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A 60-patient Phase 2 trial in patients undergoing multi-vessel coronary artery bypass graft (CABG) surgery has enrolled 15 patients to date in Greece and the U.K.. A 100-patient Phase 2 trial in patients with peripheral vascular disease who are undergoing limb amputation below or through the knee has enrolled seven patients to date in South Africa, and patient screening has begun in the U.K.. (CNBC -- Research Alerts)
HALT: Help acronyms leave (medical) trials Aug 13, 2006
Today's Globe Opinion Politics Magazine Education Science NECN Special reports Obituaries. THERE'S A cardiology clinic in Minneapolis that specializes in patients with difficult-to-treat heart disease, known by doctors as ``no option" disease because neither surgery nor placing a stent is likely to be helpful. When a cardiologist started the clinic several years ago, he thought about naming it the No Option Clinic. But it quickly dawned on him that such an appellation would probably backfire. At... (Boston Globe)
Allon Files CTA to Add Canadian Sites to Phase II Clinical Trial Aug 2, 2006
VANCOUVER, BRITISH COLUMBIA--(CCNMatthews - Aug. 2, 2006) - Allon Therapeutics Inc. (TSX: - ), The Neuro Protection Company(TM), today announced that it has filed a Clinical Trial Application (CTA) with Health Canada to gain approval to begin recruiting Canadian patients into its ongoing Phase II human clinical trial evaluating the Company's product AL-208 as a treatment for the mild cognitive impairment that commonly occurs following coronary artery bypass graft (MCI post-CABG) surgery ... The... (CCNMatthews Press Releases)
ev3 Receives FDA Clearance for SpideRX(TM) Embolic Protection Device for Saphenous Vein Graft Angioplasty Jun 27, 2006
As many as one-third of patients experience significant blockages in the grafted vessel(s) within 12 years following CABG surgery and, as a result, may be treated with an endovascular procedure including either balloon angioplasty or stenting. These procedures often dislodge small particles ("emboli") that can block small down stream arteries and possibly damage heart muscle and cause a heart attack. (PR Newswire)
Hardening of Arteries Significantly Reduced by Vegetable Diet Jun 19, 2006
Coronary artery bypass graft (CABG) surgeryuses a vein from another part of the body to bypass a severely blocked coronary artery. PREVENTION. (SeniorJournal.com)
Case School Of Engineering Professor Applies Virtual Reality To Train Brain And Heart Surgeons Mar 3, 2006
" Another undertaking Cavusoglu's "robotic beating heart surgery" project is also advancing surgical science. In a joint program with the University of California at Berkeley funded by the National Science Foundation, Cavusoglu and several Case doctoral students are building a prototype robot that will allow surgeons to routinely perform open surgery on a beating rather than a stopped heart, minimizing risk to the patient. Designed to stabilize and track the heart's motion, the robot would... (Science Daily)
State makes push for death rate data Feb 19, 2006
It is noteworthy and gratifying that this surgeon has had no CABG (coronary artery bypass graft) mortalities thus far in 2005," according to a report sent to the health department on Dec. 28, 2005. The department asked the hospital for information on Dec. 19, after being notified by the hospital of its 2004 mortality rate, Dreyer said.The January report referred to Moses as ''an outlier surgeon," a term Moses' lawyer, Paul Cirel, objected to in an interview. He said the hospital found no... (Boston Globe)
FDA's Public Health Advisory for Trasylol - full coverage Feb 9, 2006
On January 26, 2006, The New England Journal of Medicine (NEJM) published an article by Mangano et al. reporting an association of Trasylol (aprotinin injection) with serious renal toxicity and ischemic events (myocardial infarction and stroke) in patients undergoing coronary artery bypass grafting surgery (CABG) ... The study reported in the NEJM was an observational study of patients undergoing CABG who received either Trasylol, one of two other drugs intended to decrease peri-operative... (Food Consumer)
CABG Medical Announces Plan to Cease Operations and Review Strategic Alternatives Feb 9, 2006
CABG Medical, Inc. logo ... MINNEAPOLIS, Feb. 8 /PRNewswire-FirstCall/ -- CABG Medical, Inc. (Nasdaq: ) (the Company) today announced it will substantially reduce the scope of operations in anticipation of a possible dissolution of the Company and concurrently initiate a formal process to evaluate strategic alternatives ... SOURCE CABG Medical, Inc. Web Site: Photo Notes: NewsCom: APArchive: PRN Photo Desk. (PR Newswire)
FDA Grants Priority Review to PLAVIX(R) (Clopidogrel Bisulfate) Supplemental New Drug Application (sNDA) for Additional Type of Heart Attack Jan 18, 2006
Acute Coronary Syndrome (ACS) For patients with ACS (unstable angina/non-Q-wave MI), including patients who are to be managed medically and those who are to be managed with percutaneous coronary intervention (with or without stent) or coronary artery bypass graft surgery (CABG), PLAVIX has been shown to decrease the rate of a combined end point of cardiovascular death, MI, or stroke as well as the rate of a combined end point of cardiovascular death, MI, stroke, or refractory ischemia. Important... (PR Newswire)
Stereotypical Attitudes Lead to Health Inequities Jan 7, 2006
Dr. Michele van Ryn from University of Minnesota Medical School, Minneapolis, and colleagues evaluated the factors associated with whether or not doctors recommended coronary artery bypass graft surgery (CABG) for heart patients ... Only 21 percent of black men were recommended for CABG, the investigators report, compared with 40 percent of white and Hispanic men ... Physicians' recommendation for CABG was significantly associated with their perception that the patient wanted a physically active... (MEDLINEplus)
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