UPDATE 1-FDA backs Astra's Seroquel XR for bipolar disorder Oct 11, 2008
UPDATE 1-FDA backs Astra's Seroquel XR for bipolar disorder ... LONDON, Oct 10 (Reuters) - U.S. regulators have approved AstraZeneca's (AZN.L: , , , ) drug Seroquel XR as a treatment for bipolar disorder, extending the medicine's use beyond schizophrenia, the Anglo-Swedish company said on Friday ... The green light from the Food and Drug Administration makes Seroquel XR the first medication cleared in the United States for the once-daily acute treatment of both depressive and manic episodes... (Reuters)
Bipolar Disorder In Children Appears Likely To Continue Into Young Adulthood Oct 11, 2008
10, 2008) About 44 percent of individuals who had bipolar disorder as children continue to have manic episodes as young adults, according to a report in the October issue of Archives of General Psychiatry, one of the JAMA/Archives journals. This rate, along with the severity of the disease at young ages, strongly suggest that bipolar disorder can be continuous from childhood to adulthood, the authors note ... Recent data has demonstrated an enormous increase in the diagnosis of pediatric bipolar... (Science Daily)
Patty Duke puts celebrity face on bipolar disorder Oct 11, 2008
Welcome to bipolar disorder, and its violent mood swings ... I really felt like most of the things that seemed wrong were the result of the environment I found myself in, said Duke, who spoke about bipolar disorder in Missoula on Friday night. (Missoulian, MT)
Life of the party may be at risk Oct 11, 2008
Experts say some people are more susceptible to developing serious psychological conditions such as schizophrenia or bipolar disorder, which can be triggered by drug and alcohol abuse ... Evidence shows people with bipolar disorder are five times more likely to be alcoholics than the general population. (Sydney Morning Herald -- Australia)
Club stoush bowls out member Oct 11, 2008
A MAN suffering from bipolar disorder and depression has been barred from membership at a Sydney bowling club after a clash over club bylaws. Lawn bowls is John Randall's passion and he regards it as valuable therapy for his illness, so he is devastated that Pittwater Memorial Bowling Club has turned its back on him. (Sydney Morning Herald -- Australia)
Link of creativity, mood disorders pondered Oct 11, 2008
Certain characteristics of his prose -- hypersensitivity and constant rumination, or persistent contemplation -- reflect a pattern of temperament that some psychology researchers say connects mental illness, especially bipolar disorder and depression, with creativity. There have been more than 20 studies that suggest an increased rate of bipolar and depressive illnesses in highly creative people, says Kay Redfield Jamison, professor of psychiatry at Johns Hopkins University and author of the "An... (CNN -- Health)
Jack Layton asked to address CRTC scandal: PM Stephen Harper nicknamed 'subPrime Minister' for his failure to stop corporate welfare scam Oct 10, 2008
"I trust that Mr. Layton will make his decision on the need for a public inquiry into the CRTC affair on the basis of the documented evidence, not on the basis of my diagnosis with bipolar disorder. I am not in the mood for discrimination", concluded Mahar. For further information: Keith. (Canada Newswire)
Mental health awareness rally today at Capitol Oct 10, 2008
Hozid said there is a variety of illnesses that fall under the mental health umbrella, with bipolar disorder, schizophrenia, and depression being three of the most common. Substance abuse must also be taken into account when discussing mental health awareness, he said. (Juneau Empire)
Pfizer `Spun' Unfavorable Neurontin Drug Studies, Experts Say Oct 10, 2008
In documents filed yesterday in federal court in Boston, the experts said Pfizer had a ``publication strategy'' to suppress negative reports in medical journals while promoting ``off-label'' uses for Neurontin that weren't approved by federal regulators, such as treating bipolar disorders ... The notion that Pfizer and Warner-Lambert Co. somehow systematically suppressed negative studies related to bipolar disorder is directly contradicted by Warner-Lambert's support of the publication in the... (Bloomberg)
Younger Lecture to discuss mental health issues, parenting Oct 10, 2008
Phelps is an expert on bipolar disorders ... He has written extensively on bipolar disorder. (Corvallis Gazette Times, OR)
Q&A with Patrick Lencioni, The Table Group Oct 10, 2008
Congress passed legislation expanding the Americans with Disabilities Act so that people with treatable diseases like diabetes, epilepsy and bipolar disorder are covered. The ADA Amendments Act was a response to court rulings that narrowed ADA coverage beyond what Congress intended. (East Bay Business Times, CA)
Early Bipolar Disorder Often Persists to Adulthood Oct 10, 2008
Between episodes, most people with bipolar disorder are free of symptoms However, up to 33 percent may have residual symptoms and a small percentage will have chronic unremitting symptoms, despite treatment. The research team, from Washington University in St. Louis, studied the 8-year outcomes of participants a study called the "Phenomenology and Course of Pediatric Bipolar Disorders." Funded by the NIMH, the study included 115 children between 7 and 16 years old (the average age was 11 years)... (MEDLINEplus)
Lawsuit alleges Pfizer manipulated drug studies Oct 8, 2008
In the case of Pfizer's Neurontin, the negative studies would have increased doubts about the drug's value for several unapproved uses - treating bipolar disorder, controlling certain types of pain and preventing migraine headaches, according to the specialists' opinions. So-called off-label use of Neurontin for those conditions helped propel its sales to nearly $3 billion a year before it lost patent protection in 2004. (International Herald Tribune -- Health)
Texas wins piece of Eli Lilly settlement Oct 8, 2008
Since that time, the had also approved Zyprexa for the treatment of varying degrees and maintenance of bipolar disorder. Despite medical expert warnings of unforeseen side effects such as weight gain, diabetes, hyperglycemia and cardiovascular complications, Lilly (NYSE: LLY) began an aggressive deceptive marketing campaign in 2001, according to the attorney general s office. (Houston Business Journal, TX)
Dow: How Low Can You Go? Oct 8, 2008
Back in 2004, the drug company's that it "promoted Neurontin for uses not approved by the Food and Drug Administration, including bipolar disorder and chronic nerve pain," notes the WSJ. This new case consolidates lawsuits by health insurers and consumers who claim they were misled into purchasing Neurontin and want a refund$4. 9 billion, to be precise. (Slate)
E.Lilly to pay $62 mln to settle Zyprexa case -NYT Oct 7, 2008
Zyprexa is an anti-psychotic drug that calms hallucinations associated with schizophrenia and bipolar mania but internal Lilly documents and e-mail messages appear to show that the drug was marketed to patients with dementia and milder forms of bipolar disorder, the paper added. A spokesman and a lawyer for Lilly did not return a call and an e-mail message for comment, the paper said. (Reuters)
Lilly's $6.5B ImClone deal called bold, risky Oct 7, 2008
ZyprexaTreats schizophrenia, bipolar disorder. 2007 sales: $4. (Indianapolis Star)
Kulongoski seeks more than Oct 7, 2008
Oregon and 32 other states have reached a $62 million settlement with Eli Lilly and Co. over the marketing of Zyprexa, an anti-psychotic drug used to treat schizophrenia and bipolar disorder. Lawsuits filed by the states accuse Eli Lilly of deceptively marketing Zyprexa for unapproved "off-label" uses and failing to adequately disclose the drug's potential side effects. (OregonLive, OR -- Business)
Local Briefs Oct 7, 2008
Individuals will be invited to fill out a one-page questionnaire, which could be used to assess the likelihood that a person may have depression, bipolar disorder, generalized anxiety disorder or post-traumatic stress disorder, according to the news release. There also will be an opportunity to hear an educational presentation, receive pamphlets and brochures and follow up privately with a mental health professional if necessary, according to the news release. (DeKalb Daily Chronicle, IL)
Angst Is Rising, but Many Must Forgo Therapy Oct 7, 2008
April Jones, who lost her job as a paralegal last year, recently negotiated with both her therapist and her psychiatrist to continue treatment for her bipolar disorder at a rate she could afford. Ms. Jones, a single mother in Plattsmouth, Neb. (Wall Street Journal)
Woman charged with child abuse sentenced Oct 7, 2008
Seven hours later, Jackson, who suffers from bipolar disorder, drove to her mother-in-law's with her child and seemed to be under the influence. Deputy Commonwealth's Attorney Bryan Haskins said witnesses noted Jackson's condition as having trouble walking, slurring her speech and cursing. (Chatham Star Tribune, VA)
Fighting for proper care - State NAMI head took up cause after losing stepbrother to PTSD, suicide Oct 6, 2008
It names depression, bipolar disorder, schizophrenia and severe anxiety as examples of mental illness ... Academy- and Emmy-award winner Patty Duke will speak about bipolar disorder from 7 to 9 p.m. Friday, Oct. 10, in the University Center Ballroom at the University of Montana. (Missoulian, MT)
Carrie Fisher shares her struggles in 'Wishful Drinking' Oct 5, 2008
Threaded throughout the performance is her struggle with bipolar disorder and drug addiction ... In Fisher's case, it's a severe case of bipolar disorder that, she says, leaves her locked up inside her home, manic. (Boston Globe)
Concert a tribute to suicide victim Oct 5, 2008
Then a student at Guilderland High School, she got counseling and was diagnosed with bipolar disorder. Over the next decade, she endured various medications and treatments under the care of therapists. (Albany Times Union)
Bailout legislation boosts Texans' mental health coverage Oct 5, 2008
The 1997 law, which affects about 20 percent of working Texans, requires coverage of autism, bipolar disorder, schizophrenia, schizoaffective disorder, obsessive compulsive disorder, major depressive disorder, childhood depression and paranoia and psychosis. Comments. (Houston Chronicle)
New Class of Drugs Might Cause Congenital Heart Defects Oct 4, 2008
The only drug now on the market that targets GSK-3 is lithium, given to treat bipolar disorder. It is a relatively weak GSK-3 inhibitor. (MEDLINEplus)
New York police officer commits suicide over Taser incident Oct 3, 2008
Morales suffered from depression, schizophrenia and bipolar disorder. The day of the incident, he did not recognize his mother, she said, and he was naked and talking about dying. (Los Angeles Times)
Father's love transcends machete attack Oct 3, 2008
For a decade, Corey wrestled with the riddle of adolescence and bipolar disorder, trying to untangle what bad behavior Leland could control and what he couldn't ... About two in every 10 people in the system have a serious chronic mental illness like schizophrenia or bipolar disorder, many times the percentage of seriously mentally ill people in the general population, according to Laura Brooks, mental health director for the state Department of Corrections. (Anchorage Daily News)
Loss Of The Protein Target Of Lithium Disrupts Normal Mouse Embryonic Heart Development Oct 3, 2008
3, 2008) One drug used to treat bipolar disorder is lithium, an inhibitor of GSK-3 proteins controversially linked to congenital heart defects ... Individuals with bipolar disorder are usually treated with 'mood stabilizing' drugs, one of which is lithium an inhibitor of GSK-3 proteins. (Science Daily)
'Hub' Of Fear Memory Formation Identified In Brain Cells Oct 3, 2008
"Psychiatrists have used lithium to treat mania and bipolar disorder for decades, but how it works is not well-understood," Ressler says. "Importantly, we gave the mice one acute dose of lithium, rather than letting it build to a stable level like in the clinical situation. It's not clear whether there is a connection between mood regulation and how lithium functions in our experiments with fear memory.". (Science Daily)
Over 65 and living with depression Oct 3, 2008
About one in five people over the age of 65 living in the community suffer from diagnosable mental illnesses such as depression, bipolar disorder or schizophrenia - about the same rate as the general population. But the data exclude residents of nursing homes, retirement homes and long-term-care facilities, where rates of mental illness range from 40 to 90 per cent.. (Globe and Mail)
Mini movie reviews Oct 3, 2008
A Summer in the Cage - Filmmaker Ben Selkow's feature-length documentary chronicling his friend Sam's battle with manic-depressive illness, also known as bipolar disorder. By showing the difficult emotional impact of being bipolar on Sam, his family and the filmmaker, the film hopes to put a human face on an illness that affects millions of American families. (Athens Banner-Herald)
Policeman kills himself after fatal Taser accident Oct 3, 2008
He had been diagnosed with bipolar disorder but his behaviour became uncontrolled after a change in his medication, family members said. Police say they had ordered an inflatable bag to be brought to the scene, but it had not arrived when Mr Morales was stunned. (Sydney Morning Herald -- World)
Common Gene Mutation Lowers Risk for Bipolar Disorder Oct 3, 2008
MONDAY, Sept. 29 (HealthDay News) -- New research suggests that a missing section of DNA in a certain gene may hold the key to whether a person does or does not develop bipolar disorder. "[Our] findings show that a natural, common mutation in the GRIK4 gene protects against bipolar disorder," said Ben Pickard, lead author of a study in this week's issue of the Proceedings of the National Academy of Sciences and a member of the department of medical genetics at the University of Edinburgh in... (MEDLINEplus)
Mental-Health Bill on Tap Sep 25, 2008
She said she spent $4,619 out-of-pocket on medical care last year, mostly to treat her bipolar disorder. To save money, she said she often waits to get treatment until her condition worsens. (Wall Street Journal)
The orphans of medicare Sep 25, 2008
Ms. Clark, a hairdresser who suffers from bipolar disorder and paranoia, had been to the emergency room earlier and was discharged ... In the community, family doctors do the bulk of treatment by default, but they are rarely equipped to deal with the complexity of care required by patients with severe depression, bipolar disorder or schizophrenia ... The Archie Courtnall Centre named after the father of former National Hockey League stars Russ and Geoff Courtnall who suffered from bipolar... (Globe and Mail)
The working wounded Sep 25, 2008
Yet the vast majority of Canadians suffering from mental illness such severe conditions as depression, bipolar disorder and schizophrenia are not in hospital but in the community and at work. Mental illness accounts for a stunning 40 per cent of disability claims and sick leaves in Canada. (Globe and Mail)
Alexza inhaler is making strides Sep 25, 2008
7 million bipolar disorder patients in the United States who suffer from acute episodes of agitation. Anticipation of and news about the trial results pushed the company s stock above $6 a share, well above its 52-week low of $3. (San Jose Business Journal, CA)
Behind Green Gables Sep 25, 2008
The five published volumes show an unhappy existence in a lifeless marriage to a Presbyterian minister who suffered from what today is called manic depression, or bipolar disorder. In 1941, she wrote one line: Oh God, such an end to life. (Globe and Mail)
Patients Stay With Phone Psychotherapy Longer Than Office Visits Sep 24, 2008
5, 2007) Patients taking medications to treat bipolar disorder are more likely to get well faster and stay well if they receive intensive psychotherapy, according to results from the Systematic Treatment. . (Science Daily)
S.F. Man Found Slain In Humboldt County Sep 23, 2008
Rana "was very bright and very gifted" but suffered from depression and bipolar disorder, she said. He used medical marijuana to ease his symptoms, she said. (San Francisco Chronicle -- Crime)
Taleo's SaaS Approach Keeps Bringing Profits Genotyping Gets Less Expensive Sep 23, 2008
Such diseases include alcohol dependence, bipolar disorder, glaucoma, kidney disease, neuroblastoma, obesity and schizophrenia. People can take a printout of their genetic journals to their doctors, says 23andMe co-founder Linda Avey. (Investors Business Daily)
Officer cleared in fatal shooting Sep 23, 2008
SAN DIEGO The officer who shot and killed a San Diego man suffering from bipolar disorder in May has been cleared of any wrongdoing by the District Attorney's Office, officials said Monday. Officer Javier Carranza was justified in fatally shooting Alexander James Culley on May 30, according to a four-page memo from District Attorney Bonnie Dumanis. (San Diego Union-Tribune)
Mental Health Court succeeds Sep 22, 2008
So the court, which is funded by a $916,000 grant from the California Department of Corrections and Rehabilitation, tries to hold people accountable while dealing with underlying issues, such as depression, bipolar disorder, schizophrenia or post-traumatic stress disorder. "Years ago, this probably would have been a no-go," said Mike Wilson, coordinator for Mental Health Court with the county's Behavioral Health and Recovery Services. (Modesto Bee, CA)
Britney, more one time Sep 21, 2008
She was reported to be suffering from bipolar disorder. September 7, though, brought a return to what passes for comparative normality. (Sydney Morning Herald -- Entertainment)
Growing up Bipolar Sep 21, 2008
He has suffered from bipolar disorder his whole life, as have both of his parents and his one brother - only a sister, the Peggy named in the excerpt on the facing page, escaped mental illness ... You've suffered crippling effects from bipolar disorder for much of your life. (Boston Globe)
Man pleads not guilty to murder, assault charges Sep 21, 2008
Tardif also said Porter suffered from bipolar disorder and had been prescribed several medications, including lithium. Porter was already arraigned in Framingham District Court on June 25 and held on $250,000 bail. (Framingham TAB, MA)
Man: DCFS led to baby's death Sep 21, 2008
Carter acknowledged that she suffers from depression, bipolar disorder and that she has bouts of schizophrenia when she is not taking her medication. Scovil said he had problems with alcohol in the past and had two DUIs, the last one about 10 years ago. (Atlanta Journal-Constitution)
18-month sentence in NY presidential letters theft Sep 20, 2008
Renehan, of North Kingstown, R.I., said the crime occurred when he was in the manic phase of what was later diagnosed as bipolar disorder. He pleaded guilty this year to interstate transportation of stolen property. (San Francisco Chronicle -- Crime)
Stress hits mental health workers Sep 19, 2008
Allison Kokany lost her job in aged care because of her bipolar disorder - at that point undiagnosed and unmedicated - but her illness was the perfect qualification for her next position as a consumer worker in a public mental health service. Her role - to support newly diagnosed people and help them navigate the legal minefield around mental illness - put her on the front line of patient care, and she adored it. (Sydney Morning Herald -- Australia)
Farewell to a patriot Sep 19, 2008
Although not all suicide victims have a depressive episode, suicide can be seen in schizophrenia, bipolar disorder and many other conditions. In teens, suicide can be seen as resulting from acute loss and combined substance abuse, occasionally with no evidence of depression. (NJ.com -- Times)
WASH POST: Drudge-ology 101... Sep 18, 2008
Drudge-ology 101: McCain, Obama and Media Bias - The Fix. Play the electoral outcome prediction game. (The Drudge Report)
Girl's bath killing 'not planned' Sep 18, 2008
" Bipolar disorder In January 2003, shortly before Naomi was born, Ms Hill was diagnosed with chronic anxiety and the following April, she had a "hypermanic" episode. Dr O'Halloran suggested this indicated a bipolar disorder. Naomi was born 10 weeks premature in a "difficult" birth in the June, she told the court. Almost immediately, Ms Hill suffered a severe form of post natal depression but appeared to make a quick recovery after treatment by her local community health team. She was... (BBC News)
Mylan gets FDA approval for generic antipsychotic drug Sep 17, 2008
Risperdal is used to treat schizophrenia and bipolar disorder. The drug had annual U.S. sales of approximately $2. (Pittsburgh Business Times, PA)
The new R&D: Repair and develop Sep 16, 2008
Modifications of existing drugs, the compounds are intended for use in the treatment of epilepsy, bipolar disorder and migraine headaches ... The drugs for epilepsy, bipolar disorder and migraines, all drugs called valproates, rose to the top of the list. (Raleigh Triangle Business Journal, NC)
The bipolar puzzle Sep 16, 2008
James, then 10, had been given a diagnosis of bipolar disorder two years earlier ... Like many children whose emotional problems are being diagnosed as bipolar disorder, his main symptoms are aggression and explosive rage (known in clinical parlance as "irritability"), and those traits have been visible in James from the time he was a toddler ... Fifteen years ago his condition would probably not have been called bipolar disorder, and some doctors might hesitate to diagnose it in him even now,... (International Herald Tribune)
Woman sentenced in hit and run Sep 16, 2008
She said she had bipolar disorder, post-traumatic stress disorder, migraines, high-blood pressure and breathing problems. Pope, who has no criminal history, pleaded no contest to attempted second-degree assault, driving under the influence of intoxicants and hit-and-run driving. (OregonLive, OR -- News)
Risks found for youths in new antipsychotics Sep 15, 2008
Studies have found that more than 80 percent of prescriptions for atypical antipsychotics for children are to treat something other than schizophrenia, like autism-related aggression, bipolar disorder or attention-deficit problems. Some of these are approved uses; others are not. (International Herald Tribune -- Health)
A tribute to how families function Sep 15, 2008
When her father was 17, he was diagnosed with what at the time was called manic depression; what's now referred to as bipolar disorder. Toews grew up not understanding why her father was sometimes an intelligent, caring, funny man and why sometimes he disappeared into a "dark heaviness," as she puts it. (Globe and Mail -- Entertainment)
Grant funds mental illness hot line Sep 15, 2008
Telephone support groups also will be available for people with specific diagnoses, such as bipolar disorder. The Warm Line operates from 5:30-9:30 p.m. Monday through Friday and from 1-5 p.m. Saturday. (Missoulian, MT)
Shock treatment successful for many patients Sep 13, 2008
He d like to marry some day but doesn t obsess over it, knowing a bipolar disorder doesn t exactly make him a catch. Early in the diagnosis, he said, he was too accepting of it. (Columbus Telegram, NE)
Immaturity Of The Brain May Cause Schizophrenia Sep 11, 2008
Among their findings, mice heterozygous for a null mutation of the alpha-isoform of calcium/calmodulin-dependent protein kinase II show profoundly dysregulated behaviors, including a severe working memory deficit and an exaggerated infradian rhythm (cycle of increases and decreases in locomotor activity in their home cage; 2-3 weeks/cycle), which are comparable to the symptoms observed in patients with schizophrenia, bipolar disorder and other psychiatric disorders. Despite extensive research,... (Science Daily)
Seeing doubles in Dear Leader's no-show Sep 10, 2008
"He suffered from diabetes, heart disease, liver disorder, lung problem and bipolar disorder.". Kim collapsed last month, the Chosun Ilbo newspaper reported on Tuesday, quoting a South Korean official in Beijing. (Asia Times Online)
Speaker delivers message on importance of mental health Sep 10, 2008
Szabo told the audience of his past struggles with bipolar disorder, depression and even a suicide attempt while he was in high school. He was able to open up to his father about the issues he was tryng to deal with on his own. (The Daily Campus, CT)
Mother gets prison for deadly crash Sep 9, 2008
He also said Parker suffers from bipolar disorder and had a panic attack that caused her to flee from police. Juliano asked Judge Kim Martusewicz for probation and no prison time for his client, who he said still grieves over the deaths. (Auburn Citizen, NY)