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Elderly people are more prone to both anemia and polycythemia because they're more likely to have health problems that affect red blood cells, such as kidney disease, gastrointestinal bleeding, malnutrition or cancer. The elderly are also more likely to have heart disease, which makes them more vulnerable to the stresses of surgery and puts them at greater risk of post-operative heart attacks and other cardiac complications. (Science Daily)
CMS Coverage Proposal for Erythropoiesis-Stimulating Agents (ESAs) Jeopardizes Cancer Clinical Practice and Patient Access Jun 14, 2007
PROCRIT is also not indicated for the treatment of anemia due to other factors such as iron or folate deficiencies, hemolysis or gastrointestinal bleeding, which should be managed appropriately. Important U.S. Safety Information for PROCRIT From the Boxed Warnings -- Use the lowest dose of PROCRIT that will gradually increase the hemoglobin (Hb) concentration to the lowest level sufficient to avoid the need for red blood cell (RBC) transfusion. (PR Newswire)
Abnormal Red Blood Cell Count Spells Trouble in Surgery Jun 13, 2007
Older people are also more at risk of having other underlying diseases, such as kidney disease, gastrointestinal bleeding or cancer, all of which can affect red blood cell levels. The current study, which appears in the June 13 issue of the Journal of the American Medical Association, examined data from 310,311 veterans over the age of 65 who had non-cardiac surgeries. (Forbes)
What's in a word: Spearfish family loses only daughter to Zellweger Syndrome - today they fight for a cure Jun 7, 2007
Most infants do not survive past the first six months, and usually succumb to respiratory distress, gastrointestinal bleeding or liver failure. It was on July 13, 2005 that Makenzie started having some intestinal bleeding. (Black Hills Pioneer, SD)
Can Aspirin Help Fight Cancer? Jun 6, 2007
"[Aspirin's] potentially positive benefits must be weighed against the potential risks associated with aspirin use, such as gastrointestinal bleeding and hemorrhagic (bleeding) stroke." ... However, Bardia and colleagues caution that "these potentially positive benefits must be weighed against the potential risks associated with aspirin use, such as gastrointestinal bleeding and hemorrhagic (bleeding) stroke.". (CBS News)
Aspirin May Keep Colon Cancer Away May 25, 2007
"It's important to determine if there are individuals that will benefit significantly enough to outweigh the potential risks of gastrointestinal bleeding.". Part of the problem is that there's currently no way to know who's at risk for cox-2-expressing colon cancers, and aspirin had little effect on colon cancers that didn't express the cox-2 enzyme. (MEDLINEplus)
More of this story May 20, 2007
There were a total of 93 deaths of 38,501 patients from cardiac arrest, gastrointestinal bleeding, gastrointestinal leak, pulmonary embolism, respiratory arrest and small bowel obstruction ... 73-percent and gastrointestinal bleeding at 0. (Auburn Citizen, NY)
A baby aspirin a day is healthy; but more than that can be dangerous May 14, 2007
While doses of 162 to 325 milligrams (the strength of an adult aspirin) were found appropriate for acute situations in which platelet formation needs to be blocked quickly, taking such doses on a daily basis over a period of years was associated with gastrointestinal bleeding. Doses of 81 and 325 milligrams are most commonly prescribed in the United States, although the evidence clearly favors the lower amount, Campbell says. (Boston Globe)
Baby Aspirin Safer Than Full-Strength for Cardiac Patients May 11, 2007
That's particularly true for gastrointestinal bleeding, reported Charles L. Campbell, M.D., of the University of Kentucky here, and colleagues ... Although most data indicated that an increase in the aspirin dose was linked to an increased risk of gastrointestinal bleeding, the clinical importance of these findings when associated with contemporary doses of 75 to 325 mg still remains poorly defined, the researchers said. (Newsmax)
Baby Aspirin Effective in Preventing Heart Attacks May 10, 2007
Higher doses of aspirin have not been shown effective at preventing cardiovascular disease long-term and are linked to gastrointestinal bleeding, according to the report, which was published in the today. Dr. Charles Campbell, the lead author of the report, said now is the time for adults taking a full adult dose of aspirin for blood thinning the prevention of clots to ask their doctors if a lower dose might be more appropriate for them. (FOX News)
Baby Aspirin Better For Your Health, Study Says May 10, 2007
The study, which is published in today's issue of the Journal of the American Medical Association, found that doses higher than a baby aspirin, 75 to 81 mg, are no better at preventing cardiovascular events long-term and are associated with increased risk of gastrointestinal bleeding. Gill Heart Institute cardiologists and University of Kentucky College of Medicine faculty Dr. Charles Campbell, Dr. Steven R. Steinhubl and Dr. Susan Smyth, along with Dr. Gilles Montalescot of the Instjtut de... (Science Daily)
Drug Safety: There's No Magic Pill May 10, 2007
For instance, few people know that aspirin carries a high risk of gastrointestinal bleeding. "It's nice to have a rigorous evaluation of not just one drug vs. the other, but some of the more risky pharmaceuticals compared to things that are widely done in day-to-day life," added Dr. A. Mark Fendrick, co-director of the University of Michigan Center for Value Based Insurance Design, and professor at the University of Michigan Medical School and University of Michigan School of Public Health in... (MEDLINEplus)
Low-Dose Aspirin Best for Preventing Heart Attack May 10, 2007
Higher doses of aspirin, which are commonly prescribed, don't offer better protection and are associated with increased risks of gastrointestinal bleeding, the study authors said. "We wanted to find out whether there was strong evidence favoring higher or lower doses of aspirin," said lead author Dr. Charles L. Campbell, an assistant professor of medicine at the University of Kentucky. (MEDLINEplus)
Baby aspirin better for your health, University of Kentucky study says May 9, 2007
(May 9, 2007) " Nearly a quarter of a million Americans each year may be hospitalized with bleeding complications caused by needlessly taking a daily dose of an adult-sized aspirin rather than a baby aspirin to prevent a heart attack or stroke. A study by a group of UK HealthCare Linda and Jack Gill Heart Institute cardiologists found that the commonly prescribed 325 mg adult tablet may be more than many people need each day. The study, which is published in today's issue of the Journal of the... (EurekAlert!)
Over-the-counter drug concern May 5, 2007
They all had gastrointestinal bleeding, a side effect of excessive ibuprofen use. One of the patients was taking 30 tablets a day - compared to the recommended maximum dose of six. (BBC News -- Health)
Aspirin: A wonder drug for women? May 2, 2007
Younger women and their doctors will need to weigh whether the benefits outweigh the risks of gastrointestinal bleeding. Hayes also points out that aspirin seems to elevate the risk of hemorrhagic stroke in women. (Orlando Sentinel)
Prilosec Helps Control Bleeding in Ulcer Patients Apr 20, 2007
"In someone presenting with upper gastrointestinal bleeding, acid suppression using proton pump inhibitor should be initiated early and certainly in someone waiting for endoscopy," said study lead author Dr. James Y.W. Lau, of The Chinese University of Hong Kong. Although treatment with proton pump inhibitors is often initiated before an endoscopy, data on the practice has been lacking. (MEDLINEplus)
Daily Aspirin May Reduce Cancer Risk Apr 19, 2007
"The American Cancer Society doesn't recommend using aspirin to prevent cancer, because aspirin can cause serious gastrointestinal bleeding," he added. His team published its findings in the April 17 issue of the Journal of the National Cancer Institute. (MEDLINEplus)
Omeprazole before Endoscopy in Patients with Gastrointestinal Bleeding Apr 19, 2007
Methods Consecutive patients admitted with upper gastrointestinal bleeding underwent stabilization and were then randomly assigned to receive either omeprazole or placebo (each as an 80-mg intravenous bolus followed by an 8-mg infusion per hour) before endoscopy the next morning. Results Over a 17-month period, 638 patients were enrolled and randomly assigned to omeprazole or placebo (319 in each group). (New England Journal of Medicine)
Aspirin May Protect Against Cancer Apr 18, 2007 Study: Too Few Take Aspirin For Heart Apr 11, 2007 Plavix Appears To Be Safe During And After Heart Bypass Mar 29, 2007 Long-Term Aspirin Use Cuts Death Risk for Women Mar 28, 2007 Task force urges Americans not to take aspirin, other painkillers as colon cancer preventive Mar 25, 2007 Churg-Strauss Syndrome Mar 22, 2007 New to cancer arsenal Mar 19, 2007 EMT, others ready for race Mar 8, 2007 FROM OUR READERS: Nursing settlement a great deal for all Feb 25, 2007 Guidelines for preventing heart disease in women revised Feb 22, 2007 Napoleon felled by ulcers, cancer, says study Jan 18, 2007 Mystery of Napoleon's death solved? Jan 17, 2007 Napoleon's Mysterious Death Unmasked Jan 17, 2007 Air Care flight nurse logs 1,000 flights Jan 5, 2007 READ MORE > Jan 3, 2007 FDA proposal stresses caution on painkillers Jan 2, 2007 FDA label proposal reinforces caution on common painkillers Jan 2, 2007 Cure that kills: Better warnings will help medicine consumers Jan 2, 2007
"Aspirin may have anticancer effects, but it also has it own risks, chiefly an increased risk of gastrointestinal bleeding. Talk to your doctor about the risks and benefits." ... "Aspirin may have anticancer effects, but it also has it own risks, chiefly an increased risk of gastrointestinal bleeding. Talk to your doctor about the risks and benefits," Bardia says. (CBS News)
Aspirin linked to lower cancer risk Apr 18, 2007
In an accompanying editorial in the journal, Maria Elena Martinez and Robert Greenberg at the Arizona Cancer Centre note that the benefits of aspirin must be weighed against an increased risk of gastrointestinal bleeding and stroke. Special reports. (Guardian Unlimited -- Life)
It can have serious side effects, such as gastrointestinal bleeding, heartburn, and stomach upset. But everyone at increased risk of heart disease should discuss aspirin use with a doctor. (CBS News)
Overall, they found that patients who took clopidogrel and aspirin experienced less gastrointestinal bleeding and fewer strokes and other cardiovascular complications than patients who were on aspirin alone. "The new off-pump strategy is a proven surgical advance in the treatment of heart disease," Dr. Whellan says. (Science Daily)
For intermediate-risk women, aspirin can be considered if blood pressure is under control and the benefits are believed to outweigh risks, such as gastrointestinal bleeding. But the decision to take aspirin, or any other medication, should not be made by an individual alone, Chan said. (MEDLINEplus)
"I think for the general population, the risk of either having some gastrointestinal bleeding from aspirin or cardiovascular side effect from some of these other medications ... probably outweighs their use for colon cancer," he said. On the Net. (North County Times)
Second phase consists of peripheral blood eosinophilia as well as eosinophilic tissue infiltrates causing a condition known as Loeffler s syndrome, chronic eosinophilic pneumonia or eosinopholic gastroenteritis; in some patients gastrointestinal bleeding and abdominal pain or mesenteric ischemia can occur. Third Phase is characterized by systemic vasculitis affecting the skin, cardiovascular system, gastrointestinal tract, and peripheral nervous system; kidney disease can occur but it less... (Suite101.com)
Government health officials warned earlier this month against daily aspirin use to reduce the risk of colorectal cancer because of potential side effects from gastrointestinal bleeding to kidney damage ... Adding nitric oxide to aspirin, Rigas said, helps prevent gastrointestinal bleeding and other side effects that have been associated with the drug. (Newsday -- Health)
Her father had suffered from gastrointestinal bleeding. Though he had no previous symptoms, an ulcer may have burst inside him. (Las Vegas Review-Journal -- Nevada News)
Numerous studies have shown that inadequate staffing leads to adverse outcomes for patients, including higher rates of urinary tract infection, pneumonia, shock and upper gastrointestinal bleeding. In the worst case scenario, a patient can face a higher risk of dying while in the hospital if cared for by a nurse who has been assigned too many patients. (Las Vegas Review-Journal -- Opinion)
Doctors say it's important to note that women of child-bearing years need folic acid to reduce the risk of birth defects and that no one should begin taking aspirin, which sometimes causes gastrointestinal bleeding, without consulting a doctor. The association recommends a daily baby aspirin for all women 65 and older, as long as their blood pressure is under control. (Contra Costa Times)
The autopsy descriptions show that Napoleon's stomach was filled with a dark material that resembled coffee grounds, an indication of gastrointestinal bleeding that likely was the immediate cause of death, according to Genta. The doctors then compared the descriptions against modern images of 50 benign ulcers and 50 gastric cancers. (CNET News.com)
Researchers say gastrointestinal bleeding was immediate cause of death ... However, a new study combining current medical knowledge, reports, Bonapartes physician memoirs, eyewitness accounts, and medical histories found that gastrointestinal bleeding was the immediate cause of death. (Huntington WSAZ-TV, WV)
The analysis, which also refutes rumors of arsenic poisoning, points to gastrointestinal bleeding as the likely immediate cause of death ... The autopsy descriptions show that Napoleon's stomach was filled with a dark material that resembled coffee grounds, an indication of gastrointestinal bleeding that likely was the immediate cause of death, Dr. Genta said. (Science Daily)
Noncardiac medical emergencies treated aboard the helicopter include stroke, respiratory distress, gastrointestinal bleeding and abdominal aortic aneurysms. According to Mercy's flight records, approximately 40 percent of the patients receiving care in 2006 were trauma victims requiring advanced treatment at the regional trauma center at Mercy. (Sioux City Journal)
Non-cardiac medical emergencies treated aboard the helicopter last year included stroke, respiratory distress, gastrointestinal bleeding and abdominal aortic aneurysms. When asked why Mercy Air Care might have made a record number of flights last year, Dr. Thomas Benzoni, the program's medical director, said, "Provide a good service for which there is a need. It is really that simple."The crew is trained to ask, 'I'm from Mercy Air Care; I'm here to help. (Sioux City Journal, IO)
Doctors have known for years that nonsteroidal anti-inflammatory drugs can cause kidney damage and gastrointestinal bleeding in some patients, even when taken at recommended dosages. They've also known acetaminophen can cause severe liver damage when taken at higher than recommended doses or in combination with three or more alcoholic drinks per day. (Boston Globe)
Doctors have known for years that NSAIDs can cause kidney damage and gastrointestinal bleeding in some patients, even when taken at recommended dosages. They've also known acetaminophen can cause severe liver damage when taken at higher than recommended doses or in combination with three or more alcoholic drinks per day. (The Standard-Times, MA)
All this can, and does, lead to appalling side effects, including liver damage, gastrointestinal bleeding, kidney injury or even death. To reduce those risks, the U.S. Food and Drug Administration is mandating new labels, which include fluorescent or bold-faced type on labels prominently placed on containers. (Pittsburgh Post-Gazette, PA)
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