Liver donor's family, recipient unite online Jul 8, 2008
She had been born with a genetic disorder called alpha-1 antitrypsin deficiency, which resulted in her body not producing enough of a key enzyme in the liver. Click for related content. (MSNBC -- Health)
Hepatocellular Carcinoma Jun 1, 2008
An Overview of a Malignant Cancer of the Liver. The diagnosis, treatment, and prognosis of this liver cancer can be burdensome for patients. (Suite101.com)
Mayo Clinic researchers find common gene disorder doubles risk of lung cancer, even among nonsmokers May 27, 2008
Researchers found that the genetic disorder, alpha-1 antitrypsin deficiency (1ATD), could explain up to about 12 percent of lung cancer patients in this study and likely represents the same widespread risk in the general population. "This is a seriously underdiagnosed disorder and suggests that people who have lung cancer and chronic obstructive pulmonary diseases (COPD) in their families should be screened for these gene carriers," says Ping Yang, M.D., Ph. (EurekAlert!)
Melissa Biggs, Fashion Designer and Former Baywatch Actress, Teams with CSL Behring to Raise Awareness of Alpha-1 Antitrypsin Deficiency, a Commonly Misdiagnosed Respiratory Disease May 18, 2008
Biggs Named Spokesperson for Education Campaign on Behalf of CSL Behring, maker of Zemaira(R), Alpha-1 Proteinase Inhibitor (Human) Augmentation Therapy KING OF PRUSSIA, Pa. May 17 /PRNewswire/ -- Melissa Biggs, a fashion designer and actress who appeared on Baywatch was recently named spokesperson for an education campaign on behalf of CSL Behring, and is urging Americans to get tested for alpha-1 antitrypsin (AAT) deficiency after her own diagnosis with the condition in 2005. (PR Newswire)
Kamada and PARI Expand Collaboration Feb 25, 2008
One of these agreements is for the conjoint clinical development of aerosolized AAT for treating the indications of Cystic Fibrosis (CF) and Bronchiectasis, in addition to Alpha-1 Antitrypsin Deficiency (AATD). Under the agreement PARI grants Kamada an exclusive license to use an optimized eFlow Electronic Nebulizer to deliver AAT in its clinical trials also for these indications. (BusinessWire)
Fear of insurance trouble leads many to shun or hide DNA tests Feb 25, 2008
She worried that she might not be able to get health insurance, or even a job, if a genetic predisposition showed up in her medical records, especially since treatment for the condition, alpha-1 antitrypsin deficiency, could cost over $100,000 a year. Instead, Grove sought out a service that sent a test kit to her home and returned the results directly to her. (International Herald Tribune)
Auction to benefit transplant prospect Sep 25, 2007
Crouch suffers from Alpha-1 antitrypsin deficiency, which has caused her lungs to operate on a 13-17 percent capacity. The Alpha-1 deficiency is an inherited disorder which causes a lack of the protein that protects people s lungs from damage caused by common sicknesses and air pollution such as tobacco smoke. (Hartford City News-Times, IN)
Mom who donated daughter's liver meets grateful recipient Sep 23, 2007
Mary Jo - "my friends call me Jo" - was diagnosed with Alpha-1 antitrypsin deficiency before she was 3. Her mother, Joyce Morris, remembers her daughter was given six months to live. (AZCentral -- News)
More of this story Jul 21, 2007
His youngest son Kevin has a condition called Alpha-1 Antitrypsin Deficiency, which may result in serious lung disease in adults. Kevin is healthy, but Kelley saw the Ironman as a way to educate people about the relatively unknown condition. (Brockton Enterprise, MA)
Phoenix to increase fines for illegal handicap parking Apr 13, 2007
My husband has emphysema as a result of an inherited lung disorder (Alpha 1 antitrypsin deficiency). He has difficulty walking short distances but continues to do as much of the grocery shopping & other errands as possible. (AZCentral -- News)
Klebsiella pneumoniae and Alpha 1 antitrypsin deficiency Jan 4, 2007
Dear Dr. Donohue: My 19-year-old grandson has been tentatively diagnosed with alpha 1 antitrypsin deficiency. I understand it is a disease of the liver and lungs. (Herald-Tribune)
Talecris Continues Global Expansion into Europe Dec 1, 2006
Commenting on Talecris' establishment of a European presence, Professor Claus Vogelmeier, M.D., Division of Pulmonary Diseases, University Hospital Marburg, Germany, said "We are pleased to continue working with Talecris, now in Europe, to help physicians identify and treat patients with alpha-1 antitrypsin deficiency, also known as genetic emphysema. Their commitment to invest in research projects and patient and professional support programs will continue to strengthen our ability to improve... (Canada Newswire)
Gene Therapy For Hereditary Lung Disease Advances Nov 23, 2006
An experimental gene therapy to combat alpha-1 antitrypsin deficiency, a common hereditary disorder that causes lung and liver disease, has caused no harmful effects in patients and shows signs of being effective, University of Florida researchers say ... But about 100,000 Americans have alpha-1 antitrypsin deficiency, according to the Miami-based Alpha-1 Foundation, a national not-for-profit organization devoted to finding a cure. (Science Daily)
WTC Workers Who Lack Gene Prone to Lung Injury Oct 26, 2006
"Alpha-1 antitrypsin deficiency is commonly associated with emphysema and other airway diseases like COPD," Prezant noted. It is involved in the inflammatory process and it may be a cause of the World Trade Center cough, which meets the definition of chronic cough syndrome, he said. (MEDLINEplus)
N.C. drug company lets patients watch medicine get made Sep 21, 2006
The 57-year-old former dancer from Durham has alpha-1 antitrypsin deficiency. The genetic disease affects about 1 in 2,500 Americans. (Herald Sun)
Transplant recipient's family carries on Aug 24, 2006
Christopher Urish, 25, was six when his mother, a school teacher, took ill from a genetic lung disorder called alpha-1 antitrypsin deficiency. She received the lungs of a 26-year-old Canadian woman at Toronto General Hospital in 1987, and Cathy Urish lived to be 50. (The Pantagraph newspaper)
Military Families Face Tough Choices Jul 28, 2006
Before Michael Boothe left for Iraq with his Kentucky National Guard unit, he knew his 3-year-old daughter Raygan was ill with an Alpha-1 antitrypsin deficiency, meaning she has an enzyme attacking her liver. When doctors who were preparing to biopsy her liver warned she could hemorrhage during the procedure, Boothe's wife, Sarah, contacted his unit commander and the Red Cross. (Forbes -- Technology)
Obituaries - 7/20/2006 Jul 20, 2006
In 1998, Lori was diagnosed with a genetic form of emphysema known as Alpha-1 Antitrypsin Deficiency, which forced her to give up her work. She then moved to Escondido to be near her family, a move we all treasured. (North County Times)
Read Greta's Blog Jun 8, 2006
My son Adam was born October 2005 and was diagnosed with Alpha 1 Antitrypsin Deficiency at 2 weeks old. Which is a genetic disorder that affects his liver and lungs. (Fox News)
