Blocking enzyme could help in rare blood cancer Sep 19, 2008
While most leukemias get their start in either lymph nodes or bone marrow, MLL cancer cells can originate from both. "These patients don't typically respond well to chemotherapy. There is a real need for better treatments," Cleary said in a telephone interview. (Reuters)
New Leukemia Signal Could Point Way To Better Treatment Sep 19, 2008
Most leukemias begin in just one of the body's two white blood cell factories, either the lymph nodes or the bone marrow. But in mixed-lineage leukemias, the bad cells can show markers from both kinds of tissue. (Science Daily)
New Synthetic Form Of Protein Holds Promise To Stop Cancer Spread Sep 19, 2008
It had been previously established that CXCL12 and its target cellular receptor, CXCR4, played an important role in the migration of cancer cells to common sites of tumor formation, such as bone marrow, lymph nodes, liver and lung tissue. Dr. Dwinell s laboratory established that CXCL12 expression was key to interfering with the progression of cancer. (Science Daily)
Time of hope, confusion in hunt for ovarian cancer tests Sep 18, 2008
Studies show even advanced patients can live many months longer if that very first operation is done by a gynecologic oncologist, who knows where cancer hides and how to remove pelvic lymph nodes, instead of the general surgeon most see today. "That's a big, big step forward for women because it allows them to get the proper care," says Dr. Richard Moore of Brown University, who led a study of Fujirebio Diagnostics Inc.'s so-called triage test that correctly predicted cancerous cysts more than... (Montana Standard, MT)
New procedure offers convenience to some breast cancer patients Sep 18, 2008
Mullins' doctors said she was a candidate for partial breast radiation because the lump was small -- less than two centimeters in size, the cancer was in an early stage and the cancer hadn't spread to her lymph nodes. Purviance said the radiation treatment isn't for all breast cancer patients. (Casper Star-Tribune, WY)
Kelli Pedroia warning teens about melanoma Sep 18, 2008
Kelli had a chunk the size of a large egg taken out of her right thigh and lymph nodes take out of her groin to make sure the cancer hadn t spread. The results showed the cancer had not spread, and thanks to the operation, was now gone. (Georgetown Record, MA)
Adding Taxotere To Chemotherapy Regimen Improves Survival In Early Breast Cancer, Study Suggests Sep 17, 2008
16, 2008) For patients with early stage breast cancer that has spread to the lymph nodes, adding four cycles of docetaxel (Taxotere) into a sequential regimen of epirubicin followed by cyclophosphamide, methotrexate and fluorouracil (CMF) reduces the risk of recurrence and death, updated long-term results show. See also. (Science Daily)
Natural History of HIV Sep 14, 2008
The latter is characterized by nonspecific symptoms such as fever, rash, pain, and swelling of lymph nodes (generalized lymphadenopathy) that occur within the first four weeks of contracting HIV and lasts for a few days to two weeks. Patients may later have mild to moderate depletions of red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). (Suite101.com)
Melrose People: Lindsay Sampson Doran Sep 13, 2008
As the cancer cells multiply, lymph nodes and other immune tissues become enlarged ... They found that my lymph nodes were enlarged, which can be due to infection but they couldn t find any infection, so they wanted me to follow up with my primary care doctor and a rheumatologist at MGH. I had to wait for three weeks to see the rheumatologist. (Melrose Free Press, MA)
Survival Instincts Propel 'Difficult Patient' To Insist On Quality Care Sep 13, 2008
11, 2008) A new study has found the majority of hospitals don't check enough lymph nodes after a patient's colon cancer surgery to determine if the disease has spread. Leading oncology organizations have. (Science Daily)
Benefit and Auction to be held for Local Family Tomorrow Night Sep 13, 2008
Breast cancer stages are based on the size of the tumor, whether lymph nodes are involved, if the cancer is invasive or non-invasive and whether the cancer has spread beyond the breast. Diedrichs is the wife of Joe Diedrichs. (Mid Iowa Enterprise, IA)
Anti-tumor therapy with endoscopic ultrasound may fight cancer more safely and effectively Sep 13, 2008
Used in conjunction with real time imaging, EUS can help physicians to detect blood flow in blood vessels in and around tumors as well as detect and biopsy tumors and lymph nodes as small as 3-5 mm. This allows doctors to avoid puncturing blood vessels when sampling tissue, get the most accurate view of the cancer and know exactly what stage a cancer is in for optimal therapy for treatment. This could save cancer patients with late stage disease from going through unnecessary surgery. (EurekAlert!)
U.S. Hospitals 'Flunk' Colon Cancer, Study Finds Sep 12, 2008
A new study from Northwestern University's Feinberg School of Medicine and the American College of Surgeons finds the majority of hospitals don't check enough lymph nodes after a patient's colon cancer surgery to determine if the disease has spread. Checking more lymph nodes is linked to improved survival of colon cancer because it allows doctors to accurately diagnose the stage of disease and prescribe the most effective treatment ... Over the past decade, a number of oncology organizations... (Science Daily)
GPC lockout stress adds to health, financial worries Sep 12, 2008
She immediately had surgery to remove five lymph nodes in her left breast. Two weeks later she had to have all of the lymph nodes and some tissue removed from the same breast. (Muscatine Journal, IO)
Health Buzz: Expected Primary Care Shortage and Other Health News Sep 11, 2008
One study, published online yesterday in the Journal of the National Cancer Institute, found that only 38 percent of U.S. hospitals sampled were testing enough lymph nodes after colon cancer surgery to accurately determine the extent to which the disease had spread. The other study, to be published in the October 15 issue of the journal Cancer, found that just 40 percent of people who'd received successful colon cancer treatment were getting all recommended follow-up tests. (U.S. News & World Report)
Let's be Neighbors Sep 11, 2008
Carol Clark went back to Jackson for her check-up following breast surgery and was happy to learn there were no signs of cancer in her lymph nodes. She will have to take radiation, but hopefully not chemo. (Louisville Winston County Journal, MS)
Radioisotope shortage could force delays in medical tests Sep 11, 2008
Used in 80% of nuclear medicine procedures, the drug also is used to measure kidney function and to gauge whether cancers have spread to the lymph nodes during some breast cancer surgeries. The impact on patients is "very serious," Atcher says. (USA Today -- News)
Most Hospitals Fall Short On Colon Cancer Sep 10, 2008
National guidelines say when colon cancer is removed, doctors should check at least 12 lymph nodes for signs of spread ... His team examined a national cancer database for records showing which hospitals checked 12 or more lymph nodes in at least 75 percent of eligible patients in 2004 and 2005, the latest data available. (CBS News)
Colon Cancer Treatments Need Improvements Sep 10, 2008
More lymph nodes should be checked, and follow-up care should be more frequent, studies find ... The first study, published in the Sept. 9 online edition of the Journal of the National Cancer Institute (JNCI), found that just 38 percent of U.S. hospitals sampled were testing enough lymph nodes after colon cancer surgery to accurately assess the extent to which the disease had spread ... When colon cancer is surgically removed, surgeons also remove surrounding lymph nodes to look for any signs... (U.S. News & World Report)
West Nile virus found in mosquitoes in Clayton Sep 10, 2008
Symptoms of West Nile virus include headache, fever, neck discomfort, muscle and joint aches, swollen lymph nodes and rash. In rare cases, the disease can lead to inflammation of the brain or spinal cord. (Atlanta Journal-Constitution -- Metro)
Can Breast MRI Help Evaluate Cancer? Sep 9, 2008
Can Breast MRI Help Evaluate Cancer. Breast Cancer Health Center. (WebMD)
* Doctors warn of risks of contracting milkers nodule Sep 9, 2008
Two weeks ago, a 56-year-old meat dealer, surnamed Wu (d), found a red lesion on her left thumb the size of a NT$1 coin and swollen lymph nodes in her left armpit ... Although no medication is required, if housewives continue to do housework with scabs on their hands, it can lead to bacterial infections and then cellulitis [infection of deeper parts of the skin] or lymphadenitis [inflamed lymph nodes], he said. (Taipei Times, Taiwan -- World)
Charity Young wins singing contest Sep 9, 2008
The caner has spread to Angelina's lymph nodes and hip bone and she is currently being treated by a specialist in Boston. Young and her friend Laura Mallas are leaders for Camp Fire USA, which is a group for boys and girls in kindergarten through second grade. (Mid Iowa Enterprise, IA)
Colon cancer patients not getting follow-up care Sep 9, 2008
5-year survival rates by stage Stage 1 (limited to colon): 93% Stage 2 (spread through wall of colon): 72% to 85% Stage 3 (spread to lymph nodes): 44% to 83% Stage 4 (spread to other organs): 8. Source: The American Cancer Society. (USA Today -- News)
Malignant Lymphoma and Autoimmune D... Sep 8, 2008
Lymphoma usually starts in lymph nodes or in clusters of lymphatic tissue, for instance lymphatic tissue lining the stomach or intestines ... Symptoms in NHL vary depending on the tissue affected and include unexplained weight loss, night sweats, fever, swollen lymph nodes, and abdominal bloating. (Suite101.com)
Genomic Health Announces Data Supporting Use of Oncotype DX(R) to Accurately Assess HER2 Gene Expression in Breast Cancer Patients Sep 7, 2008
The study analyzed 755 patients with 0 to 3 positive lymph nodes who were enrolled in Intergroup study E2197, a large adjuvant breast cancer trial evaluating two different chemotherapy regimens. The second study (Abstract 41) found a high degree of concordance -- 97 percent -- between RT-PCR using Oncotype DX and central laboratory FISH assessment of HER2 status. (PR Newswire)
Now what? Dealing with a Breast Can... Sep 6, 2008
Radiation is a bit more localized than chemotherapy, where x-ray technology is used to treat the areas around the breast (such as lymph nodes and chest wall) to kill off any stray cancer "seeds" that may have been traveling from the tumor site. Radiation treatment happens daily (5 days/week) for a number of weeks. (Suite101.com)
New Screening Catches More Breast Cancers Sep 5, 2008
Chemotherapy and treatment with Herceptin (trastuzumab) before surgery results in a "pathologic complete response," meaning no evidence of invasive disease in the breast or lymph nodes existed in many patients. Patients who did not have this complete response were three times more likely to have a recurrence, the researchers from M.D. Anderson reported. (MEDLINEplus)
Previstage(TM) GCC Colorectal cancer staging test featured in Expert Reviews article Sep 4, 2008
" Following on the work of Dr. Waldman, DiagnoCure developed the Previstage(TM) GCC Colorectal Cancer Staging Test at its U.S. CLIA-approved clinical laboratory. The GCC test was optimized to improve the processing of lymph node specimens and the test has shown very high analytical accuracy in detecting GCC levels consistent with the presence of occult metastases in the lymph nodes. "Dr. Waldman's studies support the value of Previstage(TM) GCC, developed by DiagnoCure. (Canada Newswire)
NCSU to offer bone-marrow transplants for dogs Sep 4, 2008
The machines, which cost about $80,000 each when new, harvest healthy stem cells from patients with lymphoma, a type of cancer that often originates in lymph nodes. The healthy cells are then reintroduced to the patient after total body radiation is used to kill the cancer cells left in the body. (Raleigh Triangle Business Journal, NC)
New nano device detects immune system cell signaling Sep 4, 2008
The reason for this is that the dendritic cells, T-cells and B-cells in the immune system, which tend to concentrate in the lymph nodes spread throughout the body, function as individual, unattached cells. If dendritic cells detect invaders in the body, they rapidly migrate to lymph nodes and have to find the appropriate T-cells to alert them ... But how dendritic cells attract the right T-cells among millions of cells within the lymph nodes remains an immunological puzzle. (EurekAlert!)
Stinging Caterpillars In Maryland Sep 4, 2008
Francis Breeding, a pest management consultant with the Queen Anne's County Extension Office, says a woman needed medical treatment last week because venom from a puss caterpillar traveled up her arm to her lymph nodes. Breeding says puss caterpillars don't bite, but their hair contains the venom. (W-USA News, DC)
Yeast Infections And Candidiasis Sep 3, 2008
Swelling of the lymph nodes. Extreme PMS. (Suite101.com)
Harsh soaps blamed for allergies Sep 3, 2008
The Langerhans cells then move from the skin to the local lymph nodes of the immune system, and induce an allergic response. Professor Callard said: "Despite its popularity over the past 20 years there is very little supporting evidence for the "hygiene hypothesis". "In contrast, there is mounting evidence from both studies of rare genetic conditions and our lab work to support an important role for abnormalities in the outer protective layer of the skin in allowing allergic sensitization. (Yahoo News -- Allergies and Asthma)
OR device inspired by the bionic man Sep 2, 2008
"Right now, we don't have a very good way to find lymph nodes that might have early signs of cancer," she said. "The beauty of his system is that with a very low amount of a chemicals that are safe, we can watch it move in real time and find the lymph nodes most likely to have cancer.". (Boston Globe)
Cincinnati football power Colerain off to a flying start Sep 2, 2008
"We found out (his dad's) tumor has not spread to his lymph nodes and his kid hasn't missed a beat. To see him make that play late in the game was something special.". Colerain's season could be something special, thanks to strenuous preseason workouts. (USA Today -- Sports)
Defra moves to quell public fears after woman begins treatment for ... Sep 2, 2008
R.J. Monies et al, Veterinary Record (2000), 140, 407-408) found that drinking unpasteurised milk was the most likely source of the infection, followed by eating the lymph nodes of infected rats. In all cases, infected cattle are the source of the disease, not wild animals. (Scotsman)
Newsweek:Preventative mastectomies on the rise Aug 28, 2008
My Stage IIIC breast cancer was diagnosed a year ago and underwent chemo, radical mastectomy, all lymph nodes removed from both my arm and neck followed by radiation ... My Stage IIIC breast cancer was diagnosed a year ago and underwent chemo, radical mastectomy, all lymph nodes removed from both my arm and neck followed by radiation ... My Stage IIIC breast cancer was diagnosed a year ago and underwent chemo, radical mastectomy, all lymph nodes removed from both my arm and neck followed by... (MSNBC -- Health)
West Nile disease spreads Aug 28, 2008
Symptoms include fever, headache, body aches, skin rash and swollen lymph nodes. People infected so far this year range in age from 15 to 78. (Sioux City Journal, IO)
Jade Goody: Think of your kids, says cancer mum Aug 27, 2008
You might not have the same treatment as me - I thought I was going to have a hysterectomy at first but then they discovered that, as well as the 5cm tumour, the cancer had spread to some of my lymph nodes and my stomach. So instead, I was told I'd have six cycles of chemo, involving one week of treatment at Velindre Hospital, near Cardiff, then two weeks off. (Mirror.co.uk)
Where the rain falls, mosquitoes will follow Aug 27, 2008
West Nile Virus symptoms include, in mild infections, fever, headache and body aches, which are often accompanied by a skin rash and swollen lymph nodes. More severe infections are less common. (Catskill Daily Mail, NY)
Research examines variations of rare lung disease Aug 27, 2008
LAM occurs when an unusual type of cell begins to grow out of control and spread to restricted areas in the body, including the lungs, kidneys, lymph nodes and vessels. A team led by Jean Elwing, MD, an assistant professor in UC's pulmonary, critical care and sleep division, is enrolling female LAM patients to see if pulmonary hypertension and pulmonary vascular disease may be contributing to their respiratory symptoms. (EurekAlert!)
DiagnoCure receives approval from the U.S. regulatory authorities and launches its Previstage(TM) GCC Colorectal Cancer Staging Test Aug 26, 2008
Current standard of care requires that pathologists microscopically examine a thin slice of tissue from the lymph nodes harvested during the patient's surgery to see if cancer has spread. Currently, up to 25 - 30 percent of patients with no pathologically-positive lymph nodes (stage I and II cancers) later develop recurrent disease, presumably through occult metastases that have escaped detection. (Canada Newswire)
Cancer slows UConn coach Calhoun but doesn't stop him Aug 26, 2008
A portion of his salivary gland and 37 lymph nodes that were found to be cancer-free also were removed. Calhoun, 66, lost about 20 pounds and a little hair behind his right ear. (USA Today -- Sports)
The truth about cervical cancer Aug 25, 2008
"In surgery, we remove the lymph nodes, uterus, some tissues and sometimes even some parts of the vagina," adds Dr Batla. In Western countries, the cases of cervical cancer have come down due to the active awareness, vaccine and pap screenings which detect the cancer at a very early stage. (India Times, India)
More of this story Aug 24, 2008
On Jan. 10, Angela had surgery to remove a center portion of her tongue and nearby lymph nodes. Angela endured 42 radiation treatments in eight weeks, receiving chemotherapy every three weeks, losing her hair and 187 pounds after treatment. (Searcy Daily Citizen, AR)
Christina Applegate shows us how to be strong Aug 24, 2008
I have not yet undergone genetic testing, and will not know whether chemo has killed the remaining invasive cancer cells in my right breast or the bad cells in my lymph nodes until several months from now. One can only pray that with good science and faith, the correct decisions are made. (New Haven Register, CT)
Behind the screen Aug 23, 2008
" An Australian audit published last year by the Royal Australasian College of Surgeons revealed too many women with DCIS were having operations on the lymph nodes in their armpits - which can result in swelling and restricted movement - without good evidence the procedures were warranted. For those women, it can be argued that screening mammograms intended to protect their health led directly to excessive surgical treatment, although others may benefit from having more minimal lumpectomy... (Sydney Morning Herald -- Australia)
Wyoming officials confirm fifth case of plague found in mountain lions Aug 23, 2008
If your cat develops a fever and has swollen lymph nodes, it is time to call a veterinarian. Comments. (Great Falls Prairie Star, MT)
Stem Cell Marker For Aggressive Bowel Cancer Aug 23, 2008
In stages one and two, the cancer has not spread to the lymph nodes and is still local to the original site, so patients normally have surgery to remove the cancer from that part of the bowel. Patients don't as a rule have chemotherapy for these early stages because they are usually elderly and frail and it could do more harm than good. (Medical News Today)
Christina Applegate's Mastectomy: FAQ Aug 22, 2008
One of the side effects of breast cancer treatment when lymph nodes are removed or scarred is lymphedema. It causes painful swelling in the arm near the affected breast. (WebMD)
Sniffing out cancer Aug 21, 2008
Leffell said the concept might also be more significant if it applied to melanoma, a less common but far more deadly form of skin cancer that is very treatable when detected before it spreads to the lymph nodes. In fact, scientists at Monell will soon begin studying patients to develop an odor profile for melanoma. (Philadelphia Inquirer)
Stem Cell Indicator For Bowel Cancer Should Lead To Better Survival Rates Aug 21, 2008
In the two earlier stages, before the cancer involves the lymph nodes, patients normally have an operation to remove the cancer from the bowel. They are rarely given chemotherapy in addition to the surgery. (Science Daily)
Imaging System Lets Doctors 'See' Cancer During Surgery Aug 21, 2008
In preliminary trials, the researchers used FLARE to visualize organs and body fluids of mice and map the lymph nodes of pigs, all in real time. The first human clinical trials, which may begin this summer, will involve mapping the lymph nodes of breast cancer patients. (MEDLINEplus)
Bone marrow stem cells may help control inflammatory bowel disease Aug 21, 2008
Analysis of the animal's lymph nodes revealed that MSC treatment produced a significant reduction in inflammation. Surprisingly, cell-tracking studies indicated that the MSCs which were administered by infusion into the peritoneum, the membrane lining the abdominal cavity moved into abdominal lymph nodes rather than to the intestine itself ... "The intestine may be an ideal site for MSC therapy, given its rapid ability to regrow tissue and its extensive local supply of lymph nodes; and the... (EurekAlert!)
100-Mile Ride for Leukemia, Lymphoma Society Is Saturday Aug 20, 2008
Although it starts in the bone marrow, it can spread to the blood, lymph nodes, spleen, liver, central nervous system and other organs. 100-Mile Ride. (Missourian Publishing, MO)
Medical opinion: Sometimes no treatment is the best treatment Aug 18, 2008
These can progress to pain and increasing difficulty hearing and, if not treated, can advance and spread to adjacent structures, causing painful swelling of face, neck lymph nodes and also fever and discharge. In the early stages, the infection can be managed by drying the ears and using over-the-counter eardrops containing 70 percent ethyl alcohol or simple homemade mixture of equal parts of vinegar and alcohol. (Yuma Daily Sun, AZ)
Antibody Drug Unleashes Tumor-Killer T Cells Aug 16, 2008
based company Micromet, Inc., report in this week's Science that in a 38-person trial designed primarily to determine the safety of their drug blinatumomab (which incorporates the protein), 11 showed significant responses to therapy that included a shrinking of cancerous lymph nodes. Here's how it works: The two-pronged protein is part of a fleet of such antibodies that Micromet calls BiTEs (bispecific T cell engagers), which like to stick to proteins on the surfaces of cancer cells and the... (Scientific American)
Cancer and immunotherapy Q and A Aug 16, 2008
One 52-year-old man, who was suffering from advanced skin cancer that had spread to his lymph nodes and one lung, was free of tumours eight weeks of treatment. So why do we need this new kind of immunotherapy. (Telegraph.co.uk)
Prototype test for predicting clinical outcome for melanoma patients Aug 15, 2008
More than 70% of patients with Stage III melanoma melanoma that has spread to the lymph nodes will typically have a rapid time to progression (TTP) to Stage IV melanoma, and pass away within five years of their diagnosis. However, the remaining. (EurekAlert!)
Grieving friends, family try to make sense of loss Aug 14, 2008
Symptoms include tiring easily and inflamed lymph nodes. While many people can live for years with the form of leukemia without severe symptoms, the disease progresses quickly in others, for whom treatment is recommended. (Boston Globe)
MS drug may work against viral infection: study Aug 14, 2008
FTY720 among other things traps white blood cells -- key soldiers in the immune system's fight against infections -- in the lymph nodes, Altman said. With viral infections, the lymph nodes are where the immune response can get primed and started, Altman said ... Some viruses replicate themselves at high levels in lymph nodes, including the human immunodeficiency virus that causes AIDS.. (Scientific American)
Targeted Radiation Therapy Can Control Limited Cancer Spread Aug 14, 2008
11, 2006) Patients with lung cancer that has spread to mediastinal lymph nodes -- located between the chest, breastbone and spine -- who receive radiation after surgery and chemotherapy live twice as long as. (Mar. (Science Daily)
Experimental Chemotherapy Regimen Shows Promise In Treating Advanced Lung Cancer Aug 14, 2008
11, 2006) Patients with lung cancer that has spread to mediastinal lymph nodes -- located between the chest, breastbone and spine -- who receive radiation after surgery and chemotherapy live twice as long as. (June 23, 2004) Oncologists at Rush University Medical Center, Chicago, are studying what they believe may be the wave of the future for treating patients with advanced stage lung cancer: individualized targeted. (Science Daily)
Trapping White Blood Cells Proves Novel Strategy Against Chronic Viral Infections Aug 14, 2008
But preventing white blood cells' circulation by trapping them in the lymph nodes can help mice get rid of a chronic viral infection, researchers at Yerkes National Primate Research Center and the Emory Vaccine Center have found ... Altman and his co-workers found that infecting mice with the Armstrong strain sequesters white blood cells in the lymph nodes, while clone 13 does so less stringently ... His team turned to an experimental drug called FTY720, which prevents white blood cells from... (Science Daily)