Sernova Corp.: New Strategic Plan Apr 29, 2009
His research training and experience includes biochemical pharmacology, diabetes, oncology, inflammatory diseases (psoriasis, multiple sclerosis, surgical adhesions, Alzheimer's disease and rheumatoid arthritis), osteoarthritis, neurological diseases and cardiovascular conditions including ischemic heart disease, cardiomyopathy, hypertension and aneurysms. Dr. Toleikis will be presenting on the Corporation's behalf at the BioFinance Conference in Toronto on Wednesday, April 29, 2009. (CCNMatthews Press Releases)
Reduce Suffering, Urge Heart Failure Patients and Caregivers Apr 28, 2009
Family members who look after people with heart failure are important in the overall picture of medical care, said Dr. Gregg Fonarow, director of the Ahmanson-UCLA Cardiomyopathy Center and associate chief of the UCLA Division of Cardiology at the University of California, Los Angeles. "We recognize that patients who do well have engaged family members," Fonarow said. (MEDLINEplus)
National Occupational Therapy Month Apr 28, 2009
The title of Dr. Wang's grant is "Molecular Pathogenesis of Protein Surplus Cardiomyopathy." Other medical school investigators who are participating in the project include Drs. Doug Martin, Curt Kost and Huabo Su. (Sioux City Journal)
Surgical Ventricular Reconstruction for Heart Failure Apr 28, 2009
1 However, none of them specifically address the coronary disease responsible for ischemic cardiomyopathy and myocardial infarction. Coronary-artery bypass grafting (CABG), which was first used to ameliorate. (New England Journal of Medicine)
Want A Portuguese Water Dog? Find Out If One Is Right For You Apr 17, 2009
"We have a lot of recessive health problems that crop up like hip dysplasia, progressive retinal atrophy, juvenile cardiomyopathy, storage disease, which is a disease of the nervous system," she said. Because of their hair, owners have to brush them a few times a week, and get them groomed frequently. (W-USA News, DC)
Heart And Skeletal Muscle Inflammation: A 'New' Infectious Disease Of Atlantic Salmon Apr 15, 2009
In her doctorate, Kongtorp described the disease and compared the pathological findings to those of a number of known diseases such as pancreas disease (PD) and cardiomyopathy syndrome (CMS). Both field sampling and contact infection trials indicate that HMSI is a new disease caused by an unknown organism. (Science Daily)
Virus-Induced Myocarditis Prevented In Mice Apr 14, 2009
Moreover, the mice did not show any evidence of inflammatory cardiomyopathy. That is why Professor Gotthardt assumes contrary to previous hypotheses that the direct effects of the virus infection, and not the autoimmune response, primarily determine the disease process. (Science Daily)
Current Drug Can Treat Rare Heart Disorder Apr 13, 2009
12, 1998) The drug cyclosporin may be effective in treating hypertrophic cardiomyopathy (HCM), a heart disease cited as the most frequent cause of sudden death in young adults and young athletes, according to. . (Science Daily)
Cutler: "It's a dream come true" Apr 11, 2009
Tiana was suffering from dilated cardiomyopathy, which causes the heart to weaken and enlarge, disabling the heart's pumping system. As a result, Tillman changed the focus of his foundation from education to improving the lives of critically and chronically ill children. (BearReport.com)
'Faulty genes' Apr 10, 2009
Eventually a genetic test determined that the condition was a rare inherited heart disorder - arrhythmogenic right ventricular cardiomyopathy (ARVC). Claudia already knows she has passed the condition on to at least one of her three children. (BBC News -- Health)
Donate Life Documentary Apr 8, 2009
Donate Life: The Documentary - Health News Story - KFOX El Paso. Current conditions for local cities. (KFOXTV.com, TX)
Heart disease on the rise in India Apr 4, 2009
This protein often results in cardiomyopathy, a disease that causes deterioration of the heart muscle. Genetic mutations found within specific communities are nothing new. (CNN -- Health)
Prognosis Excellent in 'Broken Heart' Syndrome Apr 4, 2009
They created a registry of 70 patients with the syndrome, known medically as Takotsubo cardiomyopathy, who were diagnosed between July 2004 and April 2008. Two-thirds of the patients - nearly all post-menopausal women - had experienced a very stressful physical or emotional event just before arriving at the hospital with heart attack-like symptoms, including chest pain and shortness of breath. (MEDLINEplus)
Recently Identified Genetic Heart Disorder Often Deadly For Young Patients Apr 1, 2009
31, 2009) A study that included young patients with a recently recognized rare type of cardiomyopathy (a disorder of the heart muscle) linked to a genetic mutation finds that progression of this disease may be rapid and often results in early death, according to a new study ... Mutations in the lysosome-associated membrane protein gene (LAMP2; known as Danon disease) produce a cardiomyopathy in young patients that clinically is similar to severe hypertrophic cardiomyopathy (HCM; a condition in... (Science Daily)
Big heart needs rescue Apr 1, 2009
One of Boston's great advocates for the homeless suffers from cardiomyopathy. That's a scientific way of saying his heart barely pumps on its own. (Boston Globe)
Binge drinking Mar 30, 2009
Mirarchi has seen binge drinkers as young as 30 develop cardiomyopathy, an incurable heart defect. Armed with these facts, colleges have taken steps in recent years to discourage their students from binge drinking. (Erie Times-News, PA)
Medics 'can mend a broken heart' Mar 28, 2009
Broken heart syndrome, known medically as Takotsubo cardiomyopathy, was first described by Japanese researchers in the early 1990s. Even though symptoms mimic those of a heart attack such as chest pain and shortness of breath, broken heart syndrome does appear to be temporary and completely reversible - if treated quickly. (BBC News -- Health)
What Causes Mystery Heart Condition? Mar 28, 2009
Stress cardiomyopathy linked to common drugs, study finds ... THURSDAY, March 26 (HealthDay News) -- The unusual heart syndrome called stress cardiomyopathy can be triggered by some commonly used heart medications, Johns Hopkins University researchers report ... The report that they can cause stress cardiomyopathy might provide at least a partial solution to the riddle presented by the condition, said study senior author Dr. Ilan S. Wittstein, an assistant professor of medicine at Hopkins. (MEDLINEplus)
Danon Disease Can Be Quickly Fatal Mar 26, 2009
The recently recognized disease is a type of cardiomyopathy, or heart muscle disorder, linked to genetic mutations in the lysosome-associated membrane protein gene (LAMP2) ... "The clinical course of these seven patients with LAMP2 mutations provides important insights regarding molecular diagnosis as well as the natural history, pathophysiology and clinical implications of this recently recognized genetic cardiomyopathy," the researchers wrote. (MEDLINEplus)
Aastrom Biosciences Receives Notification That NASDAQ Further Extends Suspension of Certain Continued Listing Requirements Mar 24, 2009
A Phase II clinical trial with dilated cardiomyopathy (DCM) patients (the IMPACT-DCM trial) and a Phase IIb clinical trial with critical limb ischemia (CLI) patients (the RESTORE-CLI trial) are currently underway. For more information, visit Aastrom's website at. (Primezone Releases)
New Test Successfully Identifies Life-threatening Heart Disease Mar 19, 2009
18, 2009) A study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated that a new immunohistochemical test is reliable in diagnosing a dangerous arrhythmic heart disease known as arrhythmogenic right ventricular cardiomyopathy (ARVC.). See also. (Science Daily)
Health Matters: Risks associated with drinking Mar 18, 2009
Other serious problems include fetal alcohol syndrome, cardiomyopathy, cardiac arrhythmia and sudden cardiac death. If you drink alcohol, do so in moderation. (Needham Tab, MA)
New Test Seems to Spot Deadly Heart Condition Mar 13, 2009
The disease is arrhythmogenic right ventricular cardiomyopathy (ARVC), in which a genetic flaw causes the muscle cells of one of the heart's main pumping centers to be replaced by fatty deposits. The end result can be a sudden loss of regular heartbeat that is often fatal. (MEDLINEplus)
Test for ARVC Mar 12, 2009
NEJM -- A New Diagnostic Test for Arrhythmogenic Right Ventricular Cardiomyopathy ... A New Diagnostic Test for Arrhythmogenic Right Ventricular Cardiomyopathy ... Background The diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC) can be challenging because the clinical presentation is highly variable and genetic penetrance is often low. (New England Journal of Medicine)
Sudden Collapse Of Healthy Athletes May Be Due To Hereditary Cardiac Disease Mar 9, 2009
For young people in particular there is often an underlying genetic cause (cardiomyopathy) ... The genetic variant that suffers from cardiomyopathy is called "Lazy Susan" and got its nickname because of its slow blood flow ... 20, 2006) The origins of cardiomyopathy, one of the leading causes of sudden cardiac death in young adults, is explained in a recent study in mice. (Science Daily)
FDA Removes Clinical Hold From Aastrom Phase II IMPACT-DCM Clinical Trial Mar 4, 2009
The IMPACT-DCM trial is evaluating the use of Cardiac Repair Cells (CRCs), a mixture of stem and progenitor cells derived from a patient's own bone marrow, for the treatment of dilated cardiomyopathy (DCM), a severe form of chronic heart failure ... About Dilated Cardiomyopathy (DCM) ... The Company's ongoing development activities focus on applying TRC technology to cardiac and vascular tissue regeneration, and a Phase II clinical trial with dilated cardiomyopathy (DCM) patients (the IMPACT-DCM... (Primezone Releases)
New potential therapeutic target discovered for genetic disorder -- Barth syndrome Mar 3, 2009
The various symptoms of BTHS, in addition to cardiolipin deficiency, include cardiomyopathy (weakness in heart muscle), neutropenia (a reduction in neutrophils or white blood cells that fight bacterial infections), muscle weakness ue (caused by cellular deficiency), growth delay, and increase of organic acids in urine. In a previous study, NYU researchers documented the characteristics of a tafazzin-deficiency in a Drosophila (fruit fly) model of the disease, showing low and abnormal cardiolipin... (EurekAlert!)
Melton to focus on city, election Mar 1, 2009
Court documents show he is in end-stage cardiomyopathy, a serious condition that prevents the heart from properly pumping blood. His doctor has recommended a heart transplant. (The Clarion-Ledger)
Melton: Mayor's trials taking their toll Feb 26, 2009
In December, Melton's doctors told U.S. District Judge Dan Jordan the mayor was in end-stage cardiomyopathy and needs a heart transplant. Jordan delayed the trial for a month and ordered him into cardiac rehab. (The Clarion-Ledger)
An Angry Heart Can Lead To Sudden Death Feb 26, 2009
Patients who had coronary artery disease or dilated cardiomyopathy (a condition in which the heart muscle are enlarged) and a standard indication for ICD were recruited from the Yale Electrophysiology practice ... (July 25, 2007) High-risk patients with hypertrophic cardiomyopathy appear to have reduced risk of sudden cardiac death with an implantable cardioverter-defibrillator that terminates dangerous heart rhythm. (Science Daily)
Mistrial, possible retrial complicate politics Feb 25, 2009
Court documents show Melton is in end-stage cardiomyopathy, a condition that prevents the heart from properly pumping blood. Many of the candidates say they are not waiting to see how the mayor's unknowns pan out. (The Clarion-Ledger)
Jury deliberations stall Feb 22, 2009
He is in end-stage cardiomyopathy, a serious condition that prevents the heart from properly pumping blood. Jordan said the jury must determine that both men knew the unlawful purpose of the raid and willingly joined it. (The Clarion-Ledger)
Melton timeline Feb 19, 2009
Court documents later revealed Melton was in the end-stage of cardiomyopathy, a serious heart condition that prevents the heart from properly pumping blood. The documents also indicated Melton's cardiologist had recommended a transplant, but Melton declined. (The Clarion-Ledger)
It May Not be a Heart Attack Feb 19, 2009
It s called stress cardiomyopathy (car-dee-o-my-OP-a-thee) or more commonly broken heart syndrome. The initial symptoms of stress cardiomyopathy are the same ones bringing most people to the ER for a heart attack; e.g., chest pains, trouble breathing, and nausea ... Dr. Ilan Wittstein at Johns Hopkins Medical Center in Baltimore, Maryland once offered six checkpoints to help his team distinguish if the patient was suffering from stress cardiomyopathy. (Suite101.com)
Sudden Cardiac Death Rare in Young Athletes Feb 18, 2009
Cardiovascular disease killed more than half those athletes, with one in three being linked to hypertrophic cardiomyopathy, a condition that results in an enlarged heart that can often be detected by a routine electrocardiogram (ECG) ... "Indeed, the relatively low absolute number of cardiovascular sudden death events reported here in young athletes raises some doubt regarding the ambitious considerations for pre-participation screening based on the rigorous Italian model," lead author Dr. Barry... (MEDLINEplus)
Stem Cells: Politics, processes and potential Feb 17, 2009
Regenocyte Therapeutic is using adult stem cell therapy to treat congestive heart failure, cardiomyopathy, peripheral artery disease, coronary artery disease, kidney disease, ischemic heart disease, pulmonary diseases and hypertension, and early senile dementia. The U.S. Clinical Center with complete diagnostic capabilities and its own catheterization lab is located in Bonita Springs, where there are 39 employees and associates. (Naples Daily News)
Understanding Heart Failure Feb 14, 2009
Too much alcohol can result in the heart muscle becoming progressively flabby and unable to contract forcefully (Alcoholic cardiomyopathy). Symptoms of Heart Failure. (Suite101.com)
Most heart attack patients' cholesterol levels did not indicate ... Feb 13, 2009
"The study gives us new insight and intervention ideas to help reduce the number of heart attacks," said Fonarow, who is also director of the Ahmanson UCLA Cardiomyopathy Center. "This is one of the first studies to address lipid levels in patients hospitalised for a heart attack at hospitals across the entire country.". (The Virtual Medical Centre)
Broken Heart Syndrome Feb 10, 2009
Technically, it's known as stress cardiomyopathy (car-dee-o-my-OP-a-thee) ... All of these people and others are prime candidates for stress cardiomyopathy, which surfaces in about 15 to 20% of cases of long-term stress ... Ongoing emotional trauma is apparently even more of a factor than physical issues in inciting stress cardiomyopathy. (Suite101.com)
Nature Genetics Feb 8, 2009
Common risk variant for cardiomyopathy in South Asia. Kumarasamy Thangaraj and colleagues describe association of a 25-bp deletion in MYBPC3 with cardiomyopathies in individuals of South Asian ancestry. (Nature News Service)
Dying To Play Feb 8, 2009
The leading cause of sudden death in American athletes is a genetic disorder called hypertrophic cardiomyopathy, which by some estimates affects people. Like weeds that overrun an unkempt yard, the heart muscle fibers proliferate rapidly and in a disorganized manner, often leading to a tripling or quadrupling in heart size during adolescence (see a picture ). (Slate)
Cougar Football History Feb 8, 2009
An insidious heart disease known as Hypertrophic Cardiomyopathy has stalked Chuck Morrell and his family for three generations, claiming five lives and forever haunting those left behind. Cougar legend Torgy Torgeson recalls heartbreak surrounding 1950 game against the Huskies. (Cougfan.com)
Rapid Response Teams Don't Cut Hospital Heart Attacks, Death Rates Feb 7, 2009
"The evidence supporting any benefits of rapid response teams has been tenuous at best," said Dr. Gregg C. Fonarow, director of the Ahmanson-UCLA Cardiomyopathy Center at the University of California, Los Angeles. "Yet, based on recommendations to implement rapid response teams by the Institute for Healthcare Improvement, hospitals across the country have diverted substantial resources and personnel to create and staff such teams.". (MEDLINEplus)
60 Million Worldwide Carry Heart Disease Mutation Feb 7, 2009
The mutation, a deletion of 25 letters of genetic code from the heart protein gene MYBPC3, was discovered five years ago in two Indian families with a history of cardiomyopathy, an enlargement or abnormal thickening of the heart muscle that weakens the heart and reduces its ability to pump blood. The genetic risk of heart disease is expressed as an odds ratio. (MEDLINEplus)
Sisters Ages 6 and 8 Need New Hearts Mar 27, 2008
Emily Smith, 6, and Shayde Smith, 8, have been diagnosed with restrictive cardiomyopathy, a progressive disease that enlarges and hardens the heart, according to the report. The disease ultimately leads to failure. (Fox News)
Runner Shay's Death Heart-Related Mar 19, 2008
Dr. Douglas Zipes, a spokesman for the American College of Cardiology who studies sudden deaths in athletes, said previously it can be difficult to differentiate a normal athlete's heart from potentially deadly hypertrophic cardiomyopathy. Cardiac echo tests and electrocardiograms can help evaluate whether the heart is healthy or not, said Zipes, a distinguished professor at the Indiana University School of Medicine. (Time.com)
Chronic Sleep Disruption Can Cause Heart And Kidney Disease Mar 19, 2008
e. light/dark), the heart becomes damaged and enlarged (cardiomyopathy), and the kidney tubules sustain significant scarring ... The Heart and Stroke Foundation and the A. Ephraim and Shirley Diamond Cardiomyopathy Research Fund funded this study. (Science Daily)
U.S. runner died of natural causes, autopsy says Mar 19, 2008
Dr. Douglas Zipes, a spokesman for the American College of Cardiology, who studies sudden deaths in athletes, said previously it can be difficult to differentiate a normal athletes heart from potentially deadly hypertrophic cardiomyopathy ... The size wont decrease if they suffer from hypertrophic cardiomyopathy, a disease in which a portion of the heart muscle is thickened without any obvious cause ... About a quarter involved hypertrophic cardiomyopathy. (MSNBC -- Sports)
Vitamin D Lowers Diabetes Risk Mar 19, 2008
Insufficient blood levels of vitamin D have been linked to several health problems aside from rickets and type 1 diabetes, including other autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, along with some rare but serious heart problems like cardiomyopathy. Indeed a host of recent studies has shown myriad benefits of taking supplements. (Time.com)
Rare heart condition hits moms-to-be Mar 15, 2008
Richard had somehow developed a rare and mysterious form of heart failure called peripartum cardiomyopathy, which strikes pregnant women ... In 2000, the NHLBI did its best to describe peripartum cardiomyopathy despite the information vacuum. (USA Today -- News)
Patrick Swayze Has Pancreatic Cancer Mar 7, 2008
An Expert Explains the Risk Factors and Treatments for Pancreatic Cancer. (WebMD) Patrick Swayze, who starred in such blockbuster films asDirty Dancing and Ghost, has been diagnosed with pancreatic cancer , according to mediareports. (CBS News)
Story ideas from Molecular and Cellular Proteomics Mar 7, 2008
Tony Gramolini, Andrew Emili and their colleagues sought to obtain more insight into cardiomyopathy progression, so they performed a large-scale protein survey of mouse cardiac cells affected by a mutation that weakens the muscle. They compared protein profiles at 8, 16, and 24 weeks of both diseased and healthy animals. (EurekAlert!)
Enlarged Heart Rare In Top Athletes Mar 7, 2008
Study Shows Few Cases Of Hypertrophic Cardiomyopathy In Elite Athletes ... Only three of the athletes had possible signs of hypertrophic cardiomyopathy, in which heart muscle becomes dangerously thick ... The other two refused to trim their training, but other tests failed to confirm that they have hypertrophic cardiomyopathy. (CBS News)
More of this story Mar 4, 2008
The cause of Hobbs death was an enlarged heart, professionally known as hypertrophic cardiomyopathy (HCM). That was such a sad, sad situation, Anthony said. (Pine Bluff Commercial, AR)
Former Polish president Walesa gets heart device Mar 1, 2008
Doctors said he suffers from cardiomyopathy, a weakness of the heart, that could eventually require bypass surgery or a heart transplant, but they want to avoid those measures. Walesa also has diabetes, high cholesterol and sleep apnea, or irregular breathing while sleeping, and doctors have prescribed medicines and treatments to deal with each, Torre said. (Reuters)
Scientists find gene that stops hearts without warning Mar 1, 2008
Newfoundlanders aren't the only ones who suffer from Type 5 Arrhythmogenic Right Ventricular Cardiomyopathy, or ARVC. But the cluster of affected families, many of whom descend from the region's first few settlers, brought attention to the disorder after their plight was described in the New England Journal of Medicine in the 1980s. Still, ARVC is not well understood and estimates of its prevalence in the general population range from one in 1,000 people to one in 5,000. (Scripps Howard News Wire)
Science lifts veil on deadly Nfld. curse Feb 29, 2008
Newfoundlanders aren't the only ones who suffer from Type 5 Arrhythmogenic Right Ventricular Cardiomyopathy, or ARVC. But the clustering of affected families, many of whom descend from the remote island's first few settlers, brought attention to the lethal disorder after their plight was described in the New England Journal of Medicine in the 1980s. Still, ARVC is not well understood and estimates of its prevalence in the general population range from one in 1,000 people to 1 in 5,000 people. (Globe and Mail -- National)
Tennessee among schools offering heart exams Feb 29, 2008
Health officials administered the echocardiograms to search for evidence of hypertrophic cardiomyopathy, a condition blamed for the sudden death of more than a hundred athletes each year ... About a quarter involved hypertrophic cardiomyopathy, which causes an enlarged heart ... After medical monitoring ruled out cardiomyopathy, Crews was cleared to return to the lineup at Tennessee, where he is averaging 6 points and 4. (SportsIllustrated.CNN -- NCAA Basketball)
Weak hearts a danger for athletes Feb 23, 2008
Specific causes include hypertrophic cardiomyopathy, in which the heart becomes unusually thick, making it harder to pump blood, and abnormalities of coronary arteries, which can become compressed during exercise and slow blood flow to the heart. A genetic disorder known as Long QT syndrome, which affects the heart's electrical system, is another potential cause. (Globe and Mail)
Bittersweet win after athlete dies in playoff Feb 21, 2008
An autopsy on Tuesday indicated Veal's death was the result of hypertrophic cardiomyopathy a thickening of the heart muscle according to the East Baton Rouge Parish coroner's office ... Hypertrophic cardiomyopathy is the most common cause of sudden, unexpected death among young athletes, according to Dr. Kim Edward LeBlanc said. (Atlanta Journal-Constitution)
Louisiana HS star collapses, dies during game Feb 20, 2008
The most common cause of sudden, unexpected death among young athletes is hypertrophic cardiomyopathy, LeBlanc said. The condition makes it difficult for blood to leave the heart but is difficult to discern. (ESPN -- Women's Basketball)
New Guidelines: Antibiotic Prophylaxis Feb 15, 2008
The updated guidelines state that patients who have taken prophylactic antibiotics in the past but no longer need them include people with: -- Mitral valve prolapse -- Rheumatic heart disease -- Bicuspid valve disease -- Calcified aortic stenosis -- Congenital heart conditions such as ventricular septal defect, atrial septal defect and hypertrophic cardiomyopathy These revisions are based on scientific evidence that conclude that the risks of taking preventive antibiotics, such as adverse... (PR Newswire)
Santhera says ready availability of idebenone complicating clinical trial process Feb 14, 2008
He explained that a Swiss patient group, impressed by early clinical studies suggesting idebenones positive effect on cardiomyopathy a major cause of FA morbidity had approached the drugs originator, Takeda ... However, Santheras application to regulators is for a 150mg tablet, based on clinical trials suggesting that higher doses had a beneficial effect on neurological function as well as cardiomyopathy. (FT.com -- Markets)
Aastrom Reports Second Quarter Fiscal Year 2008 Financial Results Feb 8, 2008
First compassionate-use cardiac patient treatment with Aastrom's autologous stem cell therapy for dilated cardiomyopathy (DCM) ... Currently, the Company has a vascular regeneration product in clinical development for the treatment of critical limb ischemia (called the RESTORE-CLI trial), a bone regeneration product in Phase III development for the treatment of osteonecrosis of the femoral head (called the ON-CORE trial), a cardiac regeneration product in clinical development for dilated... (Primezone Releases)
Rodent study shows that chronic drinking can lead to severe pneumonia after surgery Feb 4, 2008
These patients can exhibit a higher rate of pneumonia after surgery, a higher rate of cardiomyopathy or heart muscle disease, a higher rate of confusion post surgery, and significant increased bleeding complications. In addition, some 50 percent of patients who are committed to hospitals after an accident suffered their injuries under the influence of alcohol. (EurekAlert!)
