endometrial cancer, was published Sept. 16, 2007, in Preventive Medicine. Authors on the new study are Cedric F. Garland, Dr. P.H., Frank C. Garland, Ph. (EurekAlert!)
Duncan gives MD Anderson $35 million for cancer fight May 15, 2008
Different kin of Jan Duncan also had ovarian, breast and endometrial cancer. The experience led the couple in 2006 to give Baylor College of Medicine $100 million for its cancer center, renamed the Dan L. Duncan Cancer Center. (Houston Chronicle)
IUDs Seen to Reduce Cancer Risk May 9, 2008
WASHINGTON (Reuters) - Intrauterine devices are not only among the most effective contraceptives, but they also can help protect women from a cancer of the uterus called endometrial cancer, researchers reported on Tuesday ... "IUD use among women is associated with a 40 percent reduction in the risk of endometrial cancer, similar to the cancer protection provided by oral contraceptives, yet many clinicians are not aware of that," Grimes said in a statement ... The hormones also help prevent... (MEDLINEplus)
A systematic review of tests for lymph node status in primary endometrial cancer May 6, 2008
The lymph node status of a patient is a key determinate in staging, prognosis and adjuvant treatment of endometrial cancer ... This study systematically reviews the accuracy literature on sentinel node biopsy; ultra sound scanning, magnetic resonance imaging (MRI) and computer tomography (CT) for determining lymph node status in endometrial cancer ... MRI and sentinel node biopsy have shown similar diagnostic accuracy in confirming lymph node status among women with primary endometrial cancer... (BioMed Central)
One Step Closer To Understanding The Causes Of Sexual Difficulties In Women Apr 18, 2008
17, 2007) Significant sexual problems often are an unexpected -- and unwelcome -- side effect of the treatment of early-stage cervical and endometrial cancer for many women following hysterectomy. A targeted. (Science Daily)
Los Angeles Sues Anthem Blue Cross Over Dropped Policies Apr 17, 2008
Blue Cross dropped the 61-year-old Palm Desert real estate agent last December after she had a hysterectomy for endometrial cancer that the health plan had approved in advance. Thompson was left with about $160,000 in medical bills and without insurance for the first time in her life. (Free Internet Press)
5-year-old gene-based research institution fights for funding Apr 16, 2008
Mike Gartside works on projects dealing with melanoma and endometrial cancer at the Translation Genomics Research Institute, which is seeking funding to become a bigger force in Phoenix's medical-research industry. More on this topic. (AZCentral -- Business)
Scans Spot Hidden Tumors In Rare Cancer Syndrome Mar 22, 2008
3, 2006) A new study suggests that women with endometrial cancer should be screened for inherited mutations that could lead to a high risk of several other cancers. The study showed that 1. (Science Daily)
Drug cuts risk of breast cancer returning Mar 15, 2008
Tamoxifen also raises the risk of death from strokes and endometrial cancer. But more than half of breast cancer recurrences and deaths occur five or more years after completing tamoxifen. (MSNBC -- Health)
Was the promotion of HRT as an elixir of life a triumph of ... Mar 9, 2008
Users of the combined pill (oestrogen plus progesterone) also showed lower risks for endometrial cancer. By the mid1990s researchers had claimed that HRT could reduce the risks of Alzheimer s, age-related macular degeneration, colon cancer, tooth loss, diabetes, Parkinson s disease and osteoporosis. (Times Online)
Cancer Risk Slightly Higher For Women In Discontinued Hormone Treatment Trial Mar 8, 2008
A summary of the risks and benefits (called the global index) included outcomes for coronary heart disease, invasive breast cancer, stroke, pulmonary embolism, endometrial cancer, colorectal cancer, hip fracture and death due to other causes ... The rates of colorectal cancer did not differ significantly between the two groups and rates of endometrial cancer were lower in the estrogen plus progestin group ... 18, 1997) To help protect against endometrial cancer, women who take estrogen... (Science Daily)
High Levels Of Estrogen Associated With Breast Cancer Recurrence Mar 7, 2008
6, 2008) Women whose breast cancer came back after treatment had almost twice as much estrogen in their blood than did women who remained cancer-free -- despite treatment with anti-estrogen drugs in a majority of the women -- according to researchers in a study published in the March issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research. The findings suggest that high levels of estrogen contribute to an increased risk of cancer... (Science Daily)
Common Variations In Gene Segments That Increase The Risk For Prostate Cancer Mar 3, 2008
The region discovered on chromosome 7 contains a gene that may be related to endometrial cancer. On chromosome 11, researchers found a region of significance in a gene-poor region of the DNA, resembling the finding from May 2007 on chromosome 8. (Science Daily)
Hormone Replacement Therapy Appears To Have No Effect On Risk And Severity Of Rheumatoid Arthritis Mar 2, 2008
18, 1997) To help protect against endometrial cancer, women who take estrogen replacement therapy should also take progestin at least 10 days a month, say researchers at the University of. . (Science Daily)
Pill may prevent cancer Feb 26, 2008
The pill can also offer protection against endometrial cancer, researchers found. For college women, it can be tough to find time to fit in a visit to a gynecologist or women's health professional; however, UHS offers many types of oral contraceptives without an exam. (Daily Collegian, PA)
An Increased Body Mass Index Linked To Several Cancers Feb 19, 2008
In women, the risk of endometrial cancer was increased by 59 percent, gallbladder cancer by 59 percent, oesophageal adenocarcinoma by 51 percent and kidney cancer by 34 percent. In men, weaker but significant increases in risk were associated with rectal cancer and malignant melanoma. (Medical News Today)
AEterna Zentaris Reports First Patients Treated with Anti-Cancer Compound AEZS-108 in Phase 2 Trial in Ovarian and Endometrial Cancers Feb 12, 2008
This open-label, non-comparative multi-center Phase 2 trial will treat up to 82 women with LHRH-receptor positive ovarian and endometrial cancerous tumors ... The trial will include up to 82 patients (up to 41 with a diagnosis of platinum-resistant ovarian cancer and up to 41 with disseminated endometrial cancer) ... About ovarian and endometrial cancer Ovarian cancer is one of the most common gynaecologic malignancies and the fifth most frequent cause of cancer death in women, with most of the... (Canada Newswire)
The Pill and Ovarian Cancer Feb 9, 2008
It was previously known that oral contraceptives provide long-lasting protection against endometrial cancer. While the Pill has been associated with a small increase in the risk of breast and cervical cancers, this risk goes away when women stop taking oral contraceptives. (Suite101.com)
Synthetic Estrogens Could Lessen Risks Associated With Hormone Replacement Therapy, Study Suggests Feb 7, 2008
8, 1999) Women whose breast cancer is treated with tamoxifen face a heightened risk for endometrial cancer, with that risk compounded in women who also have received estrogen replacement therapy or who are ... 18, 1997) To help protect against endometrial cancer, women who take estrogen replacement therapy should also take progestin at least 10 days a month, say researchers at the University of. (Science Daily)
The pill appears to protect against ovarian cancer Jan 28, 2008
WHAT'S NEXT: Beral's group wants to look at the effect of the pill in reducing endometrial cancer risk. WHERE TO FIND IT: The Lancet, Jan. 26. (Boston Globe)
Birth Control Pill Protects Against Ovarian Cancer Jan 27, 2008
The Pill also causes long-lasting protection against endometrial cancer (cancer or the lining of the womb) but causes a short-lived increase in breast cancer and in cervical cancer (cancer of the neck of the womb). Co-author Sir Richard Peto, Professor of Epidemiology at Oxford University, said: Young women don t have to worry about cancer from taking the Pill because the eventual reduction in ovarian cancer is bigger than any increase in other types of cancer caused by the Pill. (Science Daily)
Further Breakthroughs For Breast Cancer Patients Jan 20, 2008
19, 2008) Researchers at the Tenovus Centre for Cancer Research at Cardiff University have made a breakthrough in breast cancer treatment that could help save the lives of women who become resistant to breast cancer drugs such as tamoxifen. While drugs such as tamoxifen have been a huge success in treating breast cancer, for a significant proportion of sufferers the drugs either fail to work, or after an initial successful response the patient relapses as the cancer acquires or possesses... (Science Daily)
Combined Hormone Replacement Therapy Increases Risk Of Lobular Breast Cancer Fourfold After Just 3 Years Of Use Jan 16, 2008
18, 1997) To help protect against endometrial cancer, women who take estrogen replacement therapy should also take progestin at least 10 days a month, say researchers at the University of. (Feb. (Science Daily)
Acrylamide In Food Linked To Breast Cancer Jan 16, 2008
It should also be noted that a new Dutch study shows an association between acrylamide in foods and ovarian and endometrial cancer. It is, however, important to stress that neither study indicates an unambiguous association between acrylamide in foods and cancer. (Science Daily)
High Meat Consumption Linked to Heightened Cancer Risk Dec 11, 2007
And the research team noted an unexpected effect of red meat on endometrial cancer: the more red meat women consumed, the less likely they were to suffer from endometrial cancer ... "We really see this study that it further illustrates the complexity and challenges of understanding research related to diet and cancer. They also could have said red meat is protective of endometrial cancer. The challenges of looking at diet and cancer are just vast," said Mary K. Young, vice president for... (Health-Finder)
Lifestyle And Cancer Prevention: Making Choices That Change Cancer Risk Dec 10, 2007
8, 2007) Postmenopausal women consuming two or more alcoholic beverages a day may double their risk of endometrial cancer, suggests a new study. The study also found that the association of alcohol intake and. (Science Daily)
Carcinogen In Cooked Food Linked To Ovarian And Endometrial Cancer Dec 6, 2007
Cancer / Oncology News. Featured ArticleMain Category: Article Date: 05 Dec 2007 - 11:00 PST. (Medical News Today)
A new world of choices Dec 5, 2007
May decrease risk of endometrial cancer ... May decrease risk of endometrial cancer. (San Diego Union-Tribune)
Cooked food 'can cause ovarian or womb cancer in women' Dec 4, 2007
The researchers found that women who had eaten 40 mg of acrylamides a day (found, for example in a 32 g pack of crisps) had double the risk of endometrial cancer and ovarian cancer than women in the lowest category. "It is important that these results are corroborated and confirmed by other studies before far-reaching conclusions can be drawn," Hogervorst was quoted as saying. (Hindu)
Excess sun may lower risk of a uterine cancer Nov 29, 2007
Women in the sunniest countries seem to get endometrial cancer less often than those who live far from the equator ... The researchers assembled information on endometrial cancer in 107 countries ... They also found that higher rates of meat eating, per capita health expenditure and the percentage of the population that was overweight were each associated with a higher risk of endometrial cancer. (International Herald Tribune -- Health)
Effects Of Progesterone On Alzheimer's Disease Nov 29, 2007
Progesterone also is known to counteract the increased risk of endometrial cancer from estrogen therapy, which is one reason most women receive both hormones. Pike said his group's study should provide guidance for the design of human trials studying hormone therapy and Alzheimer's. (Science Daily)
Deficiency of sunlight exposure may raise endometrial cancer risk Nov 22, 2007
org) -- Deficiency in exposure to sunlight particularly ultraviolet (UVB), meaning low vitamin D level, may increase risk of endometrial cancer, according to a new study by researchers at the Moores Cancer Center at the University of California- San Diego ... "This is the first study, to our knowledge, to show that higher serum levels of vitamin D are associated with reduced risk of endometrial cancer," said Cedric F. Garland, Dr. P.H., professor of Family and Preventive Medicine in the UCSD... (Food Consumer)
A tough pill to swallow Nov 21, 2007
Most compellingly, studies have found that a woman who takes oral contraceptives for at least five years has about a 50 percent decrease in her lifetime risk of developing ovarian and endometrial cancer. Many women are prescribed birth control pills for their ability to regulate menstrual cycles, while others find they help curb PMS symptoms. (The Cavalier Daily, VA)
Deficiency In Exposure To Sunlight Linked To Endometrial Cancer Nov 17, 2007
16, 2007) Using newly available data on worldwide cancer incidence, researchers at the Moores Cancer Center at University of California, San Diego (UCSD) have shown a clear association between deficiency in exposure to sunlight, specifically ultraviolet B (UVB), and endometrial cancer ... Approximately 200,000 cases and 50,000 deaths from endometrial cancer occur annually worldwide, including 41,000 new cases and 7,400 deaths in the United States ... "This is the first study, to our knowledge,... (Science Daily)
Global view shows link between endometrial cancer and vitamin D status Nov 15, 2007
Using newly available data on worldwide cancer incidence, researchers at the Moores Cancer Center at University of California, San Diego (UCSD) have shown a clear association between deficiency in exposure to sunlight, specifically ultraviolet B (UVB), and endometrial cancer ... Approximately 200,000 cases and 50,000 deaths from endometrial cancer occur annually worldwide, including 41,000 new cases and 7,400 deaths in the United States ... This is the first study, to our knowledge, to show that... (EurekAlert!)
Sarah Wernick; wrote women's health bestsellers Nov 12, 2007
She was 64 and was diagnosed with endometrial cancer in 2005. In a story for Woman's Day, she wrote about her own struggle to get fit. (Boston Globe)
Contraceptive risks Nov 10, 2007
But other studies have also shown that it protects against ovarian cancer, endometrial cancer, acne ... A recent study of 00004000 around 46,000 women found a slight reduction in total cancer risk in women who used birth control (the reduced risk of ovarian and endometrial cancer is generally thought to outweigh the increased risk of cervical cancer and breast cancer). (Nature News Service)
Study: Obesity increases risk of cancer in women Nov 8, 2007
According to the study, half of the 6,000 cases of endometrial cancer (cancer of the womb) diagnosed in Britain each year are caused by the patient being overweight or obese. "Our research also shows that being overweight has a much bigger impact on the risk of some cancers than others. Two thirds of the additional 6,000 cancers each year due to being overweight or obesity would be cancers of the womb or breast," she added. (Xinhuanet, China)
Excess Pounds Raise Women's Cancer Risk Nov 7, 2007
Specifically, obese and overweight women were twice as likely to develop endometrial cancer and cancer of the esophagus compared with normal weight women. In addition, overweight and obese women had a 53 percent greater risk of kidney cancer, a 50 percent greater risk of multiple myeloma and a 24 percent greater risk of pancreatic cancer compared with their normal weight counterparts. (Health-Finder)
Overweight and obesity cause 6,000 cancers a year in UK women Nov 7, 2007
Increasing body mass index was associated with an increased incidence of all cancers combined and for 10 out of the 17 specific types of cancer examined: endometrial cancer, adenocarcinoma (malignant tumor) of the oesophagus, kidney cancer, leukaemia, multiple myeloma, pancreatic cancer, non-Hodgkins lymphoma, ovarian cancer and, in some age groups, breast and colorectal cancer ... The data also show that menopausal status is a key factor in the relation between body mass index and risk of... (EurekAlert!)
* Stay trim and no bacon, cancer report says Nov 2, 2007
Excess body fat is not only a trigger for endometrial cancer, but also oesophagus, pancreatic, bowel, post-menopausal breast, and kidney cancers, according to the report. And fat around the abdomen is also linked to bowel cancer. (Taipei Times, Taiwan -- World)
Scientist find link between body fat and cancer risk Nov 1, 2007
Previously, "high body mass" was found to be a likely cause of endometrial cancer - cancer of the womb lining ... There is also a probable connection between body fat and gall bladder cancer, and abdominal fat and pancreatic, post-menopausal breast, and endometrial cancer, the evidence suggests. (Independent)
Randall Forsberg, founder of the nuclear freeze movement, dies Nov 1, 2007
template_bastemplate_bas By Elaine Woo, Los Angeles Times Staff Writer November 1, 2007 Randall Forsberg, who founded the nuclear freeze movement of the early 1980s and wrote its manifesto, died Oct. 19 of endometrial cancer at a New York City hospital. She was 64. (Los Angeles Times)
Cervical and Uterine Cancers Oct 26, 2007
However, more common is uterine cancer, in its more usual form also called endometrial cancer - which affects the lining of the womb that grows, is shed, and regrows as part of a woman's monthly cycle. Anybody who is sexually active should be having regular smears. (BBC News -- Health)
Exposure To Sunlight May Decrease Risk Of Advanced Breast Cancer By Half Oct 22, 2007
8, 1999) Women whose breast cancer is treated with tamoxifen face a heightened risk for endometrial cancer, with that risk compounded in women who also have received estrogen replacement therapy or who are. (Dec. (Science Daily)
Low-fat diet may lower ovarian cancer risk Oct 10, 2007
Dr. Prentice, from the Fred Hutchinson Cancer Research Center in Seattle, and colleagues examined the occurrence of ovarian cancer, endometrial cancer, breast cancer, and total invasive cancer in 48,835 women randomly assigned to receive the Dietary Modification intervention or a usual diet ... The Dietary Modification intervention did not affect the risk of endometrial cancer, but may have slightly reduced the risk of breast cancer and total invasive cancer. (Scientific American)
More Fiber, Less Fat Help Prevent Ovarian Cancer Oct 10, 2007
There was no such effect on the risk of endometrial cancer, however, the researchers added. That was surprising, Morgan said, because some experts theorize that fat increases estrogen levels in the body, which, in turn, may boost risk for both ovarian and endometrial cancer. (Health-Finder)
High white cell count may predict cancer: study Oct 4, 2007
ADVERTISEMENT (article continues below) Women with the highest WBC counts had a 15 percent higher risk of breast cancer, 19 percent higher risk of colorectal cancer, 42 percent higher risk of endometrial cancer, and 63 percent higher risk of lung cancer than did women with the lowest WBC counts, the authors report. Death from breast cancer, colorectal cancer, and lung cancer was higher among women with the highest WBC counts (compared with women with the lowest), the investigators say, as was... (Scientific American)
How to avoid breast cancer Oct 3, 2007
Tens of thousands of women will have developed breast cancer, ovarian cancer and endometrial cancer (of the lining of the womb) as a result. Overall, women currently taking HRT are 63 per cent more likely to develop these three cancers than those who are not. (Independent)
Booze could raise cancer risk Oct 1, 2007
A study involving Hawaii finds greater risk of endometrial cancer in post-menopausal women ... An average of two or more alcoholic drinks a day may double the risk of endometrial cancer for post-menopausal women, a study of Hawaii and Los Angeles women indicates ... People were concerned about the risks of alcohol consumption for endometrial cancer because it does affect breast cancer, said Dr. Laurence Kolonel of the University of Hawaii Cancer Research Center. (Honolulu Star-Bulletin)
Drinking linked to endometrial cancer risk Sep 21, 2007
Older women who drink two or more alcoholic beverages a day may have an elevated risk of endometrial cancer, a new study suggests. Endometrial cancer begins in the lining of the uterus, and certain factors that raise a woman's lifetime exposure to estrogen are thought to contribute to the disease ... Obesity, late menopause and early beginning of menstruation have been linked to a heightened risk of endometrial cancer. (MSNBC -- Health)
Sex After Cancer Sep 19, 2007
Significant sexual problems often are an unexpected -- and unwelcome -- side effect of the treatment of early-stage cervical and endometrial cancer for many women following hysterectomy ... Sexual problems are associated with treatment of early-stage cervical and endometrial cancer in more than half of the women who undergo hysterectomy even though no similar association exists when hysterectomy is performed to treat benign conditions, such as fibroids ... Brotto and Heiman's study involved 19... (Science Daily)
Alcohol a cancer risk for women Sep 19, 2007
Women who have more than two alcoholic drinks a day double their risk of endometrial cancer compared with those who drink less, a new study finds ... In that time, the team found 324 cases of endometrial cancer, the type that forms in the tissue that lines the uterus ... According to the National Cancer Institute, the United States has 40,000 new cases of endometrial cancer a year and 7,400 deaths. (International Herald Tribune)
Breast Cancer Drug Tames Acute Mania in Bipolar Disorder Sep 14, 2007
The researchers acknowledge that tamoxifen is unlikely to become the drug of choice because it may cause endometrial cancer if taken for extended periods. However, they noted, by pointing to protein kinase C as a target for new medications, the study raises the possibility of developing faster-acting treatments for the often-destructive early manic phase of the illness. (MedPage Today)
Breast cancer pill helped bipolar mania: study Sep 13, 2007
Tamoxifen blocks some of the effects of the hormone estrogen and can raise the risk of endometrial cancer in women. "We now have proof of principle. Our results show that targeting PKC directly, rather than through the trickle-down mechanisms of current medications, is a feasible strategy for developing faster-acting medications for mania," Manji said in a statement. (Scientific American)
Cancer survivors to model in Relay for Life fund-raiser Sep 12, 2007
Thomas was diagnosed with endometrial cancer, or cancer of the uterine lining. On April 23, 2001, she underwent successful surgery to remove the cancer and has been cancer-free ever since. (Waynesboro Record Herald, PA)
Study says pill prevents cancer Sep 12, 2007
And they are significantly less likely to suffer from certain other cancers, in particular ovarian cancer and endometrial cancer, which affects the lining of the womb. They are also better protected from bowel cancer. (Guardian Unlimited -- UK)
Manic phase of bipolar disorder benefits from breast cancer medication Sep 12, 2007
Tamoxifen itself might not become a treatment of choice, though, because it also blocks estrogen the property that makes it useful as a treatment for breast cancer and because it may cause endometrial cancer if taken over long periods of time. Currently, tamoxifen is approved by the Food and Drug Administration for treatment of some kinds of cancer and infertility, for example. (EurekAlert!)
Women Drinkers Have Higher Cancer Risk Sep 11, 2007
Endometrial Cancer Most Common Reproductive Cancer ... Older women who have two or more alcoholic drinks a day have double the risk of endometrial cancer, a new study said ... Endometrial cancer affects the lining of the uterus. (Click2Houston, TX)
Health Highlights: Sept. 8, 2007 Sep 9, 2007
"Previous studies have shown that alcohol consumption has been associated with higher levels of estrogens in postmenopausal women, which could be the mechanism by which daily alcohol intake increases ones risk of endometrial cancer," Veronica Wendy Setiawan, assistant professor of preventive medicine at USC's Keck School of Medicine, says in the news release. The researchers used a huge database of more than 215,000 people developed in 1993 by Dr. Brian Henderson, dean of the Keck School of... (Forbes)
Frequent Alcohol Consumption Increases Cancer Risk In Older Women Sep 9, 2007
Postmenopausal women consuming two or more alcoholic beverages a day may double their risk of endometrial cancer, suggests a study led by researchers at the University of Southern California (USC) ... "This is the first prospective study to report a significant association between alcohol and endometrial cancer," says Veronica Wendy Setiawan, assistant professor of preventive medicine at the Keck School of Medicine of USC. "Previous studies have shown that alcohol consumption has been associated... (Science Daily)
