Roche's Avastin Fails to Meet Goal of Prostate Cancer Treatment in Study Mar 12, 2010
Sutent in January 2006 became the first treatment simultaneously approved for two cancers: gastrointestinal stromal tumors, or GIST, and renal cell carcinoma. The drug, also being tested for lung and liver cancer, generated of $964 million in 2009. (Bloomberg -- Europe)
ImmunoGen product gets orphan drug status Mar 9, 2010
The special designation covers IMGN901 s use as a treatment for Merkel cell carcinoma, a rare type of aggressive cancer that develops beneath the skin. Shares of ImmunoGen rose 38 cents, or 5. (Boston Globe)
Occupational Sunlight Exposure Reduces Kidney Cancer Risk in Men, Study Suggests Mar 9, 2010
Occupational sunlight exposure and risk of renal cell carcinoma. Cancer, Published Online: March 8, 2010 DOI. (Science Daily)
Trial Launched to Test New Treatment for Pre-Invasive Breast Cancer Mar 8, 2010
This three-year clinical trial will test the effectiveness of the anti-malarial drug chloroquine in treating 90 women with ductal carcinoma in situ (DCIS), a type of breast cancer in which the cancer cells start in the milk ducts but have not yet become invasive and spread in the breast. Once the cancer cells start to spread in the breast and throughout the body, the condition is considered invasive and can often be fatal. (Science Daily)
Tanning peril Mar 7, 2010
Paige did finally see a doctor and found out she had a precancerous skin condition and the first and second most common forms of skin cancer - basal cell and squamous cell carcinoma. All three conditions were caused by sun exposure. (Ellensburg Daily Record, WA)
US doctors sanction transplant criteria for liver cancer patients Mar 6, 2010
Liver transplantation specialists recently convened to address U.S. guidelines for allocation of organs for patients with hepatocellular carcinoma (HCC, liver cancer) ... " ### Article: "Report of a National Conference on Liver Allocation in Patients with Hepatocellular Carcinoma in the United States ... " Elizabeth Pomfret, Kenneth Washburn, Michael Nalesnik, David Douglas, Christoph Wald, Mark Russo, John Roberts, David J. Reich, Myron E. Schwartz, Luis Mieles, Fred Lee, Sander Florman,... (EurekAlert!)
SIBLING Proteins May Predict Oral Cancer Mar 6, 2010
Precancerous oral lesions, which can develop in the cheek, tongue, gums and floor and roof of the mouth, are risk factors for oral squamous cell carcinoma, which accounts for over 95 percent of all oral and pharyngeal cancers ... 2, 2008) Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report in the Oct. 1, 2008, issue of Clinical Cancer. (Science Daily)
Link Between Vitamin D and Basal Cell Carcinoma Probed: Study Sheds Light on Development of Most Common Form of Skin Cancer Mar 6, 2010
5, 2010) A Henry Ford Hospital study has shown a link between Vitamin D levels and basal cell carcinoma, a finding that could lead researchers to better understand the development of the most common form of skin cancer ... Previous studies have linked Vitamin D deficiency with certain cancers but this is believed to be the first time researchers looked at Vitamin D and basal cell carcinoma ... Basal cell carcinoma, which affects about 1 million Americans a year, is the most common form of skin... (Science Daily)
Hoyer: Dems could create abortion bill to satisfy Stupak Mar 5, 2010
I was diagnosed with carcinoma in-situ 16 years ago and following my divorce 12 years ago I became self-employed. After my Cobra ran out I was able to find costly, but affordable health insurance. (TheHill.com)
Herceptin and Tykerb Effective Against a Subset of Gastric Cancers, Study Suggests Mar 4, 2010
16, 2009) A research team analyzed the differences and relevance of Yes-associated protein and survivin, and explored the correlation and significance of their expression in gastric carcinoma and precancerous. (June 11, 2008) A new study reveals a previously unidentified candidate oncogene that appears to play a significant role in a subset of prostate cancers. (Science Daily)
Coffee Associated With Reduced Risk of Hospitalization for Heart Rhythm Disturbances Mar 4, 2010
2, 2007) A new study on the relationship between coffee drinking and the risk of liver cancer (hepatocellular carcinoma) confirmed that there is an inverse association between coffee consumption and HCC. (Jan. (Science Daily)
Ghrelin mitigates liver fibrosis in animal models; regulates human fibrosis Mar 1, 2010
Liver diseases, such as hepatitis viruses, cirrhosis, and hepatocellular carcinoma (HCC, liver cancer), affect more than 5 million Americans with over 85,000 new cases of hepatitis reported annually, according to estimates from the Centers for Disease Control and Prevention (CDC). The World Health Organization reports over 2 billion people worldwide have some type of viral hepatitis. (EurekAlert!)
SLU Medical Center researchers get $42M Feb 27, 2010
1 million grant from the and Kidney Diseases for Hepatitis C Clinical Trial Clinical Centers: Prevention of Cirrhosis, Hepatic Decompensation and Hepatocellular Carcinoma in patients with Chronic Hepatitis C (HALT C). Wendi Neckameyer, professor of pharmacological and physiological science, received a $1 million grant from the for a project titled, Hormonal Factors and Recruitment of Neurons into Stress Response Circuitry. (St. Louis Business Journal, MO)
9-year-old raises more than $25k for charity event Feb 21, 2010
But right around Christmas, the cause took on a deeper meaning: Jack and his sister Meaghan, 7, learned their mother, Angie, had been diagnosed with a rare form of cancer, small cell carcinoma. That e-mail has now traveled through a wide net of support, and nearly eight weeks later, Jack has surpassed his goal and his numbers are still climbing. (Boston Globe)
Reversing Resistance to Sunitinib: Findings May Help Patients With Deadly Kidney Cancer Feb 19, 2010
19, 2010) Van Andel Research Institute (VARI) researchers have found a way to reverse resistance to sunitinib, a treatment that is currently the first line of defense against clear cell renal cell carcinoma (ccRCC), a deadly form of kidney cancer ... Renal cell carcinoma (RCC) accounts for 9 out of 10 kidney cancers, and ccRCC is the most common subtype, accounting for 8 out of 10 RCC cases ... "The research from Dr. Teh's (VARI) group is a critical step forward in understanding the mechanisms... (Science Daily)
Genomic Map Spanning Over Two Dozen Cancers Charted Feb 19, 2010
(June 17, 2009) A polyomavirus known as MCPyV is associated with clinical outcomes, including fewer metastases and better survival, in patients with a rare form of skin cancer called Merkel cell carcinoma, according. (Dec. (Science Daily)
Pistons' CEO resigns Feb 18, 2010
The veteran mentor was informed he had squamous cell carcinoma in his right tonsil in late December and that has metastasized to a lymph node in his neck, according to his physician, Dr. Jacques Saari. Always a fighter, Karl, who already beat prostate cancer nearly five years ago and watched his son, Coby, beat thyroid cancer, talked about it as "a curable and treatable disease." "My hope is that it is a curable and treatable disease," Karl said. (ABC 7 News, DC)
Researchers Find Biomarkers in Saliva for Detection of Early-Stage Pancreatic Cancer Feb 18, 2010
Pancreatic ductal adenocarcinoma, the most common type of cancer of the pancreas, is also the most lethal of all cancers, with a mortality rate that is approximately the same as the rate of incidence ... 2, 2008) Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report in the Oct. 1, 2008, issue of Clinical Cancer. (Science Daily)
Loss of Gene Function Makes Prostate Cancer Cells More Aggressive Feb 18, 2010
The study in mice, published in the Jan. 11 issue of the Proceedings of the National Academy of Sciences, found that eliminating the DAB2IP scaffolding in human carcinoma cells caused them to change from epithelial cells to mesenchymal cells -- a hallmark of metastatic cancer ... " Dr. Hsieh said identifying the DAB2IP protein in human cells might serve as a biomarker, helping physicians identify patients who could have more aggressive, metastatic forms of prostate cancer. EMT is known to play... (Science Daily)
NSAIDs Won't Shield Against Skin Cancer Feb 17, 2010
Researchers find anti-inflammatories show no effect on squamous cell carcinoma ... "Although there is some prior evidence, mostly laboratory-based, to suggest that NSAIDs can reduce the risk for the particular type of skin cancer called cutaneous squamous cell carcinoma, in our study, we didn't find that association," said the lead author, Dr. Maryam M. Asgari, an investigator in the research division at Kaiser Permanente Northern California (KPNC) in Oakland, Calif ... In fact, those patients... (MEDLINEplus)
Certain pain medications do not appear to be associated with skin cancer risk Feb 16, 2010
Laboratory studies of cells and animals have indicated that NSAIDs protect against squamous cell carcinomas, common types of cancers that appear in the upper layers of the skin. However, while some studies have examined the associations between NSAIDs and other types of cancersincluding colorectal, breast, prostate and lungfew have assessed the association between NSAID use and squamous cell carcinoma risk in human populations ... Maryam M. Asgari, M.D., M.P.H., of Kaiser Permanente Northern... (EurekAlert!)
Financial Woes Add Anxiety To Breast Cancer Diagnosis Feb 10, 2010
MONDAY, Feb. 8 (HealthDay News) -- Financial pressure puts low- and medium-income women at particularly high risk for anxiety and depression after being diagnosed with the noninvasive breast cancer ductal carcinoma in situ (DCIS), a U.S. study has found. The study included 487 women with newly diagnosed DCIS who completed questionnaires about their financial, mental and physical health at the start of the study and again nine months after diagnosis. (MEDLINEplus)
Promising Results Shown for Kidney Cancer Drug Feb 9, 2010
8, 2010) The drug pazopanib (Votrient) slowed the progression of advanced renal cell carcinoma (RCC), a form of kidney cancer, in patients by 54% percent, according to a new study published in the Journal of Clinical Oncology ... "Advanced renal cell carcinoma remains a challenging disease, but the outlook for patients has improved in the past year -- including the addition of pazopanib, which targets multiple pathways within cancer cells," study author Dr. Cora N. Sternberg, chief of the... (Science Daily)
Financial hardship contributes to diagnosis anxiety Feb 8, 2010
A new analysis has found that women with medium or low levels of income are particularly susceptible to anxiety and depression after being diagnosed with the precancerous breast condition, ductal carcinoma in situ (DCIS) ... Article: "The role of socioeconomic status in adjustment following ductal carcinoma in situ." Janet S. de Moor, Ann H. Partridge, Eric P. Winer, Jennifer Ligibel, and Karen M. Emmons. (EurekAlert!)
Many Surgeons Suffer Injuries from Minimally Invasive Techniques Feb 8, 2010
4, 2010) A research team from Hong Kong reported a case of repeated laparoscopic hepatectomy treating hepatocellular carcinoma (HCC) and its recurrence in an aged patient having cirrhosis, a disease causing. . (Science Daily)
Promoter polymorphism linked to gastric cancer Feb 3, 2010
A functional polymorphism in the DNA methyltransferase 3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma ... The aim of this study was to investigate the role of a DNMT3A promoter genetic variant on its transcriptional activity and to evaluate the association between DNMT3A gene polymorphism and the susceptibility to gastric cancer (GC) and oesophagus carcinoma (EC) in the Chinese population. (BioMed Central)
HPV Vaccine May Prevent Breast Cancer Feb 2, 2010
The researchers found the presence of high-risk HPV in 39 percent of the ductal carcinoma in situ cancers and in 21 percent of the invasive ductal carcinoma (IDC) breast cancer specimens examined. Non-invasive or in situ breast cancers are those restricted to the glands that make milk and do not spread. (Newsmax)
New Drug Slows Advanced Kidney Cancer Jan 28, 2010
The phase 3 study included 233 patients with previously untreated kidney cancer (also known as renal cell carcinoma) that was locally advanced or had spread, and 202 patients with renal cell carcinoma who had previously been treated with cytokine therapy (interferon or interleukin) ... The data from this study, published online Jan. 25 in the Journal of Clinical Oncology, was used by the U.S. Food and Drug Administration to approve pazopanib in October 2009 for the treatment of advanced renal... (MEDLINEplus)
A pragmatic approach to cancer Jan 28, 2010
He says he isn t sure what caused his lung cancer, which was classified as a squamous cell carcinoma, traditionally a type of skin cancer. Can I tell you that any one of those things caused cancer, George asked rhetorically. (Klamath Falls Herald & News, OR)
Obesity Ups Cancer Risk, and Here's How Jan 26, 2010
Given the apparent connection between obesity and liver cancer in particular, Karin's team decided to investigate in mice prone to develop hepatocellular carcinoma (HCC). The mice are typically given HCC either by exposure to a chemical carcinogen, known as DEN, when they are two weeks old, or by exposure to that same carcinogen at three months of age followed by the tumor-promoting chemical phenobarbitol. (Science Daily)
No definite timetable set for Calhoun's return to Connecticut Jan 22, 2010
He had his prostate removed in 2003 and has been treated for squamous cell carcinoma twice, most recently in the summer of 2008. "It is my recommendation that coach Calhoun take a medical leave from his coaching position to address some temporary medical issues, none of which involve any previous medical conditions that he has dealt with," University of Connecticut Health Center physician Peter Schulman, Calhoun's primary care physician, said in a statement. (Daily Orange, NY)
Tips from the journals of the American Society for Microbiology Jan 22, 2010
HCV is a highly potent viral infection that can ultimately lead to chronic hepatitis, liver steatosis, cirrhosis, and hepatocellular carcinoma. The current course of treatment against HCV includes interferon therapy (stimulating the processes within cells that slow the reproduction and growth of the virus) in conjunction with the antiviral drug ribavirin, however, the combination treatment is difficult for patients to endure and is often ineffective. (EurekAlert!)
Vets, like pet owners, struggle with issue of animal cancer Jan 22, 2010
DOLITTLER: VIEWS FROM A VET. an award-winning blog on pet health; she writes weekly for the Miami Herald and monthly for Veterinary Practice News. (USA Today -- Life)
Three Esophageal Cancer Cell Lines Commonly Used in Research Prove to Be from Other Cancers Jan 21, 2010
20, 2010) Three frequently used human esophageal adenocarcinoma cell lines used for research were confirmed as being from other tumor types, according to a brief communication published online January 14 in the Journal of the National Cancer Institute ... The 13 established esophageal adenocarcinoma cell lines are important because of the limited availability of patient samples and animal models ... Cell lines SEG-1, BIC-1, and SK-GT-5 were proven to be cell lines from other tumor types,... (Science Daily)
UConn Coach Jim Calhoun To Take Medical Leave Of Absence Jan 20, 2010
He had his prostate removed in 2003 and has twice been treated for squamous cell carcinoma, the last time in the summer of 2008. Last summer, Calhoun fell off his bike during a charity event in Simsbury, broke several ribs and fainted after the race. (FOX61, CT)
New Technique Shrinks Skin Cancers Jan 20, 2010
The researchers examined a type of skin cancer called squamous cell carcinoma, which is usually found on areas of the body that receive a lot of sun, such as the face, ears, neck, lips, and backs of hands. The cancers can be removed by simply cutting them out, curettage and electrodessication (scraping and treating with an electric needle), and cryosurgery (freezing with liquid nitrogen). (Newsmax)
Researchers Tackle Ductal Carcinoma in Situ and Its Many Unanswered Questions Jan 19, 2010
19, 2010) An article and commentary published online January 13 in the Journal of the National Cancer Institute review available data on diagnosis and management of ductal carcinoma in situ (DCIS), and offer recommendations for the field. These include identification of better risk stratification methods, consideration of the elimination of the word "carcinoma" from the name, and further investigation into whether imaging technology and guidelines can be modified to focus on high-risk lesions... (Science Daily)
The gap year continues in full force Jan 19, 2010
And she knew it was good news when the pathologist told her what type of cancer she had -- ductal carcinoma in situ, confined to one site. Kandi takes advantage of 'Housewives' success. (Fresno Bee -- Lifestyle)
Breast cancer survivors lobby lawmakers Jan 18, 2010
Betts said many forms of breast cancer, such as her own Ductal carcinoma in situ, are not detectable to the touch. As a result, she said, some tumors may be found during mammogram screenings well before a doctor has any indication cancer may be present. (Catskill Daily Mail, NY)
How Sunlight Causes Skin Cells to Turn Cancerous Jan 18, 2010
In the new study, researchers examined a type of skin cancer, called squamous cell carcinoma, that accounts for between 200,000 and 300,000 new cases per year. Squamous cell carcinoma begins in the upper part of the epidermis, the top layer of the skin ... In squamous cell carcinoma, the PKC gene is turned off. (Science Daily)
Patients with resectable esophageal adenocarcinoma benefit from neoadjuvant chemoradiotherapy Jan 16, 2010
Esophageal carcinoma (EC) is one of the major malignant diseases worldwide ... Histological subgroup analysis indicated that esophageal squamous cell carcinoma did not benefit from neoadjuvant chemoradiotherapy ... Their meta-analysis suggest that patients with esophageal adenocarcinoma (EAC) may be the real beneficiaries of the treatment protocol. (EurekAlert!)
Detection of HPV DNA in esophageal cancer specimens from different regions and ethnic groups: a descriptive study Jan 16, 2010
HPV has been found repeatedly in esophageal carcinoma tissues ... HPV L1 DNA and HPV genotypes were evaluated in 435 esophageal carcinoma specimens collected from four geographic regions with different ethnicities including Anyang in north China, Shantou in south China, Xinjiang in west China, and the United States ... HPV infection is common in esophageal carcinoma independent of region and ethnic group of origin. (BioMed Central)
Small-Cell Lung Cancer Breakthrough: MicroRNAs Key to Identifying Patients Resistant to 'First-Line' Chemotherapy Jan 14, 2010
There are three types of SCLC: small cell carcinoma (oat cell cancer), mixed small cell/large cell carcinoma, and combined small cell carcinoma ... 16, 2008) The targeted therapy gefitinib should be considered a first-line therapy for nonsmoking Asian patients with adenocarcinoma of the lung, one of the most common types of lung cancer, suggests a. (Science Daily)
Obesity Linked to Common Form of Kidney Cancer and Each Extra BMI Point Increases Risk Jan 14, 2010
Lowrance et al. Obesity is associated with a higher risk of clear-cell renal cell carcinoma than with other histologies : OBESITY ASSOCIATED WITH CLEAR-CELL RCC. BJU International, 2010; 105 (1): 16 DOI. Need to cite this story in your essay, paper, or report. (Science Daily)
Why me? Miracle cure that followed prayers to MacKillop Jan 12, 2010
She only knows that 17 years after a non-small carcinoma was found on her right lung, followed by secondary growths in her glands and brain, she is free of cancer. When she was diagnosed in 1993, her doctors gave her two months to live and she received no medical treatment because they said there was little point. (Sydney Morning Herald -- Australia)
The power of women Jan 12, 2010
And she knew it was good news when the pathologist told her what type of cancer she had -- ductal carcinoma in situ, confined to one site. Audrey Redmond: 'I had too much to live for. (Fresno Bee -- Lifestyle)
Kids Who Beat Cancer Still Face Heart Risks Jan 10, 2010
The cancers were leukemia, brain cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, kidney cancer, neuroblastoma, soft tissue carcinoma or bone cancer. The study found that young adult survivors of these childhood cancers are much more likely than others in their age group to have cardiovascular problems, including heart failure, heart attack, heart inflammation and heart valve abnormalities, for up to 30 years after being treated for cancer. (MEDLINEplus)
Genetic Test May Someday Help Spot Breast Cancer Jan 10, 2010
Pathologists can have particular difficulty discerning the difference between non-cancerous hyperplasia, or an excess of cells, and ductal carcinoma in situ, a non-invasive and highly treatable form of breast cancer. At times it can be also difficult to tell the difference between ductal carcinoma in situ and invasive ductal carcinoma, a more aggressive and life threatening form of cancer. (MEDLINEplus)
Smoking, Drinking Up Risks of Gut, Throat Cancers Jan 10, 2010
Alcohol, in contrast, affected only the risk of esophageal squamous cell carcinoma, the form found in the upper part of the esophagus ... In recent decades, the rate of esophageal adenocarcinoma, the other major form of esophageal cancer, has been rising in the U.S. and Europe ... A similar trend has been seen with gastric cardia adenocarcinoma. (MEDLINEplus)
Low Selenium Tied to Throat, Stomach Cancers Jan 10, 2010
People with the highest levels of this antioxidant mineral were at the lowest risk of developing squamous cell carcinoma of the esophagus, Dr. Jessie Steevens of Maastricht University Medical Center in The Netherlands and her colleagues found ... The researchers looked at the relationship between selenium levels and three different types of cancer: esophageal squamous cell carcinoma (ESCC), which arises from the cells lining the upper esophagus; esophageal adenocarcinoma (EAC), which begins in... (MEDLINEplus)
Cancer & Chemo Jan 10, 2010
At 41, she's had all three types of the condition: basal cell carcinoma, squamous cell carcinoma and melanoma. Ahmed Hamdi wants to be a superhero when he grows up. (CNN -- Health)
What is Basal Cell Carcinoma? Jan 10, 2010
What is Basal Cell Carcinoma ... What is Basal Cell Carcinoma ... Basal cell carcinoma is a type of skin cancer also known as rodent ulcer. (Suite101.com)
Beauty & Plastic Surgery Jan 10, 2010
At 41, she's had all three types of the condition: basal cell carcinoma, squamous cell carcinoma and melanoma. The woman who received the first-ever near-total face transplant in the United States told her doctor she has regained her self-confidence, said Dr. Maria Siemionow, head of plastic surgery research at the Cleveland Clinic and leader of the transplant team. (CNN -- Health)
