Health Highlights: Jan. 27, 2008 Jan 29, 2008
A condition called Barrett's esophagus, marked by changes in the lining of the esophagus, often precedes cancer. Detection of Barrett's esophagus can help prevent cancer. (U.S. News & World Report)
Camera In A Pill To Check Your Insides Jan 25, 2008
Esophageal cancer often follows a condition called Barrett's esophagus, a noticeable change in the esophageal lining. Patients with Barrett's esophagus can be healed, avoiding the deadly esophageal cancer ... Only a small percentage of people who get Barrett's esophagus, about 5 percent to 10 percent, develop cancer. (Science Daily)
City incubator attracts CryMed Dec 17, 2007
CryMed is working with Dr. Mark Johnston of the National Naval Medical Center to develop a patented device using low-pressure liquid nitrogen to treat patients with Barrett's Esophagus, an ailment believed to be a precursor to esophageal cancer. CryMed President Tim Askew said in a news release CryMed's technology is "moving rapidly toward commercialization.". (Baltimore Business Journal, MD)
Fruits and raw veggies reduce the risk of cancer Dec 10, 2007
In another study from a team at Ohio State University patients with a condition known as Barrett's esophagus which often leads to esophageal cancer, were given black raspberries, also called blackberries or blackcaps, which are also rich in cancer-fighting compounds. The researchers fed 32 grams of freeze-dried black raspberries to women with Barrett's esophagus and 45 grams to men, every day for a six month period. (News-Medical.net)
Diet And Cancer Prevention: New Evidence For The Protective Effects Of Fruits And Veggies Dec 8, 2007
Black raspberries modulate markers of oxidative stress in patients with Barrett's esophagus. Black raspberries may protect against esophageal cancer by reducing oxidative stress in patients with Barrett's esophagus (BE), a pre-cancerous condition that usually arises due to gastroesophageal reflux disease, report researchers at The Ohio State University. (Science Daily)
Blackberries, Broccoli Sprouts Battle Cancer Dec 8, 2007
In the first study, Ohio State University researchers found black raspberries may protect against esophageal cancer by reducing the oxidative stress that results from Barrett's esophagus, a precancerous condition usually caused by gastroesophageal reflux disease ... People with Barrett's esophagus typically are 30 to 40 times more likely to develop esophageal cancer, which has a poor five-year survival rate of 15 percent ... The team gave 32 grams to 45 grams of black raspberries daily for six... (MEDLINEplus)
Is There An Anti-Cancer Diet? Dec 7, 2007
They decided to expand the study to high-risk patients with a precancerous condition in the esophagus called Barrett's esophagus. Those with the conditionhave a 30 to 40 times higher risk of getting esophageal cancer, Kresty says. (CBS News)
3-D Model Of Esophageal Cancer Created Nov 21, 2007
(May 31, 2006) Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma) ... 6, 2007) Celecoxib, a nonsteroidal anti-inflammatory drug (NSAID), did not prevent cancer in patients with Barrett's esophagus in a placebo-controlled study, according to new research published in the April 4. (Science Daily)
Large Waistline Ups Risk of Barrett's Esophagus Sep 21, 2007
NEW YORK (Reuters Health) - Excessive abdominal fat appears to significantly increase the risk of Barrett's esophagus, a condition in which cells that line the esophagus become abnormal, which may progress to esophageal cancer, a study shows ... "In fact, these results may partially explain why men experience so much higher risk than women of developing Barrett's esophagus and esophageal (cancer)." ... Vaughan, of the Fred Hutchinson Cancer Research Center, Seattle, Washington, and colleagues... (MEDLINEplus)
Exeter area business briefs Sep 4, 2007
Technology to treat Barrett's Esophagus. People suffering from the potentially precancerous esophageal condition known as Barrett's esophagus will have access to a technologically advanced treatment through Seacoast Gastroenterology at Exeter Hospital ... The hospital's new Barrx Halo system allows for safe and minimally invasive removal of Barrett's esophagus. (Seacoast New Hampshire)
Heartburn Can Be a Sign of Serious Disease Sep 1, 2007
Left untreated, persistent heartburn/GERD symptoms can lead to severe complications such as esophageal strictures or a precancerous condition called Barrett's Esophagus. In rare cases, people with persistent heartburn/GERD develop esophageal cancer. (Health-Finder)
You can learn heart help in a hurry Aug 18, 2007
Over time, the persistent acid bath can cause normal skin-like cells in the esophagus to change into tougher, more acid-resistant cells of the type found in the stomach and intestine, a condition called Barrett's esophagus ... Adenocarcinoma of the esophagus, the cancer associated with Barrett's esophagus, is currently the most rapidly rising cancer in the United States, with a sixfold increase in cases during the past 30 years, according to the U.S. National Cancer Institute. (Globe and Mail)
Gastroesophageal Reflux Disease Aug 13, 2007
The result is called Barrett's esophagus. The significance of this is its relation to esophageal cancer. (Suite101.com)
Why Persistent Acid Reflux Sometimes Turns Into Cancer: New Clues Aug 12, 2007
In research published in July and August, scientists discovered that people with acid reflux disease, particularly those with a complication of acid reflux called Barrett's esophagus, have altered cells in their esophagus containing shortened telomeres, the ending sequences in DNA strands ... "The research supports why it is important to prevent reflux, because the more reflux you have and the longer you have it, the more it might predispose you to getting Barrett's esophagus. So you want to... (Science Daily)
Frost brings another life sciences company to Miami Jul 27, 2007
SafeStich is an early-stage company specializing endoscopic and minimally invasive surgery for gastroesophagel reflux disorder and excision of Barrett's esophagus. The company is also developing techniques for hernia repair and natural orifice transesophageal surgery. (South Florida Business Journal, FL)
Body Parts -- The esophagus: A portal May 27, 2007
However, the changed tissue, called Barrett's esophagus, is at a higher risk of becoming cancerous. Heartburn in a pregnant woman can mean something quite different: that the baby will be born with a full head of hair. (North County Times)
New Approach To Treating Precancerous Esophagus Condition May 25, 2007
The new procedure is being tested in patients with Barrett's esophagus, a condition associated with the continued reflux of stomach acids into the lower esophagus that can damage its lining over time ... There are currently two main treatments for Barrett's esophagus with high grade dysplasia ... "This approach has the potential to dramatically alter the way we treat patients with Barrett's esophagus.". (Science Daily)
Presentation of Long-term Results for Treating Barrett's Esophagus with HALO Ablation System May 21, 2007
Barrett's Esophagus Eliminated in 98 ... 4% of patients with Barrett's esophagus treated with the HALO Ablation System have no residual Barrett's esophagus tissue after a follow up period of more than two and a half years ... The presentation of these long-term clinical trial results was made at the Digestive Disease Week (DDW) meeting this week, an international meeting of more than 16,000 gastrointestinal physicians and researchers, held in Washington D.C. Barrett's esophagus is a... (PR Newswire)
Celecoxib Does Not Prevent Cancer In Barrett's Esophagus Patients Apr 7, 2007
Celecoxib, a nonsteroidal anti-inflammatory drug (NSAID), did not prevent cancer in patients with Barrett s esophagus in a placebo-controlled study, according to new research published in the April 4 Journal of the National Cancer Institute. The incidence of Barrett s esophagus a precancerous change in the lining of the esophagus that increases the risk of developing esophageal cancer is on the rise in the United States. (Science Daily)
Light-based Probe 'Sees' Early Cancers In First Tests On Human Tissue Mar 29, 2007
Wax and his former graduate student John Pyhtila reported in the March 2007 issue of Gastrointestinal Endoscopy that their fiber-optic device reliably differentiated between healthy and precancerous digestive tissue taken from the stomach and esophagus of three patients known to have a precancerous form of a condition called Barrett's esophagus. In less than a second, their fa/LCI-enhanced version of an endoscope, instruments used to visualize internal organs, provided the clinical information... (Science Daily)
Early Cancers 'Seen' By Light-Based Probe Mar 28, 2007
Wax and his former graduate student John Pyhtila reported in the March 2007 issue of Gastrointestinal Endoscopy that their fiber-optic device reliably differentiated between healthy and precancerous digestive tissue taken from the stomach and esophagus of three patients known to have a precancerous form of a condition called Barrett's esophagus. The researchers said that in less than 1 second, their fa/LCI-enhanced version of an endoscope, instruments used to visualize internal organs, provided... (Click2Houston, TX)
Blockers not a cure Mar 27, 2007
A: Yes, but let me assume that you've been tested by a gastroenterologist and are free of serious conditions, including cancer, Barrett's esophagus or ulcers. With that, I can discuss heartburn and reflux (GERD), and what I say may surprise you. (Shoals TimesDaily)
Berries May Give Anti-Cancer Boost Mar 27, 2007
Based on the findings, the scientists have begun tests in people with Barrett's esophagus (a condition of the esophagus that increases risk of esophageal cancer) and precancerous colon polyps. The results of those tests aren't yet available. (CBS News)
New Procedure Helps Prevent Esophageal Cancer Mar 9, 2007
" The condition is called GERD, which stands for gastroesophageal reflux disease. Hofmann's doctor, gastroenterologist Dr. Bob Ganz, said the valve at the top of her stomach leaks. That allows the reflux of acids from the stomach up into the throat. It is a problem plaguing about one in five adults. "About 20 million Americans, we think, have acid reflux daily," said Ganz. For five to 10 percent of them, years of reflux actually change the cells' lining the esophagus from squamous cells to... (WCCO.com, MN)
Aspirin Reduces Esophageal-cancer Risk In People With Most-aggressive Form Of Barrett's Esophagus Feb 28, 2007
Researchers at Fred Hutchinson Cancer Research Center have found that people with the most-aggressive form of Barrett's esophagus, a precancerous condition that can lead to esophageal cancer, may benefit the most from preventive therapy with aspirin, ibuprofen and other nonsteroidal anti-inflammatory drugs, or NSAIDs ... D., and colleagues in the Hutchinson Center-based Seattle Barrett's Esophagus Program, will be published in the Feb. 27 issue of PLoS Medicine, a freely available online journal... (Science Daily)
Heartburn Treatment May Increase Bile Reflux Feb 14, 2007
A new study may explain why individuals treated for acid reflux with proton-pump inhibitors (PPI) still experience reflux symptoms. Researchers from the Lynn Health Science Institute in Oklahoma City, OK, treated 15 individuals with significant complaints of heartburn, with either a PPI or with a placebo. (Science Daily)
Study Reports 70% of Barrett's Esophagus Patients Cured at One-Year Follow-Up in Multi-Center Study Feb 5, 2007
Feb. 5 /PRNewswire/ -- BARRX Medical, Inc. today announced that 70% of the patients enrolled in a multi-center clinical trial were free of a precancerous condition called Barrett's esophagus one year after treatment ... In the report titled, "Circumferential Endoscopic Ablation of Barrett Esophagus using a Balloon- Based System: One-Year Follow-up of 100 Patients," patients with Barrett's esophagus were safely treated with the HALO360 Ablation System ... Barrett's esophagus is present in more... (PR Newswire)
Esophageal Cancer Rates Climb With Obesity; Esophagectomy Found Safe In Obese Patients Feb 1, 2007
"The type of patient who currently develops esophageal cancer has changed dramatically in the last 20 years. Esophageal cancer used to be primarily squamous cell carcinoma found in people who drank alcohol and smoked excessively. In association with the horrendous epidemic of obesity in this country, we have seen a 350 percent increase of adenocarcinoma over the last 30 years. This is related to more gastroesophageal relux and Barrett's esophagus in these patients," says Mark Orringer, M.D.,... (Science Daily)
Gastro Esophageal Reflux Disease: Study Demonstrates Long-term Durability Of Endoscopic Procedure Jan 13, 2007
(May 31, 2006) -- Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma) ... (April 28, 2005) -- A new camera-in-a-pill can help doctors diagnose and evaluate diseases of the esophagus including gastroesophageal reflux disease (GERD), erosive esophagitis and Barrett's esophagus (a pre-cancerous. (Science Daily)
Acid Suppression Medication Linked With Increased Risk Of Hip Fracture Dec 28, 2006
Use of the drugs proton pump inhibitors (PPIs) for the treatment of acid-related diseases such as gastro esophageal reflux disease (GERD) is associated with a greater risk of hip fracture, according to a study in the December 27 issue of JAMA.. Potent acid suppressive medications such as PPIs have revolutionized the management of acid-related diseases. (Science Daily)
'Dua Anti-reflux Valve' Found To Improve Quality Of Life For Bile Duct-Pancreatic Cancer Patients Dec 22, 2006
Dua Anti-reflux Valve' Found To Improve Quality Of Life For Bile Duct-Pancreatic Cancer Patients. An anti-reflux valve developed to help esophageal cancer patients also has been shown to help those with bile duct obstruction, according to Kulwinder S. Dua, M.D., a research physician at the Medical College of Wisconsin in Milwaukee. (Science Daily)
What Cures Your Aches Might Prevent Cancer: Seeking To Prevent Cancer Using Anti-inflammatory Medication Dec 22, 2006
Other gastroenterologists at Mayo are looking at NSAID use for patients with Barrett's esophagus. "There is evidence to support the idea that taking an NSAID will slow or reverse precancerous conditions such as Barrett's esophagus," Dr. Limburg says ... (May 31, 2006) -- Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma). (Science Daily)
EndoGastric Solutions(TM) Announces 80% Success Rate of Their Endoluminal Fundoplication (ELF) Procedure Using the EsophyX(TM) Device for the Treatment of GERD Dec 8, 2006
Reflux of these stomach contents can also lead to a precancerous condition called Barrett's esophagus and/or adenocarcinoma, a full blown cancer that is very aggressive and deadly. Drug Treatment of GERD Current medical treatment of GERD includes drugs, such as H2 blockers and proton pump inhibitors, which neutralize or suppress the stomach acid and help relieve symptoms. (PR Newswire)
OHSU findings may improve how people with chronic heartburn, precancer of the esophagus are screened Dec 4, 2006
Murphy was diagnosed with Barrett's esophagus, a precursor to cancer, four years ago ... "This trial has established that unsedated small-caliber endoscopy used in an office setting is technically feasible, well-tolerated and accurate in the screening and diagnosis of Barrett's esophagus. It's a more personal approach and represents the potential to eliminate the infrastructure and costs required for intravenous sedation. It's also more immediate. As soon as you're done, you can tell the patient... (EurekAlert!)
What Cures Your Aches Might Prevent Cancer Dec 1, 2006
Other gastroenterologists at Mayo are looking at NSAID use for patients with Barrett's esophagus. "There is evidence to support the idea that taking an NSAID will slow or reverse precancerous conditions such as Barrett's esophagus," Dr. Limburg says. (Newsmax)
Optical technique provides improved 'virtual biopsies' of internal surfaces Nov 20, 2006
Among potential applications for OFDI could be diagnosis of Barrett's esophagus, a precursor to esophageal cancer that can be identified with OCT, provided the affected tissue is scanned ... A National Institutes of Health-funded clinical trial of OFDI to monitor patients with Barrett's esophagus is currently underway at MGH, and a trial of potential cardiovascular applications should start up within the coming weeks. (EurekAlert!)
Holiday season could ring in 'heartburn season' Nov 15, 2006
" Avoiding foods that historically cause heartburn is the better strategy. "As a group, anything fatty and anything chocolate is likely to be causing a problem," he said. When to see a doctor Unfortunately, there's no simple answer to when heartburn sensations should prompt a visit to the doctor. Occasional heartburn usually doesn't signal a more complex problem, such as Barrett's esophagus or esophageal cancer. "But if you're taking medications daily, I think you should be concerned about it,"... (EurekAlert!)
Blocking Stomach Acid Doesn't Raise Cancer Risk Nov 3, 2006
The authors found some conditions for which acid-suppressing drugs are used, such as acid reflux disease, hiatal hernia and Barrett's esophagus, were associated with an increased risk of stomach and esophagus cancer. However, no apparent cancer risk was seen with other conditions, including peptic ulcer, gastritis, and indigestion. (MEDLINEplus)
Finding May Explain Biggest Cause Of Post-exercise Fainting Oct 14, 2006
(May 31, 2006) -- Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma). These studies will be presented Monday, May. (Science Daily)
Health Tip: Symptoms of Barrett's Esophagus Oct 2, 2006
Health Tip: Symptoms of Barrett's Esophagus - Forbes ... Health Tip: Symptoms of Barrett's Esophagus09 ... (HealthDay News) -- Barrett's esophagus is a condition in which damage to the cells that line the esophagus causes these cells to become abnormal. (Forbes)
Acid reflux may raise risk of cancer Sep 30, 2006
The condition is already linked to a disorder called Barrett's esophagus, which can in turn lead to oesophageal cancer. As for whether GERD is in fact a risk factor for laryngeal cancer, "definitive studies are yet to come," said Dr Michael Vaezi, a gastroenterologist at Vanderbilt University Medical Centre in Nashville and the study's lead author. (NEWS.com.au)
More Answers to Your Heartburn Questions Sep 26, 2006
Endoscopy will also help monitor for the development of a pre-cancerous condition called Barrett's esophagus, which can sometimes develop in people with chronic GERD. Bottom line: keep seeing your doctor for appropriate treatment and follow-up. Question: Does weight loss help to prevent GERD or does it have any impact. (ABC News)
The Serious Side of Heartburn Sep 19, 2006
The doctor discovered Fatone had developed a condition called Barrett's esophagus in which the normal cells that line the esophagus are replaced by cells that are much more likely to develop cancer. "The problem with Barrett's esophagus is that it is a premalignant condition, meaning that it can lead to esophageal cancer," said Dr. Roshini Rajapaska, a gastroenterologist at New York University Medical Center. (ABC News)
Researchers discover how acid reflux leads to esophageal cancer Aug 17, 2006
The study looked at human cancer cells and biopsies from patients with Barrett's esophagus (BE), a condition where cells in the esophagus have been altered by gastroesophageal reflux disease (GERD), or acid reflux. Acid reflux is believed to be a major risk factor for cancer in people with Barrett's esophagus ... It was previously known that levels of ROS are increased in Barrett's Esophagus and in esophageal cancer and that ROS may play an important role in the development of cancer. (EurekAlert!)
Hercules joins in Barrx $27.8M financing Jul 31, 2006
5 million in financing to Sunnyvale-based Barrx, a medical device company focused on the treatment of Barrett's esophagus, a precancerous condition of the esophagus. Hercules, founded in December 2003, provides debt and equity growth capital to technology-related companies at all stages of development. (San Jose Business Journal, CA)
SpectraScience Appoints Stanley Pappelbaum, M.D. as Director Jul 15, 2006
A new application for detecting pre-cancers in the throat, sometimes called Barrett's esophagus, is being tested in a clinical trial. Cancer of the esophagus is more than 90% fatal and may develop as a result of chronic heartburn or GERD. Esophageal cancer is growing five times faster than all other cancers. (PR Newswire)
Are cost controls bad medicine? Jun 30, 2006
" Through this "Hippocratic Oath," we doctors promise to care for our patients to the best of our abilities while respecting the medical decisions that need to be made. We promise to respect our patients and their needs, and to treat them with dignity. It is of the utmost importance that we diagnose and treat our patients in a timely manner without outside forces spurring us to make decisions that might not be appropriate. How, then, should doctors reconcile our desire to help our patients, to... (San Francisco Chronicle -- Opinion)
Mayo Clinic Studies Find Association Between Acid Reflux And Esophageal Cancer Jun 1, 2006
Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma) ... "But only about 5 percent of individuals who experience acid reflux will develop Barrett's esophagus," says Dr. Romero ... "And once Barrett's esophagus is diagnosed, patients have a 30- to 125-fold increased risk of developing esophageal cancer.". (Science Daily)
Study Shows More Than Half Of Esophageal Cancer Patients Now Survive Apr 13, 2006
For many people, the ring malfunctions consistently over time, allowing acid to irritate the cells lining the esophagus, which causes "heartburn" pain and GERD. Acid can also cause long-term changes in the esophageal cells that make them pre-cancerous, with the patches of abnormal cells known as Barrett's esophagus ... Of those people with frequent heartburn for five years or more, about one in five develop Barrett's esophagus, giving them a 40-fold higher than normal risk of developing... (Science Daily)
When antacids aren't enough Apr 10, 2006
An estimated 3% to 15% of people with GERD have this condition, which is called Barrett's esophagus ... Among people with Barrett's esophagus, the risk of developing adenocarcinoma esophageal cancer is 30 to 125 times higher than average, according to the National Institute of Diabetes & Digestive & Kidney Diseases ... After the meat was removed, Snell underwent an endoscopy and learned that he had Barrett's esophagus. (Los Angeles Times)
Photodynamic Therapy Is An Alternative To Removal Of Esophagus Apr 7, 2006
(April 28, 2005) -- A new camera-in-a-pill can help doctors diagnose and evaluate diseases of the esophagus including gastroesophageal reflux disease (GERD), erosive esophagitis and Barrett's esophagus (a pre-cancerous. . (Science Daily)
Evolutionary biology research techniques predict cancer Mar 27, 2006
To find out, the scientists decided to analyze data on a precancerous condition called Barrett's esophagus, in which cells lining the lower esophagus change due to repeated exposure to stomach acid from reflux, a condition often referred to as heartburn. Doctors typically adopt a "wait and watch" approach to treating patients with Barrett's esophagus because the condition only rarely leads to cancer and is difficult to treat surgically. (EurekAlert!)
'Pillcam' Shows Esophagus Damage Mar 24, 2006
About 12 percent of acid reflux patients have a condition called Barrett's Esophagus, which greatly increases the risk of esophageal cancer. The American Cancer Society estimates that 13,770 deaths from cancer of the esophagus will occur in 2006. (ABC News)
Curon Announces $3.0 Million Intellectual Property Transaction with BARRX Medical Mar 22, 2006
March 21 /PRNewswire-FirstCall/ -- Curon Medical, Inc. (Nasdaq: ) today announced that on March 16, 2006, it entered into an assignment and license agreement with BARRX Medical, Inc. for the assignment of United States Patent No. 6,872,206 and a worldwide, exclusive license of certain patents for the treatment of Barrett's esophagus ... Larry C. Heaton II, President and Chief Executive Officer of the Company, said "We are pleased to announce this mutually beneficial transaction with BARRX... (PR Newswire)
PDT Kills Drug-resistant Bacteria, Fungus In Lab Tests Mar 11, 2006
The drug Photofrin has been approved by the FDA as a sensitizer for PDT in the treatment of early and late stage endobronchial and esophageal cancers, as well as high-grade abnormal tissues associated with Barrett's esophagus, a peptic ulcer of the lower esophagus caused by the presence of cells that normally stay in the stomach lining. In the current research, after adding the light-sensitive drug Photofrin to the cultured samples and biofilm, the samples were exposed to various intensities... (Science Daily)
Richards Undergoes Tests, Consultations For Cancer Mar 10, 2006
Risk factors for esophageal cancer include long-term, heavy drinking of alcohol; tobacco use; and Barrett's esophagus, a condition associated with long-term reflux of stomach fluids that is often characterized by heartburn. Richards has acknowledged getting treatment in 1980 for alcoholism and for once being a heavy smoker. (Click2Houston, TX)
Light-based device probes for early cancer signs Mar 10, 2006
Acid reflux can lead to changes in the esophageal lining as the organ attempts to adapt to acids normally limited to the stomach, a condition called Barrett's esophagus, he explained. The condition raises the risk of esophageal cancer, and patients are generally tested for cancer periodically through random biopsy. (EurekAlert!)
Green Tea and Your Health Jan 7, 2006
More recently, in 2004, Harvard Medical School researchers found that a compound in green tea inhibits the growth and reproduction of cancer cells associated with Barrett's esophagus (a condition caused by stomach acid rising up into the esophagus causing the cells lining the esophagus to change, raising the risk of esophageal cancer by 30 to 40 times). Also, research indicates that drinking green tea lowers total cholesterol levels, as well as improving the ratio of good cholesterol (HDL) to... (Bella Online)
Long-Term Effects of GERD in Children Jan 1, 2006
PHILIP SHERMAN, MD: In the long term, irritation of the lining of the esophagus can result in trouble swallowing, difficulties in the passage of food and over a period of longer time, it can be fibrous, stricture formation and even longer term it appears there can be the formation of Barrett's esophagus, which at least in adults, is a precursor of a more serious warning sign of cancer of the esophagus. What may cause some children to develop long-term complications of GERD. (ABC News - Health)